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Target Details

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Name:TbetaR-II
Uniprot name:TGFR2_HUMAN
Accession Numbers:P37173 Q15580 Q6DKT6 Q99474
EC-Number:2.7.11.30
Organism:Homo sapiens
Human
PDB IDs:1KTZ 1M9Z 1PLO 2PJY
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL18629044396134BindingDB-show
CHEMBL20262510049774BindingDB-show
CHEMBL20273044408849BindingDB-show
CHEMBL2032149995838BindingDB-show
CHEMBL20361910361101BindingDB-show
CHEMBL20379144408807BindingDB-show
CHEMBL20406111507696BindingDB-show
CHEMBL20406311740079BindingDB-show
CHEMBL2041399972086BindingDB-show
CHEMBL20415810094943BindingDB-show
CHEMBL20417010064294BindingDB-show
CHEMBL20496610359218BindingDB-show
CHEMBL20623310002593BindingDB-show
CHEMBL36258811294864BindingDB-show
CHEMBL36281411316975BindingDB-show
CHEMBL36305811328863BindingDB-show
CHEMBL37771110321041BindingDB-show
CHEMBL3777179973794BindingDB-show
CHEMBL37816744408884BindingDB-show
CHEMBL38153210456042BindingDB-show
CHEMBL38283811723225BindingDB-show
CHEMBL4272119972935BindingDB-show
CHEMBL44117644408672BindingDB-show
CHEMBL49686223507055BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Kinome_368110029385BindingDB-show
Kinome_368211248978BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
TbetaR-I Inhibitor447966BindingDB-show
Trihydroxypropane753DrugBank-show
Trihydroxypropane753SuperTarget-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
TbetaR-II
TGF-beta receptor type II
TGF-beta receptor type-2
TGF-beta type II receptor
TGFR-2
Transforming growth factor-beta receptor type II
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
ACVR1_HUMAN44.127
TGFR1_RAT43.927.6
ACV1B_HUMAN4226.5
ACVL1_HUMAN39.325.5
AMHR2_HUMAN39.225.2
ATPB_RAT31.818.9
AKT1_MOUSE31.718.2
KPEL_DROME31.519.8
CP7A1_HUMAN31.417.6
KIF2C_MOUSE31.316.6
RAF1_HUMAN31.220.3
ZAP70_HUMAN3117.7
PAK1_CAEEL30.918.4
PGH1_MOUSE30.817.9
ARAF_HUMAN30.819.4
RAF1_RAT30.720
RAF1_MOUSE30.720
PGH1_RAT30.618
NRDD_BPT430.618.1
VDR_RAT30.117
PEN3_ADE023016.6
KPCB_HUMAN3016.5
MP2K7_HUMAN3017.3
Q26966_TRYCR3017.7
AIFM1_HUMAN3017.3
AKT1_HUMAN3018
Q4VA93_MOUSE29.916.8
ITK_HUMAN29.918.3
KPCA_BOVIN29.916.8
KPCA_HUMAN29.916.9
Protein-Protein Interactions: