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Target Details

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Name:cGMP-dependent 3',5'-cyclic phosphodiesterase
Uniprot name:PDE2A_HUMAN
Accession Numbers:O00408
EC-Number:3.1.4.17
Organism:Homo sapiens
Human
PDB IDs:1Z1L
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(2R,3S)-3-(6-aminopurin-9-yl)nonan-2-ol149784BindingDB-show
1,3-Dihydro-7,8-dimethyl-2H-imidazo(4,5-b)quinolin-2-one5487281BindingDB-show
1-(3-Chlorophenylamino)-4-phenylphthalazine1348BindingDB-show
2-morpholin-4-yl-8-phenylchromen-4-one3973BindingDB-show
2127431921274319BindingDB-show
4-CH2BzN-3MeOQ205964BindingDB-show
4436737744367377BindingDB-show
7-(4-(Phenylsulfonyl)butoxy)-1,3-dihydro-2H-imidazo(4,5-b)quinolin-2-one5492386BindingDB-show
AC1L1C2L1713BindingDB-show
Anagrelide Hydrochloride2182BindingDB-show
Antistenocardin3108BindingDB-show
AR-L 57BS156890BindingDB-show
Arthrocine1548887SuperTarget-show
Bio2_0006646610310BindingDB-show
Bufrolin72103BindingDB-show
CBDivE_0032813262417BindingDB-show
CHEBI:12096444272080BindingDB-show
CHEBI:19249144301879BindingDB-show
CHEBI:22604844316961BindingDB-show
CHEBI:64586744318704BindingDB-show
CHEBI:65035344267977BindingDB-show
CHEMBL10050310142576BindingDB-show
CHEMBL10067613936982BindingDB-show
CHEMBL10078413936979BindingDB-show
CHEMBL10124613936987BindingDB-show
CHEMBL108537423624262BindingDB-show
CHEMBL108611024802717BindingDB-show
CHEMBL13865811826119BindingDB-show
CHEMBL18389944391348BindingDB-show
CHEMBL20090611438405BindingDB-show
CHEMBL20444918734933BindingDB-show
CHEMBL2438510626842BindingDB-show
CHEMBL2449510579873BindingDB-show
CHEMBL2471510816641BindingDB-show
CHEMBL2475210232923BindingDB-show
CHEMBL2519210674875BindingDB-show
CHEMBL2634810650764BindingDB-show
CHEMBL28336010508072BindingDB-show
CHEMBL28650214099426BindingDB-show
CHEMBL2867644278378BindingDB-show
CHEMBL28739813059432BindingDB-show
CHEMBL3035844279839BindingDB-show
CHEMBL3036213233885BindingDB-show
CHEMBL3036714099444BindingDB-show
CHEMBL3036813233889BindingDB-show
CHEMBL3040214099427BindingDB-show
CHEMBL30492710471556BindingDB-show
CHEMBL3062314099432BindingDB-show
CHEMBL3090820146320BindingDB-show
CHEMBL3110514099446BindingDB-show
CHEMBL3111213233881BindingDB-show
CHEMBL31328214281012BindingDB-show
CHEMBL31346314280990BindingDB-show
CHEMBL31659913724742BindingDB-show
CHEMBL31739913936973BindingDB-show
CHEMBL31760415065161BindingDB-show
CHEMBL3176213233882BindingDB-show
CHEMBL31916615065159BindingDB-show
CHEMBL31994715065158BindingDB-show
CHEMBL32307113936969BindingDB-show
CHEMBL32814914281015BindingDB-show
CHEMBL33028015005579BindingDB-show
CHEMBL33067714281033BindingDB-show
CHEMBL36245110117650BindingDB-show
CHEMBL37096225273570BindingDB-show
CHEMBL37310211547485BindingDB-show
CHEMBL4195044286951BindingDB-show
CHEMBL42188514280991BindingDB-show
CHEMBL43179914281026BindingDB-show
CHEMBL44509844295018BindingDB-show
CHEMBL44846714099449BindingDB-show
CHEMBL45636823654252BindingDB-show
CHEMBL45721625179287BindingDB-show
CHEMBL45829825147798BindingDB-show
CHEMBL51427725179478BindingDB-show
CHEMBL55105211993169BindingDB-show
CHEMBL56747011992634BindingDB-show
CHEMBL5872813887375BindingDB-show
CHEMBL6169244301890BindingDB-show
CHEMBL672439995187BindingDB-show
CHEMBL672769994528BindingDB-show
CHEMBL778269799389BindingDB-show
CHEMBL806810446136BindingDB-show
CHEMBL8813610017729BindingDB-show
CHEMBL882189999105BindingDB-show
CHEMBL8826515005604BindingDB-show
CHEMBL8839514280999BindingDB-show
CHEMBL8844415005576BindingDB-show
CHEMBL8852514280992BindingDB-show
CHEMBL8876414281024BindingDB-show
CHEMBL8966014281000BindingDB-show
CHEMBL8967914281027BindingDB-show
CHEMBL9019515005584BindingDB-show
CHEMBL9023714281025BindingDB-show
CHEMBL9041414281011BindingDB-show
CHEMBL9060114280995BindingDB-show
CHEMBL9067715005594BindingDB-show
CHEMBL9080414281006BindingDB-show
CHEMBL9104414281023BindingDB-show
CHEMBL9122414280994BindingDB-show
CHEMBL9129515005571BindingDB-show
CHEMBL9135614281004BindingDB-show
CHEMBL9136814281016BindingDB-show
CHEMBL9142214281010BindingDB-show
CHEMBL9147815005585BindingDB-show
CHEMBL9152715005574BindingDB-show
CHEMBL9163414280996BindingDB-show
CHEMBL9183715005567BindingDB-show
CHEMBL9184314280998BindingDB-show
CHEMBL9226414281001BindingDB-show
CHEMBL9236314281018BindingDB-show
CHEMBL9493110406931BindingDB-show
CHEMBL9754610359339BindingDB-show
CHEMBL9792215065156BindingDB-show
CHEMBL9794644330659BindingDB-show
CHEMBL9816415065157BindingDB-show
CHEMBL9820813936981BindingDB-show
CHEMBL9826813936978BindingDB-show
CHEMBL9826915065146BindingDB-show
CHEMBL9837315065155BindingDB-show
CHEMBL9860410867033BindingDB-show
CHEMBL9873813936971BindingDB-show
CHEMBL9881213936989BindingDB-show
CHEMBL9885113936972BindingDB-show
CHEMBL9894320200511BindingDB-show
CHEMBL9911744330560BindingDB-show
CHEMBL9914413936986BindingDB-show
CHEMBL9976015065145BindingDB-show
CHEMBL9982015065160BindingDB-show
CI-9303021729BindingDB-show
CID 382432011826264BindingDB-show
CID 984410910982315BindingDB-show
CID 984410911003969BindingDB-show
Cilomilast151170BindingDB-show
Cordemcura3698BindingDB-show
E402123665864BindingDB-show
EHNA3206BindingDB-show
Erythro-9-(2 Hydroxy 3-Nonyl)Adenine149790BindingDB-show
Fenoximone53708BindingDB-show
Hydroxypropyltheophylline4977BindingDB-show
IMAZODAN55918BindingDB-show
Isobutylmethylxanthine3758BindingDB-show
Milrinone4197BindingDB-show
Papaverine Monohydrochloride4680BindingDB-show
Pseudotheophylline2153BindingDB-show
RO 20-17245087BindingDB-show
ROLIPRAM5092BindingDB-show
Sildenafil5212BindingDB-show
Sildenafil5212DrugBank-show
Sildenafil5212SuperTargetPMID 16813753show
Sulindac5352DrugBank-show
sulmazole5353BindingDB-show
Tadalafil110635BindingDB-show
TETRAHYDROBENXIMIDAZOLE14032753BindingDB-show
Vardenafil110634BindingDB-show
zaprinast5722BindingDB-show
ZINC00057347158961BindingDB-show
ZINC00057348158962BindingDB-show
Synonyms:
cGMP-dependent 3',5'-cyclic phosphodiesterase
CGS-PDE
cGSPDE
Cyclic GMP-stimulated phosphodiesterase
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PDE2A_MOUSE92.589.2
PDE5A_HUMAN43.826.4
PDE5A_BOVIN43.525.4
PDE5A_CANFA42.424.9
PDE10_RAT40.926.1
PDE11_RAT40.625.6
PDE10_HUMAN40.225.5
PDE5A_RAT39.823.7
PDE6B_BOVIN37.821.6
PDE6C_BOVIN36.922
PDE6B_CANFA35.921.6
PDE6A_BOVIN35.620.4
PDE6A_CANFA33.719.8
PDE4D_HUMAN32.119.4
Q9UPF8_HUMAN31.316.7
Q5VSF5_HUMAN31.316.7
P94182_9NOST30.617.1
Q12844_HUMAN30.519.1
PK3CA_MOUSE30.116.8
PLCL1_HUMAN3017.1
CTNB1_HUMAN3017.2
CTNB1_MOUSE3017.2
CSF1R_HUMAN29.916.8
Q59H41_HUMAN29.815.7
PGFRA_HUMAN29.714.8
PDE4C_HUMAN29.718
Q5VSF9_HUMAN29.715.4
Q53EM0_HUMAN29.716.8
Q8IW08_HUMAN29.716.8
Q5SUJ9_HUMAN29.716.8
Protein-Protein Interactions: