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Target Details

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Name:p160 ROCK-1
Uniprot name:ROCK1_HUMAN
Accession Numbers:B0YJ91 Q13464 Q2KHM4 Q59GZ4
EC-Number:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1S1C 2ESM 2ETK 2ETR 2V55 3D9V
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE448043BindingDB-show
1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride4216BindingDB-show
AC1ME7UK2824220BindingDB-show
AC1NN7815038004BindingDB-show
Bio2_0004136610353BindingDB-show
CHEMBL107672122353185BindingDB-show
CHEMBL107767011615485BindingDB-show
CHEMBL107815510171832BindingDB-show
CHEMBL107824546883125BindingDB-show
CHEMBL107842610171595BindingDB-show
CHEMBL107842710171783BindingDB-show
CHEMBL107853746883122BindingDB-show
CHEMBL107853846883123BindingDB-show
CHEMBL107853946883124BindingDB-show
CHEMBL107882010125353BindingDB-show
CHEMBL107892910236371BindingDB-show
CHEMBL107903244622839BindingDB-show
CHEMBL107913546883168BindingDB-show
CHEMBL107924311492918BindingDB-show
CHEMBL107929310149184BindingDB-show
CHEMBL107929446883044BindingDB-show
CHEMBL107929546883045BindingDB-show
CHEMBL107992145375859BindingDB-show
CHEMBL108007144622840BindingDB-show
CHEMBL108007246883165BindingDB-show
CHEMBL108007346883166BindingDB-show
CHEMBL108024546883167BindingDB-show
CHEMBL108027944634494BindingDB-show
CHEMBL108090246865325BindingDB-show
CHEMBL108097046883169BindingDB-show
CHEMBL108099445375865BindingDB-show
CHEMBL108099545375866BindingDB-show
CHEMBL108119646879806BindingDB-show
CHEMBL108206111694317BindingDB-show
CHEMBL108243946889406BindingDB-show
CHEMBL108275724878615BindingDB-show
CHEMBL108275824878398BindingDB-show
CHEMBL108307224877013BindingDB-show
CHEMBL108307324878503BindingDB-show
CHEMBL108307424877716BindingDB-show
CHEMBL108314046889888BindingDB-show
CHEMBL108314124878164BindingDB-show
CHEMBL108314224878052BindingDB-show
CHEMBL108314346889889BindingDB-show
CHEMBL108335146889386BindingDB-show
CHEMBL108335246889387BindingDB-show
CHEMBL108345524878396BindingDB-show
CHEMBL108396546889388BindingDB-show
CHEMBL108396646889389BindingDB-show
CHEMBL108396746889390BindingDB-show
CHEMBL108410624863112BindingDB-show
CHEMBL108410724758992BindingDB-show
CHEMBL108479124878617BindingDB-show
CHEMBL108479224878618BindingDB-show
CHEMBL108479546889347BindingDB-show
CHEMBL108489024863535BindingDB-show
CHEMBL108489224863113BindingDB-show
CHEMBL108490046890138BindingDB-show
CHEMBL108494724877483BindingDB-show
CHEMBL108503546889348BindingDB-show
CHEMBL108514146890036BindingDB-show
CHEMBL108546824878165BindingDB-show
CHEMBL108570024878504BindingDB-show
CHEMBL108570624877599BindingDB-show
CHEMBL108593546889405BindingDB-show
CHEMBL108607846889855BindingDB-show
CHEMBL108632124878054BindingDB-show
CHEMBL108632224878170BindingDB-show
CHEMBL108654324878508BindingDB-show
CHEMBL108654424740244BindingDB-show
CHEMBL108654524878397BindingDB-show
CHEMBL108673646880951BindingDB-show
CHEMBL108765046880136BindingDB-show
CHEMBL108908224822704BindingDB-show
CHEMBL108911646885625BindingDB-show
CHEMBL109275444541014BindingDB-show
CHEMBL109562644605035BindingDB-show
CHEMBL109562744605037BindingDB-show
CHEMBL121517144197572BindingDB-show
CHEMBL121530446864283BindingDB-show
CHEMBL121552444198874BindingDB-show
CHEMBL121552646901260BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL18843411393719BindingDB-show
CHEMBL18965723646578BindingDB-show
CHEMBL37921811314340BindingDB-show
CHEMBL44518025023721BindingDB-show
CHEMBL45048725023723BindingDB-show
CHEMBL46649615295578BindingDB-show
CHEMBL46706924825721BindingDB-show
CHEMBL46812544575073BindingDB-show
CHEMBL47781724766030BindingDB-show
CHEMBL48124844575127BindingDB-show
CHEMBL49306625023717BindingDB-show
CHEMBL49306725023718BindingDB-show
CHEMBL49325125023720BindingDB-show
CHEMBL49387425023725BindingDB-show
CHEMBL49387525023727BindingDB-show
CHEMBL49391125023714BindingDB-show
CHEMBL49428025023728BindingDB-show
CHEMBL49488225023724BindingDB-show
CHEMBL50615325023715BindingDB-show
CHEMBL51141025207521BindingDB-show
CHEMBL51911344575126BindingDB-show
CHEMBL52164225023735BindingDB-show
CHEMBL52182311256399BindingDB-show
CHEMBL52305725023722BindingDB-show
CHEMBL52352325023726BindingDB-show
CHEMBL52358644592504BindingDB-show
