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Target Details

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Name:Mitogen-activated protein kinase 12
Uniprot name:MK12_HUMAN
Accession Numbers:P53778 Q14260 Q99588 Q99672
EC-Number:2.7.11.24
Organism:Homo sapiens
Human
PDB IDs:1CM8
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
3bx511427975BindingDB-show
ABT-86911485656BindingDB-show
ADENYLYL IMIDODIPHOSPHATE33113DrugBank-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL108986525052767BindingDB-show
CHEMBL12092889811100BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL21580316046126BindingDB-show
CHEMBL50724944591740BindingDB-show
CHEMBL51458216047143BindingDB-show
CHEMBL56193244517743BindingDB-show
CHEMBL59759246228508BindingDB-show
CHEMBL59862646228822BindingDB-show
CHEMBL60212346228951BindingDB-show
CHIR-26511656518BindingDB-show
CID 99267919818231BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Kinome_248146224684BindingDB-show
Kinome_26559952773BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_71446886323BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
PHOSPHONOTHREONINE3246323DrugBank-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Pyrazoleanthrone8515BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB 203580176155BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
ERK-6
ERK5
Extracellular signal-regulated kinase 6
MAP kinase p38 gamma
Mitogen-activated protein kinase 12
Mitogen-activated protein kinase p38 gamma
Stress-activated protein kinase 3
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
MK14_HUMAN75.760.2
MK14_MOUSE75.760.2
Q499G7_HUMAN60.639.9
MK01_HUMAN60.640.2
Q1HBJ4_HUMAN60.640.2
MK01_RAT60.440.2
MK01_MOUSE60.440.2
MK03_RAT58.139.6
MK03_MOUSE57.438.8
MK03_HUMAN56.337.9
MK10_HUMAN5236.8
CDK6_HUMAN47.231.4
A4D1G0_HUMAN47.231.4
CSK21_HUMAN45.225.7
CDK7_HUMAN44.729.2
CDK2_HUMAN44.129.4
CDK1_HUMAN43.929.4
CDK9_HUMAN43.427.7
CSK2A_MAIZE4324.6
MSK1_TOBAC42.726.9
CDK5_HUMAN41.627.6
CDK5_MOUSE41.627.6
CDC2H_PLAFK41.329.8
C4R3V7_PICPG41.328.5
KAPCG_HUMAN40.621.9
GSK3B_HUMAN40.424.3
KAPCA_MOUSE40.320.5
GSK3B_MOUSE40.224.1
Q5KU03_MOUSE40.224.1
B5BUC0_HUMAN4024.3
Protein-Protein Interactions: