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Target Details

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Name:BNOS
Uniprot name:NOS1_RAT
Accession Numbers:P29476 P70594
EC-Number:1.14.13.39
Organism:Rat
Rattus norvegicus
PDB IDs:1B8Q 1F20 1K2R 1K2S 1K2T 1K2U 1LZX 1LZZ 1M00 1MMV 1MMW 1OM4 1OM5 1P6H 1P6I 1P6J 1P6K 1QAU 1QAV 1QW6 1QWC 1RS6 1RS7 1TLL 1VAG 1ZVI 1ZVL 1ZZQ 1ZZR 1ZZU 2G6H 2G6I 2G6J 2G6K 2G6L 2G6M 2G6N 2HX3 2HX4 3B3M 3B3N 3B3O 3B3P 3DQR
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1-Benzyl-2-methylimidazole83699BindingDB-show
1-ethylsulfanyl-N'-phenylmethanimidamide347590DrugBank-show
1-methyl-7-nitroindazole151556BindingDB-show
1H-Indazol-7-amine88901BindingDB-show
1H-Indazol-7-ol21453601BindingDB-show
1H-Indazole-7-carbonitrile25022685BindingDB-show
1H-Indazole-7-carboxylic acid12639205BindingDB-show
2,4-Dnp-ornithine3080670BindingDB-show
2-AMINO-4,6-DIMETHYLPYRIDINE21507BindingDB-show
2-Aminoimidazole82140BindingDB-show
3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol104895PROMISCUOUSPMID 11727767show
3-BROMO-7-NITROINDAZOLE1649BindingDB-show
3-BROMO-7-NITROINDAZOLE1649DrugBank-show
3HX16058621BindingDB-show
4-bromo-1H-indazole22352548BindingDB-show
4-Chloro-1H-indazole393037BindingDB-show
4-fluoro-1H-indazole22477757BindingDB-show
4-Methoxy-1H-indazole24729333BindingDB-show
40027-64-324186467BindingDB-show
439154439154DrugBank-show
5-bromo-1H-indazole761929BindingDB-show
5-Chloro-1H-indazole69681BindingDB-show
5-Fluoro-1H-indazole17842486BindingDB-show
5-Iodo-1H-indazole21894739BindingDB-show
5-Methoxy-1H-indazole13346860BindingDB-show
5-Methyl-2-nitroaniline11356BindingDB-show
5-N-ALLYL-ARGININE5287706DrugBank-show
52885375288537DrugBank-show
52895555289555DrugBank-show
6-bromo-1H-indazole17842471BindingDB-show
6-Chloro-1H-indazole417524BindingDB-show
6-fluoro-1H-indazole17842350BindingDB-show
6-METHYL INDAZOLE12639191BindingDB-show
6-{[(3r,4r)-4-(2-{[2-(3-Fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-Yl]me46225774BindingDB-show
6-{[(3s,4s)-4-(2-{[2-(3-Fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-Yl]me42636915BindingDB-show
7-bromo-1H-indazole20323899BindingDB-show
7-chloro-1H-indazole11116249BindingDB-show
7-Iodo-1H-indazole16726525BindingDB-show
7-Nitroisoindazole1893BindingDB-show
885522-11-224728219BindingDB-show
AC1LCVP8656914BindingDB-show
Acetovanillone2214PROMISCUOUSPMID 18001708show
AE-848/30538008430989BindingDB-show
Aminopyridine10439BindingDB-show
aminopyridine-pyrrolidine, 424850913BindingDB-show
Ascensil1533BindingDB-show
Asiaticoside11954171PROMISCUOUSPMID 15643549show
benzylidenemalononitrile (BMN) deriv. 102046PROMISCUOUS2 PMIDsshow
BMY 7378 dihydrochloride2419PROMISCUOUSPMID 16043851show
Bromochlorotrifluoroethane3562PROMISCUOUSPMID 11506125show
bromophenacylbromide7454PROMISCUOUSPMID 15777770show
CHEBI:16813744291051BindingDB-show
CHEBI:25290744326640BindingDB-show
CHEBI:30831344350158BindingDB-show
CHEBI:30848844350240BindingDB-show
CHEBI:30851844350254BindingDB-show
CHEBI:30855144350271BindingDB-show
CHEBI:30855244350273BindingDB-show
CHEBI:55682344564446BindingDB-show
CHEBI:55682444564447BindingDB-show
CHEBI:64529244307159BindingDB-show
CHEBI:64539144307242BindingDB-show
CHEBI:64539744307408BindingDB-show
CHEBI:64540544307180BindingDB-show
CHEBI:64614944326868BindingDB-show
CHEBI:64615344326627BindingDB-show
CHEBI:64615544326625BindingDB-show
CHEBI:64615844326780BindingDB-show
CHEBI:64616844326816BindingDB-show
CHEBI:64619544326666BindingDB-show
CHEBI:64619744326664BindingDB-show
CHEBI:64620844326649BindingDB-show
CHEBI:64621044326718BindingDB-show
CHEBI:64937644410547BindingDB-show
CHEBI:64937744410548BindingDB-show
CHEBI:64938344410440BindingDB-show
CHEBI:64941444410603BindingDB-show
CHEBI:65121944307160BindingDB-show
CHEBI:65122744307243BindingDB-show
CHEBI:65127944307401BindingDB-show
CHEBI:65134944307178BindingDB-show
CHEBI:65136144307393BindingDB-show
CHEBI:65162444326623BindingDB-show
CHEBI:65182544326870BindingDB-show
CHEBI:65312144410552BindingDB-show
CHEBI:65313044410573BindingDB-show
CHEBI:66378245271554BindingDB-show
CHEMBL10192644331525BindingDB-show
CHEMBL10389644331546BindingDB-show
CHEMBL108685846880969BindingDB-show
CHEMBL108685946880970BindingDB-show
CHEMBL108774646880968BindingDB-show
CHEMBL109916712071049BindingDB-show
CHEMBL109916845259048BindingDB-show
CHEMBL109916910241837BindingDB-show
CHEMBL109917046237591BindingDB-show
CHEMBL109917146237587BindingDB-show
CHEMBL122260749864878BindingDB-show
CHEMBL122260846846307BindingDB-show
CHEMBL122260949864879BindingDB-show
CHEMBL122261049864880BindingDB-show
CHEMBL122267549864917BindingDB-show
CHEMBL122267649864918BindingDB-show
CHEMBL122267749864919BindingDB-show
CHEMBL122267849864920BindingDB-show
CHEMBL122274549864953BindingDB-show
CHEMBL122274646935152BindingDB-show
CHEMBL122274749864954BindingDB-show
CHEMBL123038046907789BindingDB-show
CHEMBL123038146907790BindingDB-show
CHEMBL126910350899557BindingDB-show
CHEMBL126910450899558BindingDB-show
CHEMBL126910552940828BindingDB-show
CHEMBL126910652948091BindingDB-show
CHEMBL126915652949342BindingDB-show
CHEMBL127046049831165BindingDB-show
CHEMBL127611849837180BindingDB-show
CHEMBL127611952948360BindingDB-show
CHEMBL127612052949612BindingDB-show
CHEMBL127616752942929BindingDB-show
CHEMBL127687652942270BindingDB-show
CHEMBL127696552943506BindingDB-show
CHEMBL127696652947165BindingDB-show
CHEMBL127696752948375BindingDB-show
CHEMBL127705352947134BindingDB-show
CHEMBL127705452947135BindingDB-show
CHEMBL127705552944667BindingDB-show
CHEMBL127714152946777BindingDB-show
CHEMBL127714252941903BindingDB-show
CHEMBL127714352941904BindingDB-show
CHEMBL127723252946780BindingDB-show
CHEMBL127723352940723BindingDB-show
CHEMBL127732749837182BindingDB-show
CHEMBL127741949837185BindingDB-show
CHEMBL127742049837187BindingDB-show
CHEMBL127750849837282BindingDB-show
CHEMBL127750949837284BindingDB-show
CHEMBL127760149837286BindingDB-show
CHEMBL127760249837288BindingDB-show
CHEMBL127769352941638BindingDB-show
CHEMBL127769452941918BindingDB-show
CHEMBL127778649837388BindingDB-show
CHEMBL127778749837390BindingDB-show
CHEMBL127787052948929BindingDB-show
CHEMBL127795152948411BindingDB-show
CHEMBL127795252944737BindingDB-show
CHEMBL127803752942341BindingDB-show
CHEMBL127803852948423BindingDB-show
CHEMBL127813152949000BindingDB-show
CHEMBL127813252944743BindingDB-show
CHEMBL127813352941132BindingDB-show
CHEMBL127821752941110BindingDB-show
CHEMBL16002644375462BindingDB-show
CHEMBL1612979850719BindingDB-show
CHEMBL16441244375403BindingDB-show
CHEMBL21610244417334BindingDB-show
CHEMBL21677044417331BindingDB-show
CHEMBL22639044423364BindingDB-show
CHEMBL22644544423365BindingDB-show
CHEMBL22644644423367BindingDB-show
CHEMBL22644744423368BindingDB-show
CHEMBL22644844423369BindingDB-show
CHEMBL22649944423371BindingDB-show
CHEMBL22821216220908BindingDB-show
CHEMBL23365210452321BindingDB-show
CHEMBL23365344430634BindingDB-show
CHEMBL23365444430635BindingDB-show
CHEMBL23365544430637BindingDB-show
CHEMBL23385710411355BindingDB-show
CHEMBL26204010524594BindingDB-show
CHEMBL26622611075828BindingDB-show
CHEMBL26707518785885BindingDB-show
CHEMBL2684039991876BindingDB-show
CHEMBL26852118785787BindingDB-show
CHEMBL26866844264963BindingDB-show
CHEMBL26867112283980BindingDB-show
CHEMBL2690579992513BindingDB-show
CHEMBL26916218785810BindingDB-show
CHEMBL2736599795129BindingDB-show
CHEMBL27420718785892BindingDB-show
CHEMBL27440218785857BindingDB-show
CHEMBL27440510013642BindingDB-show
CHEMBL27498444270467BindingDB-show
CHEMBL27595518785796BindingDB-show
CHEMBL29047611267277BindingDB-show
CHEMBL29087511210360BindingDB-show
CHEMBL29584810870586BindingDB-show
CHEMBL29610211056403BindingDB-show
CHEMBL29709511119989BindingDB-show
CHEMBL29720710935782BindingDB-show
CHEMBL29737210426356BindingDB-show
CHEMBL31154144322476BindingDB-show
CHEMBL31289910851593BindingDB-show
CHEMBL31322810858252BindingDB-show
CHEMBL31352610491077BindingDB-show
CHEMBL31442610613300BindingDB-show
CHEMBL31480110731514BindingDB-show
CHEMBL32982044322717BindingDB-show
CHEMBL32988310634623BindingDB-show
CHEMBL3304669993789BindingDB-show
CHEMBL34970044375357BindingDB-show
CHEMBL35183344375389BindingDB-show
CHEMBL35212244375037BindingDB-show
CHEMBL35470544375203BindingDB-show
CHEMBL37505644423374BindingDB-show
CHEMBL37589544423361BindingDB-show
CHEMBL37594344423366BindingDB-show
CHEMBL37614544423370BindingDB-show
CHEMBL38430044417315BindingDB-show
CHEMBL38481544417316BindingDB-show
CHEMBL3876211486109BindingDB-show
CHEMBL387649793910BindingDB-show
CHEMBL388459905692BindingDB-show
CHEMBL3918611268382BindingDB-show
CHEMBL403919843967BindingDB-show
CHEMBL41279710068818BindingDB-show
CHEMBL41290118785794BindingDB-show
CHEMBL4134311348978BindingDB-show
CHEMBL4146089873870BindingDB-show
CHEMBL4155111473924BindingDB-show
CHEMBL41607111428573BindingDB-show
CHEMBL41669618785938BindingDB-show
CHEMBL41974018356525BindingDB-show
CHEMBL4209310935781BindingDB-show
CHEMBL42117510335415BindingDB-show
CHEMBL42728616058622BindingDB-show
CHEMBL4286311256080BindingDB-show
CHEMBL4296811175135BindingDB-show
CHEMBL429699797393BindingDB-show
CHEMBL4324011438569BindingDB-show
CHEMBL432459796600BindingDB-show
CHEMBL43326011722865BindingDB-show
CHEMBL436789839201BindingDB-show
CHEMBL4381510358114BindingDB-show
CHEMBL4393710447220BindingDB-show
CHEMBL4399711066357BindingDB-show
CHEMBL44027018785936BindingDB-show
CHEMBL44299911023747BindingDB-show
CHEMBL44697144592992BindingDB-show
CHEMBL4496410957845BindingDB-show
CHEMBL4502111088167BindingDB-show
CHEMBL45023444592965BindingDB-show
CHEMBL45058325231660BindingDB-show
CHEMBL4511311131126BindingDB-show
CHEMBL4511910990090BindingDB-show
CHEMBL4513210903407BindingDB-show
CHEMBL45154144585510BindingDB-show
CHEMBL4524310086655BindingDB-show
CHEMBL45295644585508BindingDB-show
CHEMBL4544111758669BindingDB-show
CHEMBL45657916726526BindingDB-show
CHEMBL4691311034234BindingDB-show
CHEMBL46936644592417BindingDB-show
CHEMBL4697411011882BindingDB-show
CHEMBL47019344592351BindingDB-show
CHEMBL47926844570753BindingDB-show
CHEMBL47926944570757BindingDB-show
CHEMBL47927044570758BindingDB-show
CHEMBL47928044570846BindingDB-show
CHEMBL47946944570847BindingDB-show
CHEMBL47966644570880BindingDB-show
CHEMBL47966744570881BindingDB-show
CHEMBL48024744570692BindingDB-show
CHEMBL48025444570843BindingDB-show
CHEMBL48025544570844BindingDB-show
CHEMBL48025644570845BindingDB-show
CHEMBL48041844570883BindingDB-show
CHEMBL4807011823487BindingDB-show
CHEMBL48084044570837BindingDB-show
CHEMBL48103244570839BindingDB-show
CHEMBL48103324202627BindingDB-show
CHEMBL48141344570727BindingDB-show
CHEMBL48142044570690BindingDB-show
CHEMBL48146544570759BindingDB-show
CHEMBL48181544570760BindingDB-show
CHEMBL48181625210263BindingDB-show
CHEMBL48200344570684BindingDB-show
CHEMBL48220544570686BindingDB-show
CHEMBL48394044592963BindingDB-show
CHEMBL48397344592964BindingDB-show
CHEMBL48429744586039BindingDB-show
CHEMBL48482544592993BindingDB-show
CHEMBL48482644592994BindingDB-show
CHEMBL48516044592966BindingDB-show
CHEMBL49958344586041BindingDB-show
CHEMBL50488312194801BindingDB-show
CHEMBL50801444570842BindingDB-show
CHEMBL51069244585511BindingDB-show
CHEMBL51213644592415BindingDB-show
CHEMBL51370244592416BindingDB-show
CHEMBL51674044585509BindingDB-show
CHEMBL51674144585512BindingDB-show
CHEMBL51676424990311BindingDB-show
CHEMBL51722144570755BindingDB-show
CHEMBL51799544570882BindingDB-show
CHEMBL51977244570841BindingDB-show
CHEMBL51978944570683BindingDB-show
CHEMBL52009944570691BindingDB-show
CHEMBL52064544592991BindingDB-show
CHEMBL52077225210265BindingDB-show
CHEMBL52125444570688BindingDB-show
CHEMBL55288244178937BindingDB-show
CHEMBL630544264138BindingDB-show
CHEMBL638844264199BindingDB-show
CHEMBL639810013856BindingDB-show
CHEMBL640144264200BindingDB-show
CHEMBL657344264451BindingDB-show
CHEMBL6668222646274BindingDB-show
CHEMBL787318785914BindingDB-show
CHEMBL78919793824BindingDB-show
CHEMBL793110977064BindingDB-show
CHEMBL794510445220BindingDB-show
CHEMBL794618785788BindingDB-show
CHEMBL796918785905BindingDB-show
CHEMBL804118785824BindingDB-show
CHEMBL806518785786BindingDB-show
CHEMBL808818785851BindingDB-show
CHEMBL810518785805BindingDB-show
CHEMBL810618785840BindingDB-show
CHEMBL827218785825BindingDB-show
CHEMBL828118785933BindingDB-show
CHEMBL828818785778BindingDB-show
CHEMBL829218785878BindingDB-show
CHEMBL830218785910BindingDB-show
CHEMBL830418785802BindingDB-show
CHEMBL83659990159BindingDB-show
CHEMBL839011744927BindingDB-show
CHEMBL8681018414528BindingDB-show
CHEMBL8718611417668BindingDB-show
CHEMBL8718744320347BindingDB-show
CHEMBL8752915512769BindingDB-show
CHEMBL8754415512781BindingDB-show
CHEMBL8810744323742BindingDB-show
CHEMBL8816510825716BindingDB-show
CHEMBL8816610378286BindingDB-show
CHEMBL881779860615BindingDB-show
CHEMBL8817844322522BindingDB-show
CHEMBL8826710084004BindingDB-show
CHEMBL8830910751514BindingDB-show
CHEMBL8866510825774BindingDB-show
CHEMBL8869610682300BindingDB-show
CHEMBL8937044322538BindingDB-show
CHEMBL8945410489277BindingDB-show
CHEMBL8969644322532BindingDB-show
CHEMBL9096310610048BindingDB-show
CHEMBL912569994346BindingDB-show
CHEMBL9173444322552BindingDB-show
CHEMBL9220811065659BindingDB-show
CHEMBL9249310084782BindingDB-show
CHEMBL966809842658BindingDB-show
CID 984284210499987BindingDB-show
CID 99272379927237BindingDB-show
Dextrone15939PROMISCUOUSPMID 18985485show
Diethylnitrosoamine5921PROMISCUOUSPMID 17418998show
Diferaloylmethane969516PROMISCUOUSPMID 14634121show
Dimethyl methoxycarbonylpropenyl phosphate5355863PROMISCUOUSPMID 17438462show
dipeptide amide inhibitor I656910BindingDB-show
dipeptide amide inhibitor I656910DrugBank-show
Efetozole208911BindingDB-show
Essigsaeure176DrugBank-show
Eusynstyelamide A44178935BindingDB-show
Eusynstyelamide B44178936BindingDB-show
Fasudil hydrochloride3547PROMISCUOUSPMID 17111028show
Fasudil hydrochloride163751PROMISCUOUSPMID 17111028show
Genisterin5280961PROMISCUOUSPMID 17881116show
Hydrazinecarboximidamide2146BindingDB-show
Hydroxyethylene derivative, 1024776426BindingDB-show
Hydroxyethylene derivative, 1124776427BindingDB-show
Hydroxyethylene derivative, 424776421BindingDB-show
Hydroxyethylene derivative, 524776422BindingDB-show
Hydroxyethylene derivative, 624776423BindingDB-show
Hydroxyethylene derivative, 724776424BindingDB-show
Hydroxyethylene derivative, 824776425BindingDB-show
Hydroxyethylene derivative, 923624983BindingDB-show
Isoflurane3763PROMISCUOUSPMID 12105371show
ISOFLURANE4369440PROMISCUOUSPMID 12105371show
J1445259041BindingDB-show
JI224850786BindingDB-show
JI324798097BindingDB-show
JI424798098BindingDB-show
JI725021186BindingDB-show
Kinome_133344586040BindingDB-show
L-NAME39836BindingDB-show
L-nitroarginine440005BindingDB-show
L-nitroarginine440005DrugBank-show
L-THIOCITRULLINE2733514BindingDB-show
Lificiguat5712PROMISCUOUSPMID 17401444show
Mannose185698DrugBank-show
N omega-Nitro-L-Arginine-Containing Dipeptide, 1656911BindingDB-show
N omega-Nitro-L-Arginine-Containing Dipeptide, 1656911DrugBank-show
N omega-Nitro-L-Arginine-Containing Dipeptide, 2656912BindingDB-show
N omega-Nitro-L-Arginine-Containing Dipeptide, 2656912DrugBank-show
N(omega)-hydroxyarginine123895DrugBank-show
N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE1433BindingDB-show
N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE1433DrugBank-show
N-(4-(2-((3-CHLOROPHENYLMETHYL)AMINO)ETHYL)PHENYL)-2-THIOPHECARBOXAMIDINE449021DrugBank-show
N-BUTYL-N'-HYDROXYGUANIDINE447030DrugBank-show
N-ISOPROPYL-N'-HYDROXYGUANIDINE447029DrugBank-show
N-OMEGA-PROPYL-L-ARGININE5287494DrugBank-show
NCGC00015566-012733506BindingDB-show
Oximetazolinum4636PROMISCUOUSPMID 11028657show
Pyrrolidinedithiocarbamate65351PROMISCUOUS3 PMIDsshow
Riboflavin710DrugBank-show
Rosigilitazone77999PROMISCUOUSPMID 14709329show
S-Ethyl tfmp-isothiourea3311DrugBank-show
S-Methylisothiopseudouronium5142PROMISCUOUS5 PMIDsshow
S-Methylthiocitrulline107968BindingDB-show
Semaxinib5329098PROMISCUOUSPMID 15064225show
SIMVASTATIN54454PROMISCUOUS2 PMIDsshow
Solenopsin A107941PROMISCUOUSPMID 12745988show
Succinonitrile, bis(amino(o-aminophenylthio)methylene)-3006531PROMISCUOUSPMID 16327214show
Targinine132862BindingDB-show
TETRAHYDROBIOPTERIN44257DrugBank-show
tetrahydrobiopterin1125DrugBank-show
tetrahydrobiopterin1125PROMISCUOUS3 PMIDsshow
TETRAHYDROBIOPTERIN44257PROMISCUOUS3 PMIDsshow
Tetramethylpiperidinol N-oxyl137994PROMISCUOUSPMID 15925283show
Trim1359BindingDB-show
Triphosphopyridine nucleotide5886DrugBank-show
Triphosphopyridine nucleotide5885DrugBank-show
Umbellatine2353PROMISCUOUSPMID 17418998show
Xylomethazoline5709PROMISCUOUSPMID 11028657show
ZINC2689453210441839BindingDB-show
Synonyms:
BNOS
Constitutive NOS
N-NOS
NC-NOS
Neuronal NOS
Nitric oxide synthase, brain
nNOS
NOS type I
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
NOS1_MOUSE98.397.8
NOS1_HUMAN96.393.6
NOS1_RABIT95.392.3
NOS3_BOVIN60.748.2
NOS3_HUMAN6048
NOS3_PIG59.947.2
NOS3_MOUSE59.547.4
NOS3_RAT59.447.4
NOS2_CHICK55.943.4
NOS2_HUMAN55.643.5
NOS2_BOVIN55.542.8
NOS2_MOUSE54.741.8
NOS2_RAT54.741.9
CPXB_BACME31.418.6
METH_ECOLI30.118.3
MRP1_HUMAN29.117
POL_SIVM12916.2
Q9F0I5_PAEMA28.916.9
MRP5_HUMAN28.717.8
POL_HV1B128.416.5
POL_HV1Y228.416.4
ADCY5_RABIT28.316.6
KIF11_HUMAN28.216.1
POL_HV2RO28.116.3
POL_HV1A228.116
DPOLA_HUMAN27.815.6
POL_HV1H227.415.9
ITA11_HUMAN27.315.7
KCNH7_HUMAN27.215.5
POL_HV1N527.115.6
Protein-Protein Interactions:
No data available