Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Target Details

add
Name:Dual specificity mitogen-activated protein kinase kinase 4
Uniprot name:MP2K4_HUMAN
Accession Numbers:P45985 Q5U0B8
EC-Number:2.7.12.2
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
ACHP10451420BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:30525144348997BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL12589810231458BindingDB-show
CHEMBL17305010295268BindingDB-show
CHEMBL1734849912932BindingDB-show
CHEMBL21580316046126BindingDB-show
CHEMBL36007710266458BindingDB-show
CHEMBL50724944591740BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
JNK Inhibitor V11422035BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MEK Inhibitor I9951490BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
Phenylaethylsenfoel16741PROMISCUOUSPMID 14729592show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
c-Jun N-terminal kinase kinase 1
Dual specificity mitogen-activated protein kinase kinase 4
JNK-activating kinase 1
JNKK
MAP kinase kinase 4
SAPK/ERK kinase 1
SEK1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
MP2K3_MOUSE61.844.1
MP2K6_MOUSE59.645.6
MP2K7_HUMAN52.239.1
MP2K2_HUMAN44.931.1
MP2K2_MOUSE44.829.4
MP2K2_RAT44.530.2
MP2K1_RAT42.929.1
MP2K1_MOUSE42.929.1
MP2K1_HUMAN42.929.3
STK6_HUMAN39.122.2
KAPA_YEAST36.420.5
CDK6_HUMAN34.920.4
A4D1G0_HUMAN34.920.4
PIM1_HUMAN34.822.2
KAPCA_RAT34.719
MK03_RAT34.520.9
MK03_MOUSE34.320.9
GSK3A_HUMAN34.220.3
KAPCB_RAT34.119.3
MK03_HUMAN34.120.6
KAPCB_MOUSE34.119.3
KAPCB_HUMAN32.818.7
NIFH1_AZOVI32.618.4
ANM3_RAT32.516.6
ODBB_HUMAN32.316.9
GSHR_PLAFK32.318.3
PIM1_FELCA32.320.5
ODBB_RAT32.117.3
KAPCG_HUMAN32.118.6
CSK_HUMAN32.120
Protein-Protein Interactions: