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Target Details

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Name:Prostaglandin G/H synthase 1
Uniprot name:PGH1_MOUSE
Accession Numbers:P22437
EC-Number:1.14.99.1
Organism:Mouse
Mus musculus
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1,3-di(2-thienyl)prop-2-en-1-one5463038BindingDB-show
1,3-di(furan-2-yl)prop-2-en-1-one5705708BindingDB-show
1,3-Diphenylisobenzothiophene282476BindingDB-show
1-pyridin-2-yl-3-thiophen-2-yl-prop-2-en-1-one6244095BindingDB-show
3-(2-furyl)-1-pyridin-2-yl-prop-2-en-1-one5854189BindingDB-show
3-(furan-2-yl)-1-(pyridin-3-yl)prop-2-en-1-one5915551BindingDB-show
4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide9865808PROMISCUOUSPMID 11956061show
5,7-diphenyl-2,3-dihydro-1H-pyrrolizine11032604BindingDB-show
5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole4306515PROMISCUOUS6 PMIDsshow
AA-516/314090511206916BindingDB-show
AC1OXDZ67946378BindingDB-show
Arachidonsaeure444899PROMISCUOUSPMID 12925531show
Arachidonyltrifluoromethane5280436PROMISCUOUSPMID 18641670show
Arthrocine1548887PROMISCUOUSPMID 11507063show
Benzylideneacetophenone637760BindingDB-show
Celecoxib2662BindingDB-show
Celecoxib2662PROMISCUOUSPMID 11936620show
CHEBI:64764644361026BindingDB-show
CHEBI:65235244361176BindingDB-show
CHEMBL13959110737046BindingDB-show
CHEMBL13972115521964BindingDB-show
CHEMBL1401679797804BindingDB-show
CHEMBL14017110737653BindingDB-show
CHEMBL14053323301367BindingDB-show
CHEMBL14072610497468BindingDB-show
CHEMBL1408049816911BindingDB-show
CHEMBL14087610592771BindingDB-show
CHEMBL14099110756729BindingDB-show
CHEMBL14129844361004BindingDB-show
CHEMBL14131210546816BindingDB-show
CHEMBL1420389860939BindingDB-show
CHEMBL1426509903294BindingDB-show
CHEMBL19135244400379BindingDB-show
CHEMBL19194111749869BindingDB-show
CHEMBL19267844400364BindingDB-show
CHEMBL19278911476820BindingDB-show
CHEMBL19481811328054BindingDB-show
CHEMBL19539144400419BindingDB-show
CHEMBL23615923635015BindingDB-show
CHEMBL23718223635014BindingDB-show
CHEMBL23718323634760BindingDB-show
CHEMBL23739123634759BindingDB-show
CHEMBL23759223634884BindingDB-show
CHEMBL23762623634643BindingDB-show
CHEMBL23781123634762BindingDB-show
CHEMBL23781323634763BindingDB-show
CHEMBL23802723634883BindingDB-show
CHEMBL23803123634764BindingDB-show
CHEMBL23803323634882BindingDB-show
CHEMBL31542111571968BindingDB-show
CHEMBL33537110493608BindingDB-show
CHEMBL34165213638864BindingDB-show
CHEMBL34331110494397BindingDB-show
CHEMBL3433399926403BindingDB-show
CHEMBL3437019796332BindingDB-show
CHEMBL3440859881981BindingDB-show
CHEMBL36339844400316BindingDB-show
CHEMBL36423844400333BindingDB-show
CHEMBL36496044400334BindingDB-show
CHEMBL39102023634761BindingDB-show
CHEMBL39111323636491BindingDB-show
CHEMBL39315923634642BindingDB-show
CHEMBL39316023634648BindingDB-show
CHEMBL39838223634644BindingDB-show
CHEMBL39838323634885BindingDB-show
CHEMBL39838423634886BindingDB-show
CHEMBL43814723635009BindingDB-show
CHEMBL44113223635010BindingDB-show
CHEMBL4416639883124BindingDB-show
CHEMBL45135824951165BindingDB-show
CHEMBL46227244569118BindingDB-show
CHEMBL46957425261943BindingDB-show
CHEMBL46978525261944BindingDB-show
CHEMBL47653624951166BindingDB-show
CHEMBL47736224951012BindingDB-show
CHEMBL47841524951011BindingDB-show
CHEMBL47905324899209BindingDB-show
CHEMBL47905424951163BindingDB-show
CHEMBL49286844569065BindingDB-show
CHEMBL49329744569103BindingDB-show
CHEMBL49349244569085BindingDB-show
CHEMBL49349344569087BindingDB-show
CHEMBL49349744569104BindingDB-show
CHEMBL49389844569044BindingDB-show
CHEMBL49470044569042BindingDB-show
CHEMBL49490444569043BindingDB-show
CHEMBL49490525141402BindingDB-show
CHEMBL49531844569067BindingDB-show
CHEMBL50544844569068BindingDB-show
CHEMBL51547824899975BindingDB-show
CHEMBL51628924951164BindingDB-show
CHEMBL51767524951013BindingDB-show
CHEMBL52216644569084BindingDB-show
CHEMBL52233344569102BindingDB-show
CHEMBL52338844569066BindingDB-show
CHEMBL52351544569086BindingDB-show
CHEMBL52355144569101BindingDB-show
CHEMBL52372044569025BindingDB-show
CHEMBL58908744818280BindingDB-show
CHEMBL58916644818282BindingDB-show
CHEMBL58916746229713BindingDB-show
CHEMBL58941046229714BindingDB-show
CHEMBL58981244818111BindingDB-show
CHEMBL58981323729118BindingDB-show
CHEMBL60016744818281BindingDB-show
CHEMBL60084444818112BindingDB-show
CHEMBL60223744818110BindingDB-show
CHEMBL60478146229731BindingDB-show
CHEMBL60516116757526BindingDB-show
CHEMBL60582044138220BindingDB-show
CHEMBL8483711506646BindingDB-show
CHEMBL8564910012992BindingDB-show
CHEMBL8602310036789BindingDB-show
CHEMBL8615311492422BindingDB-show
CHEMBL8741711535860BindingDB-show
CID 98606479860647BindingDB-show
CID 98835859883585BindingDB-show
CID 99298319929831BindingDB-show
DADHP155766BindingDB-show
Dichlofenac3033PROMISCUOUSPMID 12925531show
Diphenyl isoindoline606734BindingDB-show
Flogovital4495PROMISCUOUSPMID 12065685show
Imrecoxib11682175BindingDB-show
indomethacin phenethylamide4292BindingDB-show
Indomethacinum3715BindingDB-show
Merck Frosst Tricyclic127923PROMISCUOUSPMID 18292081show
Mofezolac4237PROMISCUOUSPMID 14991580show
N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide4553BindingDB-show
NSC1109365376088BindingDB-show
NSC6577635467683BindingDB-show
NSC7985354119BindingDB-show
Rofecoxib5090BindingDB-show
Rofecoxib5090PROMISCUOUSPMID 12566300show
ZINC040106565338978BindingDB-show
Synonyms:
COX-1
Cyclooxygenase-1
PGH synthase 1
PGHS-1
PHS 1
Prostaglandin G/H synthase 1
Prostaglandin H2 synthase 1
Prostaglandin-endoperoxide synthase 1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PGH1_RAT97.895.2
PGH1_HUMAN9489.4
PGH1_SHEEP92.586.5
PGH1_RABIT91.987
PGH2_BOVIN76.260.9
PGH2_RABIT75.561.2
PGH2_SHEEP75.459.9
PGH2_RAT75.260.7
PGH2_MOUSE7560.9
PGH2_CAVPO74.860
PGH2_HUMAN74.860.1
Q8IZA9_HUMAN41.834
TGFR2_HUMAN30.817.9
C8T4E0_KLEPR30.316.2
GLGS_SOLTU3016.6
GYS2_HUMAN29.916.9
CRY1_ARATH29.918.4
PYRG1_HUMAN29.819.1
PERM_HUMAN29.718.4
CPT2_RAT29.618.4
CSLB_PEDHD29.417.4
LONB_METJA29.216.3
Q8RBX6_THETN29.115.1
Q53ET4_HUMAN28.917.2
AMYB_BACCE28.818.7
GLYM_HUMAN28.616.7
MASP2_RAT28.617.2
SRC_RAT28.517.5
COCE_RHOSM28.516.4
Q8N1A5_HUMAN28.416.8
Protein-Protein Interactions:
No data available