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Target Details

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Name:Inducible NO synthase
Uniprot name:NOS2_RAT
Accession Numbers:O35765 O35766 O60591 O60604 P97774 Q06518 Q63267 Q64005 Q64558
EC-Number:1.14.13.39
Organism:Rat
Rattus norvegicus
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol104895PROMISCUOUSPMID 11727767show
AC1L1GVT3863BindingDB-show
AC1L1I2J4395BindingDB-show
Acetovanillone2214PROMISCUOUSPMID 18001708show
Asiaticoside11954171PROMISCUOUSPMID 15643549show
benzylidenemalononitrile (BMN) deriv. 102046PROMISCUOUS2 PMIDsshow
BMY 7378 dihydrochloride2419PROMISCUOUSPMID 16043851show
Bromochlorotrifluoroethane3562PROMISCUOUSPMID 11506125show
bromophenacylbromide7454PROMISCUOUSPMID 15777770show
CHEMBL12773922133392BindingDB-show
CHEMBL23365210452321BindingDB-show
CHEMBL23365344430634BindingDB-show
CHEMBL23365544430637BindingDB-show
CHEMBL23385710411355BindingDB-show
CHEMBL41279710068818BindingDB-show
Dextrone15939PROMISCUOUSPMID 18985485show
Diethylnitrosoamine5921PROMISCUOUSPMID 17418998show
Diferaloylmethane969516PROMISCUOUSPMID 14634121show
Dimethyl methoxycarbonylpropenyl phosphate5355863PROMISCUOUSPMID 17438462show
Fasudil hydrochloride3547PROMISCUOUSPMID 17111028show
Fasudil hydrochloride163751PROMISCUOUSPMID 17111028show
Genisterin5280961PROMISCUOUSPMID 17881116show
Isoflurane3763PROMISCUOUSPMID 12105371show
ISOFLURANE4369440PROMISCUOUSPMID 12105371show
L-N6-(1-Iminoethyl)lysine hydrochloride11957582BindingDB-show
Lificiguat5712PROMISCUOUSPMID 17401444show
Nitro-L-arginine4367BindingDB-show
Oximetazolinum4636PROMISCUOUSPMID 11028657show
Pyrrolidinedithiocarbamate65351PROMISCUOUS3 PMIDsshow
Rosigilitazone77999PROMISCUOUSPMID 14709329show
S-Methylisothiopseudouronium5142PROMISCUOUS5 PMIDsshow
Semaxinib5329098PROMISCUOUSPMID 15064225show
SIMVASTATIN54454PROMISCUOUS2 PMIDsshow
Solenopsin A107941PROMISCUOUSPMID 12745988show
Succinonitrile, bis(amino(o-aminophenylthio)methylene)-3006531PROMISCUOUSPMID 16327214show
tetrahydrobiopterin1125PROMISCUOUS3 PMIDsshow
TETRAHYDROBIOPTERIN44257PROMISCUOUS3 PMIDsshow
Tetramethylpiperidinol N-oxyl137994PROMISCUOUSPMID 15925283show
Tilarginine4366BindingDB-show
Umbellatine2353PROMISCUOUSPMID 17418998show
Xylomethazoline5709PROMISCUOUSPMID 11028657show
Synonyms:
Inducible NO synthase
Inducible NOS
iNOS
Nitric oxide synthase, inducible
NOS type II
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
NOS2_MOUSE96.894.2
NOS2_BOVIN8880.4
NOS2_HUMAN87.980.3
NOS2_CHICK79.466
NOS3_MOUSE62.448.3
NOS3_HUMAN61.547.6
NOS3_PIG61.447.3
NOS3_BOVIN61.347.4
NOS3_RAT61.247.5
NOS1_MOUSE5541.8
NOS1_RAT54.741.9
NOS1_HUMAN54.342.2
NOS1_RABIT54.142.4
NOS2_RABIT41.841.6
CPXB_BACME36.722.2
AT1A4_HUMAN29.917.9
Q43235_VICSA28.717.6
HXK1_HUMAN28.616.1
SYI_THET828.617.3
DPYD_PIG28.517.1
NCPR_RAT28.417.7
ITAL_HUMAN28.316.3
TLR7_HUMAN28.317.4
POL_FIVPE28.215.6
TLR8_HUMAN28.115.6
Q495P6_HUMAN28.115.7
DPOD1_HUMAN28.117
Q495P7_HUMAN28.115.7
AHR_MOUSE2816.1
NCPR_RABIT2818.1
Protein-Protein Interactions:
No data available