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Target Details

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Name:High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Uniprot name:PDE9A_HUMAN
Accession Numbers:B2RBI5 O75490 O75491 O76083 O95225 Q86SF7 Q86SI6 Q86SJ3 Q86WN3 Q86WN4 Q86WN5 Q86WN6 Q86WN7 Q86WN8 Q86WN9 Q86WP0
EC-Number:3.1.4.35
Organism:Homo sapiens
Human
PDB IDs:2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(R,S)-Mesopram9903410BindingDB-show
BAY-73-669146881198BindingDB-show
BAY-73-669146881199BindingDB-show
CHEMBL108537423624262BindingDB-show
CHEMBL108611024802717BindingDB-show
CHEMBL20090611438405BindingDB-show
CHEMBL20444918734933BindingDB-show
CHEMBL37310211547485BindingDB-show
CHEMBL45636823654252BindingDB-show
CHEMBL45721625179287BindingDB-show
CHEMBL45829825147798BindingDB-show
CHEMBL51427725179478BindingDB-show
CHEMBL55105211993169BindingDB-show
CHEMBL56566744607515BindingDB-show
CHEMBL56630044607348BindingDB-show
CHEMBL56747011992634BindingDB-show
CHEMBL57251725116996BindingDB-show
CHEMBL57274725116764BindingDB-show
CHEMBL57293421830891BindingDB-show
CHEMBL57444944607345BindingDB-show
CHEMBL57574544607178BindingDB-show
CHEMBL57577544607344BindingDB-show
CHEMBL57579025116768BindingDB-show
CHEMBL57579125116765BindingDB-show
CHEMBL57695244607177BindingDB-show
CHEMBL57803344607346BindingDB-show
CHEMBL58285644607343BindingDB-show
CHEMBL58306444607347BindingDB-show
CHEMBL58391425116766BindingDB-show
Cilomilast151170BindingDB-show
Erythro-9-(2 Hydroxy 3-Nonyl)Adenine149790BindingDB-show
FILAMINAST9578243BindingDB-show
GAMMA-GLUTAMYL[S-(2-IODOBENZYL)CYSTEINYL]GLYCINE447108DrugBank-show
Isobutylmethylxanthine3758BindingDB-show
Piclamilast154575BindingDB-show
Roflumilast449193BindingDB-show
ROLIPRAM5092BindingDB-show
Sildenafil5212BindingDB-show
Tadalafil110635BindingDB-show
Vardenafil110634BindingDB-show
zaprinast5722BindingDB-show
Zardaverine5723BindingDB-show
Synonyms:
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PDE4C_HUMAN3921.9
PDE4B_HUMAN38.921.7
PDE7A_HUMAN36.722.5
PDE1B_HUMAN34.420.1
PDE4D_MOUSE32.720
PDE6C_BOVIN32.417.6
DNLJ_ENTFA3216.3
LOX5_HUMAN3217.1
FUS_NDVD31.916.9
HSP82_YEAST31.617.3
ACV1B_HUMAN31.319.5
CHEA_THEMA31.217.2
THSA_THEK13117.6
KYNU_RAT30.915.4
DLD_ECOLI30.815.7
PDE10_HUMAN30.717.4
PDE4D_HUMAN30.718.5
SYK_HUMAN30.417.6
PDE10_RAT30.318.2
PDE7B_HUMAN30.317.4
TOP6B_SULSH3015.3
GCYB2_HUMAN3015.4
GDIA_BOVIN3017.2
SYFA_HUMAN29.918.2
HEXB_HUMAN29.918.3
CNX1_ARATH29.819.1
MCM6_HUMAN29.818.4
CP4FC_HUMAN29.615.8
UD2B4_HUMAN29.216.3
MALQ_THELI29.216.5
Protein-Protein Interactions: