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Target Details

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Name:Matrix metalloproteinase-3
Uniprot name:MMP3_HUMAN
Accession Numbers:B2R8B8 P08254 Q3B7S0 Q6GRF8
EC-Number:3.4.24.17
Organism:Homo sapiens
Human
PDB IDs:1B3D 1B8Y 1BIW 1BM6 1BQO 1C3I 1C8T 1CAQ 1CIZ 1CQR 1D5J 1D7X 1D8F 1D8M 1G05 1G49 1G4K 1HFS 1HY7 1M1W 1OO9 1QIA 1QIC 1SLM 1SLN 1UEA 1UMS 1UMT 1USN 2D1O 2JNP 2JT5 2JT6 2SRT 2USN 3USN
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
(1N)-4-N-BUTOXYPHENYLSULFONYL-(2R)-N-HYDROXYCARBOXAMIDO-(4S)-METHANESULFONYLAMINO-PYRROLIDINE5287415DrugBank-show
1-BENZYL-3-(4-METHOXY-BENZENESULFONYL)-6-OXO-HEXAHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE445018DrugBank-show
3-(1H-INDOL-3-YL)-2-[4-(4-PHENYL-PIPERIDIN-1-YL)-BENZENESULFONYLAMINO]-PROPIONIC ACID5288108DrugBank-show
4-methoxybenzenesulfinate3952261DrugBank-show
4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL]-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE3342298BindingDB-show
5-methyl-5-(4-phenoxyphenyl)barbituric acid1836DrugBank-show
A DISUBSTITUTED SUCCINYL CAPROLACTAM HYDROXYMATE MMP3 INHIBITOR5289325DrugBank-show
alpha-arylsulfonylamino carboxylate 2S9887870BindingDB-show
alpha-sulfone 219822926BindingDB-show
alpha-sulfone 27b11697283BindingDB-show
alpha-sulfone 27d11532911BindingDB-show
alpha-sulfone 27e11719408BindingDB-show
alpha-sulfone 27g11561491BindingDB-show
alpha-sulfone 35a11633617BindingDB-show
alpha-sulfone 35c11533203BindingDB-show
alpha-sulfone 35d11561839BindingDB-show
alpha-sulfone 35f9890734BindingDB-show
alpha-sulfone 35g11705503BindingDB-show
alpha-sulfone 35h11684850BindingDB-show
beta-Methylpyridine7970DrugBank-show
beta-sulfone 7b9867183BindingDB-show
beta-sulfone 7c11613649BindingDB-show
beta-sulfone 7d11548264BindingDB-show
beta-sulfone 7e11641261BindingDB-show
beta-sulfone 7f11526076BindingDB-show
CGS 27023A446504BindingDB-show
CGS 27023A Analog 410853176BindingDB-show
CGS 27023A Analog 510613211BindingDB-show
CGS 27023A Analog 610732988BindingDB-show
CGS 27023A Analog 711779797BindingDB-show
CGS 27023A Analog 7111794888BindingDB-show
CGS 27023A Analog 810640100BindingDB-show
CGS 27023A Analog 910709434BindingDB-show
CHEMBL107720346844314BindingDB-show
CHEMBL107839611716217BindingDB-show
CHEMBL108231746871741BindingDB-show
CHEMBL108231822485381BindingDB-show
CHEMBL10823819802768BindingDB-show
CHEMBL108423846871738BindingDB-show
CHEMBL108450946871739BindingDB-show
CHEMBL108451046871740BindingDB-show
CHEMBL108525720735209BindingDB-show
CHEMBL128785117754305BindingDB-show
CHEMBL16378511145072BindingDB-show
CHEMBL16385211123768BindingDB-show
CHEMBL16389711782945BindingDB-show
CHEMBL16389811762364BindingDB-show
CHEMBL16396411143491BindingDB-show
CHEMBL16401011111170BindingDB-show
CHEMBL16419244378570BindingDB-show
CHEMBL16423010991272BindingDB-show
CHEMBL16433510973334BindingDB-show
CHEMBL16438411111661BindingDB-show
CHEMBL16450111112186BindingDB-show
CHEMBL16450211004130BindingDB-show
CHEMBL16454810916230BindingDB-show
CHEMBL16454910320779BindingDB-show
CHEMBL16458310862121BindingDB-show
CHEMBL16460110915832BindingDB-show
CHEMBL16463911037549BindingDB-show
CHEMBL16498011070343BindingDB-show
CHEMBL16499911825340BindingDB-show
CHEMBL16514411762457BindingDB-show
CHEMBL16525911123530BindingDB-show
CHEMBL16532110863084BindingDB-show
CHEMBL16674510959278BindingDB-show
CHEMBL16680810961187BindingDB-show
CHEMBL16684611100100BindingDB-show
CHEMBL16697911036655BindingDB-show
CHEMBL16732011143174BindingDB-show
CHEMBL16742110874736BindingDB-show
CHEMBL16742211015350BindingDB-show
CHEMBL16745311091752BindingDB-show
CHEMBL16746010895953BindingDB-show
CHEMBL16756610915473BindingDB-show
CHEMBL16784610903927BindingDB-show
CHEMBL16819311004467BindingDB-show
CHEMBL27612410993810BindingDB-show
CHEMBL2999369821077BindingDB-show
CHEMBL31034710808023BindingDB-show
CHEMBL31133610834357BindingDB-show
CHEMBL31215210739270BindingDB-show
CHEMBL3122189843079BindingDB-show
CHEMBL31295210765385BindingDB-show
CHEMBL31340611800904BindingDB-show
CHEMBL31383610645086BindingDB-show
CHEMBL31405910670761BindingDB-show
CHEMBL31406410594938BindingDB-show
CHEMBL31420410642533BindingDB-show
CHEMBL31436910836183BindingDB-show
CHEMBL31459610545870BindingDB-show
CHEMBL31491810618255BindingDB-show
CHEMBL31504311797374BindingDB-show
CHEMBL31555810760373BindingDB-show
CHEMBL31590510569469BindingDB-show
CHEMBL31594910831751BindingDB-show
CHEMBL34905911145044BindingDB-show
CHEMBL34906310958991BindingDB-show
CHEMBL34929311002384BindingDB-show
CHEMBL35011010972232BindingDB-show
CHEMBL35012611079846BindingDB-show
CHEMBL35028410895886BindingDB-show
CHEMBL35100610895215BindingDB-show
CHEMBL35147110972180BindingDB-show
CHEMBL35161911024522BindingDB-show
CHEMBL35229210925792BindingDB-show
CHEMBL35250511048363BindingDB-show
CHEMBL35312311812106BindingDB-show
CHEMBL35343310885510BindingDB-show
CHEMBL35374910958992BindingDB-show
CHEMBL41949110526209BindingDB-show
CHEMBL42078410807240BindingDB-show
CHEMBL43238510527557BindingDB-show
CHEMBL43257210742152BindingDB-show
CHEMBL43276010552056BindingDB-show
CHEMBL43326210550399BindingDB-show
CHEMBL43643110915735BindingDB-show
CHEMBL4364410741133BindingDB-show
CHEMBL46605944123600BindingDB-show
CHEMBL5632110336856BindingDB-show
CHEMBL5746110835069BindingDB-show
CHEMBL8204710738924BindingDB-show
CHEMBL8221210645799BindingDB-show
CHEMBL8223210667012BindingDB-show
CHEMBL8233110570770BindingDB-show
CHEMBL8275910527787BindingDB-show
CHEMBL8278310691191BindingDB-show
CHEMBL8282710502537BindingDB-show
CHEMBL8285510789971BindingDB-show
CHEMBL8286910833242BindingDB-show
CHEMBL8309110833044BindingDB-show
CHEMBL8368510787514BindingDB-show
CHEMBL8386410784639BindingDB-show
CHEMBL8415310693625BindingDB-show
CHEMBL8423510714796BindingDB-show
CHEMBL8425510593373BindingDB-show
CHEMBL8440810621353BindingDB-show
CHEMBL8459410686890BindingDB-show
CHEMBL8459810738429BindingDB-show
CHEMBL8481410785400BindingDB-show
CHEMBL8491811797375BindingDB-show
CHEMBL850309821883BindingDB-show
CHEMBL8510810738103BindingDB-show
CHEMBL8531910599498BindingDB-show
CHEMBL8542710734191BindingDB-show
CHEMBL8562010692726BindingDB-show
CHEMBL8586922907131BindingDB-show
CHEMBL8611310524926BindingDB-show
CHEMBL8618910640178BindingDB-show
Cipemastat9824350BindingDB-show
FIN6852147BindingDB-show
Hydroxamate 1210594000BindingDB-show
Hydroxamate 1815296597BindingDB-show
Hydroxamate 910445302BindingDB-show
hydroxamate analogue 226539670BindingDB-show
HYDROXYAMINOVALINE444599DrugBank-show
Marimastat119031DrugBank-show
mmp-8 inhibitor i10761128BindingDB-show
N-HYDROXY 1N(4-METHOXYPHENYL)SULFONYL-4-(Z,E-N-METHOXYIMINO)PYRROLIDINE-2R-CARBOXAMIDE445010DrugBank-show
N-HYDROXY-1-(4-METHOXYPHENYL)SULFONYL-4-BENZYLOXYCARBONYL-PIPERAZINE-2-CARBOXAMIDE5289389DrugBank-show
N-HYDROXY-4-[(4-METHOXYLPHENYL)SULFONYL]-2,2-DIMETHYL-HEXAHYDRO-1,4-THIAZEPINE-3(S)-CARBOXAMIDE5288814DrugBank-show
NGH448002BindingDB-show
PD-16946910549609BindingDB-show
R-2-{[4'-METHOXY-(1,1'-BIPHENYL)-4-YL]-SULFONYL}-AMINO-6-METHOXY-HEX-4-YNOIC ACID446165DrugBank-show
Rofecoxib5090PROMISCUOUSPMID 16580899show
Semaxinib5329098PROMISCUOUSPMID 12777073show
SIMVASTATIN54454DrugBank-show
Trihydroxypropane753SuperTarget-show
Synonyms:
Matrix metalloproteinase-3
MMP-3
SL-1
Stromelysin-1
Transin-1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
MMP3_RABIT9184.1
MMP3_CANFA88.780.8
MMP10_HUMAN88.178.2
MMP3_MOUSE8777.1
MMP1_RABIT7151.7
MMP1_HUMAN70.753
MMP12_HUMAN68.751.4
MMP8_HUMAN68.149.9
MMP13_HUMAN65.149
MMP13_MOUSE64.849.4
MMP13_RAT64.149
MMP12_MOUSE61.847.6
MMP11_MOUSE45.734.4
MMP14_HUMAN45.233.2
MMP2_RAT44.332.6
MMP2_MOUSE44.232.8
MMP16_HUMAN44.132.3
MMP2_HUMAN4432.4
MMP28_HUMAN41.630
MMP9_CANFA38.429.1
MMP9_HUMAN37.427.6
MMP9_MOUSE36.727.5
MMP9_RAT36.727.2
MMP7_HUMAN35.527.7
CP7A1_HUMAN32.319.6
GANA_BACLD31.718.6
Q9KWT6_SPHSX31.317.2
GLUCB_CAEEL31.118.3
CATA_HUMAN31.119.5
FENR_ANASO3117.4
Protein-Protein Interactions: