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Target Details

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Name:Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Uniprot name:PK3CB_HUMAN
Accession Numbers:P42338 Q24JU2
EC-Number:2.7.1.153
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2′-Amino-3′-methoxyflavone4713PROMISCUOUSPMID 14737074show
2-morpholin-4-yl-8-phenylchromen-4-one3973BindingDB-show
3-(1,3-benzothiazol-2-yl)-7-hydroxy-2H-chromen-2-one5398639BindingDB-show
4441313444413134BindingDB-show
AC1NUCB25424054BindingDB-show
BAS 08315390913795BindingDB-show
BiomolKI2_0000029908783BindingDB-show
CHEBI:65321244424680BindingDB-show
CHEBI:65350444424681BindingDB-show
CHEMBL107702346180606BindingDB-show
CHEMBL108262146891474BindingDB-show
CHEMBL108319246180604BindingDB-show
CHEMBL108380946180663BindingDB-show
CHEMBL108381044620965BindingDB-show
CHEMBL108492625242324BindingDB-show
CHEMBL108516044620964BindingDB-show
CHEMBL108517724946706BindingDB-show
CHEMBL108517846180666BindingDB-show
CHEMBL108692311576772BindingDB-show
CHEMBL108692424993871BindingDB-show
CHEMBL109197825207689BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL125765346220225BindingDB-show
CHEMBL125851746947264BindingDB-show
CHEMBL128997510475366BindingDB-show
CHEMBL129074450908894BindingDB-show
CHEMBL20865211522078BindingDB-show
CHEMBL23905044436951BindingDB-show
CHEMBL23905144436952BindingDB-show
CHEMBL23905244436955BindingDB-show
CHEMBL23947544436961BindingDB-show
CHEMBL24011844436976BindingDB-show
CHEMBL24033524809743BindingDB-show
CHEMBL24033644436979BindingDB-show
CHEMBL24455917751063BindingDB-show
CHEMBL39207044436964BindingDB-show
CHEMBL39207144436967BindingDB-show
CHEMBL39352644436954BindingDB-show
CHEMBL39374744436972BindingDB-show
CHEMBL39710544436980BindingDB-show
CHEMBL39778044436981BindingDB-show
CHEMBL39779644436953BindingDB-show
CHEMBL41380244436970BindingDB-show
CHEMBL41380344436971BindingDB-show
CHEMBL44904923642272BindingDB-show
CHEMBL44978644577853BindingDB-show
CHEMBL45188344577854BindingDB-show
CHEMBL45323211998685BindingDB-show
CHEMBL45324044577594BindingDB-show
CHEMBL46360644578037BindingDB-show
CHEMBL46610611998447BindingDB-show
CHEMBL46695611998448BindingDB-show
CHEMBL46695711998444BindingDB-show
CHEMBL46739444577920BindingDB-show
CHEMBL46739544577922BindingDB-show
CHEMBL46755244577918BindingDB-show
CHEMBL46755344577919BindingDB-show
CHEMBL46756144577950BindingDB-show
CHEMBL46796644577953BindingDB-show
CHEMBL46821844577850BindingDB-show
CHEMBL46903524768579BindingDB-show
CHEMBL46905211998445BindingDB-show
CHEMBL46905744578038BindingDB-show
CHEMBL46905944578040BindingDB-show
CHEMBL46919324956159BindingDB-show
CHEMBL46919444577592BindingDB-show
CHEMBL46920024956158BindingDB-show
CHEMBL46920111998690BindingDB-show
CHEMBL46920244577639BindingDB-show
CHEMBL46920844577641BindingDB-show
CHEMBL46920944593630BindingDB-show
CHEMBL46924844577851BindingDB-show
CHEMBL46927044577914BindingDB-show
CHEMBL47695311998564BindingDB-show
CHEMBL47778744578074BindingDB-show
CHEMBL47799911998565BindingDB-show
CHEMBL47842544578108BindingDB-show
CHEMBL47863344578109BindingDB-show
CHEMBL49042825032963BindingDB-show
CHEMBL49633244580686BindingDB-show
CHEMBL50461644577951BindingDB-show
CHEMBL51122844577921BindingDB-show
CHEMBL51160544577916BindingDB-show
CHEMBL51209144577917BindingDB-show
CHEMBL51209244593631BindingDB-show
CHEMBL51229316081736BindingDB-show
CHEMBL51244025052783BindingDB-show
CHEMBL51247044578039BindingDB-show
CHEMBL51262444577952BindingDB-show
CHEMBL51264844577593BindingDB-show
CHEMBL51265044577638BindingDB-show
CHEMBL51281524955795BindingDB-show
CHEMBL51283444577640BindingDB-show
CHEMBL51392411998803BindingDB-show
CHEMBL51406111998563BindingDB-show
CHEMBL51486911999032BindingDB-show
CHEMBL56857444610761BindingDB-show
CHEMBL57083345488079BindingDB-show
CHEMBL58387425261554BindingDB-show
CHEMBL58925844187953BindingDB-show
CID 982507010275789BindingDB-show
GDC-094117755052BindingDB-show
Lestaurtinib126565BindingDB-show
Lificiguat5712PROMISCUOUSPMID 17213816show
MASTPROM3795PROMISCUOUSPMID 17353907show
nchembio.293-comp1044475985BindingDB-show
nchembio.293-comp1344475989BindingDB-show
nchembio.293-comp325097993BindingDB-show
nchembio.293-comp425097994BindingDB-show
nchembio.293-comp544475987BindingDB-show
nchembio.293-comp644475986BindingDB-show
nchembio.293-comp744475990BindingDB-show
nchembio.293-comp944475988BindingDB-show
PI 3-Kgamma/CKII Inhibitor11630874BindingDB-show
PI-1039884685BindingDB-show
PIK-396852165BindingDB-show
PKC-4129829523BindingDB-show
pyrazolo pyrimidine, 1025260915BindingDB-show
S1226_Selleck16736978BindingDB-show
S1526_Selleck24889392BindingDB-show
S2628_Selleck44516953BindingDB-show
SMR000037915622000BindingDB-show
sorafenibum216239BindingDB-show
STK2416172988969BindingDB-show
STK5694351627922BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
TG100-11510427712BindingDB-show
TG10111023652302BindingDB-show
thienopyrimidine derivative, 19901372BindingDB-show
wortmannin312145BindingDB-show
ZINC00229432622262BindingDB-show
ZINC00274998617191BindingDB-show
ZINC034953672612441BindingDB-show
ZINC2864252816066756BindingDB-show
ZSTK47411647372BindingDB-show
Synonyms:
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform
PI3-kinase p110 subunit beta
PI3K
PI3Kbeta
PtdIns-3-kinase p110
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PK3CB_MOUSE97.295.3
PK3CD_HUMAN72.556.4
PK3CD_MOUSE71.255
PK3CA_MOUSE57.339.7
PK3CA_HUMAN57.139.8
PK3CG_MOUSE48.231.7
PK3CG_HUMAN47.930.5
PK3CG_PIG47.830.5
PK3C3_HUMAN33.220.1
PK3C3_MOUSE33.120
A3LQL4_PICST31.918.3
PI4KB_RAT31.817.4
PUR2_HUMAN31.217.2
PK3C3_RAT31.119.1
CLPB_THET83117.7
TLR8_HUMAN30.516.6
Q495P6_HUMAN30.516.6
Q495P7_HUMAN30.416.6
P3C2A_HUMAN30.219.8
P91635_DROME30.218.6
PDE5A_RAT30.116.2
SECA1_MYCTU29.816
PLD2_HUMAN29.716.3
DPO1_ECOLI29.316.7
ACE_HUMAN29.316.6
CSKP_HUMAN29.317.3
EPHB2_MOUSE29.215.8
JAK2_RAT29.116.5
JAK2_HUMAN29.116.6
KIF11_HUMAN28.816.9
Protein-Protein Interactions: