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Target Details

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Name:cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Uniprot name:PDE4D_HUMAN
Accession Numbers:O43433 Q08499 Q13549 Q13550 Q13551 Q7Z2L8 Q8IV84 Q8IVA9 Q8IVD2 Q8IVD3 Q96HL4 Q9HCX7
EC-Number:3.1.4.17
Organism:Homo sapiens
Human
PDB IDs:1E9K 1MKD 1OYN 1PTW 1Q9M 1TB7 1TBB 1XOM 1XON 1XOQ 1XOR 1Y2B 1Y2C 1Y2D 1Y2E 1Y2K 1ZKN 2FM0 2FM5 2PW3 2QYN 3IAK
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
()-oxazepam hemisuccinate sodium salt46881323BindingDB-show
(R)-ROLIPRAM448055DrugBank-show
185954-27-29896267BindingDB-show
4-(5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl)-N-(2-dimethylaminoeth6918642BindingDB-show
7-(5-cyclohexylimino-4-methyl-1,3,4-thiadiazol-2-yl)quinazolin-4-amine6918791BindingDB-show
8-chloro-5-(2-hydroxyethoxy)spiro[1,3-dihydroquinazoline-4,1'-cyclohexane]6918799BindingDB-show
8-chloro-5-(2-morpholin-4-ylethoxy)spiro[1,3-dihydroquinazoline-4,1'-cyclo6918800BindingDB-show
AC1MVTY73713518BindingDB-show
AC1N657H4254532BindingDB-show
AC1NGCW44672917BindingDB-show
AC1NGCW74672918BindingDB-show
AC1OCFOD6918641BindingDB-show
AC1OCFPT6918667BindingDB-show
AC1OCFPV6918668BindingDB-show
AC1OCFW16918792BindingDB-show
AC1OCFW76918795BindingDB-show
AC1OCFW96918796BindingDB-show
AC1OCFWB6918797BindingDB-show
AC1OCFWD6918798BindingDB-show
Brevetoxin46881333BindingDB-show
CHEBI:64993844438583BindingDB-show
CHEMBL107711946881331BindingDB-show
CHEMBL107712146881332BindingDB-show
CHEMBL108678646881330BindingDB-show
CHEMBL108848446881334BindingDB-show
CHEMBL108968646884133BindingDB-show
CHEMBL108968746884134BindingDB-show
CHEMBL109001646830337BindingDB-show
CHEMBL109001746884135BindingDB-show
CHEMBL109003146884170BindingDB-show
CHEMBL109003246884171BindingDB-show
CHEMBL109004846884366BindingDB-show
CHEMBL109004946884367BindingDB-show
CHEMBL109037346830338BindingDB-show
CHEMBL109040546884368BindingDB-show
CHEMBL109070146884255BindingDB-show
CHEMBL109070246884256BindingDB-show
CHEMBL109070346884257BindingDB-show
CHEMBL109106246884298BindingDB-show
CHEMBL109144746884299BindingDB-show
CHEMBL109144846884300BindingDB-show
CHEMBL109145146884033BindingDB-show
CHEMBL109180746884094BindingDB-show
CHEMBL109209946884416BindingDB-show
CHEMBL109214246884095BindingDB-show
CHEMBL109216546884096BindingDB-show
CHEMBL109216646884097BindingDB-show
CHEMBL109279446884216BindingDB-show
CHEMBL109307046884217BindingDB-show
CHEMBL109307146884218BindingDB-show
CHEMBL109309446884219BindingDB-show
CHEMBL109334746884136BindingDB-show
CHEMBL109402346884172BindingDB-show
CHEMBL122143446933992BindingDB-show
CHEMBL122361849865602BindingDB-show
CHEMBL122361949865603BindingDB-show
CHEMBL122362049865604BindingDB-show
CHEMBL122362149865605BindingDB-show
CHEMBL122368449865642BindingDB-show
CHEMBL122368549865643BindingDB-show
CHEMBL122368646933994BindingDB-show
CHEMBL122368746933993BindingDB-show
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CHEMBL125765549780549BindingDB-show
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CHEMBL125812411641556BindingDB-show
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CHEMBL125880649780548BindingDB-show
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CHEMBL19843244405507BindingDB-show
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CHEMBL26331121920233BindingDB-show
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CHEMBL35161310664015BindingDB-show
CHEMBL35190010810934BindingDB-show
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CHEMBL35989044394047BindingDB-show
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CHEMBL46628044574673BindingDB-show
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CHEMBL59952524775390BindingDB-show
CHEMBL59952624775661BindingDB-show
CHEMBL60046846231671BindingDB-show
CHEMBL60079124775942BindingDB-show
CHEMBL60098924776040BindingDB-show
CHEMBL60099024776042BindingDB-show
CHEMBL60204624775939BindingDB-show
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CHEMBL60473124775389BindingDB-show
CHEMBL60493024774844BindingDB-show
CHEMBL60494024776131BindingDB-show
CHEMBL60509646227309BindingDB-show
CHEMBL60514646232320BindingDB-show
CHEMBL60534024774840BindingDB-show
CHEMBL60535524775658BindingDB-show
CHEMBL60536224775941BindingDB-show
CHEMBL60593546227285BindingDB-show
CHEMBL60617124776039BindingDB-show
CHEMBL60621424775943BindingDB-show
CHEMBL60638646232011BindingDB-show
CHEMBL60826824775388BindingDB-show
CHEMBL778269799389BindingDB-show
CHEMBL9037523218492BindingDB-show
CHEMBL9155144324331BindingDB-show
CHEMBL915719995407BindingDB-show
CHEMBL9571544329630BindingDB-show
CHEMBL9597944329893BindingDB-show
CHEMBL9603444329894BindingDB-show
CHEMBL9603944329683BindingDB-show
CHEMBL9721344329685BindingDB-show
CHEMBL9721444329686BindingDB-show
CHEMBL9778544329640BindingDB-show
CHEMBL9781710322207BindingDB-show
CHEMBL9786644329613BindingDB-show
CHEMBL9866244329651BindingDB-show
CHEMBL9873044329668BindingDB-show
CHEMBL9910144329511BindingDB-show
CHEMBL9947044329482BindingDB-show
CID 1011956310119564BindingDB-show
CID 1011956310119563BindingDB-show
CID 1022970910301548BindingDB-show
CID 1101724111039077BindingDB-show
CID 1195346512000774BindingDB-show
CID 98534989853498BindingDB-show
CID 985349810232106BindingDB-show
Cilomilast151170BindingDB-show
Dihydroxypropyltheophylline3182DrugBank-show
Erythro-9-(2 Hydroxy 3-Nonyl)Adenine149790BindingDB-show
Ibudilast3671BindingDB-show
Muskeladenylsaeure6083DrugBank-show
NITD60944469321BindingDB-show
NPV9999276BindingDB-show
phthalazinone, 1922337182BindingDB-show
phthalazinone, 2022337167BindingDB-show
Piclamilast154575BindingDB-show
ROLIPRAM5092BindingDB-show
ROLIPRAM158758DrugBank-show
ROLIPRAM5092DrugBank-show
S2224_Selleck9818682BindingDB-show
Sildenafil5212BindingDB-show
Zardaverine5723BindingDB-show
Synonyms:
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
DPDE3
PDE43
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PDE4D_MOUSE77.776.8
PDE4C_HUMAN71.461.5
PDE4B_HUMAN67.660
PDE4A_HUMAN63.553.9
PDE6C_BOVIN3520.5
PDE1B_HUMAN33.419.8
PDE2A_HUMAN32.119.4
PDE5A_BOVIN31.719.2
PDE11_RAT31.618.6
PDE5A_HUMAN31.619.3
SYI1_STAAU31.116.7
DGKZ_RAT3117.8
Q9XSW7_PIG3120.1
PDE9A_HUMAN30.718.5
PDE5A_RAT30.618.4
GYS2_MOUSE30.417.3
PDE5A_CANFA30.418.8
KPCD1_HUMAN30.115.9
GYS1_MOUSE29.717.6
PDE2A_MOUSE29.717
PDE3B_HUMAN29.619.1
TRPV3_HUMAN29.616.1
AMPD2_HUMAN29.516.7
KPCD1_MOUSE29.515.8
HTPG_ECOLI29.517.5
PDE6A_CANFA29.316.9
KS6A5_HUMAN29.317.3
PDXD1_HUMAN29.316.8
PDE6A_BOVIN29.217.1
MCCA_HUMAN29.116.6
Protein-Protein Interactions: