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Target Details

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Name:70 kDa zeta-associated protein
Uniprot name:ZAP70_HUMAN
Accession Numbers:A6NFP4 P43403 Q6PIA4 Q8IXD6 Q9UBS6
EC-Number:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1M61 1U59 2OQ1 2OZO
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
()-oxazepam hemisuccinate sodium salt44329184BindingDB-show
1,2,4-Oxadiazole Analogue 105329202BindingDB-show
1,2,4-Oxadiazole Analogue 115329203BindingDB-show
1,2,4-Oxadiazole Analogue 12a5329204BindingDB-show
1,2,4-Oxadiazole Analogue 12b5329220BindingDB-show
1,2,4-Oxadiazole Analogue 12c5329221BindingDB-show
1,2,4-Oxadiazole Analogue 12d5329222BindingDB-show
1,2,4-Oxadiazole Analogue 12e5329205BindingDB-show
1,2,4-Oxadiazole Analogue 12f5329206BindingDB-show
1,2,4-Oxadiazole Analogue 12g5329207BindingDB-show
1,2,4-Oxadiazole Analogue 13a5329223BindingDB-show
1,2,4-Oxadiazole Analogue 13b5329224BindingDB-show
1,2,4-Oxadiazole Analogue 13c5329225BindingDB-show
1,2,4-Oxadiazole Analogue 14a6326460BindingDB-show
1,2,4-Oxadiazole Analogue 14b5329209BindingDB-show
1,2,4-Oxadiazole Analogue 14c6326461BindingDB-show
1,2,4-Oxadiazole Analogue 14d6326462BindingDB-show
1,2,4-Oxadiazole Analogue 14e5329212BindingDB-show
1,2,4-Oxadiazole Analogue 14f6326463BindingDB-show
1,2,4-Oxadiazole Analogue 15a5329226BindingDB-show
1,2,4-Oxadiazole Analogue 15b5329227BindingDB-show
1,2,4-Oxadiazole Analogue 15c5329228BindingDB-show
1,2,4-Oxadiazole Analogue 4a5329214BindingDB-show
1,2,4-Oxadiazole Analogue 4b5329179BindingDB-show
1,2,4-Oxadiazole Analogue 4c5329180BindingDB-show
1,2,4-Oxadiazole Analogue 4d5329181BindingDB-show
1,2,4-Oxadiazole Analogue 4e5329182BindingDB-show
1,2,4-Oxadiazole Analogue 4f5329215BindingDB-show
1,2,4-Oxadiazole Analogue 4g5329183BindingDB-show
1,2,4-Oxadiazole Analogue 4h5329184BindingDB-show
1,2,4-Oxadiazole Analogue 4i5329185BindingDB-show
1,2,4-Oxadiazole Analogue 4j5329216BindingDB-show
1,2,4-Oxadiazole Analogue 4k5329186BindingDB-show
1,2,4-Oxadiazole Analogue 5a6326454BindingDB-show
1,2,4-Oxadiazole Analogue 5b6326455BindingDB-show
1,2,4-Oxadiazole Analogue 5d5329217BindingDB-show
1,2,4-Oxadiazole Analogue 5e5329218BindingDB-show
1,2,4-Oxadiazole Analogue 5f6326464BindingDB-show
1,2,4-Oxadiazole Analogue 5g5329189BindingDB-show
1,2,4-Oxadiazole Analogue 5h6326456BindingDB-show
1,2,4-Oxadiazole Analogue 5i6326457BindingDB-show
1,2,4-Oxadiazole Analogue 5j6326459BindingDB-show
1,2,4-Oxadiazole Analogue 5k5329194BindingDB-show
1,2,4-Oxadiazole Analogue 5l5329195BindingDB-show
1,2,4-Oxadiazole Analogue 5m5329196BindingDB-show
1,2,4-Oxadiazole Analogue 5n5329197BindingDB-show
1,2,4-Oxadiazole Analogue 65329198BindingDB-show
1,2,4-Oxadiazole Analogue 75329199BindingDB-show
1,2,4-Oxadiazole Analogue 85329200BindingDB-show
1,2,4-Oxadiazole Analogue 95329201BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
3-substituted indolin-2-one 11a5329138BindingDB-show
3emg25113172BindingDB-show
7-Cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine6603792BindingDB-show
7MP10062694BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:64960344422592BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL10276510347718BindingDB-show
CHEMBL10276610031003BindingDB-show
CHEMBL108119811755812BindingDB-show
CHEMBL108551124762205BindingDB-show
CHEMBL11217218545623BindingDB-show
CHEMBL1122639927800BindingDB-show
CHEMBL11234620579089BindingDB-show
CHEMBL11251818545605BindingDB-show
CHEMBL11256118545643BindingDB-show
CHEMBL11262318545586BindingDB-show
CHEMBL11318515550318BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL124297746929544BindingDB-show
CHEMBL124320046929748BindingDB-show
CHEMBL124332646929857BindingDB-show
CHEMBL125891311847343BindingDB-show
CHEMBL127023024809764BindingDB-show
CHEMBL13010944353601BindingDB-show
CHEMBL13108644353421BindingDB-show
CHEMBL1312569939626BindingDB-show
CHEMBL13177344353160BindingDB-show
CHEMBL20538644353173BindingDB-show
CHEMBL20914811467730BindingDB-show
CHEMBL21580316046126BindingDB-show
CHEMBL21594316086114BindingDB-show
CHEMBL24635617748275BindingDB-show
CHEMBL24746811684933BindingDB-show
CHEMBL24786611626406BindingDB-show
CHEMBL26372144313930BindingDB-show
CHEMBL26425744353525BindingDB-show
CHEMBL26577744313931BindingDB-show
CHEMBL2708510248747BindingDB-show
CHEMBL2819579869943BindingDB-show
CHEMBL30816444314373BindingDB-show
CHEMBL30873410100735BindingDB-show
CHEMBL31111444313990BindingDB-show
CHEMBL31917944332978BindingDB-show
CHEMBL31921044329185BindingDB-show
CHEMBL32037212968822BindingDB-show
CHEMBL32107944333009BindingDB-show
CHEMBL3220669888491BindingDB-show
CHEMBL32375520579088BindingDB-show
CHEMBL32457615550319BindingDB-show
CHEMBL32591215550320BindingDB-show
CHEMBL33697544353260BindingDB-show
CHEMBL38666116086104BindingDB-show
CHEMBL3867879988860BindingDB-show
CHEMBL4177344286666BindingDB-show
CHEMBL41935312968819BindingDB-show
CHEMBL4195399985193BindingDB-show
CHEMBL41975715550321BindingDB-show
CHEMBL42067218545657BindingDB-show
CHEMBL43082544313929BindingDB-show
CHEMBL43350744314380BindingDB-show
CHEMBL44359244329458BindingDB-show
CHEMBL45145044589516BindingDB-show
CHEMBL45321744593471BindingDB-show
CHEMBL45542811675054BindingDB-show
CHEMBL45751944589025BindingDB-show
CHEMBL45878844589023BindingDB-show
CHEMBL45880610457649BindingDB-show
CHEMBL45897344589050BindingDB-show
CHEMBL45914644589051BindingDB-show
CHEMBL47017544590150BindingDB-show
CHEMBL47078044590204BindingDB-show
CHEMBL47172744593470BindingDB-show
CHEMBL47177644593472BindingDB-show
CHEMBL47181920741385BindingDB-show
CHEMBL47247825169255BindingDB-show
CHEMBL47259022958832BindingDB-show
CHEMBL47284044578663BindingDB-show
CHEMBL47322944593475BindingDB-show
CHEMBL47458210022152BindingDB-show
CHEMBL47518044593467BindingDB-show
CHEMBL47524944593469BindingDB-show
CHEMBL47525425169256BindingDB-show
CHEMBL47537112017518BindingDB-show
CHEMBL47557544589022BindingDB-show
CHEMBL47560944589002BindingDB-show
CHEMBL47588244578662BindingDB-show
CHEMBL47653744578584BindingDB-show
CHEMBL47674144578586BindingDB-show
CHEMBL47716544578626BindingDB-show
CHEMBL47864244578661BindingDB-show
CHEMBL48197325138151BindingDB-show
CHEMBL48217525138153BindingDB-show
CHEMBL48435044588972BindingDB-show
CHEMBL48520444589001BindingDB-show
CHEMBL48573044589515BindingDB-show
CHEMBL48573144589517BindingDB-show
CHEMBL48675144589514BindingDB-show
CHEMBL50008644565801BindingDB-show
CHEMBL5091619856983BindingDB-show
CHEMBL51167011324412BindingDB-show
CHEMBL51181144590205BindingDB-show
CHEMBL51231944590149BindingDB-show
CHEMBL51391544578627BindingDB-show
CHEMBL51436544578585BindingDB-show
CHEMBL51505444589024BindingDB-show
CHEMBL5157579817349BindingDB-show
CHEMBL51913125138152BindingDB-show
CHEMBL52066944588971BindingDB-show
CHEMBL52084244589000BindingDB-show
CHEMBL55710145273358BindingDB-show
CHEMBL55978745269074BindingDB-show
CHEMBL56494045267327BindingDB-show
CHEMBL57250845482622BindingDB-show
CHEMBL5725629905577BindingDB-show
CHEMBL57301945482618BindingDB-show
CHEMBL57302645482637BindingDB-show
CHEMBL57348345482611BindingDB-show
CHEMBL57348445482612BindingDB-show
CHEMBL57348845482613BindingDB-show
CHEMBL57371945482623BindingDB-show
CHEMBL57395945482626BindingDB-show
CHEMBL57438545482656BindingDB-show
CHEMBL57459945482653BindingDB-show
CHEMBL57483945482615BindingDB-show
CHEMBL57484145482624BindingDB-show
CHEMBL57504645482629BindingDB-show
CHEMBL57504845482644BindingDB-show
CHEMBL57505245482625BindingDB-show
CHEMBL57525245482628BindingDB-show
CHEMBL57526645482647BindingDB-show
CHEMBL57845045482616BindingDB-show
CHEMBL58379145482648BindingDB-show
CHEMBL58414845482614BindingDB-show
CHEMBL58417045482627BindingDB-show
CHEMBL58457045482621BindingDB-show
CHEMBL58475845482619BindingDB-show
CHEMBL58963046224908BindingDB-show
CHEMBL59132546225169BindingDB-show
CHEMBL59775446233287BindingDB-show
CHEMBL59922445139989BindingDB-show
CHEMBL59942845139991BindingDB-show
CHEMBL6912922736235BindingDB-show
CHEMBL7635010461517BindingDB-show
CHEMBL7693744314402BindingDB-show
CHEMBL7763844313997BindingDB-show
CHEMBL9912544329183BindingDB-show
CHIR-26511656518BindingDB-show
CID 1009754410097544BindingDB-show
CID 1009754410028975BindingDB-show
CID 98443209844320BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
diarylurea deriv. 1445840BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
K00592a9549296BindingDB-show
L2G9549184BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
nchembio.117-comp91400BindingDB-show
nchembio.90-comp111715767BindingDB-show
NVP-TAE68416038120BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Pyrrolo[2,3-d]pyrimidine 16539952BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
Semaxinib5329098BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine451705BindingDB-show
staurosporine44299148BindingDB-show
STAUROSPORINE44259DrugBank-show
SU-1481310138259BindingDB-show
SU66685329099BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
70 kDa zeta-associated protein
Syk-related tyrosine kinase
Tyrosine-protein kinase ZAP-70
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
KSYK_HUMAN69.452.5
LCK_HUMAN39.925.8
FYN_HUMAN39.927.1
YES_HUMAN39.625.4
SRC_RAT38.525.1
SRC_HUMAN38.225
SRC_RSVSE38.126
ITK_HUMAN3824
HCK_HUMAN37.924.5
CSK_HUMAN3725.7
NTRK1_HUMAN35.321.9
FGFR4_HUMAN35.321.6
FGFR2_HUMAN33.922
Q99052_MOUSE3319.8
ARAF_HUMAN32.720.8
KPCA_BOVIN32.520.8
RAF1_RAT32.419.3
KPCA_HUMAN32.320.3
RAF1_MOUSE32.318.8
Q59FA8_HUMAN32.119.1
ACVR1_HUMAN32.117.1
PAK1_CAEEL31.718
RAF1_HUMAN31.719.4
Q4VA93_MOUSE31.519.6
KPCD_MOUSE31.518.4
TGFR2_HUMAN3117.7
FGFR3_HUMAN3119.1
KPCB_RAT30.719.8
Q9Y6B5_HUMAN30.617.3
Q8LPE0_CHLRE30.519.6
Protein-Protein Interactions: