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Target Details

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Name:High affinity nerve growth factor receptor
Uniprot name:NTRK1_HUMAN
Accession Numbers:B2R6T5 B7ZM34 P04629 P08119 Q15655 Q15656 Q5D056 Q5VZS2 Q7Z5C3 Q9UIU7
EC-Number:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1HE7 1SHC 1WWA 1WWW 2IFG
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
7MP10062694BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
arylamide, 811654378BindingDB-show
AST-48711409972BindingDB-show
Bio2_0004136610353BindingDB-show
Bosutinib5328940BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:54743644560358BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL108870446222244BindingDB-show
CHEMBL109440824993189BindingDB-show
CHEMBL109587316223008BindingDB-show
CHEMBL122163346934144BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL125891311847343BindingDB-show
CHEMBL127023024809764BindingDB-show
CHEMBL15089410275001BindingDB-show
CHEMBL1721799943464BindingDB-show
CHEMBL1724329926067BindingDB-show
CHEMBL1734819944269BindingDB-show
CHEMBL17532144386338BindingDB-show
CHEMBL1764879858662BindingDB-show
CHEMBL1765449943465BindingDB-show
CHEMBL1768579827373BindingDB-show
CHEMBL18514016723801BindingDB-show
CHEMBL19560644400513BindingDB-show
CHEMBL19568144400566BindingDB-show
CHEMBL21226910181704BindingDB-show
CHEMBL25178944446916BindingDB-show
CHEMBL25179544446940BindingDB-show
CHEMBL25179644446941BindingDB-show
CHEMBL25363510226065BindingDB-show
CHEMBL25363644446917BindingDB-show
CHEMBL25384710301519BindingDB-show
CHEMBL25385544446918BindingDB-show
CHEMBL25385644446919BindingDB-show
CHEMBL25385744446921BindingDB-show
CHEMBL25385822170432BindingDB-show
CHEMBL25388121081523BindingDB-show
CHEMBL25405010165455BindingDB-show
CHEMBL25406044446922BindingDB-show
CHEMBL25406144446924BindingDB-show
CHEMBL25406244446925BindingDB-show
CHEMBL25426744446927BindingDB-show
CHEMBL25426844446929BindingDB-show
CHEMBL25426944446930BindingDB-show
CHEMBL25447844446931BindingDB-show
CHEMBL25447944446933BindingDB-show
CHEMBL25468844446935BindingDB-show
CHEMBL25468944446936BindingDB-show
CHEMBL25469044446937BindingDB-show
CHEMBL25489344446938BindingDB-show
CHEMBL25489444446939BindingDB-show
CHEMBL25489525032700BindingDB-show
CHEMBL27781710745853BindingDB-show
CHEMBL28822944284203BindingDB-show
CHEMBL2888169939328BindingDB-show
CHEMBL28881710626594BindingDB-show
CHEMBL28881810532168BindingDB-show
CHEMBL2903529917013BindingDB-show
CHEMBL2940219912413BindingDB-show
CHEMBL2970910604501BindingDB-show
CHEMBL36451344400620BindingDB-show
CHEMBL36469044400524BindingDB-show
CHEMBL36495844400664BindingDB-show
CHEMBL36558544400503BindingDB-show
CHEMBL3670299901444BindingDB-show
CHEMBL3689144284204BindingDB-show
CHEMBL36949044385063BindingDB-show
CHEMBL37049344400432BindingDB-show
CHEMBL37224944400720BindingDB-show
CHEMBL3752910770450BindingDB-show
CHEMBL3833810604778BindingDB-show
CHEMBL39847344446905BindingDB-show
CHEMBL39847444446906BindingDB-show
CHEMBL39861044443314BindingDB-show
CHEMBL40137444446920BindingDB-show
CHEMBL40334210157542BindingDB-show
CHEMBL40334344446926BindingDB-show
CHEMBL40334444446934BindingDB-show
CHEMBL42789244446932BindingDB-show
CHEMBL43040644446928BindingDB-show
CHEMBL43869710275928BindingDB-show
CHEMBL44243844446923BindingDB-show
CHEMBL56892211723489BindingDB-show
CHEMBL56972045375974BindingDB-show
CHEMBL57000225171665BindingDB-show
CHEMBL57625725171666BindingDB-show
CHEMBL57688723401001BindingDB-show
CHEMBL57698923400934BindingDB-show
CHEMBL57820145486156BindingDB-show
CHEMBL57860110246246BindingDB-show
CHEMBL59775446233287BindingDB-show
CHEMBL59922445139989BindingDB-show
CHEMBL59942845139991BindingDB-show
CHEMBL60348246228648BindingDB-show
CHEMBL60471210429593BindingDB-show
CHEMBL946789912410BindingDB-show
CHIR-26511656518BindingDB-show
CID 98096349809634BindingDB-show
CID 98523679852367BindingDB-show
CID 98742239874223BindingDB-show
CID 98746269874626BindingDB-show
CID 991701311621437BindingDB-show
CID 99375679937567BindingDB-show
CID 99382619938261BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
gw50745924208BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Imatinib Methansulfonate5291DrugBank-show
K1639_SIGMA3035817BindingDB-show
Kinome_248146224684BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_71446886323BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
nchembio.90-comp111715767BindingDB-show
Oprea1_8217122826530BindingDB-show
Oxindole-Based Inhibitor 916539118BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Trihydroxypropane753SuperTarget-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
High affinity nerve growth factor receptor
Neurotrophic tyrosine kinase receptor type 1
p140-TrkA
Trk-A
TRK1-transforming tyrosine kinase protein
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q99052_MOUSE3925.2
FGFR1_HUMAN38.524.4
FGFR1_MOUSE38.224.3
FGFR2_HUMAN37.923.4
FGFR3_HUMAN37.125
TYRO3_HUMAN35.622.6
ZAP70_HUMAN35.321.9
KIT_HUMAN34.723.3
Q6IQ28_HUMAN34.623.1
FGFR4_HUMAN34.523.2
FLT3_HUMAN34.322.3
DDR1_HUMAN34.324.1
CSF1R_HUMAN3422.4
EPHB1_HUMAN33.720.5
SRC_RSVSE32.919.3
KSYK_HUMAN3220.9
BRAF_HUMAN31.720.3
HCK_HUMAN31.519.7
Q9LCX5_THETH30.517.9
PGFRB_HUMAN30.318.9
ENPL_CANFA30.116.7
PGFRA_HUMAN3019.3
CSK_HUMAN3018.1
Q4G0E9_HUMAN29.817.5
Q6IPK9_HUMAN29.817.5
NDUS1_HUMAN29.617.6
ITK_HUMAN29.218
DPO1_THEAQ29.216.4
PDE11_RAT29.217.7
SYG_HUMAN29.118.1
Protein-Protein Interactions: