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Target Details

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Name:Cachectin
Uniprot name:TNFA_HUMAN
Accession Numbers:O43647 P01375 Q9P1Q2 Q9UIV3
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:1A8M 1TNF 2AZ5 2E7A 2TUN 2ZJC 2ZPX 4TSV 5TSW
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-methyl-8-sulfanylidene-7,9-dihydropurine-2,6-dione3081830BindingDB-show
AC1LA4PI461663BindingDB-show
AC1LA4PO461665BindingDB-show
AC1LA4PR461666BindingDB-show
Adenyldeoxyriboside60961DrugBank-show
Adenyldeoxyriboside13730DrugBank-show
AIDS029875461664BindingDB-show
Atorvastatin60823DrugBank-show
BAS 00390300676987BindingDB-show
CHEBI:400836914621BindingDB-show
CHEBI:64707244350352BindingDB-show
CHEBI:64710044350368BindingDB-show
CHEBI:65222244350458BindingDB-show
CHEMBL10871010503011BindingDB-show
CHEMBL10926410694592BindingDB-show
CHEMBL1101109840925BindingDB-show
CHEMBL11042110452587BindingDB-show
CHEMBL11094910573618BindingDB-show
CHEMBL11095610812014BindingDB-show
CHEMBL1109729797095BindingDB-show
CHEMBL11111110836140BindingDB-show
CHEMBL11150310619896BindingDB-show
CHEMBL11154410765443BindingDB-show
CHEMBL11156010571036BindingDB-show
CHEMBL1116379840218BindingDB-show
CHEMBL1119739949152BindingDB-show
CHEMBL11344210572133BindingDB-show
CHEMBL12445610756895BindingDB-show
CHEMBL12474310539258BindingDB-show
CHEMBL12497510547110BindingDB-show
CHEMBL12552210553070BindingDB-show
CHEMBL12563210759371BindingDB-show
CHEMBL12567410548866BindingDB-show
CHEMBL12568711792503BindingDB-show
CHEMBL12578710498658BindingDB-show
CHEMBL12624610736217BindingDB-show
CHEMBL12624910665860BindingDB-show
CHEMBL12628310806631BindingDB-show
CHEMBL12635310683932BindingDB-show
CHEMBL12641510762006BindingDB-show
CHEMBL12643410591397BindingDB-show
CHEMBL12645010732591BindingDB-show
CHEMBL12651110685991BindingDB-show
CHEMBL12664610740359BindingDB-show
CHEMBL12680510787769BindingDB-show
CHEMBL12680610498936BindingDB-show
CHEMBL12681610636108BindingDB-show
CHEMBL12681710423517BindingDB-show
CHEMBL12686710826387BindingDB-show
CHEMBL12691210803497BindingDB-show
CHEMBL12694510831571BindingDB-show
CHEMBL12700310640389BindingDB-show
CHEMBL1270429948975BindingDB-show
CHEMBL12708110541869BindingDB-show
CHEMBL12714410515426BindingDB-show
CHEMBL12714810735519BindingDB-show
CHEMBL12714910808807BindingDB-show
CHEMBL12715410838771BindingDB-show
CHEMBL12719210613843BindingDB-show
CHEMBL12719810522445BindingDB-show
CHEMBL12725910734444BindingDB-show
CHEMBL12728010547590BindingDB-show
CHEMBL12729110780887BindingDB-show
CHEMBL12739010570570BindingDB-show
CHEMBL12746610733368BindingDB-show
CHEMBL12747810522585BindingDB-show
CHEMBL12798910854252BindingDB-show
CHEMBL12799010538504BindingDB-show
CHEMBL12895210500152BindingDB-show
CHEMBL12979210688432BindingDB-show
CHEMBL14835111729454BindingDB-show
CHEMBL16923910779971BindingDB-show
CHEMBL16979510595485BindingDB-show
CHEMBL16988210515726BindingDB-show
CHEMBL17025910692755BindingDB-show
CHEMBL17026744382442BindingDB-show
CHEMBL17039510546983BindingDB-show
CHEMBL1704799904193BindingDB-show
CHEMBL17085510663883BindingDB-show
CHEMBL17092010688147BindingDB-show
CHEMBL17117910712721BindingDB-show
CHEMBL17127210831577BindingDB-show
CHEMBL17140610660380BindingDB-show
CHEMBL17198910019033BindingDB-show
CHEMBL17222410661296BindingDB-show
CHEMBL17261910737740BindingDB-show
CHEMBL17266910852312BindingDB-show
CHEMBL17425310755908BindingDB-show
CHEMBL17425410731615BindingDB-show
CHEMBL18230644394994BindingDB-show
CHEMBL18347444394916BindingDB-show
CHEMBL18399544394426BindingDB-show
CHEMBL18650044395271BindingDB-show
CHEMBL18666344395157BindingDB-show
CHEMBL18674344396048BindingDB-show
CHEMBL18709244395506BindingDB-show
CHEMBL18714144395454BindingDB-show
CHEMBL18724544395030BindingDB-show
CHEMBL18747444396001BindingDB-show
CHEMBL18785244395069BindingDB-show
CHEMBL26348010590173BindingDB-show
CHEMBL3203479907022BindingDB-show
CHEMBL32103210687089BindingDB-show
CHEMBL32255310091288BindingDB-show
CHEMBL32281410669458BindingDB-show
CHEMBL3230099841064BindingDB-show
CHEMBL32708310764262BindingDB-show
CHEMBL33333310827468BindingDB-show
CHEMBL33834010713603BindingDB-show
CHEMBL33876510639329BindingDB-show
CHEMBL33995210685254BindingDB-show
CHEMBL34009710543322BindingDB-show
CHEMBL34034610708682BindingDB-show
CHEMBL34082710731271BindingDB-show
CHEMBL34101210527621BindingDB-show
CHEMBL34109610713794BindingDB-show
CHEMBL34207611824787BindingDB-show
CHEMBL35272510520713BindingDB-show
CHEMBL35425744382351BindingDB-show
CHEMBL35426310782487BindingDB-show
CHEMBL35504244383341BindingDB-show
CHEMBL35543310539960BindingDB-show
CHEMBL36085444395660BindingDB-show
CHEMBL36312644395434BindingDB-show
CHEMBL36524744395643BindingDB-show
CHEMBL36845810758494BindingDB-show
CHEMBL36851510730172BindingDB-show
CHEMBL36911544394819BindingDB-show
CHEMBL41424310594315BindingDB-show
CHEMBL41442910736883BindingDB-show
CHEMBL41883610694297BindingDB-show
CHEMBL41920410570106BindingDB-show
CHEMBL41977510686085BindingDB-show
CHEMBL42360944382640BindingDB-show
CHEMBL42697544395269BindingDB-show
CHEMBL43501410850191BindingDB-show
CHEMBL43607144363884BindingDB-show
CHEMBL43627744395976BindingDB-show
CHEMBL44669744395935BindingDB-show
Chitosamine439213DrugBank-show
Chloroquinium2719DrugBank-show
CID 98466769846676BindingDB-show
Contraspasmin2783DrugBank-show
Cordemcura3698DrugBank-show
Cordemcura3698SuperTargetPMID 9473138show
CP Dmx II151419BindingDB-show
Dimethyloxohexylxanthine4740BindingDB-show
Flupirtine53276SuperTargetPMID 11080178show
N-Cyclopropylmethylnoroxymorphone5360515DrugBank-show
NSC231573428211BindingDB-show
Oprea1_48360810360825BindingDB-show
Pranlukast115100DrugBank-show
Procaterol688561DrugBank-show
RO 20-17245087BindingDB-show
ROLIPRAM5092BindingDB-show
SAQUINAVIR60787DrugBank-show
SIMVASTATIN54454DrugBank-show
Tetrafluorothalidomide467265BindingDB-show
Theophilcholine5426DrugBank-show
Theophilcholine5426SuperTargetPMID 17047296show
Synonyms:
Cachectin
TNF-a
TNF-alpha
Tumor necrosis factor
Tumor necrosis factor ligand superfamily member 2
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
TNFA_MOUSE89.478.8
TNFC_HUMAN40.125
CD40L_HUMAN34.823.3
DEF_THETH34.420.6
SUHB_METJA33.917.5
ISPD_THEMA33.720.6
BACR_HALSA33.119.5
O43211_HUMAN32.820.9
PNPP_YEAST32.218.2
Q9HFV6_MAGGR32.217.9
RRF_THEMA32.216.7
ACT3_STRCO32.121.8
Q8WYK3_HUMAN31.819.6
Q6TZ08_HUMAN31.617.3
Y1034_HAEIN31.515.9
UPP_THEMA31.317.1
ARGB_ECOLI31.316
SAR1B_CRIGR31.118.3
Q8WYK4_HUMAN3118.8
LIVG_METJA30.915.5
KITH_UREPA30.617.7
O57975_PYRHO30.514.9
CTDS1_MOUSE30.314.7
UCRI_BOVIN30.316.2
KAD1_YEAST30.216.4
PSPC_HUMAN30.117.8
Q9RA47_THETH30.117.8
NANA_SHIFL3018.6
GCH1_HUMAN3014.8
SC11A_HUMAN3016.7
Protein-Protein Interactions: