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Target Details

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Name:c-erbA-1
Uniprot name:THA_HUMAN
Accession Numbers:A8K3B5 P10827 P21205 Q8N6A1 Q96H73
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:1NAV 2H79
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2-[3,5-dibromo-4-[4-hydroxy-3-(phenethylcarbamoyl)phenoxy]phenyl]acetic656928BindingDB-show
3,5,3'-triiodothyronine7048703BindingDB-show
3,5-Dimethyl-3'-isopropylthyronine108112BindingDB-show
4-hydroxy thyromimetic, 13a23648122BindingDB-show
4-hydroxy thyromimetic, 13b23648123BindingDB-show
4-hydroxy thyromimetic, 13c23648124BindingDB-show
4-hydroxy thyromimetic, 13d23648125BindingDB-show
4-hydroxy thyromimetic, 13e23648126BindingDB-show
4-hydroxy thyromimetic, 13f23648127BindingDB-show
4-hydroxy thyromimetic, 13g23648128BindingDB-show
4-hydroxy thyromimetic, 13h23648129BindingDB-show
4-hydroxy thyromimetic, 15a23648130BindingDB-show
4-hydroxy thyromimetic, 15b23648131BindingDB-show
4-hydroxy thyromimetic, 15d23648132BindingDB-show
4-hydroxy thyromimetic, 15e23648133BindingDB-show
4-hydroxy thyromimetic, 15f23648134BindingDB-show
4-hydroxy thyromimetic, 15g23648135BindingDB-show
4-hydroxy thyromimetic, 15h23648136BindingDB-show
4-hydroxy thyromimetic, 15i23648137BindingDB-show
4-hydroxy thyromimetic, 15j23648138BindingDB-show
4-hydroxy thyromimetic, 1623648139BindingDB-show
4-hydroxy thyromimetic, 9a23648105BindingDB-show
4-hydroxy thyromimetic, 9b23648106BindingDB-show
4-hydroxy thyromimetic, 9c23648107BindingDB-show
4-hydroxy thyromimetic, 9d23648108BindingDB-show
4-hydroxy thyromimetic, 9f23648109BindingDB-show
4-hydroxy thyromimetic, 9g23648110BindingDB-show
4-hydroxy thyromimetic, 9h23648111BindingDB-show
4-hydroxy thyromimetic, 9i23648112BindingDB-show
4-hydroxy thyromimetic, 9j23648113BindingDB-show
4-hydroxy thyromimetic, 9k23648114BindingDB-show
4-hydroxy thyromimetic, 9l23648115BindingDB-show
4-hydroxy thyromimetic, 9m23648116BindingDB-show
4-hydroxy thyromimetic, 9n23648117BindingDB-show
4-hydroxy thyromimetic, 9o23648118BindingDB-show
4-hydroxy thyromimetic, 9p23648119BindingDB-show
4-hydroxy thyromimetic, 9q23644731BindingDB-show
4-hydroxy thyromimetic, 9r23648120BindingDB-show
4-hydroxy thyromimetic, 9s23648121BindingDB-show
AC1L2WTA79170BindingDB-show
Amiodarone Hydrochloride2157BindingDB-show
benzyl derivative, 11a23648093BindingDB-show
benzyl derivative, 11b10113366BindingDB-show
benzyl derivative, 11c10137392BindingDB-show
benzyl derivative, 11d23648094BindingDB-show
benzyl derivative, 11e23648095BindingDB-show
benzyl derivative, 11f16730429BindingDB-show
benzyl derivative, 1310202877BindingDB-show
benzyl derivative, 149825337BindingDB-show
benzyl derivative, 1523648096BindingDB-show
benzyl derivative, 823648092BindingDB-show
CHEMBL10943010413582BindingDB-show
CHEMBL11015810252856BindingDB-show
CHEMBL11033510936773BindingDB-show
CHEMBL1119539980009BindingDB-show
CHEMBL120910924748569BindingDB-show
CHEMBL120917049862248BindingDB-show
CHEMBL120917344476535BindingDB-show
CHEMBL12420522339458BindingDB-show
CHEMBL1252429847869BindingDB-show
CHEMBL12594644349576BindingDB-show
CHEMBL16070310897325BindingDB-show
CHEMBL16088310918755BindingDB-show
CHEMBL18081944391371BindingDB-show
CHEMBL18095244391387BindingDB-show
CHEMBL18233944391353BindingDB-show
CHEMBL18243010224506BindingDB-show
CHEMBL18273510161481BindingDB-show
CHEMBL18300044391338BindingDB-show
CHEMBL18305011452211BindingDB-show
CHEMBL18305710109471BindingDB-show
CHEMBL18312244391411BindingDB-show
CHEMBL18317010298167BindingDB-show
CHEMBL18317611677766BindingDB-show
CHEMBL18356515540528BindingDB-show
CHEMBL18372744391396BindingDB-show
CHEMBL18382944391409BindingDB-show
CHEMBL1838519910192BindingDB-show
CHEMBL18386344391349BindingDB-show
CHEMBL19214210135986BindingDB-show
CHEMBL19234611209929BindingDB-show
CHEMBL19242611281247BindingDB-show
CHEMBL1924909925361BindingDB-show
CHEMBL19250811164881BindingDB-show
CHEMBL19263911153607BindingDB-show
CHEMBL19315211291923BindingDB-show
CHEMBL19361544403627BindingDB-show
CHEMBL19385144403605BindingDB-show
CHEMBL1938649980722BindingDB-show
CHEMBL19424210479778BindingDB-show
CHEMBL19507910455127BindingDB-show
CHEMBL19532744403607BindingDB-show
CHEMBL19555611350323BindingDB-show
CHEMBL19585511395277BindingDB-show
CHEMBL19661344403628BindingDB-show
CHEMBL19664244403634BindingDB-show
CHEMBL19836710456672BindingDB-show
CHEMBL19887510049652BindingDB-show
CHEMBL20233623648104BindingDB-show
CHEMBL20252110297431BindingDB-show
CHEMBL2029409933993BindingDB-show
CHEMBL20355544408427BindingDB-show
CHEMBL2037779951790BindingDB-show
CHEMBL20382844408544BindingDB-show
CHEMBL20460910299993BindingDB-show
CHEMBL20517123648103BindingDB-show
CHEMBL23608023648080BindingDB-show
CHEMBL23628923648083BindingDB-show
CHEMBL23629023648085BindingDB-show
CHEMBL23629123648086BindingDB-show
CHEMBL23649910030727BindingDB-show
CHEMBL23650023648090BindingDB-show
CHEMBL25088044445727BindingDB-show
CHEMBL25143944445731BindingDB-show
CHEMBL25145623648101BindingDB-show
CHEMBL26363044452442BindingDB-show
CHEMBL26394244396331BindingDB-show
CHEMBL26452744328257BindingDB-show
CHEMBL26693544396297BindingDB-show
CHEMBL28934310456830BindingDB-show
CHEMBL3181329938222BindingDB-show
CHEMBL32236110936298BindingDB-show
CHEMBL35964744391408BindingDB-show
CHEMBL36013744391337BindingDB-show
CHEMBL36077411455692BindingDB-show
CHEMBL3611629803551BindingDB-show
CHEMBL36436844396296BindingDB-show
CHEMBL37124544403606BindingDB-show
CHEMBL37242810457976BindingDB-show
CHEMBL37859344408607BindingDB-show
CHEMBL38193723648102BindingDB-show
CHEMBL38497544396284BindingDB-show
CHEMBL39136723648081BindingDB-show
CHEMBL39151223648084BindingDB-show
CHEMBL39151323648087BindingDB-show
CHEMBL391749933119BindingDB-show
CHEMBL39320123648089BindingDB-show
CHEMBL40767244396317BindingDB-show
CHEMBL40837644396283BindingDB-show
CHEMBL41118544396272BindingDB-show
CHEMBL4131423648079BindingDB-show
CHEMBL41425244396252BindingDB-show
CHEMBL41431844396316BindingDB-show
CHEMBL41562144396251BindingDB-show
CHEMBL41843210904700BindingDB-show
CHEMBL41901610246057BindingDB-show
CHEMBL42536611463526BindingDB-show
CHEMBL42593910479779BindingDB-show
CHEMBL42756844396282BindingDB-show
CHEMBL43685944396271BindingDB-show
CHEMBL44097523648082BindingDB-show
CHEMBL44737825150127BindingDB-show
CHEMBL44859515942131BindingDB-show
CHEMBL45752715941997BindingDB-show
CHEMBL45752825150424BindingDB-show
CHEMBL45752925149598BindingDB-show
CHEMBL45878415940421BindingDB-show
CHEMBL45914825149230BindingDB-show
CHEMBL48031244567764BindingDB-show
CHEMBL48031324894049BindingDB-show
CHEMBL48575815942413BindingDB-show
CHEMBL48592725150124BindingDB-show
CHEMBL48592825149503BindingDB-show
CHEMBL48593925149504BindingDB-show
CHEMBL48615825150225BindingDB-show
CHEMBL48635825149592BindingDB-show
CHEMBL48635911999781BindingDB-show
CHEMBL50087515941850BindingDB-show
CHEMBL50508415941849BindingDB-show
CHEMBL51186211999783BindingDB-show
CHEMBL51238325150325BindingDB-show
CHEMBL51633015941998BindingDB-show
CHEMBL51921544589465BindingDB-show
CHEMBL51972118415120BindingDB-show
CHEMBL52085725149505BindingDB-show
CHEMBL53815044186475BindingDB-show
CHEMBL53913944186301BindingDB-show
CHEMBL53939344186034BindingDB-show
CHEMBL54022744186299BindingDB-show
CHEMBL54122744186298BindingDB-show
CHEMBL54948244186171BindingDB-show
CHEMBL54948344186471BindingDB-show
CHEMBL54955744186168BindingDB-show
CHEMBL54968544186175BindingDB-show
CHEMBL55009444186236BindingDB-show
CHEMBL55076544186234BindingDB-show
CHEMBL55076644186476BindingDB-show
CHEMBL55084144186520BindingDB-show
CHEMBL55084544186173BindingDB-show
CHEMBL55104644186521BindingDB-show
CHEMBL55118444186097BindingDB-show
CHEMBL55118544186098BindingDB-show
CHEMBL55124445270610BindingDB-show
CHEMBL55145044186519BindingDB-show
CHEMBL55171044186032BindingDB-show
CHEMBL55179144186424BindingDB-show
CHEMBL55197944186422BindingDB-show
CHEMBL55210544186099BindingDB-show
CHEMBL55210644186421BindingDB-show
CHEMBL55215844186101BindingDB-show
CHEMBL55218544186474BindingDB-show
CHEMBL55239244186517BindingDB-show
CHEMBL55274244186100BindingDB-show
CHEMBL55319044186523BindingDB-show
CHEMBL55365244186237BindingDB-show
CHEMBL55572644186305BindingDB-show
CHEMBL55574944186235BindingDB-show
CHEMBL55790544186469BindingDB-show
CHEMBL55810644186170BindingDB-show
CHEMBL55810744186470BindingDB-show
CHEMBL55888944186562BindingDB-show
CHEMBL55952044186035BindingDB-show
CHEMBL55971644186103BindingDB-show
CHEMBL56011444186172BindingDB-show
CHEMBL56014844186033BindingDB-show
CHEMBL56030944186300BindingDB-show
CHEMBL56031044186302BindingDB-show
CHEMBL56031144186472BindingDB-show
CHEMBL56051044186303BindingDB-show
CHEMBL56051244186473BindingDB-show
CHEMBL56067544186563BindingDB-show
CHEMBL56091144186518BindingDB-show
CHEMBL56097244186169BindingDB-show
CHEMBL56105044186104BindingDB-show
CHEMBL56124524843916BindingDB-show
CHEMBL56164844186304BindingDB-show
CHEMBL56165344186232BindingDB-show
CHEMBL56185021653696BindingDB-show
CHEMBL56225044186238BindingDB-show
CHEMBL56318144186102BindingDB-show
CHEMBL56336844186239BindingDB-show
CHEMBL56515044186425BindingDB-show
CHEMBL57030744186233BindingDB-show
CHEMBL57234844186423BindingDB-show
CHEMBL59402410322653BindingDB-show
CHEMBL59402510274474BindingDB-show
CHEMBL59404710276774BindingDB-show
CHEMBL59635010279835BindingDB-show
CHEMBL6089909819350BindingDB-show
CHEMBL8382923648097BindingDB-show
CHEMBL8395323648098BindingDB-show
CHEMBL8627123648099BindingDB-show
CHEMBL9718744328280BindingDB-show
CHEMBL976139799416BindingDB-show
CHEMBL981359908218BindingDB-show
CID 1594200511998611BindingDB-show
CO2250997754BindingDB-show
cyclohexyl derivative, 711247142BindingDB-show
Detrothyronine71212BindingDB-show
dibromo benzoic acid, 79932398BindingDB-show
dichloro benzoic acid, 11b9862799BindingDB-show
KB-1419863447BindingDB-show
KM-0738523648100BindingDB-show
LS-117889872203BindingDB-show
MB-0734415941848BindingDB-show
Mifepristone55245BindingDB-show
N-acylated-alpha-amino acid derivative, 4b23648088BindingDB-show
N-[3,5-dimethyl-4-(4'-hydroxy-3'-isopropylphenoxy)-phenyl]-oxamic acid9874938BindingDB-show
Sobetirome9862248BindingDB-show
STK0618864266779BindingDB-show
Tetraiodothyronine5819DrugBank-show
Tetraiodothyronine853DrugBank-show
thyromimetic, 49869395BindingDB-show
thyromimetic, 5a10321482BindingDB-show
thyromimetic, 5b10027822BindingDB-show
thyromimetic, 623648091BindingDB-show
THYROPROPIC ACID5804BindingDB-show
Triiodothyroacetic acid5803BindingDB-show
Triiodothyronine5920BindingDB-show
Triiodothyronine5920DrugBank-show
Triiodothyronine23666110DrugBank-show
Triiodothyronine861DrugBank-show
ZINC029006182249170BindingDB-show
Synonyms:
c-erbA-1
C-erbA-alpha
EAR-7
EAR7
Nuclear receptor subfamily 1 group A member 1
Thyroid hormone receptor alpha
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
THA_SHEEP78.977
THB_HUMAN60.652.2
B6ZGR8_HUMAN44.428.7
RARB_HUMAN41.827.7
RARG_HUMAN41.627.7
Q86UC5_HUMAN40.726.1
RARB_MOUSE39.627.1
Q6FHY0_HUMAN38.724.4
Q5QHG3_HUMAN38.724.4
RORA_MOUSE37.824.8
HNF4A_RAT37.822.9
HNF4G_HUMAN36.823.1
NR1I3_MOUSE36.823.4
NR1H2_HUMAN36.623
NR1I2_MOUSE36.322.9
Q6I9R7_HUMAN35.824.8
RARA_HUMAN35.824.8
VDR_HUMAN35.821.7
PPARD_HUMAN35.721.8
NR1I2_HUMAN35.423
ERR1_HUMAN35.124.1
Q569H8_HUMAN35.124.1
NR1I3_HUMAN35.123.4
Q4U0F0_HUMAN34.923.4
VDR_RAT34.520.6
RXRA_MOUSE33.820.1
PPARA_HUMAN33.720.8
RXRA_HUMAN33.620.2
ERR3_HUMAN33.521.4
ERR3_MOUSE33.521.4
Protein-Protein Interactions: