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Target Details

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Name:Hepatocyte growth factor receptor
Uniprot name:MET_HUMAN
Accession Numbers:O60366 P08581 Q12875 Q9UDX7 Q9UPL8
EC-Number:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1FYR 1R0P 1R1W 1SHY 1SSL 1UX3 2G15 2RFN 2RFS 2UZX 2UZY 2WD1 2WGJ 3BUX 3CE3 3CTH 3CTJ 3EFJ 3EFK 3F66 3F82
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(-)-Epicatechin-3-gallate107905BindingDB-show
(-)-Gallocatechin gallate199472BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
3cth17748441BindingDB-show
3ctj11560856BindingDB-show
7MP10062694BindingDB-show
877399-52-511626560BindingDB-show
ABT-86911485656BindingDB-show
AC1MGBXT2933553BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Bio2_0004136610353BindingDB-show
BMS-53692410390396BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:54743644560358BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL1016839797919BindingDB-show
CHEMBL107672122353185BindingDB-show
CHEMBL107729111580208BindingDB-show
CHEMBL108090246865325BindingDB-show
CHEMBL108551124762205BindingDB-show
CHEMBL108667546889273BindingDB-show
CHEMBL108667625055103BindingDB-show
CHEMBL108673646880951BindingDB-show
CHEMBL108693225055102BindingDB-show
CHEMBL108765046880136BindingDB-show
CHEMBL108798446889250BindingDB-show
CHEMBL108853946889251BindingDB-show
CHEMBL108911646885625BindingDB-show
CHEMBL109275444541014BindingDB-show
CHEMBL109440824993189BindingDB-show
CHEMBL109471825055101BindingDB-show
CHEMBL109503425054857BindingDB-show
CHEMBL109503525268137BindingDB-show
CHEMBL109503646888807BindingDB-show
CHEMBL109535646888808BindingDB-show
CHEMBL109535746888809BindingDB-show
CHEMBL109535846888810BindingDB-show
CHEMBL109535946888811BindingDB-show
CHEMBL109536046888812BindingDB-show
CHEMBL109536146888813BindingDB-show
CHEMBL109562644605035BindingDB-show
CHEMBL109562744605037BindingDB-show
CHEMBL109587316223008BindingDB-show
CHEMBL109651916222087BindingDB-show
CHEMBL109653616221868BindingDB-show
CHEMBL109654916221977BindingDB-show
CHEMBL109714116223108BindingDB-show
CHEMBL109714216223106BindingDB-show
CHEMBL109754316223221BindingDB-show
CHEMBL109754416223315BindingDB-show
CHEMBL109782425055344BindingDB-show
CHEMBL109786816221866BindingDB-show
CHEMBL109786916223110BindingDB-show
CHEMBL109815725055104BindingDB-show
CHEMBL109815846888806BindingDB-show
CHEMBL109817616223402BindingDB-show
CHEMBL109821316223006BindingDB-show
CHEMBL109847546887997BindingDB-show
CHEMBL109851716222089BindingDB-show
CHEMBL109851816222081BindingDB-show
CHEMBL109917416223116BindingDB-show
CHEMBL109917516223215BindingDB-show
CHEMBL109917616223313BindingDB-show
CHEMBL109920416223223BindingDB-show
CHEMBL116979349798500BindingDB-show
CHEMBL116979449798502BindingDB-show
CHEMBL116979549798504BindingDB-show
CHEMBL117000949798480BindingDB-show
CHEMBL117001049798482BindingDB-show
CHEMBL117017149798364BindingDB-show
CHEMBL117017249798366BindingDB-show
CHEMBL117030349798362BindingDB-show
CHEMBL117051449798411BindingDB-show
CHEMBL117060749798414BindingDB-show
CHEMBL117060849798416BindingDB-show
CHEMBL117081749798417BindingDB-show
CHEMBL117092649798476BindingDB-show
CHEMBL117102549798478BindingDB-show
CHEMBL117122449798412BindingDB-show
CHEMBL117194146911482BindingDB-show
CHEMBL117213149798506BindingDB-show
CHEMBL117270449798451BindingDB-show
CHEMBL117270549798452BindingDB-show
CHEMBL117270649798453BindingDB-show
CHEMBL117270749798455BindingDB-show
CHEMBL117295746898022BindingDB-show
CHEMBL11825810005638BindingDB-show
CHEMBL11841944345639BindingDB-show
CHEMBL1201859826083BindingDB-show
CHEMBL12140544346053BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL124320046929748BindingDB-show
CHEMBL125891311847343BindingDB-show
CHEMBL127023024809764BindingDB-show
CHEMBL127039946868971BindingDB-show
CHEMBL127211649765254BindingDB-show
CHEMBL127217149840306BindingDB-show
CHEMBL20151111530963BindingDB-show
CHEMBL20537211525727BindingDB-show
CHEMBL21208444414322BindingDB-show
CHEMBL21361816043304BindingDB-show
CHEMBL21374344414347BindingDB-show
CHEMBL23333844432441BindingDB-show
CHEMBL23757024180608BindingDB-show
CHEMBL24628410217590BindingDB-show
CHEMBL24635617748275BindingDB-show
CHEMBL24810810151881BindingDB-show
CHEMBL25178011699573BindingDB-show
CHEMBL25178211504995BindingDB-show
CHEMBL25179544446940BindingDB-show
CHEMBL25179644446941BindingDB-show
CHEMBL25198011555216BindingDB-show
CHEMBL25221311627441BindingDB-show
CHEMBL25221421081515BindingDB-show
CHEMBL25241521081489BindingDB-show
CHEMBL25241621081481BindingDB-show
CHEMBL25322221081793BindingDB-show
CHEMBL25322311546617BindingDB-show
CHEMBL25329224882503BindingDB-show
CHEMBL25344421081519BindingDB-show
CHEMBL25365621081488BindingDB-show
CHEMBL25365744447645BindingDB-show
CHEMBL25388121081523BindingDB-show
CHEMBL25388221081480BindingDB-show
CHEMBL25405010165455BindingDB-show
CHEMBL25408544447647BindingDB-show
CHEMBL25408611504713BindingDB-show
CHEMBL25426944446930BindingDB-show
CHEMBL25428011713579BindingDB-show
CHEMBL25428144447643BindingDB-show
CHEMBL25487911497322BindingDB-show
CHEMBL25489525032700BindingDB-show
CHEMBL25490711620642BindingDB-show
CHEMBL25509111699504BindingDB-show
CHEMBL25509211642366BindingDB-show
CHEMBL2819579869943BindingDB-show
CHEMBL3523089850161BindingDB-show
CHEMBL37080811517688BindingDB-show
CHEMBL39861044443314BindingDB-show
CHEMBL39967411670702BindingDB-show
CHEMBL39969844447640BindingDB-show
CHEMBL39971011703607BindingDB-show
CHEMBL39992021081576BindingDB-show
CHEMBL40033221081792BindingDB-show
CHEMBL40055611584471BindingDB-show
CHEMBL40072621081514BindingDB-show
CHEMBL40134411555957BindingDB-show
CHEMBL4123679871380BindingDB-show
CHEMBL41399621081484BindingDB-show
CHEMBL41940910295633BindingDB-show
CHEMBL42894444447646BindingDB-show
CHEMBL42949021081490BindingDB-show
CHEMBL43002611613348BindingDB-show
CHEMBL43002721081520BindingDB-show
CHEMBL43869611678254BindingDB-show
CHEMBL44587116040697BindingDB-show
CHEMBL44731725178328BindingDB-show
CHEMBL44761644564667BindingDB-show
CHEMBL44827616717966BindingDB-show
CHEMBL44899344564669BindingDB-show
CHEMBL44975744564665BindingDB-show
CHEMBL45361316040363BindingDB-show
CHEMBL45565544564666BindingDB-show
CHEMBL45645644581399BindingDB-show
CHEMBL45650244581670BindingDB-show
CHEMBL45672044581671BindingDB-show
CHEMBL45672244581674BindingDB-show
CHEMBL45733844581758BindingDB-show
CHEMBL45733944581759BindingDB-show
CHEMBL45799944581710BindingDB-show
CHEMBL45821644581712BindingDB-show
CHEMBL45821744581713BindingDB-show
CHEMBL45835225148929BindingDB-show
CHEMBL45844011688423BindingDB-show
CHEMBL45844125148935BindingDB-show
CHEMBL45887444581756BindingDB-show
CHEMBL45907844581757BindingDB-show
CHEMBL45932544581336BindingDB-show
CHEMBL45947844565222BindingDB-show
CHEMBL45989211510244BindingDB-show
CHEMBL46094411654729BindingDB-show
CHEMBL46111811626442BindingDB-show
CHEMBL46111911612145BindingDB-show
CHEMBL46112011655658BindingDB-show
CHEMBL46199811591094BindingDB-show
CHEMBL46202344564591BindingDB-show
CHEMBL46216811398307BindingDB-show
CHEMBL46217111583264BindingDB-show
CHEMBL46218311717068BindingDB-show
CHEMBL46223144564592BindingDB-show
CHEMBL46223244564593BindingDB-show
CHEMBL46235711517264BindingDB-show
CHEMBL46235824886446BindingDB-show
CHEMBL46250444581333BindingDB-show
CHEMBL46250544581334BindingDB-show
CHEMBL46266716041065BindingDB-show
CHEMBL46270725212175BindingDB-show
CHEMBL46270844581372BindingDB-show
CHEMBL46271144581208BindingDB-show
CHEMBL46271225113181BindingDB-show
CHEMBL46283516040527BindingDB-show
CHEMBL46291444581209BindingDB-show
CHEMBL46421116040525BindingDB-show
CHEMBL46440944564752BindingDB-show
CHEMBL46451044565164BindingDB-show
CHEMBL46513044565165BindingDB-show
CHEMBL46513116042706BindingDB-show
CHEMBL46579044581370BindingDB-show
CHEMBL46579144581371BindingDB-show
CHEMBL46757444581294BindingDB-show
CHEMBL46878744581293BindingDB-show
CHEMBL47255211510560BindingDB-show
CHEMBL47353318528548BindingDB-show
CHEMBL47781724766030BindingDB-show
CHEMBL48827125178540BindingDB-show
CHEMBL48864624894992BindingDB-show
CHEMBL48881124894997BindingDB-show
CHEMBL48908325178539BindingDB-show
CHEMBL48932644565117BindingDB-show
CHEMBL49096544565118BindingDB-show
CHEMBL49270544573178BindingDB-show
CHEMBL49270644573179BindingDB-show
CHEMBL49276044573169BindingDB-show
CHEMBL49276144573170BindingDB-show
CHEMBL49291244573233BindingDB-show
CHEMBL49316944219632BindingDB-show
CHEMBL49331344573124BindingDB-show
CHEMBL49331444573125BindingDB-show
CHEMBL49332144573180BindingDB-show
CHEMBL49351044573123BindingDB-show
CHEMBL49351144573174BindingDB-show
CHEMBL49351942601406BindingDB-show
CHEMBL49422144219633BindingDB-show
CHEMBL49961823153333BindingDB-show
CHEMBL49987821081500BindingDB-show
CHEMBL49988521081728BindingDB-show
CHEMBL49988621081475BindingDB-show
CHEMBL50015725196404BindingDB-show
CHEMBL50042225195745BindingDB-show
CHEMBL50092144586566BindingDB-show
CHEMBL50223221081503BindingDB-show
CHEMBL50228344586643BindingDB-show
CHEMBL50253144586731BindingDB-show
CHEMBL50254421081471BindingDB-show
CHEMBL50262144564670BindingDB-show
CHEMBL50301644564668BindingDB-show
CHEMBL50323625148932BindingDB-show
CHEMBL50352444564664BindingDB-show
CHEMBL50685144573238BindingDB-show
CHEMBL50814221081472BindingDB-show
CHEMBL50839516040698BindingDB-show
CHEMBL50877616041238BindingDB-show
CHEMBL51011211340470BindingDB-show
CHEMBL51045944581709BindingDB-show
CHEMBL51067616040699BindingDB-show
CHEMBL51097344573173BindingDB-show
CHEMBL51117244581711BindingDB-show
CHEMBL51159244581292BindingDB-show
CHEMBL51261644581295BindingDB-show
CHEMBL51360244581673BindingDB-show
CHEMBL51462416260214BindingDB-show
CHEMBL51565942604837BindingDB-show
CHEMBL51632844581243BindingDB-show
CHEMBL51746916040526BindingDB-show
CHEMBL51791244581210BindingDB-show
CHEMBL51820944565221BindingDB-show
CHEMBL51835711719648BindingDB-show
CHEMBL51851124886674BindingDB-show
CHEMBL51851644581335BindingDB-show
CHEMBL51867644564707BindingDB-show
CHEMBL52163944573175BindingDB-show
CHEMBL52164544573122BindingDB-show
CHEMBL52200944573242BindingDB-show
CHEMBL52215544573177BindingDB-show
CHEMBL52334144573234BindingDB-show
CHEMBL52385344573172BindingDB-show
CHEMBL52402144573235BindingDB-show
CHEMBL52418144573237BindingDB-show
CHEMBL52436421081477BindingDB-show
CHEMBL52504925196406BindingDB-show
CHEMBL52526021081469BindingDB-show
CHEMBL52692925196402BindingDB-show
CHEMBL53893222028181BindingDB-show
CHEMBL54074445272467BindingDB-show
CHEMBL54957145269953BindingDB-show
CHEMBL54982645270590BindingDB-show
CHEMBL54998045269959BindingDB-show
CHEMBL55010445271585BindingDB-show
CHEMBL55015845272464BindingDB-show
CHEMBL55016045272468BindingDB-show
CHEMBL55030545271586BindingDB-show
CHEMBL55065145270769BindingDB-show
CHEMBL55085745270775BindingDB-show
CHEMBL55145845270780BindingDB-show
CHEMBL55157045272300BindingDB-show
CHEMBL55190644219665BindingDB-show
CHEMBL55199345269918BindingDB-show
CHEMBL55199845269945BindingDB-show
CHEMBL55219545269946BindingDB-show
CHEMBL55449744189142BindingDB-show
CHEMBL55451045271584BindingDB-show
CHEMBL55611845270766BindingDB-show
CHEMBL55621545272498BindingDB-show
CHEMBL55659645268038BindingDB-show
CHEMBL55662745272502BindingDB-show
CHEMBL55683745272508BindingDB-show
CHEMBL55749144219667BindingDB-show
CHEMBL55830645273339BindingDB-show
CHEMBL55992645268213BindingDB-show
CHEMBL56024545267171BindingDB-show
CHEMBL56044645267177BindingDB-show
CHEMBL56057545269054BindingDB-show
CHEMBL56105845267312BindingDB-show
CHEMBL56118045269092BindingDB-show
CHEMBL56118145269093BindingDB-show
CHEMBL56125645267314BindingDB-show
CHEMBL56125845267346BindingDB-show
CHEMBL56146145267350BindingDB-show
CHEMBL56158345269098BindingDB-show
CHEMBL56166025229537BindingDB-show
CHEMBL56186445267357BindingDB-show
CHEMBL56206345267361BindingDB-show
CHEMBL56294344219666BindingDB-show
CHEMBL56295845268190BindingDB-show
CHEMBL56308045273165BindingDB-show
CHEMBL56325745273175BindingDB-show
CHEMBL56335645267342BindingDB-show
CHEMBL56355545272290BindingDB-show
CHEMBL56373145269922BindingDB-show
CHEMBL56436545267176BindingDB-show
CHEMBL56437145272463BindingDB-show
CHEMBL56444045273344BindingDB-show
CHEMBL56467945268916BindingDB-show
CHEMBL56476045272515BindingDB-show
CHEMBL56482745269056BindingDB-show
CHEMBL56482845269085BindingDB-show
CHEMBL56490445270783BindingDB-show
CHEMBL56560345488054BindingDB-show
CHEMBL56578216041066BindingDB-show
CHEMBL56578545488073BindingDB-show
CHEMBL56580716042707BindingDB-show
CHEMBL56584345487864BindingDB-show
CHEMBL56599045488074BindingDB-show
CHEMBL56600345488044BindingDB-show
CHEMBL56601045488051BindingDB-show
CHEMBL56608345483170BindingDB-show
CHEMBL56621516041962BindingDB-show
CHEMBL56624245487862BindingDB-show
CHEMBL56625325065131BindingDB-show
CHEMBL56662145488043BindingDB-show
CHEMBL56662345488085BindingDB-show
CHEMBL56668325064072BindingDB-show
CHEMBL56668545487870BindingDB-show
CHEMBL56683616042894BindingDB-show
CHEMBL56684416040870BindingDB-show
CHEMBL56687525064730BindingDB-show
CHEMBL56708925064073BindingDB-show
CHEMBL56717445483147BindingDB-show
CHEMBL56739145483172BindingDB-show
CHEMBL56747545488014BindingDB-show
CHEMBL56813845102733BindingDB-show
CHEMBL56892211723489BindingDB-show
CHEMBL56988024883334BindingDB-show
CHEMBL57086945488076BindingDB-show
CHEMBL57104024883287BindingDB-show
CHEMBL57238924967007BindingDB-show
CHEMBL57291045483166BindingDB-show
CHEMBL57317745483159BindingDB-show
CHEMBL57376123652906BindingDB-show
CHEMBL57376245483404BindingDB-show
CHEMBL57376524966287BindingDB-show
CHEMBL57376845483457BindingDB-show
CHEMBL57397445483471BindingDB-show
CHEMBL57405024965938BindingDB-show
CHEMBL57409324966649BindingDB-show
CHEMBL57412524967006BindingDB-show
CHEMBL57422545483533BindingDB-show
CHEMBL57423045483535BindingDB-show
CHEMBL57440645483426BindingDB-show
CHEMBL57458845482700BindingDB-show
CHEMBL57461345482750BindingDB-show
CHEMBL57462845483428BindingDB-show
CHEMBL57486345483391BindingDB-show
CHEMBL57486445483392BindingDB-show
CHEMBL57487045483519BindingDB-show
CHEMBL57507645483393BindingDB-show
CHEMBL57549045483425BindingDB-show
CHEMBL57556545483155BindingDB-show
CHEMBL57556645483157BindingDB-show
CHEMBL57569845483464BindingDB-show
CHEMBL57571245483443BindingDB-show
CHEMBL57571345483445BindingDB-show
CHEMBL57650445488075BindingDB-show
CHEMBL57675245483534BindingDB-show
CHEMBL57676945483444BindingDB-show
CHEMBL57688723401001BindingDB-show
CHEMBL57698923400934BindingDB-show
CHEMBL57736945483526BindingDB-show
CHEMBL57774216043068BindingDB-show
CHEMBL57860110246246BindingDB-show
CHEMBL58292545483427BindingDB-show
CHEMBL58292724967008BindingDB-show
CHEMBL58470116041961BindingDB-show
CHEMBL58520516041234BindingDB-show
CHEMBL58529325064510BindingDB-show
CHEMBL59145746232552BindingDB-show
CHEMBL59192446232607BindingDB-show
CHEMBL59759246228508BindingDB-show
CHEMBL59775446233287BindingDB-show
CHEMBL59852346232509BindingDB-show
CHEMBL59862646228822BindingDB-show
CHEMBL59891246232512BindingDB-show
CHEMBL59922445139989BindingDB-show
CHEMBL59942845139991BindingDB-show
CHEMBL59999346232553BindingDB-show
CHEMBL60039846232636BindingDB-show
CHEMBL60060324967005BindingDB-show
CHEMBL60060424966651BindingDB-show
CHEMBL60063225054600BindingDB-show
CHEMBL60079546232443BindingDB-show
CHEMBL60212346228951BindingDB-show
CHEMBL60247046232554BindingDB-show
CHEMBL60247146232555BindingDB-show
CHEMBL60247246232556BindingDB-show
CHEMBL60270325054599BindingDB-show
CHEMBL60270425054601BindingDB-show
CHEMBL60290546232608BindingDB-show
CHEMBL60308244177697BindingDB-show
CHEMBL60348246228648BindingDB-show
CHEMBL60471210429593BindingDB-show
CHEMBL60873846232513BindingDB-show
CHEMBL61213744177803BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
EGCG65064BindingDB-show
epihematoxylol24949852BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Haematoxylin442514BindingDB-show
hematoxylene24949856BindingDB-show
hematoxylone44578561BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Inhibitor III9870238BindingDB-show
K1639_SIGMA3035817DrugBank-show
Kinome_248146224684BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
nchembio.90-comp111715767BindingDB-show
NVP-TAE68416038120BindingDB-show
Pazopanib10113978BindingDB-show
PHA-66575210461815BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Pyrrolo[2,3-d]pyrimidine 16539952BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1361_Selleck24901704BindingDB-show
S1363_Selleck11317348BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Triazolopyridazine, 10d24864825BindingDB-show
Triazolopyridazine, 10e24864993BindingDB-show
Triazolopyridazine, 10f24824705BindingDB-show
Triazolopyridazine, 10m24865175BindingDB-show
Triazolopyridazine, 424864821BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
c-Met
Hepatocyte growth factor receptor
HGF receptor
HGF/SF receptor
Met proto-oncogene tyrosine kinase
Scatter factor receptor
SF receptor
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
IGF1R_HUMAN31.519.1
INSR_HUMAN31.518.4
TOP2_YEAST30.916.7
JAK2_RAT30.218
JAK2_HUMAN29.918.5
RET_HUMAN29.718.4
BXB_CLOBO2917.1
TETX_CLOTE28.916
SYIC_HUMAN28.617.2
BLM_HUMAN28.517
CFTR_HUMAN28.315.5
SYEP_HUMAN28.316.1
ITAL_HUMAN28.216.7
Q9ZWQ6_ADICA27.915.6
AT1A1_PIG27.815
PARP1_CHICK27.815.3
P93098_CERPU27.816.4
AT1A1_SHEEP27.714.9
AT1A1_BOVIN27.714.9
TLR7_HUMAN27.715.9
ALK_HUMAN27.516.9
AT1A1_CANFA27.515.3
AT1A1_HUMAN27.515.3
AT1A1_MOUSE27.515.6
Q41460_SOLTU27.414.6
AT1A1_RABIT27.415.1
JAK3_RAT27.317.2
POL_SIVM127.214.6
PARP1_HUMAN27.115.5
PARP1_RAT27.115.2
Protein-Protein Interactions: