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Target Details

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Name:Prostaglandin G/H synthase 1
Uniprot name:PGH1_RAT
Accession Numbers:Q62731 Q63684 Q63921
EC-Number:1.14.99.1
Organism:Rat
Rattus norvegicus
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide9865808PROMISCUOUSPMID 15096470show
5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole4306515PROMISCUOUS3 PMIDsshow
benzylidenemalononitrile (BMN) deriv. 102046PROMISCUOUSPMID 10880385show
Celecoxib2662BindingDB-show
Celecoxib2662PROMISCUOUSPMID 11891194show
CHEMBL15974010341834BindingDB-show
CHEMBL16220222148991BindingDB-show
CHEMBL16232419041714BindingDB-show
CHEMBL1625729823987BindingDB-show
CHEMBL1627439803221BindingDB-show
CHEMBL16277644376580BindingDB-show
CHEMBL16419444376581BindingDB-show
CHEMBL17502710423951BindingDB-show
CHEMBL32880144323887BindingDB-show
CHEMBL32917744323899BindingDB-show
CHEMBL33023144324069BindingDB-show
CHEMBL33072244324215BindingDB-show
CHEMBL3489459823986BindingDB-show
CHEMBL34924810252093BindingDB-show
CHEMBL34960019041674BindingDB-show
CHEMBL3521749867333BindingDB-show
CHEMBL8978244324206BindingDB-show
CHEMBL9008744323889BindingDB-show
CHEMBL9012744324218BindingDB-show
CHEMBL9017144324214BindingDB-show
CHEMBL9017210089518BindingDB-show
CHEMBL9060344324004BindingDB-show
CHEMBL9066044324005BindingDB-show
CHEMBL9091944323991BindingDB-show
CHEMBL9113910020168BindingDB-show
CHEMBL912519928359BindingDB-show
CHEMBL9127744324213BindingDB-show
CHEMBL9131444324204BindingDB-show
CHEMBL9131544324205BindingDB-show
CHEMBL9157744324226BindingDB-show
CHEMBL9159544324035BindingDB-show
CHEMBL9187944323898BindingDB-show
CHEMBL9194344323843BindingDB-show
CHEMBL9236744324068BindingDB-show
DBPAA3080818BindingDB-show
Diferaloylmethane969516PROMISCUOUSPMID 14634121show
Dinoprostone5280360PROMISCUOUSPMID 12020690show
Dinoprostone158PROMISCUOUSPMID 12020690show
esflurbiprofen72099BindingDB-show
FAAH Inhibitor II1383884PROMISCUOUSPMID 17543306show
FLURBIPROFEN3394BindingDB-show
FLURBIPROFEN3394PROMISCUOUSPMID 15096470show
gamma-Mangostin5464078PROMISCUOUSPMID 15322259show
Indomethacin derivative, 2310810285BindingDB-show
Indomethacinum3715BindingDB-show
Ketoprophene3825PROMISCUOUSPMID 10929089show
L-748780127942BindingDB-show
N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide4553PROMISCUOUS4 PMIDsshow
pyranoprofen4888BindingDB-show
REBAMIPIDE5042PROMISCUOUSPMID 11046075show
Rofecoxib5090BindingDB-show
Rofecoxib5090PROMISCUOUSPMID 12654342show
Tarenflurbil92337BindingDB-show
Synonyms:
COX-1
Cyclooxygenase-1
PGH synthase 1
PGHS-1
PHS 1
Prostaglandin G/H synthase 1
Prostaglandin H2 synthase 1
Prostaglandin-endoperoxide synthase 1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PGH1_MOUSE97.895.2
PGH1_HUMAN92.987.5
PGH1_SHEEP91.784.9
PGH1_RABIT91.385.6
PGH2_BOVIN75.460.3
PGH2_RABIT74.860.3
PGH2_RAT74.659.6
PGH2_MOUSE74.459.7
PGH2_SHEEP74.259.2
PGH2_HUMAN73.658.2
PGH2_CAVPO73.558
Q8IZA9_HUMAN41.633.3
DLD_ECOLI3217.8
CP19A_RAT31.518.6
Q9JKC1_RAT31.217.8
TGFR2_HUMAN30.618
ACVR1_HUMAN30.617.9
P3H2_HUMAN30.518.7
CRY1_ARATH29.818
GYS2_HUMAN29.416.6
SPTC2_MOUSE29.318.7
IKKB_HUMAN29.216.6
CFAB_HUMAN29.217.3
C0LQ91_MOUSE28.917.3
PADI1_HUMAN28.917
ACES_TORCA28.916.2
FKBP4_HUMAN28.917.6
AMYB_BACCE28.818.1
HPSE_HUMAN28.717.3
A9JIG7_HUMAN28.717.5
Protein-Protein Interactions:
No data available