CHEMBL52369525023716BindingDB-show
CHEMBL53909945266020BindingDB-show
CHEMBL55114044188627BindingDB-show
CHEMBL56545244542926BindingDB-show
CHEMBL56629845483267BindingDB-show
CHEMBL56712445485083BindingDB-show
CHEMBL56760345483209BindingDB-show
CHEMBL57011644543080BindingDB-show
CHEMBL57012644477445BindingDB-show
CHEMBL57082044543079BindingDB-show
CHEMBL57086545487634BindingDB-show
CHEMBL57158123627212BindingDB-show
CHEMBL5719489810884BindingDB-show
CHEMBL57291145483184BindingDB-show
CHEMBL57315145483257BindingDB-show
CHEMBL57315245483258BindingDB-show
CHEMBL57534045483178BindingDB-show
CHEMBL57555545483176BindingDB-show
CHEMBL57556245483303BindingDB-show
CHEMBL57557545483322BindingDB-show
CHEMBL57574145483283BindingDB-show
CHEMBL57575945483177BindingDB-show
CHEMBL57576145483248BindingDB-show
CHEMBL57576545483304BindingDB-show
CHEMBL57579845483326BindingDB-show
CHEMBL57594045483285BindingDB-show
CHEMBL57596245483302BindingDB-show
CHEMBL57597345483249BindingDB-show
CHEMBL57597445483250BindingDB-show
CHEMBL57717745483284BindingDB-show
CHEMBL57864345483179BindingDB-show
CHEMBL58429145483210BindingDB-show
CHEMBL58933646230025BindingDB-show
CHEMBL58933746230026BindingDB-show
CHEMBL58957711703935BindingDB-show
CHEMBL58957846230023BindingDB-show
CHEMBL58965546229921BindingDB-show
CHEMBL58965646229922BindingDB-show
CHEMBL59023846230027BindingDB-show
CHEMBL59031311560302BindingDB-show
CHEMBL59104746230133BindingDB-show
CHEMBL59127111536733BindingDB-show
CHEMBL59127211609495BindingDB-show
CHEMBL59128546230134BindingDB-show
CHEMBL59128746230131BindingDB-show
CHEMBL59175411503627BindingDB-show
CHEMBL59198646230081BindingDB-show
CHEMBL59270146230078BindingDB-show
CHEMBL59270246230079BindingDB-show
CHEMBL59289846226435BindingDB-show
CHEMBL59349046225540BindingDB-show
CHEMBL59451746226371BindingDB-show
CHEMBL59474811575817BindingDB-show
CHEMBL59474911611566BindingDB-show
CHEMBL59475046226414BindingDB-show
CHEMBL59547646226348BindingDB-show
CHEMBL59568411518055BindingDB-show
CHEMBL59568546226370BindingDB-show
CHEMBL59570811633229BindingDB-show
CHEMBL59570911495551BindingDB-show
CHEMBL59637946226389BindingDB-show
CHEMBL59833644819015BindingDB-show
CHEMBL59896346230172BindingDB-show
CHEMBL59916246230174BindingDB-show
CHEMBL59916346216813BindingDB-show
CHEMBL60023611667631BindingDB-show
CHEMBL60084911716019BindingDB-show
CHEMBL60183446230024BindingDB-show
CHEMBL60193511530100BindingDB-show
CHEMBL60204146230135BindingDB-show
CHEMBL60232646230132BindingDB-show
CHEMBL60270611694866BindingDB-show
CHEMBL60275346230080BindingDB-show
CHEMBL60406046226413BindingDB-show
CHEMBL60468411648365BindingDB-show
CHEMBL60493446230173BindingDB-show
CHEMBL60573211690618BindingDB-show
CHEMBL60573346226390BindingDB-show
CHEMBL61078546230251BindingDB-show
CHEMBL61138646230175BindingDB-show
ChemDiv3_004686599038BindingDB-show
Fasudil hydrochloride3547BindingDB-show
Fasudil hydrochloride3547SuperTarget-show
Fasudil hydrochloride163751SuperTarget-show
HYDROXYFASUDIL3064778DrugBank-show
Kinome_248146224684BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_71446886323BindingDB-show
Lestaurtinib126565BindingDB-show
MLS0007773675357223BindingDB-show
PKC-4129829523BindingDB-show
S1526_Selleck24889392BindingDB-show
sorafenibum216239BindingDB-show
staurosporine44299148BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
y-27632448042BindingDB-show
ZINC00051756684961BindingDB-show
ZINC00053816607858BindingDB-show
ZINC00204903753058BindingDB-show
Synonyms:
p160 ROCK-1
p160ROCK
Renal carcinoma antigen NY-REN-35
Rho-associated protein kinase 1
Rho-associated, coiled-coil-containing protein kinase 1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
SLK_CAVPO3418.7
EEA1_HUMAN33.119.1
TOP2A_HUMAN32.317.7
TOP2_CRIFA31.817.6
DPOLA_HUMAN3116.2
DAPK1_HUMAN30.515.6
MYH11_CHICK30.417.2
Q59FN5_HUMAN29.916
TOP2_YEAST29.315.3
RPOC_THET829.316.8
POL_HV1Z229.115.2
KIF11_HUMAN28.715.6
RET3_HUMAN28.716.2
POL_HV1A228.716
POL_HV1N528.516
RAD50_PYRFU28.314.7
POL_HV1B128.115.6
POL_HV1H228.115.5
TOP2A_RAT28.115.3
PYC_HUMAN28.113.8
BGA2_ECOLI28.115.6
SN_MOUSE2817
MAP2_HUMAN27.815.7
Q68DE6_HUMAN27.815.4
POL_HV1Y227.815.9
POL_FIVPE27.714.4
BXB_CLOBO27.614.6
SYIC_HUMAN27.614.6
METH_HUMAN27.515.8
MDR1_HUMAN27.414.9
Protein-Protein Interactions: