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Target Details

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Name:ERK-2
Uniprot name:MK01_MOUSE
Accession Numbers:P27703 P63085 Q3V1U6
EC-Number:2.7.11.24
Organism:Mouse
Mus musculus
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3c5330800BindingDB-show
1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3f5330804BindingDB-show
2′-Amino-3′-methoxyflavone4713PROMISCUOUSPMID 10945876show
4-(FLUOROPHENYL)-1-CYCLOPROPYLMETHYL-5-(2-AMINO-4-PYRIMIDINYL)IMIDAZOLE5172BindingDB-show
4-[5-(4-fluorophenyl)-3-piperidin-4-ylimidazol-4-yl]pyrimidin-2-amine5164BindingDB-show
BATIMASTAT5362422PROMISCUOUSPMID 15277330show
CHEMBL17894510185160BindingDB-show
CHEMBL229789819930BindingDB-show
CHEMBL35948610302405BindingDB-show
CHEMBL36030410143584BindingDB-show
CHEMBL36841610163439BindingDB-show
CHEMBL36889510209082BindingDB-show
CHEMBL42658710187378BindingDB-show
CHEMBL53819045271731BindingDB-show
CHEMBL55065845270882BindingDB-show
CHEMBL55232444241600BindingDB-show
CHEMBL55240745270066BindingDB-show
CHEMBL55953845268325BindingDB-show
CHEMBL55959145269114BindingDB-show
CHEMBL55959245269116BindingDB-show
CHEMBL55973445268326BindingDB-show
CHEMBL55973545268327BindingDB-show
CHEMBL56052145268224BindingDB-show
CHEMBL56078745269195BindingDB-show
CHEMBL56264845272600BindingDB-show
CHEMBL56396145269115BindingDB-show
CHEMBL56396244241599BindingDB-show
Digitoflavone5280445PROMISCUOUSPMID 12145106show
DKI5330812BindingDB-show
Olomoucine4592BindingDB-show
RWJ-3872525330790BindingDB-show
SB 203580176155BindingDB-show
sb2169955171BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
Succinonitrile, bis(amino(o-aminophenylthio)methylene)-3006531PROMISCUOUS2 PMIDsshow
Tiludronate60937PROMISCUOUSPMID 15922088show
Synonyms:
ERK-2
ERT1
Extracellular signal-regulated kinase 2
MAP kinase 2
MAPK 2
Mitogen-activated protein kinase 1
Mitogen-activated protein kinase 2
p42-MAPK
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
MK01_RAT100100
MK01_HUMAN98.998.6
Q1HBJ4_HUMAN98.998.6
Q499G7_HUMAN98.698.1
MK03_HUMAN88.182.3
MK03_MOUSE87.781.6
MK03_RAT87.781.6
MK14_HUMAN64.145.7
MK14_MOUSE63.845.7
MK12_HUMAN60.440.2
MK10_HUMAN48.331.8
CDK6_HUMAN46.731.4
A4D1G0_HUMAN46.731.4
MSK1_TOBAC46.626.9
CDK2_HUMAN46.631.4
CDK7_HUMAN45.433.2
CDC2H_PLAFK44.432
CDK1_HUMAN44.230.4
CDK5_MOUSE43.829.2
CDK5_HUMAN43.429.1
CDK4_HUMAN42.929.1
GSK3B_HUMAN42.627.1
CDK9_HUMAN42.529.7
CSK2A_MAIZE42.524.9
Q5KU03_MOUSE42.427.1
GSK3B_MOUSE42.427.1
B5BUC0_HUMAN42.126.8
C4R3V7_PICPG41.827.7
CDK4_RAT41.728.3
CSK21_HUMAN41.525
Protein-Protein Interactions:
No data available