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Target Details

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Name:Azoreductase
Uniprot name:NQO1_HUMAN
Accession Numbers:B2R5Y9 P15559 Q86UK1
EC-Number:1.6.5.2
Organism:Homo sapiens
Human
PDB IDs:1D4A 1DXO 1GG5 1H66 1H69 1KBO 1KBQ 1QBG 2F1O
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
1,4-Diethoxybenzene67150BindingDB-show
1,4-Dimethoxyanthracene83107BindingDB-show
2,3',4,5',6-Biphenylpentol248349BindingDB-show
2,5-Diaziridinyl-3-(hydroxymethyl)- 6-methyl-1,4-benzoquinone394347DrugBank-show
2,6-Dimethyl-4H-pyran-4-one13862BindingDB-show
3-HYDROXYMETHYL-5-AZIRIDINYL-1METHYL-2-[1H-INDOLE-4,7-DIONE]-PROPANOL1667DrugBank-show
3Bz-4OHBzpyran2one455535BindingDB-show
4,3',5'-Tri-O-methylpiceatannol5385086BindingDB-show
4-Amino-chromen-2-one820807BindingDB-show
4-hydroxy-2H-chromen-2-one core, 1944520801BindingDB-show
4-hydroxy-2H-chromen-2-one core, 2044520802BindingDB-show
4-hydroxy-2H-chromen-2-one core, 2144520803BindingDB-show
4-hydroxy-2H-chromen-2-one core, 2244520804BindingDB-show
4-hydroxy-2H-chromen-2-one core, 2344520805BindingDB-show
439154439154DrugBank-show
5-METHOXY-1,2-DIMETHYL-3-(4-NITROPHENOXYMETHYL)INDOLE-4,7-DIONE4470790DrugBank-show
5-METHOXY-1,2-DIMETHYL-3-(PHENOXYMETHYL)INDOLE-4,7-DIONE4469805DrugBank-show
6-Methoxy-2-quinolinecarbonitrile230481BindingDB-show
AC1LAGZE468303BindingDB-show
AC1MD7CG2784880BindingDB-show
AC1N5PLP4199037BindingDB-show
Bisantrene hydrochloride5351322BindingDB-show
Bishydroxycoumarin653BindingDB-show
Bishydroxycoumarin653DrugBank-show
Bishydroxycoumarin653SuperTarget2 PMIDsshow
CHEBI:46926744420302BindingDB-show
CHEBI:46927844420308BindingDB-show
CHEBI:46928844420310BindingDB-show
CHEBI:46930044420315BindingDB-show
CHEBI:46932244420327BindingDB-show
CHEBI:46932344420328BindingDB-show
CHEBI:46939344420376BindingDB-show
CHEBI:46939444420377BindingDB-show
CHEBI:65361744420463BindingDB-show
CHEMBL12880456098228BindingDB-show
CHEMBL128816552941605BindingDB-show
CHEMBL2207879574067BindingDB-show
CHEMBL22083844420345BindingDB-show
CHEMBL22132544420298BindingDB-show
CHEMBL23718644435123BindingDB-show
CHEMBL56872044520795BindingDB-show
CHEMBL56916944520798BindingDB-show
CHEMBL56940644520792BindingDB-show
CHEMBL56941512853218BindingDB-show
CHEMBL56964044520797BindingDB-show
CHEMBL57033244520796BindingDB-show
CHEMBL57034944520799BindingDB-show
CHEMBL57105815444282BindingDB-show
CHEMBL57127244520807BindingDB-show
CHEMBL57128321477190BindingDB-show
CHEMBL57149644520790BindingDB-show
CHEMBL57216644520794BindingDB-show
CHEMBL57369344520800BindingDB-show
CHEMBL57611644520806BindingDB-show
CHEMBL57629344520793BindingDB-show
CHEMBL58293322114098BindingDB-show
CHEMBL58332344520791BindingDB-show
CHEMBL59263646231194BindingDB-show
CHEMBL59723046231192BindingDB-show
CHEMBL59744246231285BindingDB-show
CHEMBL59825346231284BindingDB-show
CHEMBL59887446231244BindingDB-show
CHEMBL59907246231245BindingDB-show
CHEMBL59907346231246BindingDB-show
CHEMBL59968646231193BindingDB-show
CHEMBL59968746231195BindingDB-show
CHEMBL59968846231243BindingDB-show
CHEMBL60902846231286BindingDB-show
CHEMBL61106746231191BindingDB-show
CHEMBL61108346231242BindingDB-show
ETHYL BISCOUMACETATE11047BindingDB-show
Methylnaphthoquinone4055DrugBank-show
Mitomycinum5746SuperTarget2 PMIDsshow
Mitomycinum231224SuperTarget2 PMIDsshow
Mono-tertiarybutylhydroquinone16043PROMISCUOUSPMID 15390080show
NSC1023595781276BindingDB-show
NSC1424219751BindingDB-show
NSC157307291778BindingDB-show
NSC158393292564BindingDB-show
NSC224124312765BindingDB-show
NSC275420321796BindingDB-show
NSC3536715384684BindingDB-show
NSC373939341568BindingDB-show
NSC373952341580BindingDB-show
NSC402836345301BindingDB-show
NSC4119195880BindingDB-show
NSC618201358258BindingDB-show
NSC621351359787BindingDB-show
NSC6284405387854BindingDB-show
NSC645820438560BindingDB-show
NSC645825438565BindingDB-show
NSC648420372797BindingDB-show
NSC6484225351406BindingDB-show
NSC6596925465716BindingDB-show
NSC667757381315BindingDB-show
NSC6826125469080BindingDB-show
NSC6826135469081BindingDB-show
NSC6826145469082BindingDB-show
NSC682616388131BindingDB-show
NSC686380389777BindingDB-show
NSC686383389780BindingDB-show
NSC6863845469329BindingDB-show
NSC686385389782BindingDB-show
NSC686386389783BindingDB-show
NSC686388389784BindingDB-show
NSC686391389787BindingDB-show
NSC686392389788BindingDB-show
NSC686393389789BindingDB-show
NSC686395389791BindingDB-show
NSC686396389792BindingDB-show
NSC6865815469347BindingDB-show
NSC689410391003BindingDB-show
NSC7341016528BindingDB-show
NSC99528264430BindingDB-show
PCBD20319BindingDB-show
Qingdainone3035728BindingDB-show
Tetramethylquinone68238DrugBank-show
Synonyms:
Azoreductase
DT-diaphorase
DTD
Menadione reductase
NAD(P)H dehydrogenase [quinone] 1
NAD(P)H:quinone oxidoreductase 1
Phylloquinone reductase
QR1
Quinone reductase 1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q53G81_HUMAN99.699.3
NQO1_MOUSE9286.5
NQO1_RAT91.285.4
NQO2_HUMAN50.738.6
Q9S1K0_STRPN35.219.1
FABI2_RHIME35.118.3
GSTO1_HUMAN34.421.2
PGDH_HUMAN33.721.8
LICT_BACSU33.516.5
O29280_ARCFU33.418.9
ILVE_ECOLI32.918.7
SUPH_ECOLI32.817.8
Q97NR6_STRPN32.716.5
Y796_METJA32.718.3
O06441_RHOSO32.619.9
AZOR_ECOLI32.417.1
NUSG_AQUAE32.219
LDH_GEOSE32.118.3
KANU_STAAU3218.4
SERC_BACAO31.918
HSD_STREX31.917.8
NADE_HELPY31.816.8
INHA_MYCTU31.817.6
FRP_VIBHA31.819.3
CTLA4_HUMAN31.816.6
AMPM_ECOLI31.719.5
BLAB_BACFR31.617.4
COMB_CLOAB31.517.4
P90613_TOXGO31.418.7
BIRA_ECOLI31.319.8
Protein-Protein Interactions: