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Target Details

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Name:cNOS
Uniprot name:NOS3_BOVIN
Accession Numbers:P29473
EC-Number:1.14.13.39
Organism:Bos taurus
Bovine
PDB IDs:1D0C 1D0O 1D1V 1D1W 1D1X 1D1Y 1DM6 1DM7 1DM8 1DMI 1DMJ 1DMK 1ED4 1ED5 1ED6 1FOI 1FOJ 1FOL 1FOO 1FOP 1I83 1NSE 1P6L 1P6M 1P6N 1Q2O 1RS8 1RS9 1ZZS 1ZZT 2G6O 2HX2 2NSE 3DQS 3DQT 3E7S 3NSE 4NSE 5NSE 6NSE 7NSE 8NSE 9NSE
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(5R)-4-methyl-5-pentyl-4,5-dihydro-3H-pyrrol-2-amine10398018BindingDB-show
1,2,4-TRIAZOLE-CARBOXAMIDINE3387240DrugBank-show
1-Benzyl-2-methylimidazole83699BindingDB-show
1-ethylsulfanyl-N'-phenylmethanimidamide347590DrugBank-show
1-methyl-7-nitroindazole151556BindingDB-show
1H-Indazol-7-amine88901BindingDB-show
1H-Indazol-7-ol21453601BindingDB-show
1H-Indazole-7-carbonitrile25022685BindingDB-show
1H-Indazole-7-carboxylic acid12639205BindingDB-show
2,4-DIAMINO-6-PHENYL-5,6,7,8,-TETRAHYDROPTERIDINE445109DrugBank-show
2-[3-(2-carbamimidoylsulfanylethyl)phenyl]ethylsulfanylmethanimidamide1331DrugBank-show
2-[4-(2-carbamimidoylsulfanylethyl)phenyl]ethylsulfanylmethanimidamide1337DrugBank-show
3-BROMO-7-NITROINDAZOLE1649BindingDB-show
3-BROMO-7-NITROINDAZOLE1649DrugBank-show
3HX16058621BindingDB-show
40027-64-324186467BindingDB-show
5,6-CYCLIC-TETRAHYDROPTERIDINE6323220DrugBank-show
52885375288537DrugBank-show
6-{[(3r,4r)-4-(2-{[2-(3-Fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-Yl]me46225774BindingDB-show
6-{[(3s,4s)-4-(2-{[2-(3-Fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-Yl]me42636915BindingDB-show
6S-5,6,7,8-TETRAHYDROBIOPTERIN6323235DrugBank-show
7-Iodo-1H-indazole16726525BindingDB-show
7-nitroindazole-2-carboximidamide1894DrugBank-show
7-Nitroisoindazole1893BindingDB-show
7-Nitroisoindazole1893DrugBank-show
7-Nitroisoindazole1893PROMISCUOUSPMID 7526799show
AC1LCVP8656914BindingDB-show
aminopyridine-pyrrolidine, 424850913BindingDB-show
Asymmetric dimethylarginine123831DrugBank-show
Athylenglykol174DrugBank-show
Benzophenanthridine alkaloid2703PROMISCUOUSPMID 7533140show
Benzophenanthridine alkaloid197810PROMISCUOUSPMID 7533140show
Benzophenanthridine alkaloid4501PROMISCUOUSPMID 7533140show
Canavanine439202DrugBank-show
CHEBI:16813744291051BindingDB-show
CHEBI:18734644299542BindingDB-show
CHEBI:18734723278155BindingDB-show
CHEBI:25290744326640BindingDB-show
CHEBI:25574410766216BindingDB-show
CHEBI:25578415547276BindingDB-show
CHEBI:25578910718613BindingDB-show
CHEBI:27507844336772BindingDB-show
CHEBI:27559344336958BindingDB-show
CHEBI:27576444337020BindingDB-show
CHEBI:27596844337117BindingDB-show
CHEBI:30831344350158BindingDB-show
CHEBI:30848844350240BindingDB-show
CHEBI:30851844350254BindingDB-show
CHEBI:30855144350271BindingDB-show
CHEBI:30855244350273BindingDB-show
CHEBI:55682344564446BindingDB-show
CHEBI:55682444564447BindingDB-show
CHEBI:64529244307159BindingDB-show
CHEBI:64539144307242BindingDB-show
CHEBI:64539744307408BindingDB-show
CHEBI:64540544307180BindingDB-show
CHEBI:64614944326868BindingDB-show
CHEBI:64615344326627BindingDB-show
CHEBI:64615544326625BindingDB-show
CHEBI:64615844326780BindingDB-show
CHEBI:64616844326816BindingDB-show
CHEBI:64619544326666BindingDB-show
CHEBI:64619744326664BindingDB-show
CHEBI:64620844326649BindingDB-show
CHEBI:64621044326718BindingDB-show
CHEBI:65121944307160BindingDB-show
CHEBI:65122744307243BindingDB-show
CHEBI:65127944307401BindingDB-show
CHEBI:65134944307178BindingDB-show
CHEBI:65136144307393BindingDB-show
CHEBI:65162444326623BindingDB-show
CHEBI:65182544326870BindingDB-show
CHEBI:66378245271554BindingDB-show
CHEBI:66380345271562BindingDB-show
CHEBI:66391545271614BindingDB-show
CHEMBL10052410498721BindingDB-show
CHEMBL10076110651023BindingDB-show
CHEMBL10104210840870BindingDB-show
CHEMBL10121411800991BindingDB-show
CHEMBL10176610650502BindingDB-show
CHEMBL10192644331525BindingDB-show
CHEMBL10389644331546BindingDB-show
CHEMBL10681544337005BindingDB-show
CHEMBL108685846880969BindingDB-show
CHEMBL108685946880970BindingDB-show
CHEMBL108774646880968BindingDB-show
CHEMBL122260749864878BindingDB-show
CHEMBL122260846846307BindingDB-show
CHEMBL122260949864879BindingDB-show
CHEMBL122261049864880BindingDB-show
CHEMBL122267549864917BindingDB-show
CHEMBL122267649864918BindingDB-show
CHEMBL122267749864919BindingDB-show
CHEMBL122267849864920BindingDB-show
CHEMBL122274549864953BindingDB-show
CHEMBL122274646935152BindingDB-show
CHEMBL122274749864954BindingDB-show
CHEMBL123038046907789BindingDB-show
CHEMBL123038146907790BindingDB-show
CHEMBL126910350899557BindingDB-show
CHEMBL126910450899558BindingDB-show
CHEMBL126910552940828BindingDB-show
CHEMBL126910652948091BindingDB-show
CHEMBL126915652949342BindingDB-show
CHEMBL127046049831165BindingDB-show
CHEMBL127611849837180BindingDB-show
CHEMBL127611952948360BindingDB-show
CHEMBL127612052949612BindingDB-show
CHEMBL127616752942929BindingDB-show
CHEMBL127687652942270BindingDB-show
CHEMBL127696552943506BindingDB-show
CHEMBL127696652947165BindingDB-show
CHEMBL127696752948375BindingDB-show
CHEMBL127705352947134BindingDB-show
CHEMBL127705452947135BindingDB-show
CHEMBL127705552944667BindingDB-show
CHEMBL127714152946777BindingDB-show
CHEMBL127714252941903BindingDB-show
CHEMBL127714352941904BindingDB-show
CHEMBL127723252946780BindingDB-show
CHEMBL127723352940723BindingDB-show
CHEMBL127732749837182BindingDB-show
CHEMBL127741949837185BindingDB-show
CHEMBL127742049837187BindingDB-show
CHEMBL127750849837282BindingDB-show
CHEMBL127750949837284BindingDB-show
CHEMBL127760149837286BindingDB-show
CHEMBL127760249837288BindingDB-show
CHEMBL127769352941638BindingDB-show
CHEMBL127769452941918BindingDB-show
CHEMBL127778649837388BindingDB-show
CHEMBL127778749837390BindingDB-show
CHEMBL127787052948929BindingDB-show
CHEMBL127795152948411BindingDB-show
CHEMBL127795252944737BindingDB-show
CHEMBL127803752942341BindingDB-show
CHEMBL127803852948423BindingDB-show
CHEMBL127813152949000BindingDB-show
CHEMBL127813252944743BindingDB-show
CHEMBL127813352941132BindingDB-show
CHEMBL127821752941110BindingDB-show
CHEMBL15258344368777BindingDB-show
CHEMBL15264544368846BindingDB-show
CHEMBL15445144368868BindingDB-show
CHEMBL1612979850719BindingDB-show
CHEMBL21610244417334BindingDB-show
CHEMBL21677044417331BindingDB-show
CHEMBL22639044423364BindingDB-show
CHEMBL22644544423365BindingDB-show
CHEMBL22644644423367BindingDB-show
CHEMBL22644744423368BindingDB-show
CHEMBL22644844423369BindingDB-show
CHEMBL22649944423371BindingDB-show
CHEMBL22821216220908BindingDB-show
CHEMBL26204010524594BindingDB-show
CHEMBL29584810870586BindingDB-show
CHEMBL29610211056403BindingDB-show
CHEMBL29709511119989BindingDB-show
CHEMBL29720710935782BindingDB-show
CHEMBL29737210426356BindingDB-show
CHEMBL31154144322476BindingDB-show
CHEMBL31289910851593BindingDB-show
CHEMBL31322810858252BindingDB-show
CHEMBL31730310523506BindingDB-show
CHEMBL31752144331486BindingDB-show
CHEMBL31865410531193BindingDB-show
CHEMBL32084144331545BindingDB-show
CHEMBL32988310634623BindingDB-show
CHEMBL34635044368785BindingDB-show
CHEMBL35748544368686BindingDB-show
CHEMBL37505644423374BindingDB-show
CHEMBL37589544423361BindingDB-show
CHEMBL37594344423366BindingDB-show
CHEMBL37614544423370BindingDB-show
CHEMBL38481544417316BindingDB-show
CHEMBL41974018356525BindingDB-show
CHEMBL42063710721313BindingDB-show
CHEMBL4209310935781BindingDB-show
CHEMBL42099615547277BindingDB-show
CHEMBL42728616058622BindingDB-show
CHEMBL43326011722865BindingDB-show
CHEMBL4393710447220BindingDB-show
CHEMBL4399711066357BindingDB-show
CHEMBL44299911023747BindingDB-show
CHEMBL44617144368773BindingDB-show
CHEMBL44697144592992BindingDB-show
CHEMBL4496410957845BindingDB-show
CHEMBL4502111088167BindingDB-show
CHEMBL45058325231660BindingDB-show
CHEMBL4511311131126BindingDB-show
CHEMBL4511910990090BindingDB-show
CHEMBL4513210903407BindingDB-show
CHEMBL45154144585510BindingDB-show
CHEMBL4524310086655BindingDB-show
CHEMBL45295644585508BindingDB-show
CHEMBL4544111758669BindingDB-show
CHEMBL45657916726526BindingDB-show
CHEMBL4691311034234BindingDB-show
CHEMBL46936644592417BindingDB-show
CHEMBL4697411011882BindingDB-show
CHEMBL47019344592351BindingDB-show
CHEMBL47926844570753BindingDB-show
CHEMBL47926944570757BindingDB-show
CHEMBL47927044570758BindingDB-show
CHEMBL47928044570846BindingDB-show
CHEMBL47946944570847BindingDB-show
CHEMBL47966644570880BindingDB-show
CHEMBL47966744570881BindingDB-show
CHEMBL48024744570692BindingDB-show
CHEMBL48025444570843BindingDB-show
CHEMBL48025544570844BindingDB-show
CHEMBL48025644570845BindingDB-show
CHEMBL48041844570883BindingDB-show
CHEMBL4807011823487BindingDB-show
CHEMBL48084044570837BindingDB-show
CHEMBL48103244570839BindingDB-show
CHEMBL48103324202627BindingDB-show
CHEMBL48141344570727BindingDB-show
CHEMBL48142044570690BindingDB-show
CHEMBL48146544570759BindingDB-show
CHEMBL48181544570760BindingDB-show
CHEMBL48181625210263BindingDB-show
CHEMBL48200344570684BindingDB-show
CHEMBL48220544570686BindingDB-show
CHEMBL48429744586039BindingDB-show
CHEMBL49958344586041BindingDB-show
CHEMBL50488312194801BindingDB-show
CHEMBL50801444570842BindingDB-show
CHEMBL51069244585511BindingDB-show
CHEMBL51213644592415BindingDB-show
CHEMBL51370244592416BindingDB-show
CHEMBL51674044585509BindingDB-show
CHEMBL51674144585512BindingDB-show
CHEMBL51676424990311BindingDB-show
CHEMBL51722144570755BindingDB-show
CHEMBL51799544570882BindingDB-show
CHEMBL51977244570841BindingDB-show
CHEMBL51978944570683BindingDB-show
CHEMBL52009944570691BindingDB-show
CHEMBL52077225210265BindingDB-show
CHEMBL52125444570688BindingDB-show
CHEMBL6668222646274BindingDB-show
CHEMBL8810744323742BindingDB-show
CHEMBL8816610378286BindingDB-show
CHEMBL881779860615BindingDB-show
CHEMBL8826710084004BindingDB-show
CHEMBL8866510825774BindingDB-show
CHEMBL8869610682300BindingDB-show
CHEMBL8945410489277BindingDB-show
CHEMBL912569994346BindingDB-show
CHEMBL9220811065659BindingDB-show
CHEMBL9249310084782BindingDB-show
CHEMBL966809842658BindingDB-show
CHEMBL9808610768934BindingDB-show
CHEMBL9838310671340BindingDB-show
CID 1059593310499986BindingDB-show
CID 1059593310595933BindingDB-show
CID 1071392910713929BindingDB-show
CID 1071392910570902BindingDB-show
CID 984284210499987BindingDB-show
CID 984284210523810BindingDB-show
CID 984284210667470BindingDB-show
D7P656915BindingDB-show
Dicaprylglyceride1323PROMISCUOUSPMID 7513644show
Dimethylarsinate167250DrugBank-show
Dimethylarsinate2513DrugBank-show
Dimethylarsino3034811DrugBank-show
dipeptide amide inhibitor I656910BindingDB-show
dipeptide amide inhibitor I656910DrugBank-show
Efetozole208911BindingDB-show
Essigsaeure176DrugBank-show
ethylselanylmethanimidamide449633DrugBank-show
ethylsulfanylmethanimidamide5139DrugBank-show
Glyoxaline795PROMISCUOUSPMID 7526799show
Hydroxyethylene derivative, 1024776426BindingDB-show
Hydroxyethylene derivative, 1124776427BindingDB-show
Hydroxyethylene derivative, 424776421BindingDB-show
Hydroxyethylene derivative, 524776422BindingDB-show
Hydroxyethylene derivative, 624776423BindingDB-show
Hydroxyethylene derivative, 724776424BindingDB-show
Hydroxyethylene derivative, 824776425BindingDB-show
Hydroxyethylene derivative, 923624983BindingDB-show
J1445259041BindingDB-show
JI224850786BindingDB-show
JI324798097BindingDB-show
JI424798098BindingDB-show
JI725021186BindingDB-show
Kinome_133344586040BindingDB-show
L-HOMOARGININE5288582DrugBank-show
L-nitroarginine440005BindingDB-show
L-nitroarginine440005DrugBank-show
N omega-Nitro-L-Arginine-Containing Dipeptide, 1656911BindingDB-show
N omega-Nitro-L-Arginine-Containing Dipeptide, 1656911DrugBank-show
N omega-Nitro-L-Arginine-Containing Dipeptide, 2656912BindingDB-show
N omega-Nitro-L-Arginine-Containing Dipeptide, 2656912DrugBank-show
N(G)-Iminoethylornithine107984DrugBank-show
N(omega)-hydroxyarginine123895DrugBank-show
N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE1433BindingDB-show
N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE1433DrugBank-show
N-(CHLOROPHENYL)-N'-HYDROXYGUANIDINE181426DrugBank-show
N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE446223DrugBank-show
Phenylimidazole81595PROMISCUOUSPMID 7526799show
Pirinixic acid5694PROMISCUOUSPMID 14751809show
propan-2-ylsulfanylmethanimidamide445319DrugBank-show
sFtHLPDISNmMP@15689DrugBank-show
Sklerofibrat39042PROMISCUOUSPMID 14751809show
Targinine132862BindingDB-show
TETRAHYDROBIOPTERIN44257DrugBank-show
tetrahydrobiopterin1125DrugBank-show
Synonyms:
cNOS
Constitutive NOS
EC-NOS
Endothelial NOS
eNOS
Nitric oxide synthase, endothelial
NOS type III
NOSIII
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
NOS3_PIG97.495.6
NOS3_HUMAN96.794.4
NOS3_MOUSE96.192.7
NOS3_RAT95.792.5
NOS2_BOVIN63.849.7
NOS2_HUMAN61.747.3
NOS2_MOUSE61.647
NOS2_RAT61.347.4
NOS2_CHICK60.945.4
NOS1_RAT60.748.2
NOS1_MOUSE60.648.3
NOS1_RABIT59.547.8
NOS1_HUMAN59.547.4
CPXB_BACME3421.1
JAK2_RAT28.717.2
JAK3_MOUSE28.417.1
SYIC_HUMAN28.316
SYI_THET828.117.1
NCPR_RABIT27.917.6
NOS2_RABIT27.821
FAK1_MOUSE27.816.8
RDRP_REOVD27.816.5
FAK1_HUMAN27.616.2
NCPR_HUMAN27.518
TAOK2_RAT27.518
Q43235_VICSA27.318
PSD1_HUMAN27.318.3
NCPR_RAT2717.4
ABL1_HUMAN26.816
Q59FK4_HUMAN26.616.1
Protein-Protein Interactions:
No data available