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Target Details

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Name:Macrophage metalloelastase
Uniprot name:MMP12_HUMAN
Accession Numbers:B2R9X8 B7ZLF6 P39900 Q2M1L9
EC-Number:3.4.24.65
Organism:Homo sapiens
Human
PDB IDs:1JIZ 1JK3 1OS2 1OS9 1RMZ 1ROS 1UTT 1UTZ 1Y93 1YCM 1Z3J 2HU6 2JXY 2K2G 2K9C 2OXU 2OXW 2OXZ 2POJ 2W0D 2WO8 2WO9 2WOA 2Z2D 3BA0 3EHX 3EHY 3F15 3F16 3F17 3F18 3F19 3F1A
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
2-[2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)ETHYL]-4-(4'-ETHOXY-1,1'-BIPHENYL-4-YL)-4-OXOBUTANOIC ACID448384DrugBank-show
2ow99896504BindingDB-show
3-(benzenesulfonyl)-N-hydroxy-heptanamide9838786BindingDB-show
3-PHENYL-3-({[4-(4-PYRIDIN-4-YLPHENYL)THIEN-2-YL]CARBONYL}AMINO)PROPANOIC ACID448942BindingDB-show
3-PHENYL-3-({[4-(4-PYRIDIN-4-YLPHENYL)THIEN-2-YL]CARBONYL}AMINO)PROPANOIC ACID448942DrugBank-show
5-METHOXYBENZIMIDAZOLE78598BindingDB-show
6-Methyl-2H-1,4-benzoxazin-3(4H)-one2763839BindingDB-show
Acethydroxamsaeure1990DrugBank-show
Acethydroxamsaeure1990SuperTarget-show
AGELADINE A10089677BindingDB-show
BATIMASTAT5362422DrugBank-show
CHEBI:65405744580108BindingDB-show
CHEMBL10849410183064BindingDB-show
CHEMBL10921410136680BindingDB-show
CHEMBL10935310296785BindingDB-show
CHEMBL10957910136924BindingDB-show
CHEMBL10960311016072BindingDB-show
CHEMBL10965511101785BindingDB-show
CHEMBL10977010116107BindingDB-show
CHEMBL10980611730086BindingDB-show
CHEMBL10986110138303BindingDB-show
CHEMBL11075010206106BindingDB-show
CHEMBL11097010162900BindingDB-show
CHEMBL11117910204303BindingDB-show
CHEMBL11125710274748BindingDB-show
CHEMBL1114509932290BindingDB-show
CHEMBL11167810114318BindingDB-show
CHEMBL1118569866250BindingDB-show
CHEMBL11487811967143BindingDB-show
CHEMBL11526310439082BindingDB-show
CHEMBL1169449885136BindingDB-show
CHEMBL1184979955795BindingDB-show
CHEMBL14628944364224BindingDB-show
CHEMBL14671844364037BindingDB-show
CHEMBL14748944364119BindingDB-show
CHEMBL14760444364251BindingDB-show
CHEMBL14788144364121BindingDB-show
CHEMBL14788244364122BindingDB-show
CHEMBL14817144364250BindingDB-show
CHEMBL14821444364249BindingDB-show
CHEMBL14840644364111BindingDB-show
CHEMBL17865211327633BindingDB-show
CHEMBL17917744389253BindingDB-show
CHEMBL17928544389285BindingDB-show
CHEMBL17928711475677BindingDB-show
CHEMBL17928811292680BindingDB-show
CHEMBL18076244389231BindingDB-show
CHEMBL18087510408590BindingDB-show
CHEMBL1817079993891BindingDB-show
CHEMBL18181744389199BindingDB-show
CHEMBL18187844389246BindingDB-show
CHEMBL18203810318433BindingDB-show
CHEMBL18341044391352BindingDB-show
CHEMBL18707944394681BindingDB-show
CHEMBL19931411529867BindingDB-show
CHEMBL19966611639846BindingDB-show
CHEMBL20120611675055BindingDB-show
CHEMBL20129811581319BindingDB-show
CHEMBL20287511609208BindingDB-show
CHEMBL20313911588332BindingDB-show
CHEMBL20319911543178BindingDB-show
CHEMBL22826744426845BindingDB-show
CHEMBL22826844426847BindingDB-show
CHEMBL22831844426849BindingDB-show
CHEMBL22831911397130BindingDB-show
CHEMBL22832011202395BindingDB-show
CHEMBL22907010223757BindingDB-show
CHEMBL22907210344465BindingDB-show
CHEMBL23008444426076BindingDB-show
CHEMBL23008544426077BindingDB-show
CHEMBL23019444426073BindingDB-show
CHEMBL23019644426074BindingDB-show
CHEMBL23101244426071BindingDB-show
CHEMBL24046410195307BindingDB-show
CHEMBL24046544439853BindingDB-show
CHEMBL24064810312268BindingDB-show
CHEMBL24065210175426BindingDB-show
CHEMBL24065310195527BindingDB-show
CHEMBL24065410311501BindingDB-show
CHEMBL24085210218128BindingDB-show
CHEMBL24085410290029BindingDB-show
CHEMBL24085510312372BindingDB-show
CHEMBL24104810195069BindingDB-show
CHEMBL24105110175077BindingDB-show
CHEMBL24714010051236BindingDB-show
CHEMBL24714144441019BindingDB-show
CHEMBL24734644441021BindingDB-show
CHEMBL24734744441023BindingDB-show
CHEMBL24734844441024BindingDB-show
CHEMBL24754544441025BindingDB-show
CHEMBL24754644441027BindingDB-show
CHEMBL24774244441028BindingDB-show
CHEMBL24774344441029BindingDB-show
CHEMBL24794644441031BindingDB-show
CHEMBL24794744441032BindingDB-show
CHEMBL24796610239803BindingDB-show
CHEMBL24814844441033BindingDB-show
CHEMBL24817210127901BindingDB-show
CHEMBL24817310311498BindingDB-show
CHEMBL2483239979489BindingDB-show
CHEMBL24852344441018BindingDB-show
CHEMBL24852410366352BindingDB-show
CHEMBL24924944445277BindingDB-show
CHEMBL24985944445270BindingDB-show
CHEMBL24986044445271BindingDB-show
CHEMBL24986144445272BindingDB-show
CHEMBL24986244445274BindingDB-show
CHEMBL24986344445276BindingDB-show
CHEMBL25005744445255BindingDB-show
CHEMBL25005844445256BindingDB-show
CHEMBL25005944445258BindingDB-show
CHEMBL25006944445267BindingDB-show
CHEMBL25007044445268BindingDB-show
CHEMBL25108144445261BindingDB-show
CHEMBL25142344445263BindingDB-show
CHEMBL25142444445264BindingDB-show
CHEMBL25142544445265BindingDB-show
CHEMBL25142644445266BindingDB-show
CHEMBL25146544445279BindingDB-show
CHEMBL25193744445200BindingDB-show
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CHEMBL25232744445242BindingDB-show
CHEMBL25252244445245BindingDB-show
CHEMBL25252344445246BindingDB-show
CHEMBL25289310252411BindingDB-show
CHEMBL25296544445209BindingDB-show
CHEMBL25317244445210BindingDB-show
CHEMBL25318844445230BindingDB-show
CHEMBL25318944445231BindingDB-show
CHEMBL25337244445212BindingDB-show
CHEMBL25337344445213BindingDB-show
CHEMBL25337444445215BindingDB-show
CHEMBL25337544445216BindingDB-show
CHEMBL25360544445219BindingDB-show
CHEMBL25380144445206BindingDB-show
CHEMBL25382044445221BindingDB-show
CHEMBL25382324755074BindingDB-show
CHEMBL25383544445233BindingDB-show
CHEMBL25400644445207BindingDB-show
CHEMBL25403844445234BindingDB-show
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CHEMBL25423844445223BindingDB-show
CHEMBL25423944445224BindingDB-show
CHEMBL25424044445225BindingDB-show
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CHEMBL25440444445248BindingDB-show
CHEMBL25440544445249BindingDB-show
CHEMBL25440644445251BindingDB-show
CHEMBL25444844445226BindingDB-show
CHEMBL25461044445253BindingDB-show
CHEMBL25461144445254BindingDB-show
CHEMBL25462744445201BindingDB-show
CHEMBL25465744445228BindingDB-show
CHEMBL25482144445239BindingDB-show
CHEMBL25483744445202BindingDB-show
CHEMBL25483844445203BindingDB-show
CHEMBL25505144445205BindingDB-show
CHEMBL27008344457233BindingDB-show
CHEMBL29037710030422BindingDB-show
CHEMBL29864710467565BindingDB-show
CHEMBL29994610732349BindingDB-show
CHEMBL3082779851911BindingDB-show
CHEMBL32121310138589BindingDB-show
CHEMBL32279510136925BindingDB-show
CHEMBL32516310395015BindingDB-show
CHEMBL35612444364280BindingDB-show
CHEMBL35853910367355BindingDB-show
CHEMBL36050944394814BindingDB-show
CHEMBL36209944394703BindingDB-show
CHEMBL36421244394645BindingDB-show
CHEMBL36477544394886BindingDB-show
CHEMBL3661119982414BindingDB-show
CHEMBL36714844389227BindingDB-show
CHEMBL36801310091931BindingDB-show
CHEMBL37327544406790BindingDB-show
CHEMBL37770011717997BindingDB-show
CHEMBL37924711581283BindingDB-show
CHEMBL38812410139040BindingDB-show
CHEMBL38969144426848BindingDB-show
CHEMBL39128810175219BindingDB-show
CHEMBL39137610289842BindingDB-show
CHEMBL39138810319098BindingDB-show
CHEMBL39223144441026BindingDB-show
CHEMBL39223244441030BindingDB-show
CHEMBL39283710321975BindingDB-show
CHEMBL39286710311947BindingDB-show
CHEMBL39344310031295BindingDB-show
CHEMBL39394410239762BindingDB-show
CHEMBL39408444441020BindingDB-show
CHEMBL39429444441022BindingDB-show
CHEMBL39436244426075BindingDB-show
CHEMBL39436344426078BindingDB-show
CHEMBL39571223661684BindingDB-show
CHEMBL39579944426072BindingDB-show
CHEMBL39587710175323BindingDB-show
CHEMBL39587810129190BindingDB-show
CHEMBL39588010175331BindingDB-show
CHEMBL39845044445220BindingDB-show
CHEMBL39866244445250BindingDB-show
CHEMBL39883844445237BindingDB-show
CHEMBL39889244445214BindingDB-show
CHEMBL39907044445204BindingDB-show
CHEMBL39930444445217BindingDB-show
CHEMBL39950444445229BindingDB-show
CHEMBL39968444445218BindingDB-show
CHEMBL39968544445222BindingDB-show
CHEMBL39990844445252BindingDB-show
CHEMBL39999744445262BindingDB-show
CHEMBL39999828602444BindingDB-show
CHEMBL39999944445269BindingDB-show
CHEMBL40035744445278BindingDB-show
CHEMBL40035844445280BindingDB-show
CHEMBL40044944445257BindingDB-show
CHEMBL40085044445273BindingDB-show
CHEMBL40085144445275BindingDB-show
CHEMBL40272044445244BindingDB-show
CHEMBL40420544445241BindingDB-show
CHEMBL41975010296475BindingDB-show
CHEMBL42225010224396BindingDB-show
CHEMBL42225111016073BindingDB-show
CHEMBL42413044364266BindingDB-show
CHEMBL42786110174981BindingDB-show
CHEMBL42821210239526BindingDB-show
CHEMBL42876244445281BindingDB-show
CHEMBL42911210218353BindingDB-show
CHEMBL43168010009978BindingDB-show
CHEMBL43812510175070BindingDB-show
CHEMBL43851944445211BindingDB-show
CHEMBL44004810196192BindingDB-show
CHEMBL44228644445243BindingDB-show
CHEMBL44593944445199BindingDB-show
CHEMBL44922825263244BindingDB-show
CHEMBL47384124958549BindingDB-show
CHEMBL49395825263241BindingDB-show
CHEMBL49694210224181BindingDB-show
CHEMBL49798544580539BindingDB-show
CHEMBL50742044580458BindingDB-show
CHEMBL51543925263245BindingDB-show
CHEMBL52303425066764BindingDB-show
CHEMBL52303525263236BindingDB-show
CHEMBL54975625065108BindingDB-show
CHEMBL54997025066154BindingDB-show
CHEMBL55003844224245BindingDB-show
CHEMBL55056244248815BindingDB-show
CHEMBL55070244248697BindingDB-show
CHEMBL55078625064704BindingDB-show
CHEMBL55090725064906BindingDB-show
CHEMBL55098444248450BindingDB-show
CHEMBL55111025064489BindingDB-show
CHEMBL55118725064283BindingDB-show
CHEMBL55119045269911BindingDB-show
CHEMBL55165525064053BindingDB-show
CHEMBL55217544248449BindingDB-show
CHEMBL55231344248572BindingDB-show
CHEMBL55236244248570BindingDB-show
CHEMBL55237625066366BindingDB-show
CHEMBL55237725066365BindingDB-show
CHEMBL55391844248573BindingDB-show
CHEMBL55958325064908BindingDB-show
CHEMBL55958525064907BindingDB-show
CHEMBL56131025066364BindingDB-show
CHEMBL56131125064052BindingDB-show
CHEMBL56131224795059BindingDB-show
CHEMBL56171525064905BindingDB-show
CHEMBL56211425065109BindingDB-show
CHEMBL56237325064904BindingDB-show
CHEMBL56237444248698BindingDB-show
CHEMBL56285025064054BindingDB-show
CHEMBL56317744248811BindingDB-show
CHEMBL56334325064485BindingDB-show
CHEMBL56340725065111BindingDB-show
CHEMBL56451044248571BindingDB-show
CHEMBL56489744248451BindingDB-show
CHEMBL56651145483015BindingDB-show
CHEMBL56651245483016BindingDB-show
CHEMBL56911845485508BindingDB-show
CHEMBL56913244555419BindingDB-show
CHEMBL57031045269910BindingDB-show
CHEMBL57091745485502BindingDB-show
CHEMBL57107245485482BindingDB-show
CHEMBL57113645485532BindingDB-show
CHEMBL57114945485513BindingDB-show
CHEMBL57136245485515BindingDB-show
CHEMBL57138845485461BindingDB-show
CHEMBL57160145485460BindingDB-show
CHEMBL57181445485487BindingDB-show
CHEMBL57202745485521BindingDB-show
CHEMBL57224144555421BindingDB-show
CHEMBL57224445485558BindingDB-show
CHEMBL57278044479197BindingDB-show
CHEMBL57292645483036BindingDB-show
CHEMBL57294721496278BindingDB-show
CHEMBL57297945483008BindingDB-show
CHEMBL57298020348772BindingDB-show
CHEMBL57298211391583BindingDB-show
CHEMBL57371444478926BindingDB-show
CHEMBL57371544247751BindingDB-show
CHEMBL57393444479459BindingDB-show
CHEMBL57393544479701BindingDB-show
CHEMBL57393644479199BindingDB-show
CHEMBL57437044479460BindingDB-show
CHEMBL57444445482997BindingDB-show
CHEMBL57444545482999BindingDB-show
CHEMBL57458944478925BindingDB-show
CHEMBL57460544479699BindingDB-show
CHEMBL57466645483018BindingDB-show
CHEMBL57532044626353BindingDB-show
CHEMBL57553444626354BindingDB-show
CHEMBL57588145482676BindingDB-show
CHEMBL57589544479457BindingDB-show
CHEMBL57589610155934BindingDB-show
CHEMBL57594645483022BindingDB-show
CHEMBL57594745483023BindingDB-show
CHEMBL57671045485514BindingDB-show
CHEMBL57676244479458BindingDB-show
CHEMBL57679045485485BindingDB-show
CHEMBL57817644555417BindingDB-show
CHEMBL57841245485486BindingDB-show
CHEMBL57902645485520BindingDB-show
CHEMBL57906744479198BindingDB-show
CHEMBL57906844479702BindingDB-show
CHEMBL58281245485477BindingDB-show
CHEMBL58358844626352BindingDB-show
CHEMBL58367045485463BindingDB-show
CHEMBL58367345485476BindingDB-show
CHEMBL58377145482998BindingDB-show
CHEMBL58412244478924BindingDB-show
CHEMBL58414744479703BindingDB-show
CHEMBL58436544478927BindingDB-show
CHEMBL58455911335940BindingDB-show
CHEMBL58537644479700BindingDB-show
CHEMBL59034311697504BindingDB-show
CHEMBL60294946184724BindingDB-show
CHEMBL60365625183768BindingDB-show
CHEMBL60576411640694BindingDB-show
CHEMBL7716344315244BindingDB-show
CHEMBL7725810565532BindingDB-show
CHEMBL7799544315333BindingDB-show
CHEMBL7800110854279BindingDB-show
CHEMBL7823344315155BindingDB-show
CID 1129417911294179BindingDB-show
CID 1145268511625778BindingDB-show
CP-271485448940DrugBank-show
Dichloromethylenebisphosphonate25419BindingDB-show
Essigsaeure176DrugBank-show
Grassystatin A44255320BindingDB-show
Ilomastat132519BindingDB-show
Peakdale1_0005433649035BindingDB-show
phenylhydantoin1002BindingDB-show
pyrazolopyridine, 4925022681BindingDB-show
thiadiazole derivative, 3424754251BindingDB-show
WAY0336852146BindingDB-show
ZINC001113962741314BindingDB-show
ZINC001324052801266BindingDB-show
Synonyms:
HME
Macrophage elastase
Macrophage metalloelastase
Matrix metalloproteinase-12
ME
MMP-12
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
MMP12_MOUSE74.160.6
MMP3_RABIT68.850.8
MMP3_HUMAN68.751.4
MMP10_HUMAN67.449.7
MMP3_MOUSE67.250.7
MMP3_CANFA65.749.5
MMP1_HUMAN63.948.5
MMP1_RABIT63.849.1
MMP8_HUMAN63.646.8
MMP13_HUMAN60.846.3
MMP13_RAT60.245
MMP13_MOUSE59.644.5
MMP11_MOUSE44.731.6
MMP16_HUMAN43.329.4
MMP14_HUMAN42.832
MMP28_HUMAN42.129.2
MMP2_HUMAN41.430
MMP2_MOUSE4129.6
MMP2_RAT40.929.7
MMP7_HUMAN34.726.5
MMP9_HUMAN34.722.8
MMP9_CANFA34.522.8
MMP9_RAT34.123.4
MMP9_MOUSE33.122.8
GDIA_BOVIN32.417.7
TYTR_CRIFA3217.3
IIGP1_MOUSE31.619.1
OMPF_ECOLI31.318.7
TBB_CANAL31.318.4
Q59GL9_HUMAN31.216.8
Protein-Protein Interactions:
No data available