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Name:Prostaglandin G/H synthase 2
Uniprot name:PGH2_RAT
Accession Numbers:P35355 Q64379 Q925V4
EC-Number:1.14.99.1
Organism:Rat
Rattus norvegicus
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(Z)-5-(3,5-Di-tert-butyl-4-hydroxybenzylidene)-2-thioxo-thiazolidin-4-one1514885BindingDB-show
1-((4-Methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole115239PROMISCUOUSPMID 12773985show
1-Benzyl-1H-indazol-3-ol75181BindingDB-show
2-((1-Naphthalenyloxy)methyl)quinoline176149BindingDB-show
2-(3-(2-Quinolylmethoxy)phenylamino)benzoic acid128355BindingDB-show
2-(3-Pyridylmethyl)indazolinone129095BindingDB-show
2-(5-ethylpyridin-2-yl)benzimidazole49746BindingDB-show
2-Coumaranone68382BindingDB-show
3-Indazolinone81829BindingDB-show
3-Indazolinone, 2-methyl-590513BindingDB-show
3-Indazolinone, 2-phenyl-411519BindingDB-show
4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine47795BindingDB-show
4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide9865808PROMISCUOUSPMID 15096470show
5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole4306515PROMISCUOUS2 PMIDsshow
AC1NXG0X5804842BindingDB-show
AC1O1KQO6099176BindingDB-show
AC1P0KCL8122281BindingDB-show
ACRIDAN7106BindingDB-show
Ahr 10037132843BindingDB-show
alpha-(3,5-di-tert-Butyl-4-hydroxybenzylidene)gamma-butyrolactone6438990BindingDB-show
Baicalein5281605BindingDB-show
benzylidenemalononitrile (BMN) deriv. 102046PROMISCUOUS2 PMIDsshow
Butacortelone3672BindingDB-show
Celecoxib2662BindingDB-show
Celecoxib2662PROMISCUOUS4 PMIDsshow
CHEBI:64472844291838BindingDB-show
CHEBI:64691444347630BindingDB-show
CHEBI:64693344347632BindingDB-show
CHEBI:64694044347828BindingDB-show
CHEBI:64694444347833BindingDB-show
CHEBI:64696244347594BindingDB-show
CHEBI:64696744347610BindingDB-show
CHEBI:65248744377156BindingDB-show
CHEMBL1095019998276BindingDB-show
CHEMBL11143810044750BindingDB-show
CHEMBL1127209998758BindingDB-show
CHEMBL11273310067948BindingDB-show
CHEMBL11313844340012BindingDB-show
CHEMBL11321110449393BindingDB-show
CHEMBL11390810044272BindingDB-show
CHEMBL1215410424219BindingDB-show
CHEMBL1221910356827BindingDB-show
CHEMBL12219344347736BindingDB-show
CHEMBL12225544347761BindingDB-show
CHEMBL122349971422BindingDB-show
CHEMBL12237710314097BindingDB-show
CHEMBL1230214578544BindingDB-show
CHEMBL12321010066155BindingDB-show
CHEMBL12345910039814BindingDB-show
CHEMBL1237110471214BindingDB-show
CHEMBL1239510335925BindingDB-show
CHEMBL1248310425211BindingDB-show
CHEMBL1257210403436BindingDB-show
CHEMBL1280910313621BindingDB-show
CHEMBL1301313565415BindingDB-show
CHEMBL1318413565411BindingDB-show
CHEMBL1443313851286BindingDB-show
CHEMBL14670114578594BindingDB-show
CHEMBL14678614695704BindingDB-show
CHEMBL14885014578555BindingDB-show
CHEMBL14892244366100BindingDB-show
CHEMBL14896219764711BindingDB-show
CHEMBL14927814578565BindingDB-show
CHEMBL14944814578537BindingDB-show
CHEMBL14945144365847BindingDB-show
CHEMBL14994514578554BindingDB-show
CHEMBL15017014578549BindingDB-show
CHEMBL15071744366087BindingDB-show
CHEMBL15078314578547BindingDB-show
CHEMBL15080414578591BindingDB-show
CHEMBL15130944366083BindingDB-show
CHEMBL15143314578546BindingDB-show
CHEMBL15160844366043BindingDB-show
CHEMBL15184714791272BindingDB-show
CHEMBL15198719764723BindingDB-show
CHEMBL1590411726707BindingDB-show
CHEMBL15974010341834BindingDB-show
CHEMBL1604810247770BindingDB-show
CHEMBL16220222148991BindingDB-show
CHEMBL16232419041714BindingDB-show
CHEMBL1625729823987BindingDB-show
CHEMBL1627439803221BindingDB-show
CHEMBL16277644376580BindingDB-show
CHEMBL1628409822030BindingDB-show
CHEMBL16419444376581BindingDB-show
CHEMBL1643410022305BindingDB-show
CHEMBL168279972454BindingDB-show
CHEMBL1697710085620BindingDB-show
CHEMBL1709110380402BindingDB-show
CHEMBL17300944385978BindingDB-show
CHEMBL17313315518467BindingDB-show
CHEMBL1739399952337BindingDB-show
CHEMBL17450144385870BindingDB-show
CHEMBL1746169867925BindingDB-show
CHEMBL17468444386940BindingDB-show
CHEMBL17492244385887BindingDB-show
CHEMBL17497615518470BindingDB-show
CHEMBL17515015428612BindingDB-show
CHEMBL17515315461758BindingDB-show
CHEMBL17537244386627BindingDB-show
CHEMBL17599544386328BindingDB-show
CHEMBL17620015518471BindingDB-show
CHEMBL17666815428618BindingDB-show
CHEMBL17684419357230BindingDB-show
CHEMBL17694515461760BindingDB-show
CHEMBL17746215518472BindingDB-show
CHEMBL1777279844110BindingDB-show
CHEMBL17889644387163BindingDB-show
CHEMBL1793710455491BindingDB-show
CHEMBL26253915428617BindingDB-show
CHEMBL2642009868035BindingDB-show
CHEMBL26752414898745BindingDB-show
CHEMBL26873814898715BindingDB-show
CHEMBL26965414898718BindingDB-show
CHEMBL26965814898713BindingDB-show
CHEMBL27325314898737BindingDB-show
CHEMBL27358444325548BindingDB-show
CHEMBL27374314898710BindingDB-show
CHEMBL27394110336885BindingDB-show
CHEMBL27395610358656BindingDB-show
CHEMBL27433114898716BindingDB-show
CHEMBL27464018614299BindingDB-show
CHEMBL27464114898739BindingDB-show
CHEMBL27544510316610BindingDB-show
CHEMBL27590910065304BindingDB-show
CHEMBL27619814898735BindingDB-show
CHEMBL27691610063767BindingDB-show
CHEMBL27772110360396BindingDB-show
CHEMBL27824610452888BindingDB-show
CHEMBL28022610406427BindingDB-show
CHEMBL28429744282971BindingDB-show
CHEMBL28470613626845BindingDB-show
CHEMBL28576344283218BindingDB-show
CHEMBL28645021447325BindingDB-show
CHEMBL2870023684696BindingDB-show
CHEMBL29079721447336BindingDB-show
CHEMBL2915439907157BindingDB-show
CHEMBL29211814783933BindingDB-show
CHEMBL29232414459981BindingDB-show
CHEMBL29288414459992BindingDB-show
CHEMBL29329614545024BindingDB-show
CHEMBL29361714459989BindingDB-show
CHEMBL29368910595903BindingDB-show
CHEMBL29385814460014BindingDB-show
CHEMBL29391014783936BindingDB-show
CHEMBL29500844290598BindingDB-show
CHEMBL29524315027402BindingDB-show
CHEMBL29600613663098BindingDB-show
CHEMBL29654315027407BindingDB-show
CHEMBL29773314951358BindingDB-show
CHEMBL29867214951343BindingDB-show
CHEMBL29877614951365BindingDB-show
CHEMBL29979414951350BindingDB-show
CHEMBL30063714951345BindingDB-show
CHEMBL30113614951359BindingDB-show
CHEMBL30158614951360BindingDB-show
CHEMBL30199014951370BindingDB-show
CHEMBL30215510573844BindingDB-show
CHEMBL30220814783935BindingDB-show
CHEMBL30239414459996BindingDB-show
CHEMBL30241414783927BindingDB-show
CHEMBL30244110808991BindingDB-show
CHEMBL30283814460013BindingDB-show
CHEMBL30287914459997BindingDB-show
CHEMBL30319915713219BindingDB-show
CHEMBL30330314783940BindingDB-show
CHEMBL30336510500909BindingDB-show
CHEMBL30464714783931BindingDB-show
CHEMBL30466314783939BindingDB-show
CHEMBL30469014460017BindingDB-show
CHEMBL30469814460019BindingDB-show
CHEMBL30507610761358BindingDB-show
CHEMBL30613515634760BindingDB-show
CHEMBL30748414279613BindingDB-show
CHEMBL30759113577667BindingDB-show
CHEMBL31386044325331BindingDB-show
CHEMBL31699644325346BindingDB-show
CHEMBL32506510402845BindingDB-show
CHEMBL32531510018735BindingDB-show
CHEMBL32610810337379BindingDB-show
CHEMBL32843244325324BindingDB-show
CHEMBL32880144323887BindingDB-show
CHEMBL32917744323899BindingDB-show
CHEMBL32960644325536BindingDB-show
CHEMBL32978119900654BindingDB-show
CHEMBL33023144324069BindingDB-show
CHEMBL33027944324217BindingDB-show
CHEMBL33072244324215BindingDB-show
CHEMBL33106910108183BindingDB-show
CHEMBL33148910470426BindingDB-show
CHEMBL33152313611381BindingDB-show
CHEMBL33179344347789BindingDB-show
CHEMBL33210310266233BindingDB-show
CHEMBL33357910356777BindingDB-show
CHEMBL33414044347793BindingDB-show
CHEMBL3373413626849BindingDB-show
CHEMBL3395744283242BindingDB-show
CHEMBL3395921447333BindingDB-show
CHEMBL3420711776419BindingDB-show
CHEMBL3426420289606BindingDB-show
CHEMBL3441044283182BindingDB-show
CHEMBL3457810443677BindingDB-show
CHEMBL3457944282972BindingDB-show
CHEMBL3464944282957BindingDB-show
CHEMBL3469810036570BindingDB-show
CHEMBL34705312292503BindingDB-show
CHEMBL34797514578564BindingDB-show
CHEMBL3489459823986BindingDB-show
CHEMBL34923344375321BindingDB-show
CHEMBL34924810252093BindingDB-show
CHEMBL34960019041674BindingDB-show
CHEMBL35072915039189BindingDB-show
CHEMBL3512944282947BindingDB-show
CHEMBL3517844283219BindingDB-show
CHEMBL352099882188BindingDB-show
CHEMBL3521749867333BindingDB-show
CHEMBL3531321447326BindingDB-show
CHEMBL35355344385993BindingDB-show
CHEMBL3542510399303BindingDB-show
CHEMBL3551144283221BindingDB-show
CHEMBL35601444366004BindingDB-show
CHEMBL35651014578590BindingDB-show
CHEMBL35684319764749BindingDB-show
CHEMBL35714114695706BindingDB-show
CHEMBL35936914578592BindingDB-show
CHEMBL3596910219952BindingDB-show
CHEMBL36659515428613BindingDB-show
CHEMBL36701019357231BindingDB-show
CHEMBL36814815518468BindingDB-show
CHEMBL36854615428611BindingDB-show
CHEMBL3686829802075BindingDB-show
CHEMBL3692529929521BindingDB-show
CHEMBL36984815428614BindingDB-show
CHEMBL40791644325567BindingDB-show
CHEMBL41050044290580BindingDB-show
CHEMBL41348214728537BindingDB-show
CHEMBL41702214951349BindingDB-show
CHEMBL41707310447836BindingDB-show
CHEMBL41755714460000BindingDB-show
CHEMBL41822744283220BindingDB-show
CHEMBL41851414460055BindingDB-show
CHEMBL41866514459990BindingDB-show
CHEMBL42586015518469BindingDB-show
CHEMBL4259315027396BindingDB-show
CHEMBL4314113663094BindingDB-show
CHEMBL43205444325574BindingDB-show
CHEMBL43328719815165BindingDB-show
CHEMBL4354569844094BindingDB-show
CHEMBL4359079822795BindingDB-show
CHEMBL43635214460016BindingDB-show
CHEMBL4414913663090BindingDB-show
CHEMBL4436544289779BindingDB-show
CHEMBL44482814460002BindingDB-show
CHEMBL4495710085579BindingDB-show
CHEMBL45123615634750BindingDB-show
CHEMBL4657113663102BindingDB-show
CHEMBL4687115027391BindingDB-show
CHEMBL4691213663093BindingDB-show
CHEMBL4716413663096BindingDB-show
CHEMBL4716513663097BindingDB-show
CHEMBL4722310382186BindingDB-show
CHEMBL4856810064410BindingDB-show
CHEMBL488149996757BindingDB-show
CHEMBL4924910337700BindingDB-show
CHEMBL508339796248BindingDB-show
CHEMBL535329907677BindingDB-show
CHEMBL5361014951371BindingDB-show
CHEMBL5380514951372BindingDB-show
CHEMBL541569928419BindingDB-show
CHEMBL5513314406216BindingDB-show
CHEMBL55733313663091BindingDB-show
CHEMBL5584414545017BindingDB-show
CHEMBL5974844303712BindingDB-show
CHEMBL5975614783942BindingDB-show
CHEMBL6013614459979BindingDB-show
CHEMBL6016544304131BindingDB-show
CHEMBL6049610667335BindingDB-show
CHEMBL6049814460004BindingDB-show
CHEMBL6049914783928BindingDB-show
CHEMBL6072510689295BindingDB-show
CHEMBL6073810641802BindingDB-show
CHEMBL6079014459983BindingDB-show
CHEMBL6079310598425BindingDB-show
CHEMBL6094914783938BindingDB-show
CHEMBL6099314783941BindingDB-show
CHEMBL6099414460010BindingDB-show
CHEMBL6106514460018BindingDB-show
CHEMBL6142214459991BindingDB-show
CHEMBL6173110548621BindingDB-show
CHEMBL6195214459987BindingDB-show
CHEMBL6210114459975BindingDB-show
CHEMBL6229114783943BindingDB-show
CHEMBL6257214459986BindingDB-show
CHEMBL6261614459982BindingDB-show
CHEMBL6261714460006BindingDB-show
CHEMBL6263210596025BindingDB-show
CHEMBL6269314459985BindingDB-show
CHEMBL6272310597905BindingDB-show
CHEMBL6277214460009BindingDB-show
CHEMBL6281744303969BindingDB-show
CHEMBL6287410689418BindingDB-show
CHEMBL6291614459998BindingDB-show
CHEMBL6292010571788BindingDB-show
CHEMBL629909886145BindingDB-show
CHEMBL6354614783929BindingDB-show
CHEMBL6405114460001BindingDB-show
CHEMBL6406414459999BindingDB-show
CHEMBL6407614460012BindingDB-show
CHEMBL6418210501621BindingDB-show
CHEMBL6430414460015BindingDB-show
CHEMBL6433714460008BindingDB-show
CHEMBL6434214783937BindingDB-show
CHEMBL6437014460027BindingDB-show
CHEMBL6439614460022BindingDB-show
CHEMBL6439914459994BindingDB-show
CHEMBL6440314460007BindingDB-show
CHEMBL6442214460011BindingDB-show
CHEMBL6443514459993BindingDB-show
CHEMBL6445814459984BindingDB-show
CHEMBL6449014459977BindingDB-show
CHEMBL645079907256BindingDB-show
CHEMBL6458510830786BindingDB-show
CHEMBL6473814460025BindingDB-show
CHEMBL6475910740533BindingDB-show
CHEMBL6476314460026BindingDB-show
CHEMBL6481344304951BindingDB-show
CHEMBL6482214460005BindingDB-show
CHEMBL6485814460023BindingDB-show
CHEMBL6489110597904BindingDB-show
CHEMBL6505019815160BindingDB-show
CHEMBL6513015713218BindingDB-show
CHEMBL6533010810762BindingDB-show
CHEMBL6543044305443BindingDB-show
CHEMBL6543144305444BindingDB-show
CHEMBL6553519815158BindingDB-show
CHEMBL7320523720688BindingDB-show
CHEMBL7329512901249BindingDB-show
CHEMBL7334823720687BindingDB-show
CHEMBL7482512901252BindingDB-show
CHEMBL7508315634744BindingDB-show
CHEMBL7544514279611BindingDB-show
CHEMBL7558113577668BindingDB-show
CHEMBL7564612901254BindingDB-show
CHEMBL7589623720686BindingDB-show
CHEMBL7612615634759BindingDB-show
CHEMBL7727513577662BindingDB-show
CHEMBL7826313577661BindingDB-show
CHEMBL805314898717BindingDB-show
CHEMBL808214898711BindingDB-show
CHEMBL8193910988736BindingDB-show
CHEMBL823114898722BindingDB-show
CHEMBL833514898740BindingDB-show
CHEMBL834514898736BindingDB-show
CHEMBL835514898720BindingDB-show
CHEMBL837444265197BindingDB-show
CHEMBL837714898733BindingDB-show
CHEMBL841514898714BindingDB-show
CHEMBL843014898734BindingDB-show
CHEMBL863814898738BindingDB-show
CHEMBL866814898712BindingDB-show
CHEMBL8978244324206BindingDB-show
CHEMBL9008744323889BindingDB-show
CHEMBL9012744324218BindingDB-show
CHEMBL9017144324214BindingDB-show
CHEMBL9017210089518BindingDB-show
CHEMBL9060344324004BindingDB-show
CHEMBL9066044324005BindingDB-show
CHEMBL9091944323991BindingDB-show
CHEMBL9100444325563BindingDB-show
CHEMBL9113910020168BindingDB-show
CHEMBL912519928359BindingDB-show
CHEMBL9127744324213BindingDB-show
CHEMBL9131444324204BindingDB-show
CHEMBL9131544324205BindingDB-show
CHEMBL9157744324226BindingDB-show
CHEMBL9159544324035BindingDB-show
CHEMBL9187944323898BindingDB-show
CHEMBL9194344323843BindingDB-show
CHEMBL9198114728536BindingDB-show
CHEMBL9198244325396BindingDB-show
CHEMBL9229944325537BindingDB-show
CHEMBL9236744324068BindingDB-show
CHEMBL9275844325568BindingDB-show
CHEMBL9304644325571BindingDB-show
CHEMBL9331044325573BindingDB-show
CHEMBL9359844325360BindingDB-show
CHEMBL9359944325361BindingDB-show
CHEMBL9367044325550BindingDB-show
CHEMBL9371219900666BindingDB-show
CHEMBL9404244325584BindingDB-show
CHEMBL9422044325549BindingDB-show
CHEMBL9436119900665BindingDB-show
CHEMBL9485110089129BindingDB-show
Ci 9876444394BindingDB-show
Clofurac68806BindingDB-show
CP 6624857946BindingDB-show
Darbufelone mesilate6439420BindingDB-show
DAZOXIBEN53001BindingDB-show
Demethylindomethacin159665BindingDB-show
DEXIBUPROFEN39912BindingDB-show
Dibenzoparathiazine7108BindingDB-show
Dichlofenac3033BindingDB-show
Diferaloylmethane969516PROMISCUOUSPMID 14634121show
Dinoprostone5280360PROMISCUOUSPMID 12020690show
Dinoprostone158PROMISCUOUSPMID 12020690show
Diphenylbutazone4781BindingDB-show
FAAH Inhibitor II1383884PROMISCUOUSPMID 17543306show
Flogovital4495PROMISCUOUS5 PMIDsshow
FLURBIPROFEN3394PROMISCUOUSPMID 15096470show
gamma-Mangostin5464078PROMISCUOUSPMID 15322259show
Indomethacin derivative, 2310810285BindingDB-show
Indomethacinum3715BindingDB-show
Ketoprophene3825PROMISCUOUSPMID 10929089show
L-748780127942BindingDB-show
Lificiguat5712PROMISCUOUSPMID 17401444show
Meclofenamate4037BindingDB-show
Methoxypropiocin156391BindingDB-show
N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide4553PROMISCUOUS5 PMIDsshow
N-Hydroxy-N-(m-(2-quinolinylmethoxy)phenyl)succinamic acid methyl ester129110BindingDB-show
N-methoxy-3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-one6438164BindingDB-show
N-Methyl-4-benzyloxyphenylacetohydroxamic acid129232BindingDB-show
NAFAZATROM42923BindingDB-show
Naproxen1302BindingDB-show
Nepafenac151075BindingDB-show
NORDIHYDROGUAIARETIC ACID4534BindingDB-show
Nordihyolroguaiaretic acid71398BindingDB-show
NSC34822411523BindingDB-show
NSC512755350589BindingDB-show
NSC692765392401BindingDB-show
Oprea1_76082112658323BindingDB-show
Oxametacine33675BindingDB-show
p-Isobutylhydratropohydroxamic acid68704BindingDB-show
Phenazox23665728BindingDB-show
Phenazoxine67278BindingDB-show
Phenidone7090BindingDB-show
Piroxicam5280452BindingDB-show
REBAMIPIDE5042PROMISCUOUSPMID 11046075show
RITOLUKAST60539BindingDB-show
Rofecoxib5090BindingDB-show
Rofecoxib5090PROMISCUOUSPMID 12654342show
Romazarit71321BindingDB-show
Rosigilitazone77999PROMISCUOUS2 PMIDsshow
Sodium meclophenamate4038BindingDB-show
Sodium trinitrobenzenesulphonate11045PROMISCUOUSPMID 17943250show
TEPOXALIN59757BindingDB-show
Tomelukast3969BindingDB-show
WY 493533081197BindingDB-show
WY 49451130030BindingDB-show
Xanthaurine5280343BindingDB-show
Synonyms:
COX-2
Cyclooxygenase-2
PGH synthase 2
PGHS-2
PHS II
Prostaglandin G/H synthase 2
Prostaglandin H2 synthase 2
Prostaglandin-endoperoxide synthase 2
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PGH2_MOUSE98.296
PGH2_RABIT96.290.1
PGH2_CAVPO9588.7
PGH2_BOVIN9487.3
PGH2_HUMAN9386.4
PGH2_SHEEP9386.1
PGH1_SHEEP75.358.8
PGH1_MOUSE75.260.7
PGH1_RAT74.659.6
PGH1_HUMAN74.459.7
PGH1_RABIT74.259.8
Q8IZA9_HUMAN51.347.4
SPTC2_MOUSE30.716.2
CP4X1_HUMAN30.617.9
B5RQL8_BORRA30.515.8
DRTS_PLAFK30.315.2
SAP_HUMAN30.317.7
NIRS_PSEAE30.217.6
CP2A7_HUMAN30.218.2
NIRS_PARPN30.117.1
FRDA_SHEON30.117.6
TOXA_PSEAE3018.4
Q53G79_HUMAN29.716
ACVR1_HUMAN29.719
C1S_HUMAN29.518.7
CP4Z1_HUMAN29.416.5
Q93UV9_9BACI29.218
ASNS_HUMAN29.117.3
GATB_HUMAN2916.9
NDUS1_HUMAN28.916.6
Protein-Protein Interactions:
No data available