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Target Details

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Name:Prostaglandin E synthase 2
Uniprot name:PGES2_HUMAN
Accession Numbers:Q53EW9 Q5SYV6 Q96GI0 Q96GL2 Q9H7Z7
EC-Number:5.3.99.3
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
Amoglandin5280363SuperTarget-show
Arthrocine1548887PROMISCUOUSPMID 11029586show
CHEMBL17820744389574BindingDB-show
CHEMBL17839044389925BindingDB-show
CHEMBL17902619914713BindingDB-show
CHEMBL18061744390943BindingDB-show
CHEMBL18065011526708BindingDB-show
CHEMBL18071844390220BindingDB-show
CHEMBL18084644390555BindingDB-show
CHEMBL18091944389649BindingDB-show
CHEMBL18123644390083BindingDB-show
CHEMBL18139044389535BindingDB-show
CHEMBL18172844390835BindingDB-show
CHEMBL18179244390723BindingDB-show
CHEMBL18183644390366BindingDB-show
CHEMBL18198644389542BindingDB-show
CHEMBL18203244390722BindingDB-show
CHEMBL18209244390282BindingDB-show
CHEMBL18215344389950BindingDB-show
CHEMBL18359644391283BindingDB-show
CHEMBL18387844391207BindingDB-show
CHEMBL36011444389720BindingDB-show
CHEMBL36074244389930BindingDB-show
CHEMBL36224244390610BindingDB-show
CHEMBL36266344389592BindingDB-show
CHEMBL36267544390496BindingDB-show
CHEMBL36283644390875BindingDB-show
CHEMBL36781744390119BindingDB-show
CHEMBL36824144390981BindingDB-show
CHEMBL36952544390653BindingDB-show
CHEMBL42605444390020BindingDB-show
CHEMBL48390011705274BindingDB-show
CHEMBL55514714591236BindingDB-show
CHEMBL56540616730275BindingDB-show
Dinoprostone5280360PROMISCUOUS2 PMIDsshow
Dinoprostone158PROMISCUOUS2 PMIDsshow
N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide4553PROMISCUOUSPMID 11029586show
Rofecoxib5090PROMISCUOUSPMID 14558087show
S1560_Selleck16070041BindingDB-show
Sulindac sulfide5352624PROMISCUOUSPMID 11029586show
Tocris-13113651377BindingDB-show
Tocris-1698122070BindingDB-show
Synonyms:
Microsomal prostaglandin E synthase 2
mPGES-2
Prostaglandin E synthase 2
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PDXK_SHEEP33.518.5
B4GT1_BOVIN33.319.3
PDXK_MOUSE32.918.6
KAPCG_HUMAN32.817.3
P83817_THETH32.515.9
BIOF_ECOLI32.518.6
NDUA9_HUMAN32.419
Q4W8W1_HUMAN32.217.9
SUFS_ECOLI32.219.4
Q8GN86_9BURK32.219.6
CSK_HUMAN32.218.8
Q49AK1_HUMAN31.919.4
PHR_THET831.919.7
IDH3B_RAT31.619.7
ACAD8_HUMAN31.619.3
GMDS_HUMAN31.517.5
IDH3B_HUMAN31.319.9
Q7Z471_HUMAN31.316.1
MP2K4_HUMAN31.118.4
PHHY_PSEFL3118.7
PHHY_PSEAE3118.7
ACADS_HUMAN3117.6
P5CR2_HUMAN30.917.3
LEU3_THIFE30.919.7
IDH3G_HUMAN30.718.8
GUNC_CLOSF30.715.1
AMPP_ECOLI30.519.4
ACADM_PIG30.519.6
RDH14_HUMAN30.517.8
Q96NU8_HUMAN30.418.4
Protein-Protein Interactions: