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Target Details

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Name:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Uniprot name:PDE10_HUMAN
Accession Numbers:Q6FHX1 Q9HCP9 Q9NTV4 Q9Y233 Q9Y5T1
EC-Number:3.1.4.17
3.1.4.35
Organism:Homo sapiens
Human
PDB IDs:1LRB 2OUN 2OUP 2OUQ 2OUR 2OUS 2OUU 2OUV 2OUY 2WEY 2ZMF
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
ALBB-00040725218869BindingDB-show
Antistenocardin3108DrugBank-show
Antistenocardin3108SuperTarget-show
CHEMBL108260824805203BindingDB-show
CHEMBL108282546831934BindingDB-show
CHEMBL108312724804871BindingDB-show
CHEMBL108313546831935BindingDB-show
CHEMBL108316324804536BindingDB-show
CHEMBL108316424804535BindingDB-show
CHEMBL108316724804699BindingDB-show
CHEMBL108316824804540BindingDB-show
CHEMBL108316924803388BindingDB-show
CHEMBL108326624803387BindingDB-show
CHEMBL108339924805202BindingDB-show
CHEMBL108345824803224BindingDB-show
CHEMBL108345946831671BindingDB-show
CHEMBL108346046831672BindingDB-show
CHEMBL108357624804539BindingDB-show
CHEMBL108371542623946BindingDB-show
CHEMBL108374424803385BindingDB-show
CHEMBL108374524804701BindingDB-show
CHEMBL108377524803543BindingDB-show
CHEMBL108377624804538BindingDB-show
CHEMBL108377724804537BindingDB-show
CHEMBL108400424805036BindingDB-show
CHEMBL108400524805034BindingDB-show
CHEMBL108400624805035BindingDB-show
CHEMBL108400724805204BindingDB-show
CHEMBL108401742624027BindingDB-show
CHEMBL108401824803223BindingDB-show
CHEMBL108416946831673BindingDB-show
CHEMBL108433446831933BindingDB-show
CHEMBL108444724802718BindingDB-show
CHEMBL108471346831932BindingDB-show
CHEMBL108496424802716BindingDB-show
CHEMBL108503924805030BindingDB-show
CHEMBL108505524805200BindingDB-show
CHEMBL108515124802884BindingDB-show
CHEMBL108531142630684BindingDB-show
CHEMBL108531242623948BindingDB-show
CHEMBL108537324803384BindingDB-show
CHEMBL108537423624262BindingDB-show
CHEMBL108537524803386BindingDB-show
CHEMBL108537624803389BindingDB-show
CHEMBL108540424803051BindingDB-show
CHEMBL108540524802722BindingDB-show
CHEMBL108540646831931BindingDB-show
CHEMBL108540742630799BindingDB-show
CHEMBL108540824802885BindingDB-show
CHEMBL108564624802721BindingDB-show
CHEMBL108610624805205BindingDB-show
CHEMBL108610724802719BindingDB-show
CHEMBL108611024802717BindingDB-show
CHEMBL108611124803050BindingDB-show
CHEMBL108611224803049BindingDB-show
CHEMBL108626242624218BindingDB-show
CHEMBL108626342624216BindingDB-show
CHEMBL108626442624219BindingDB-show
CHEMBL108626524805199BindingDB-show
CHEMBL108632924803383BindingDB-show
CHEMBL108633024803227BindingDB-show
CHEMBL108635224802891BindingDB-show
CHEMBL19569644400409BindingDB-show
CHEMBL20090611438405BindingDB-show
CHEMBL20444918734933BindingDB-show
CHEMBL24559211641069BindingDB-show
CHEMBL24570911635020BindingDB-show
CHEMBL24571011613446BindingDB-show
CHEMBL24573744440404BindingDB-show
CHEMBL24578811655421BindingDB-show
CHEMBL24593744440405BindingDB-show
CHEMBL24593844440407BindingDB-show
CHEMBL24593944440408BindingDB-show
CHEMBL24598411525659BindingDB-show
CHEMBL24614111634505BindingDB-show
CHEMBL24614211641566BindingDB-show
CHEMBL24614344440410BindingDB-show
CHEMBL24634444440415BindingDB-show
CHEMBL24634544440416BindingDB-show
CHEMBL24656444440359BindingDB-show
CHEMBL24679811576116BindingDB-show
CHEMBL24679944440389BindingDB-show
CHEMBL24715944440391BindingDB-show
CHEMBL24736444440395BindingDB-show
CHEMBL24777744440369BindingDB-show
CHEMBL24777844440370BindingDB-show
CHEMBL24797344440373BindingDB-show
CHEMBL24805844440399BindingDB-show
CHEMBL24805944440401BindingDB-show
CHEMBL24837911504190BindingDB-show
CHEMBL24838011698194BindingDB-show
CHEMBL24969144441827BindingDB-show
CHEMBL24993344441840BindingDB-show
CHEMBL25013716727125BindingDB-show
CHEMBL25110744441833BindingDB-show
CHEMBL37310211547485BindingDB-show
CHEMBL39136411533673BindingDB-show
CHEMBL39218344440392BindingDB-show
CHEMBL39364611590899BindingDB-show
CHEMBL39444244440418BindingDB-show
CHEMBL39520511720710BindingDB-show
CHEMBL39609444440406BindingDB-show
CHEMBL39712944440363BindingDB-show
CHEMBL39760044440397BindingDB-show
CHEMBL39777444440403BindingDB-show
CHEMBL39929844441825BindingDB-show
CHEMBL39938511635241BindingDB-show
CHEMBL39969044441802BindingDB-show
CHEMBL40097644441831BindingDB-show
CHEMBL40118624180492BindingDB-show
CHEMBL40134544441837BindingDB-show
CHEMBL4020011742611BindingDB-show
CHEMBL43702044441829BindingDB-show
CHEMBL43718344440409BindingDB-show
CHEMBL43904344440367BindingDB-show
CHEMBL43957244440400BindingDB-show
CHEMBL44095411512099BindingDB-show
CHEMBL58391425116766BindingDB-show
Erythro-9-(2 Hydroxy 3-Nonyl)Adenine149790BindingDB-show
Papaverine Monohydrochloride4680BindingDB-show
ROLIPRAM5092BindingDB-show
SCH-3515919802841BindingDB-show
Sildenafil5212BindingDB-show
Tadalafil110635BindingDB-show
Vardenafil110634BindingDB-show
zaprinast5722BindingDB-show
Synonyms:
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PDE10_RAT95.292.6
PDE5A_RAT45.227.9
PDE11_RAT43.726
PDE5A_HUMAN43.627.4
PDE5A_BOVIN43.227.1
PDE5A_CANFA42.626.9
PDE6C_BOVIN41.324.2
PDE6B_CANFA41.224
PDE2A_MOUSE41.126
PDE6B_BOVIN40.624.4
PDE6A_CANFA40.423.5
PDE2A_HUMAN40.225.5
PDE6A_BOVIN39.323.8
PDE4B_HUMAN33.318
PDE4C_HUMAN32.219.4
ENPL_CANFA3218.6
PDE4D_MOUSE31.817.8
P94182_9NOST31.217.3
RFCS_PYRFU30.817
SKY1_YEAST30.715.9
PDE9A_HUMAN30.717.4
Q9XSW7_PIG30.317.2
ENPL_HUMAN30.118
HXK1_RAT30.117.6
PYGL_HUMAN3016.2
GYRA_HAEIN29.815.7
STA5B_HUMAN29.817.8
AHPF_ECOLI29.517
DNLJ_ENTFA29.417.2
NEP_RAT29.414.9
Protein-Protein Interactions:
Uniprot nameSource
WDR3_HUMANPMID 16169070