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Target Details

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Name:C-ret
Uniprot name:RET_HUMAN
Accession Numbers:P07949 Q15250 Q9H4A2
EC-Number:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1XPD 2IVS 2IVT 2IVU 2IVV
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2zaz23644582BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
7MP10062694BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
AZD-115211497983BindingDB-show
Bio2_0004136610353BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:54743644560358BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL10330710561847BindingDB-show
CHEMBL107954511200284BindingDB-show
CHEMBL108150911189588BindingDB-show
CHEMBL108551124762205BindingDB-show
CHEMBL109440824993189BindingDB-show
CHEMBL116981246838965BindingDB-show
CHEMBL117021746839102BindingDB-show
CHEMBL117021846839103BindingDB-show
CHEMBL117035346838816BindingDB-show
CHEMBL117035446838817BindingDB-show
CHEMBL117055046838821BindingDB-show
CHEMBL117055146838822BindingDB-show
CHEMBL117055246838962BindingDB-show
CHEMBL117056346838818BindingDB-show
CHEMBL117056446838819BindingDB-show
CHEMBL117076046838963BindingDB-show
CHEMBL117152046838964BindingDB-show
CHEMBL117168846839105BindingDB-show
CHEMBL117196046838966BindingDB-show
CHEMBL117214746838967BindingDB-show
CHEMBL117214846838968BindingDB-show
CHEMBL117230046838820BindingDB-show
CHEMBL117269646839104BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL125891311847343BindingDB-show
CHEMBL127023024809764BindingDB-show
CHEMBL127617944187005BindingDB-show
CHEMBL128816049839481BindingDB-show
CHEMBL23068611562302BindingDB-show
CHEMBL23692825023835BindingDB-show
CHEMBL23712625023826BindingDB-show
CHEMBL23712825023827BindingDB-show
CHEMBL23734425023829BindingDB-show
CHEMBL23734525023830BindingDB-show
CHEMBL23734625023831BindingDB-show
CHEMBL2373479927432BindingDB-show
CHEMBL23755725023833BindingDB-show
CHEMBL24606444440761BindingDB-show
CHEMBL24668523655831BindingDB-show
CHEMBL24771344440766BindingDB-show
CHEMBL24871212001530BindingDB-show
CHEMBL24871312001529BindingDB-show
CHEMBL24889044441750BindingDB-show
CHEMBL24889144441751BindingDB-show
CHEMBL24909444441752BindingDB-show
CHEMBL24909544441753BindingDB-show
CHEMBL24909644441755BindingDB-show
CHEMBL24930244441756BindingDB-show
CHEMBL24930344441758BindingDB-show
CHEMBL24930444441759BindingDB-show
CHEMBL24950044441760BindingDB-show
CHEMBL24950144441762BindingDB-show
CHEMBL24950244441763BindingDB-show
CHEMBL24951844441770BindingDB-show
CHEMBL24951944441771BindingDB-show
CHEMBL25173944441764BindingDB-show
CHEMBL25174044441765BindingDB-show
CHEMBL39285625023824BindingDB-show
CHEMBL39535825023828BindingDB-show
CHEMBL39535925023832BindingDB-show
CHEMBL39609844440760BindingDB-show
CHEMBL39904244441761BindingDB-show
CHEMBL39920825023834BindingDB-show
CHEMBL40056844441767BindingDB-show
CHEMBL40056911963996BindingDB-show
CHEMBL40074944441766BindingDB-show
CHEMBL40085944441754BindingDB-show
CHEMBL40090644441768BindingDB-show
CHEMBL40106444441757BindingDB-show
CHEMBL42947844441769BindingDB-show
CHEMBL45835225148929BindingDB-show
CHEMBL45844011688423BindingDB-show
CHEMBL45844125148935BindingDB-show
CHEMBL46116225147774BindingDB-show
CHEMBL46134025147782BindingDB-show
CHEMBL46134144563277BindingDB-show
CHEMBL47310144563339BindingDB-show
CHEMBL50137144563338BindingDB-show
CHEMBL50323625148932BindingDB-show
CHEMBL51239244563276BindingDB-show
CHEMBL51239344563313BindingDB-show
CHEMBL51587124951139BindingDB-show
CHEMBL57104024883287BindingDB-show
CHEMBL57592544622967BindingDB-show
CHEMBL59169646233144BindingDB-show
CHEMBL59265146233299BindingDB-show
CHEMBL59697446233145BindingDB-show
CHEMBL59717646233146BindingDB-show
CHEMBL59717746233147BindingDB-show
CHEMBL59718115551239BindingDB-show
CHEMBL59734511818023BindingDB-show
CHEMBL59736546233298BindingDB-show
CHEMBL59759246228508BindingDB-show
CHEMBL59775446233287BindingDB-show
CHEMBL59796046233185BindingDB-show
CHEMBL59797146233297BindingDB-show
CHEMBL59862646228822BindingDB-show
CHEMBL59899146233183BindingDB-show
CHEMBL59919246233184BindingDB-show
CHEMBL59922445139989BindingDB-show
CHEMBL59942845139991BindingDB-show
CHEMBL59980746233681BindingDB-show
CHEMBL59980822394608BindingDB-show
CHEMBL59980946233683BindingDB-show
CHEMBL60123246233109BindingDB-show
CHEMBL60187146233106BindingDB-show
CHEMBL60207346233107BindingDB-show
CHEMBL60207446233108BindingDB-show
CHEMBL60212346228951BindingDB-show
CHEMBL60348246228648BindingDB-show
CHEMBL60349146233110BindingDB-show
CHEMBL60361811482682BindingDB-show
CHEMBL60471210429593BindingDB-show
CHEMBL60500046233648BindingDB-show
CHEMBL60633446233680BindingDB-show
CHEMBL60758146233682BindingDB-show
CHEMBL60842446233143BindingDB-show
CHEMBL8904010593765BindingDB-show
CHEMBL8948310562777BindingDB-show
CHEMBL9027710663503BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Elagostasine5281855BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Indolinone based inhibitor, 1b23647607BindingDB-show
Indolinone based inhibitor, 3g23647620BindingDB-show
K000046419834BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
nchembio.90-comp111715767BindingDB-show
NVP-TAE68416038120BindingDB-show
oxindole i5908088BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1194_Selleck24756910BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
Semaxinib5329098BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine44299148BindingDB-show
SU 43126450842BindingDB-show
SU 49845353975BindingDB-show
SU-1481310138259BindingDB-show
su66565312137BindingDB-show
Sunitinib5329102BindingDB-show
Sunitinib5329102DrugBank-show
Tandutinib3038522BindingDB-show
Trisubstituted 4-anilinoquinoline, 2925023825BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VEGF Receptor 3 Kinase Inhibitor, MAZ519839842BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
ZINC004893591749976BindingDB-show
ZINC022590371886699BindingDB-show
ZINC022731801898760BindingDB-show
Synonyms:
C-ret
Proto-oncogene tyrosine-protein kinase receptor ret
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
EPHB2_MOUSE3621.7
Q6IQ28_HUMAN34.822.9
KIT_HUMAN34.823
FGFR4_HUMAN3423.6
FGFR1_MOUSE33.923.6
FGFR2_HUMAN33.823.4
PGFRB_HUMAN33.820.8
CSF1R_HUMAN33.722.4
FGFR3_HUMAN33.424.2
VGFR2_HUMAN33.220.7
FLT3_HUMAN3322.3
EPHB1_HUMAN32.920.5
FGFR1_HUMAN32.522.2
PGFRA_HUMAN32.420.5
VGFR1_HUMAN32.320.2
EGFR_HUMAN3220.3
JAK3_HUMAN31.621.3
JAK3_RAT31.521.2
JAK3_MOUSE31.320.8
KPC1_CANAL31.117.2
ERBB2_HUMAN30.920.1
EGFR_MOUSE30.720.4
VGFR3_HUMAN30.620.6
Q59FL8_HUMAN30.218.7
MET_HUMAN29.718.4
ADCY2_RAT29.716
B9WE39_CANDC29.616.9
GRID2_HUMAN29.217.1
XYNY_CLOTM29.217.7
SYAM_HUMAN29.119
Protein-Protein Interactions: