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Name:Proto-oncogene serine/threonine-protein kinase Pim-1
Uniprot name:PIM1_HUMAN
Accession Numbers:P11309 Q38RT9 Q96RG3
EC-Number:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1XQZ 1XR1 1XWS 1YHS 1YI3 1YI4 1YWV 1YXS 1YXT 1YXU 1YXV 1YXX 2BIK 2BIL 2BZH 2BZI 2BZJ 2BZK 2C3I 2J2I 2O3P 2O63 2O64 2O65 2OBJ 2OI4 3BGP 3BGQ 3BGZ 3BWF 3C4E 3CXW 3CY2 3CY3 3DCV 3F2A
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(5Z)-5-[(4-fluorophenyl)methylidene]-1,3-thiazolidine-2,4-dione1239884BindingDB-show
(R)-5,7-dihydroxyflavanone667544BindingDB-show
2,3-dihydroxy-1-methylquinolin-4-one657135DrugBank-show
2,3-diphenyl-1H-indole-7-carboxylic acid5003498BindingDB-show
2-morpholin-4-yl-8-phenylchromen-4-one3973BindingDB-show
2-morpholin-4-yl-8-phenylchromen-4-one3973DrugBank-show
2obj1235170BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
3-[(4-hydroxyphenyl)amino]indol-2-one611002DrugBank-show
5-(4-chlorobenzylidene)-1,3-thiazolidine-2,4-dione1382447BindingDB-show
5-(4-methoxybenzylidene)-1,3-thiazolidine-2,4-dione5373936BindingDB-show
5-Arylidene-3-benzylhydantoin, 26c25190439BindingDB-show
5-Arylidene-3-benzylhydantoin, 27c-225190440BindingDB-show
5-Arylidene-3-benzylhydantoin, 28c25190441BindingDB-show
5-Arylidene-3-benzylhydantoin, 31c25190442BindingDB-show
5-Deoxykaempferol5281611BindingDB-show
7-Hydroxyflavone5281894BindingDB-show
7-Hydroxyflavonol5393152BindingDB-show
8-hydroxy-2-methylquinoline-7-carboxylic acid469823BindingDB-show
ABT-86911485656BindingDB-show
AC1L9UUI456402BindingDB-show
AC1L9XDZ477727BindingDB-show
AC1LAN1Q491467BindingDB-show
AC1LI4VO848933BindingDB-show
AC1LQOEU1379638BindingDB-show
AC1LUWS91641790BindingDB-show
AC1LUWSF1641793BindingDB-show
AC1M3T3U2243909BindingDB-show
AC1MDSYV2816326BindingDB-show
AC1MHPBH3008941BindingDB-show
AC1MHPBK3008942BindingDB-show
AC1MHPBN3008943BindingDB-show
AC1MHPBQ3008944BindingDB-show
AC1MHPBT3008947BindingDB-show
AC1MHPBW3008948BindingDB-show
AC1MKI6C3157596BindingDB-show
AC1NU2CD5393164BindingDB-show
AC1NUK6F5481107BindingDB-show
AC1NUK6I5481109BindingDB-show
AC1NUKYC5481655BindingDB-show
AC1NX3S75742709BindingDB-show
AC1NX3S95742710BindingDB-show
AC1O02ZT6026872BindingDB-show
AC1O0BDU5985287BindingDB-show
AC1O51RK6475553BindingDB-show
AC1O51RT6475556BindingDB-show
AC1O51RW6475557BindingDB-show
AC1O585S6479612BindingDB-show
AC1O6QRW6532358BindingDB-show
ADENYLYL IMIDODIPHOSPHATE33113DrugBank-show
AG-690/370991071206018BindingDB-show
AIDS0604675481111BindingDB-show
AIDS0604715481117BindingDB-show
AIDS0891085481651BindingDB-show
AIDS08911010497153BindingDB-show
AIDS0891135481654BindingDB-show
AMG 70611667893BindingDB-show
AO-476/4114491711840847BindingDB-show
AO-476/4114491811840848BindingDB-show
AO-476/433803252816450BindingDB-show
AO-476/433803862816447BindingDB-show
Apigenine5280443BindingDB-show
AQ-149/42126255646970BindingDB-show
Articulatidin5280647BindingDB-show
AST-48711409972BindingDB-show
BAS 007276245407052BindingDB-show
BAS 02073596788302BindingDB-show
BAS 087709513157603BindingDB-show
BAS 08770954655134BindingDB-show
benzothienopyrimidinone deriv., 3a25174525BindingDB-show
Bio2_0004136610353BindingDB-show
BiomolKI_0000335083BindingDB-show
BIS050444120114BindingDB-show
Bisindolyl deriv. 115327726BindingDB-show
Bisindolylmaleimide I2396BindingDB-show
Canertinib156414BindingDB-show
Cannabiscetin5281672BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:15532315391968BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL109574246887815BindingDB-show
CHEMBL109574346887816BindingDB-show
CHEMBL109574446887817BindingDB-show
CHEMBL109615846887899BindingDB-show
CHEMBL109615946887900BindingDB-show
CHEMBL109633411194777BindingDB-show
CHEMBL109666746887868BindingDB-show
CHEMBL109680946887968BindingDB-show
CHEMBL109852946888009BindingDB-show
CHEMBL109878446887934BindingDB-show
CHEMBL122163346934144BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL124096146937301BindingDB-show
CHEMBL124100946937316BindingDB-show
CHEMBL124101152940742BindingDB-show
CHEMBL124312852945651BindingDB-show
CHEMBL124312952943221BindingDB-show
CHEMBL127023024809764BindingDB-show
CHEMBL14224611759459BindingDB-show
CHEMBL14241211722730BindingDB-show
CHEMBL18514016723801BindingDB-show
CHEMBL18870144397554BindingDB-show
CHEMBL34195111782377BindingDB-show
CHEMBL371396475560BindingDB-show
CHEMBL399586475559BindingDB-show
CHEMBL45056844574367BindingDB-show
CHEMBL45455725189322BindingDB-show
CHEMBL46766510333282BindingDB-show
CHEMBL46809710401467BindingDB-show
CHEMBL46829710332398BindingDB-show
CHEMBL4689409840025BindingDB-show
CHEMBL46894110378377BindingDB-show
CHEMBL47645244593656BindingDB-show
CHEMBL47645444582386BindingDB-show
CHEMBL49316844573834BindingDB-show
CHEMBL49316944219632BindingDB-show
CHEMBL49356144573866BindingDB-show
CHEMBL49419610359460BindingDB-show
CHEMBL49422144219633BindingDB-show
CHEMBL49422244573945BindingDB-show
CHEMBL4965871201120BindingDB-show
CHEMBL4967839965755BindingDB-show
CHEMBL49678425185171BindingDB-show
CHEMBL49697225185444BindingDB-show
CHEMBL49699425185442BindingDB-show
CHEMBL49820325185443BindingDB-show
CHEMBL51174510333921BindingDB-show
CHEMBL51209510016571BindingDB-show
CHEMBL51282910423197BindingDB-show
CHEMBL51368210448624BindingDB-show
CHEMBL5157789594375BindingDB-show
CHEMBL51631244588117BindingDB-show
CHEMBL52185044573946BindingDB-show
CHEMBL52249744573835BindingDB-show
CHEMBL52291625185174BindingDB-show
CHEMBL52358644592504BindingDB-show
CHEMBL57251344251518BindingDB-show
CHEMBL57251444472929BindingDB-show
CHEMBL57255044472925BindingDB-show
CHEMBL57255644472913BindingDB-show
CHEMBL57274325175355BindingDB-show
CHEMBL57274525174366BindingDB-show
CHEMBL57278144472945BindingDB-show
CHEMBL57278344472935BindingDB-show
CHEMBL57278444472936BindingDB-show
CHEMBL57280925175354BindingDB-show
CHEMBL57281044472917BindingDB-show
CHEMBL57281544472924BindingDB-show
CHEMBL57301144472944BindingDB-show
CHEMBL57301225174210BindingDB-show
CHEMBL57303644472939BindingDB-show
CHEMBL57303725175513BindingDB-show
CHEMBL57303844472911BindingDB-show
CHEMBL57304444472919BindingDB-show
CHEMBL57304544472947BindingDB-show
CHEMBL57304644472940BindingDB-show
CHEMBL57317644479711BindingDB-show
CHEMBL57346244472899BindingDB-show
CHEMBL57346344472948BindingDB-show
CHEMBL57347044472915BindingDB-show
CHEMBL57347525175022BindingDB-show
CHEMBL57347644472903BindingDB-show
CHEMBL57347744472902BindingDB-show
CHEMBL57347844472910BindingDB-show
CHEMBL57365925174523BindingDB-show
CHEMBL57369644472905BindingDB-show
CHEMBL57369744472906BindingDB-show
CHEMBL57370244472926BindingDB-show
CHEMBL57370544472920BindingDB-show
CHEMBL57392344472922BindingDB-show
CHEMBL57395644472904BindingDB-show
CHEMBL57395724963232BindingDB-show
CHEMBL57416844472916BindingDB-show
CHEMBL57416944472927BindingDB-show
CHEMBL57481944472900BindingDB-show
CHEMBL57525444472928BindingDB-show
CHEMBL57525544472930BindingDB-show
CHEMBL57526344472934BindingDB-show
CHEMBL57526444472943BindingDB-show
CHEMBL57546044472908BindingDB-show
CHEMBL57546144472938BindingDB-show
CHEMBL57546344472941BindingDB-show
CHEMBL57546925174855BindingDB-show
CHEMBL57547025175182BindingDB-show
CHEMBL57547144472933BindingDB-show
CHEMBL57567544472931BindingDB-show
CHEMBL57573944480198BindingDB-show
CHEMBL57638744251517BindingDB-show
CHEMBL57638844472942BindingDB-show
CHEMBL57673424963578BindingDB-show
CHEMBL58284444472921BindingDB-show
CHEMBL58309944472912BindingDB-show
CHEMBL58310645481526BindingDB-show
CHEMBL58318744472946BindingDB-show
CHEMBL58327344472918BindingDB-show
CHEMBL58338544472932BindingDB-show
CHEMBL58358125175023BindingDB-show
CHEMBL58369044472907BindingDB-show
CHEMBL58369144472914BindingDB-show
CHEMBL58391344472923BindingDB-show
CHEMBL58394744472909BindingDB-show
CHEMBL58397244241505BindingDB-show
CHEMBL58415925174524BindingDB-show
CHEMBL58416124849199BindingDB-show
CHEMBL58419544479467BindingDB-show
CHEMBL58456344472937BindingDB-show
CHEMBL58456444472901BindingDB-show
CHEMBL58518224963233BindingDB-show
CHEMBL59775446233287BindingDB-show
CHEMBL59922445139989BindingDB-show
CHEMBL59942845139991BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Digitoflavone5280445BindingDB-show
Dihydrochrysin68071BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Galangin flavanone5281607BindingDB-show
Gefitinib123631BindingDB-show
Glabranin124049BindingDB-show
Glyoxaline795DrugBank-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
IMIDAZOPYRIDAZIN 15459373BindingDB-show
IMIDAZOPYRIDAZIN 15459373DrugBank-show
Isoxazoloquinolinedione, 1025190458BindingDB-show
Isoxazoloquinolinedione, 1125190459BindingDB-show
Isoxazoloquinolinedione, 1225190460BindingDB-show
Isoxazoloquinolinedione, 1325190461BindingDB-show
Isoxazoloquinolinedione, 1825190462BindingDB-show
Isoxazoloquinolinedione, 625190454BindingDB-show
Isoxazoloquinolinedione, 725190455BindingDB-show
Isoxazoloquinolinedione, 825190456BindingDB-show
Isoxazoloquinolinedione, 925190457BindingDB-show
JNK Inhibitor V11422035BindingDB-show
K001526419807BindingDB-show
K004866419820BindingDB-show
K1639_SIGMA3035817BindingDB-show
Kinome_248146224684BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_325944251519BindingDB-show
Kinome_365525032704BindingDB-show
Kinome_365625190453BindingDB-show
Kinome_71446886323BindingDB-show
Krisolamine31420BindingDB-show
L-Cysteine, mercaptoethanol mixed disulfide170018DrugBank-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
MLS0007773675357223BindingDB-show
morin5281670BindingDB-show
Muskeladenylsaeure6083DrugBank-show
NCGC00165873-019949093BindingDB-show
NSC709506399090BindingDB-show
Pazopanib10113978BindingDB-show
Pelargidenolon5280863BindingDB-show
Phosphatidalserine68841DrugBank-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
pyrazine inhibitor, 124811794BindingDB-show
pyrazine inhibitor, 1524811585BindingDB-show
pyrazine inhibitor, 2024811691BindingDB-show
pyrazine inhibitor, 2324737654BindingDB-show
pyrazolopyridine, 1125190450BindingDB-show
pyridine inhibitor, 2724812008BindingDB-show
pyridone-based compound, 1825190451BindingDB-show
pyridone-based compound, 225190444BindingDB-show
pyridone-based compound, 2425190452BindingDB-show
pyridone-based compound, 325190445BindingDB-show
pyridone-based compound, 425190446BindingDB-show
pyridone-based compound, 525190447BindingDB-show
pyridone-based compound, 625190448BindingDB-show
pyridone-based compound, 825190449BindingDB-show
pyridone-based compound, 9917033BindingDB-show
Quercetagetin5281680BindingDB-show
RBT205 INHIBITOR448946DrugBank-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
ST0553615391140BindingDB-show
ST056258688853BindingDB-show
ST057709688718BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
STAUROSPORINE44259DrugBank-show
STK014501705543BindingDB-show
STK6440355878179BindingDB-show
STK7952221243769BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Superfustel5281614BindingDB-show
Tandutinib3038522BindingDB-show
TG0031893668BindingDB-show
thiazolidine-2,4-dione, 5a25185441BindingDB-show
thiazolidine-2,4-dione, 6a25189319BindingDB-show
thiazolidine-2,4-dione, 7a25189321BindingDB-show
triazolopyridazine compound, 125190443BindingDB-show
Tricetin5281701BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Xanthaurine5280343BindingDB-show
ZINC000787892727417BindingDB-show
ZINC001597182816444BindingDB-show
ZINC001597242816445BindingDB-show
ZINC001597332816448BindingDB-show
ZINC010357002816451BindingDB-show
ZINC012040641361334BindingDB-show
ZINC012313671379720BindingDB-show
ZINC025232153497823BindingDB-show
ZINC025670892765355BindingDB-show
ZINC031412756006914BindingDB-show
ZINC041050826076476BindingDB-show
ZINC044985723157072BindingDB-show
Synonyms:
Proto-oncogene serine/threonine-protein kinase Pim-1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PIM1_FELCA77.276.7
STK6_HUMAN3824.2
KAPA_YEAST34.920
MP2K4_HUMAN34.822.2
GSK3A_HUMAN33.620.9
PAK1_CAEEL33.218.3
MP2K3_MOUSE33.117.8
F16P2_HUMAN3316.6
MP2K1_RAT32.819.6
MP2K1_MOUSE32.819.6
MP2K1_HUMAN32.619.4
MP2K7_HUMAN32.520.9
DCPS_MOUSE32.219.3
KAPCB_MOUSE32.117.2
KAPCB_RAT32.117.2
GUX2_TRIRE32.118.2
MP2K2_RAT31.919.6
MSK1_TOBAC31.719
CSK2A_MAIZE31.516.6
KAPCA_RAT31.518.1
KAPCA_BOVIN31.518.1
F16P1_PIG31.416.2
MP2K2_MOUSE31.419.1
KAPCA_HUMAN31.318.1
KAPCA_PIG31.318.1
KAPCA_MOUSE31.117.9
SAHH_RAT3117
KAPCB_HUMAN3118
MAPK2_HUMAN3120.5
CP121_MYCTU30.820.1
Protein-Protein Interactions: