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Target Details

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Name:ORF1ab polyprotein
Uniprot name:R1AB_CVHSA
Accession Numbers:P0C6X7 P59641 Q6WGN0 Q7T697 Q808C0 Q80BV7 Q80BV8 Q80E51
EC-Number:-
Organism:Human SARS coronavirus
SARS-CoV
Severe acute respiratory syndrome coronavirus
PDB IDs:1O5S 1P76 1P9T 1PA5 1PUK 1Q1X 1Q2W 1QZ8 1SXF 1UJ1 1UK2 1UK3 1UK4 1UW7 1WOF 1YSY 1Z1I 1Z1J 2A5A 2A5I 2A5K 2ACF 2AHM 2AJ5 2ALV 2AMD 2AMQ 2BX3 2BX4 2C3S 2D2D 2DUC 2FAV 2FE8 2FYG 2G1F 2G9T 2GA6 2GDT 2GRI 2GT7 2GT8 2GTB 2GX4 2GZ7 2GZ8 2GZ9 2H2Z 2H85 2HOB 2HSX 2IDY 2JZD 2JZE 2JZF 2K87 2KAF 2OP9 2OZK 2PWX 2Q6G 2QC2 2QCY 2QIQ 2RHB 2RNK 2V6N 2VJ1 2YY4 2Z3C 2Z3D 2Z3E 2Z94 2Z9G 2Z9J 2Z9K 2Z9L 3D62 3E9S 3EBN
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
(E)-(S)-4-[(S)-2-((S)-2-TERT-BUTOXYCARBONYLAMINO-3-METHYL-BUTYRYLAMINO)-2-PHENYL-ACETYLAMINO]-5-(2-OXO-PYRROLIDIN-3-YL)-PENT-2-ENOIC ACID ETHYL ESTER6323298DrugBank-show
2,5-dimethyl-4-nitro-N-[(5-thiophen-2-ylthiophen-2-yl)methyl]pyrazol-3-ami4305683BindingDB-show
2-(2-acetylphenyl)sulfonylbenzoic Acid4270495BindingDB-show
2-METHYL-2,4-PENTANEDIOL5288834DrugBank-show
2-[(5-cyano-4-oxo-6-phenyl-1H-pyrimidin-2-yl)sulfanyl]-N-[3-(trifluorometh2167624BindingDB-show
4-(5-chlorothiophen-2-yl)-2-(thiophen-2-ylsulfonylmethyl)-1,3-thiazole2809432BindingDB-show
4-Nitrophenyl sulfone70871BindingDB-show
5-chloro-3-pyridinyl 2-furoate7230550BindingDB-show
AC1L9VAI501651BindingDB-show
AC1LALL7515954BindingDB-show
AC1LALLM515962BindingDB-show
AC1LALLS515964BindingDB-show
AC1LMCQQ1128176BindingDB-show
AC1LO0WK1212367BindingDB-show
AC1MCEUI2742278BindingDB-show
AC1MCISQ2744814BindingDB-show
AC1MCIUI2744846BindingDB-show
AC1MCIVU2744870BindingDB-show
AC1MCK262745640BindingDB-show
AC1MCK2W2745653BindingDB-show
AC1MCKKC2745968BindingDB-show
AC1MDFP02810524BindingDB-show
AC1ME3BL2820912BindingDB-show
AC1ME3BR2820914BindingDB-show
AC1ME4042821293BindingDB-show
AC1MFFWD2918614BindingDB-show
AC1MFGM02918926BindingDB-show
AC1MGL0J2962669BindingDB-show
AC1MH5RG2946678BindingDB-show
AC1O53DF6476897BindingDB-show
AC1O55QX6478229BindingDB-show
AG7088 analogue 1b15959291BindingDB-show
AG7088 analogue 1c11642725BindingDB-show
AG7088 analogue 1d15959292BindingDB-show
AG7088 analogue 2b15959293BindingDB-show
AG7088 analogue 2c15956553BindingDB-show
AG7088 analogue 3a15959294BindingDB-show
AG7088 analogue 3b15959295BindingDB-show
AG7088 analogue 3c15959296BindingDB-show
AG7088 analogue 3d15959297BindingDB-show
AG7088 analogue 4a15959298BindingDB-show
AG7088 analogue 4b15959299BindingDB-show
AG7088 analogue 4c15959300BindingDB-show
AG7088 analogue 4d15959301BindingDB-show
Anilide Inhibitor 2a11317290BindingDB-show
Anilide Inhibitor 3d11262151BindingDB-show
Anilide Inhibitor 3h11467858BindingDB-show
Anilide Inhibitor 3o11181465BindingDB-show
Anilide Inhibitor 3p11227702BindingDB-show
Anilide Inhibitor 4j15959316BindingDB-show
Anilide Inhibitor 4k15959317BindingDB-show
Anilide Inhibitor 5b11491101BindingDB-show
AO-080/41280681990824BindingDB-show
ASN 051115603194487BindingDB-show
BAS 027297642171126BindingDB-show
BAS 03275870763192BindingDB-show
BAS 037872932918713BindingDB-show
CBDivE_0035892775844BindingDB-show
CHEBI:424032822496BindingDB-show
CHEMBL1082539882716BindingDB-show
CHEMBL11859610642441BindingDB-show
CHEMBL18569844398167BindingDB-show
CHEMBL18757944398160BindingDB-show
CHEMBL18759844398207BindingDB-show
CHEMBL18771744398343BindingDB-show
CHEMBL18848744398002BindingDB-show
CHEMBL18898344398231BindingDB-show
CHEMBL19074311796320BindingDB-show
CHEMBL19157544398546BindingDB-show
CHEMBL19919944404067BindingDB-show
CHEMBL20928711515424BindingDB-show
CHEMBL21052511644322BindingDB-show
CHEMBL21354311444522BindingDB-show
CHEMBL22223416203681BindingDB-show
CHEMBL22262816203796BindingDB-show
CHEMBL22273516204324BindingDB-show
CHEMBL22276916203797BindingDB-show
CHEMBL22551516204322BindingDB-show
CHEMBL36513411667869BindingDB-show
CHEMBL36546944398344BindingDB-show
CHEMBL37092344398436BindingDB-show
CHEMBL37171925256829BindingDB-show
CHEMBL37972711630144BindingDB-show
CHEMBL38372510645393BindingDB-show
CHEMBL42608244398055BindingDB-show
CHEMBL42689816204318BindingDB-show
CHEMBL49276844511706BindingDB-show
CHEMBL49276944593565BindingDB-show
CHEMBL49277125256828BindingDB-show
CHEMBL49277244511707BindingDB-show
CHEMBL52271025072274BindingDB-show
CHEMBL54964645270971BindingDB-show
CHEMBL55025645270979BindingDB-show
CHEMBL55113045271826BindingDB-show
CHEMBL55113144517748BindingDB-show
CHEMBL55133445271831BindingDB-show
CHEMBL55152945271832BindingDB-show
CHEMBL55650145273625BindingDB-show
CHEMBL56013645268445BindingDB-show
CHEMBL56039245269292BindingDB-show
CHEMBL56093345268452BindingDB-show
CID 1178695711786957BindingDB-show
Compound 1 analog 102799801BindingDB-show
Compound 1 analog 142799800BindingDB-show
Compound 2 analog 163776668BindingDB-show
Compound 2 analog 204398304BindingDB-show
Compound 2 analog 2323644661BindingDB-show
CY610062715BindingDB-show
D3F2799606BindingDB-show
DB045956323191DrugBank-show
DB046135287569DrugBank-show
dipeptidomimetic unsaturated ester 18a15959302BindingDB-show
dipeptidomimetic unsaturated ester 18b15959303BindingDB-show
dipeptidomimetic unsaturated ester 18c11555658BindingDB-show
dipeptidomimetic unsaturated ester 18d15959304BindingDB-show
dipeptidomimetic unsaturated ester 18e23645527BindingDB-show
Maybridge3_0034142819269BindingDB-show
Maybridge3_0073722745617BindingDB-show
N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE6323379DrugBank-show
Nitrophenyl chlorsalicylamide4477BindingDB-show
Ruprintrivir6440352BindingDB-show
STK0279241342108BindingDB-show
TG-020522111456186BindingDB-show
Xanthaurine5280343BindingDB-show
ZINC000754652726174BindingDB-show
ZINC000754742726176BindingDB-show
ZINC000929502800273BindingDB-show
ZINC001489012820775BindingDB-show
ZINC001659762819040BindingDB-show
ZINC010362442797358BindingDB-show
ZINC010403292823615BindingDB-show
ZINC010432942727994BindingDB-show
ZINC013764341465905BindingDB-show
ZINC021554292774892BindingDB-show
ZINC021631602774667BindingDB-show
ZINC029956012292729BindingDB-show
ZINC043249942811874BindingDB-show
Synonyms:
ORF1ab polyprotein
pp1ab
Replicase polyprotein 1ab
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
R1AB_CVPPU51.136.5
Protein-Protein Interactions:
No data available