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Target Details

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Name:ATTR
Uniprot name:TTHY_HUMAN
Accession Numbers:P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:1BM7 1BMZ 1BZ8 1BZD 1BZE 1DVQ 1DVS 1DVT 1DVU 1DVX 1DVY 1DVZ 1E3F 1E4H 1E5A 1ETA 1ETB 1F41 1F64 1F86 1FH2 1FHN 1G1O 1GKO 1ICT 1III 1IIK 1IJN 1QAB 1QWH 1RLB 1SOK 1SOQ 1THA 1THC 1TLM 1TSH 1TT6 1TTA 1TTB 1TTC 1TTR 1TYR 1TZ8 1U21 1X7S 1X7T 1Y1D 1Z7J 1ZCR 1ZD6 2B14 2B15 2B16 2B77 2B9A 2F7I 2F8I 2FBR 2FLM 2G3X 2G3Z 2G4E 2G4G 2G5U 2G9K 2GAB 2H4E 2NOY 2PAB 2QEL 2QGB 2QGC 2QGD 2QGE 2ROX 2ROY 2TRH 2TRY 3B56 3BSZ 3BT0 3CBR 3CFM 3CFN 3CFQ 3CFT 3CN0 3CN1 3CN2 3CN3 3CN4 3CXF 3CYK 3D2T 3D7P 3DGD 3DID 3DJR 3DJS 3DJT 3DJZ 3DK0 3DK2 3DO4 3ESN 3ESO 3ESP 3FC8 3FCB 3GLZ 3GS0 3GS4 3GS7 5TTR
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
(3E)-3-[(4-Methoxyphenyl)imino]-1,3-dihydro-2H-indol-2-one489554BindingDB-show
1-Naphthylamine-5-sulfonic acid6793BindingDB-show
2,6-Dimethyl-4-(2-phenylethenyl)phenol6365297BindingDB-show
2-(5-sulfanyl-1,3,4-oxadiazol-2-yl)phenol5712018BindingDB-show
2-[(3,5-dichloro-4-hydroxyperoxyphenyl)amino]benzoic acid4369477DrugBank-show
3',5'-DINITRO-N-ACETYL-L-THYRONINE449394DrugBank-show
3-(Phenylimino)oxindole36607BindingDB-show
AC1LBBIA554870BindingDB-show
AC1LGA86817932BindingDB-show
AC1MDSBZ2816035BindingDB-show
AC1N85QI4313553BindingDB-show
AC1PMXC29250879BindingDB-show
AE-562/122221731822412BindingDB-show
Alitretinoin444795SuperTarget-show
ALITRETINOIN449171SuperTarget-show
Anilinonaphthalenesulfonic acid1369BindingDB-show
CBDivE_0025525007291BindingDB-show
CHEMBL23859044436911BindingDB-show
CHEMBL24080523656591BindingDB-show
CHEMBL24080623656595BindingDB-show
CHEMBL24080723656592BindingDB-show
CHEMBL24102523656754BindingDB-show
CHEMBL24145318433807BindingDB-show
CHEMBL24145422133420BindingDB-show
CHEMBL39287244436910BindingDB-show
CHEMBL39287344436913BindingDB-show
CHEMBL43849823656596BindingDB-show
CHEMBL57159745485457BindingDB-show
CHEMBL57181319646873BindingDB-show
CHEMBL57222445485453BindingDB-show
CHEMBL57611145485426BindingDB-show
Cloxifenolum5564BindingDB-show
Dextrothyroxinum8730BindingDB-show
Dextrothyroxinum8730SuperTarget-show
Diaethylstilboestrolum448537SuperTarget-show
DIBENZOFURAN-4,6-DICARBOXYLIC ACID3022DrugBank-show
Dichlofenac3033DrugBank-show
Dichlofenac3033SuperTarget-show
Diethylstilboesterol3054DrugBank-show
Diflunisal3059DrugBank-show
Essigsaeure176DrugBank-show
Flufenaminsaeure3371DrugBank-show
Flufenaminsaeure3371SuperTargetPMID 15080795show
FLURBIPROFEN3394SuperTarget-show
FT123656594BindingDB-show
isotretinoino5282379SuperTarget-show
Methylsulfinylmethane679DrugBank-show
Methylsulfinylmethane679SuperTarget-show
Milrinone4197SuperTarget-show
Monothioethyleneglycol1567DrugBank-show
N-(M-TRIFLUOROMETHYLPHENYL) PHENOXAZINE-4,6-DICARBOXYLIC ACID4310DrugBank-show
N-Methylisatin16358BindingDB-show
nchembio.281-comp144472866BindingDB-show
nchembio.281-comp244472868BindingDB-show
nchembio.281-comp344472865BindingDB-show
nchembio.281-comp444472863BindingDB-show
nchembio.281-comp814771920BindingDB-show
NSC201446304752BindingDB-show
NSC298520326728BindingDB-show
O-TRIFLUOROMETHYLPHENYL ANTHRANILIC ACID445155DrugBank-show
Oprea1_05543111218587BindingDB-show
Oprea1_08478824046234BindingDB-show
Oprea1_17058724020163BindingDB-show
Oprea1_23885623912193BindingDB-show
Pentabromophenol11852DrugBank-show
Pseudoisatin7054BindingDB-show
Resveratrol445154DrugBank-show
Retinol1071SuperTarget-show
STK644738659923BindingDB-show
tetraiodothyroacetate65552DrugBank-show
Tetraiodothyronine5819BindingDB-show
Tetraiodothyronine5819DrugBank-show
Tetraiodothyronine853DrugBank-show
Tribromophenol1483DrugBank-show
Triclosan derivative, 723656593BindingDB-show
Trihydroxypropane753SuperTarget-show
Triiodothyronine5920DrugBank-show
Triiodothyronine23666110DrugBank-show
Triiodothyronine861DrugBank-show
WLN: QR BI DI FI11862BindingDB-show
ZINC00066358617284BindingDB-show
ZINC04697734630604BindingDB-show
Synonyms:
ATTR
Prealbumin
TBPA
Transthyretin
TTR
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
TTHY_RAT91.882.3
Q9PTT3_SPAAU66.249.4
CYTC_HUMAN38.621.6
Q8WRW5_APIME36.421.8
Q5T1J1_HUMAN35.621.2
CYC2_RHOVI35.620.2
HUTP_BACSU34.321.7
C562_ECOLX3417.3
VIP_HUMAN33.918.2
REG1A_HUMAN33.916.9
Q8WW80_HUMAN33.517.9
Q6IRV8_HUMAN33.517.9
Q97YX6_SULSO33.318.2
ALL2_DERFA32.722.6
AZR_BACSU32.521.5
SHP_RHOS432.117.3
C556_RHOPA31.917.3
TRHN1_CHLMO31.818.8
Q9H2M2_HUMAN31.621.3
Q820S6_NITEU31.419.8
IL2_HYLLA31.315.4
TXVE_VIPAA31.319.2
Q81F54_BACCR31.115.8
ERV2_YEAST31.121.4
FLAV_SYNE73115
FGF1_BOVIN30.816.5
CPD_ARATH30.715.3
RISB_MYCTU30.618.7
SAT2_HUMAN30.617.9
GLBF1_EPTBU30.612.6
Protein-Protein Interactions: