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Target Details

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Name:Cytochrome P450 5A1
Uniprot name:THAS_RAT
Accession Numbers:P49430
EC-Number:5.3.99.5
Organism:Rat
Rattus norvegicus
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2-Ethyl-4-(3-pyridyl)-1(2H)-phthalazinone192280BindingDB-show
2-methyl-3-(4-(3-pyridinylmethyl)phenyl)-2-propenoic acid6437388PROMISCUOUSPMID 3161224show
2-Methyl-4-(5-thiazolyl)-1(2H)-phthalazinone192281BindingDB-show
3-((N-(Aminocarbonyl)-N-hydroxyamino)methyl)-6-phenoxychromene131820BindingDB-show
4,5-dibromo-N-(3-imidazol-1-ylpropyl)thiophene-2-carboxamide4834145BindingDB-show
4-[(1-cyclohexyl-2-imidazol-1-yl-ethylidene)amino]oxybutanoic Acid9971633BindingDB-show
4-[(1-cyclohexyl-2-imidazol-1-yl-ethylidene)amino]oxybutanoic Acid10424476BindingDB-show
5-(1-imidazol-1-yloctan-2-ylideneamino)oxypentanoic Acid10448061BindingDB-show
5-(1-imidazol-1-yloctan-2-ylideneamino)oxypentanoic Acid10018213BindingDB-show
5-[(1-cyclohexyl-2-imidazol-1-yl-ethylidene)amino]oxypentanoic Acid10244703BindingDB-show
5-[(1-cyclohexyl-2-imidazol-1-yl-ethylidene)amino]oxypentanoic Acid10244704BindingDB-show
5-[(2-imidazol-1-yl-1-phenyl-ethylidene)amino]oxypentanoic Acid10402603BindingDB-show
5-[(2-imidazol-1-yl-1-phenyl-ethylidene)amino]oxypentanoic Acid10402602BindingDB-show
5-[(2-imidazol-1-yl-1-phenyl-propylidene)amino]oxypentanoic Acid9973005BindingDB-show
5-[(2-imidazol-1-yl-1-phenyl-propylidene)amino]oxypentanoic Acid10018589BindingDB-show
6-Hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole443292BindingDB-show
6-Hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole443292PROMISCUOUSPMID 12023941show
AC1MH2UX2970607BindingDB-show
AC1MISG53078928BindingDB-show
AC1NJTGY4877443BindingDB-show
AC1NX7ZH5747298BindingDB-show
BAS 056025963152639BindingDB-show
CGS 24891195771BindingDB-show
CHEBI:64637844332048BindingDB-show
CHEBI:64639944334662BindingDB-show
CHEBI:64640044334909BindingDB-show
CHEBI:64651544334661BindingDB-show
CHEBI:64652144334866BindingDB-show
CHEBI:64653944334911BindingDB-show
CHEBI:64656944334701BindingDB-show
CHEBI:64864744380051BindingDB-show
CHEBI:64867444379972BindingDB-show
CHEBI:65131144312884BindingDB-show
CHEBI:65146044312885BindingDB-show
CHEBI:65159344334892BindingDB-show
CHEBI:65179644334700BindingDB-show
CHEMBL10060710069259BindingDB-show
CHEMBL10067111725497BindingDB-show
CHEMBL10078010052197BindingDB-show
CHEMBL10123410406649BindingDB-show
CHEMBL10172310341287BindingDB-show
CHEMBL10186110049991BindingDB-show
CHEMBL10194210098355BindingDB-show
CHEMBL10215610454981BindingDB-show
CHEMBL10224310063338BindingDB-show
CHEMBL10334810070199BindingDB-show
CHEMBL10365610454184BindingDB-show
CHEMBL10415610042219BindingDB-show
CHEMBL10538610335738BindingDB-show
CHEMBL10558710425738BindingDB-show
CHEMBL11442410412393BindingDB-show
CHEMBL11475110094462BindingDB-show
CHEMBL11812410431401BindingDB-show
CHEMBL11818410430550BindingDB-show
CHEMBL11818810092922BindingDB-show
CHEMBL11856810024132BindingDB-show
CHEMBL11966110320883BindingDB-show
CHEMBL12001910250339BindingDB-show
CHEMBL12016510340286BindingDB-show
CHEMBL12020710341794BindingDB-show
CHEMBL1202289978202BindingDB-show
CHEMBL12024910367685BindingDB-show
CHEMBL1202509801735BindingDB-show
CHEMBL12025910023102BindingDB-show
CHEMBL12028410431402BindingDB-show
CHEMBL12037010380987BindingDB-show
CHEMBL12037210016908BindingDB-show
CHEMBL12049610455115BindingDB-show
CHEMBL12081110409839BindingDB-show
CHEMBL12094310453182BindingDB-show
CHEMBL12104310251833BindingDB-show
CHEMBL12126144346027BindingDB-show
CHEMBL12128910050347BindingDB-show
CHEMBL12130410344641BindingDB-show
CHEMBL12131411723604BindingDB-show
CHEMBL1220089931330BindingDB-show
CHEMBL1221239865257BindingDB-show
CHEMBL12247210364364BindingDB-show
CHEMBL12330710342027BindingDB-show
CHEMBL14718313588925BindingDB-show
CHEMBL14741313588952BindingDB-show
CHEMBL14892813588953BindingDB-show
CHEMBL15173213588944BindingDB-show
CHEMBL16564813588980BindingDB-show
CHEMBL16599713588978BindingDB-show
CHEMBL16642513290795BindingDB-show
CHEMBL16673113588977BindingDB-show
CHEMBL16683413580028BindingDB-show
CHEMBL16737213580026BindingDB-show
CHEMBL2394214071622BindingDB-show
CHEMBL26797813752980BindingDB-show
CHEMBL26864520257587BindingDB-show
CHEMBL27525610096033BindingDB-show
CHEMBL29672010095579BindingDB-show
CHEMBL30738213952787BindingDB-show
CHEMBL30741213952837BindingDB-show
CHEMBL30763113952803BindingDB-show
CHEMBL30772513952797BindingDB-show
CHEMBL30836013952848BindingDB-show
CHEMBL30855013952845BindingDB-show
CHEMBL30996013952779BindingDB-show
CHEMBL31090413952795BindingDB-show
CHEMBL31095513952784BindingDB-show
CHEMBL31168913952745BindingDB-show
CHEMBL31253613952771BindingDB-show
CHEMBL31834210475789BindingDB-show
CHEMBL31999310429927BindingDB-show
CHEMBL32038844331871BindingDB-show
CHEMBL32039410334136BindingDB-show
CHEMBL32135810313997BindingDB-show
CHEMBL32201510246235BindingDB-show
CHEMBL32309510429032BindingDB-show
CHEMBL32309610386798BindingDB-show
CHEMBL32436410480363BindingDB-show
CHEMBL32652110386455BindingDB-show
CHEMBL33083710087973BindingDB-show
CHEMBL33121810071192BindingDB-show
CHEMBL33135610389298BindingDB-show
CHEMBL33323610454526BindingDB-show
CHEMBL33323710251282BindingDB-show
CHEMBL3387419930816BindingDB-show
CHEMBL33987710365109BindingDB-show
CHEMBL34531013588913BindingDB-show
CHEMBL35480813588982BindingDB-show
CHEMBL35561413588984BindingDB-show
CHEMBL35592913588950BindingDB-show
CHEMBL3587779884086BindingDB-show
CHEMBL40669313752983BindingDB-show
CHEMBL41760313371094BindingDB-show
CHEMBL42028111723348BindingDB-show
CHEMBL42093113952800BindingDB-show
CHEMBL43978710073846BindingDB-show
CHEMBL7207013952816BindingDB-show
CHEMBL7227313952833BindingDB-show
CHEMBL7238213952798BindingDB-show
CHEMBL7245013952778BindingDB-show
CHEMBL7268413952781BindingDB-show
CHEMBL7269013952796BindingDB-show
CHEMBL7292313952737BindingDB-show
CHEMBL7306513952773BindingDB-show
CHEMBL7314313952777BindingDB-show
CHEMBL7315813952791BindingDB-show
CHEMBL7323613952822BindingDB-show
CHEMBL7340713952839BindingDB-show
CHEMBL7342613952772BindingDB-show
CHEMBL7360613952824BindingDB-show
CHEMBL7362013952790BindingDB-show
CHEMBL7374813952823BindingDB-show
CHEMBL7376913952801BindingDB-show
CHEMBL7377913952774BindingDB-show
CHEMBL7385013952856BindingDB-show
CHEMBL7420713952805BindingDB-show
CHEMBL7451613952786BindingDB-show
CHEMBL7462713952793BindingDB-show
CHEMBL7469313952763BindingDB-show
CHEMBL7473313952782BindingDB-show
CHEMBL7482113952746BindingDB-show
CHEMBL7491513952761BindingDB-show
CHEMBL7497313952764BindingDB-show
CHEMBL7524913952850BindingDB-show
CHEMBL7525213952827BindingDB-show
CHEMBL7534413952794BindingDB-show
CHEMBL7544913952783BindingDB-show
CHEMBL7545113952799BindingDB-show
CHEMBL7560913952802BindingDB-show
CHEMBL7578713952776BindingDB-show
CHEMBL7623413952788BindingDB-show
CHEMBL7634113952785BindingDB-show
CHEMBL848920435302BindingDB-show
CHEMBL851513371096BindingDB-show
CHEMBL864813371092BindingDB-show
CHEMBL873520229525BindingDB-show
CHEMBL877813371093BindingDB-show
CHEMBL887013371082BindingDB-show
CHEMBL888713752979BindingDB-show
CHEMBL895713790021BindingDB-show
CHEMBL897620257589BindingDB-show
CHEMBL898613371091BindingDB-show
CHEMBL908813371095BindingDB-show
CHEMBL9861110252689BindingDB-show
Cifaop6366701BindingDB-show
DALTROBAN54343BindingDB-show
DAZMEGREL53555PROMISCUOUS3 PMIDsshow
DAZOXIBEN53001BindingDB-show
Dazoxiben hydrochloride53000PROMISCUOUS3 PMIDsshow
Diethyl 1,4-dihydro-2,6-dimethyl-4-(3-(1H-imidazol-1-yl)phenyl)-3,5-pyridinecarboxylate3076460BindingDB-show
Fce 272626366700BindingDB-show
Imitrodast65922BindingDB-show
Nifedipine Monohydrochloride4485BindingDB-show
ozagrel5282440BindingDB-show
Ridogrel5362391BindingDB-show
Ridogrel5362391PROMISCUOUS2 PMIDsshow
STK1696922952642BindingDB-show
STK2874212993632BindingDB-show
STK65853313952769BindingDB-show
SULOTROBAN51550BindingDB-show
ZILEUTON60490BindingDB-show
Synonyms:
Cytochrome P450 5A1
Thromboxane-A synthase
TXA synthase
TXS
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
THAS_MOUSE94.287.2
THAS_HUMAN89.379.7
CP3A5_HUMAN54.833.7
Q53GC3_HUMAN54.833.7
Q86SK3_HUMAN54.633.7
Q6GRK0_HUMAN54.433.3
CP3A4_HUMAN54.433.3
CP3A7_HUMAN54.433.5
CP3A2_RAT53.734.1
CP3A1_RAT53.333.8
CP343_HUMAN52.333.3
Q7Z448_HUMAN46.728.8
CP4F3_HUMAN42.426.3
CP4X1_HUMAN42.123.5
CP4B1_RAT4223.6
CP17A_HUMAN41.525.3
CP4FN_HUMAN41.321
CP4FC_HUMAN41.325
CP4A2_RAT41.323.4
CP4AB_HUMAN41.324
CP4Z1_HUMAN41.222.3
CP4FB_HUMAN4123.3
CP4F2_HUMAN40.825.7
CP2J2_HUMAN40.724.7
CP2C5_RABIT40.723.4
CP2AD_HUMAN40.622.7
Q6ZN67_HUMAN40.523.3
CP4F8_HUMAN40.423.9
CP4AE_RAT39.823.7
CP17A_RAT39.525.3
Protein-Protein Interactions:
No data available