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Target Details

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Name:Arachidonate 15-lipoxygenase
Uniprot name:LOX15_HUMAN
Accession Numbers:A8K2P4 P16050 Q8N6R7 Q99657
EC-Number:1.13.11.33
Organism:Homo sapiens
Human
PDB IDs:2ABT
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(+)-(5S,8S,9R,10S)-20-Methoxypuupehenone637821BindingDB-show
1,6-bis[4-(2-methoxyphenyl)piperazin-1-yl]hexane-1,6-dione2931181BindingDB-show
2,3-Dihydro-6,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one173513BindingDB-show
2,4-DIBROMOPHENOL12005BindingDB-show
2,6-DIBROMOPHENOL11847BindingDB-show
3,5-dihydroxy-2-phenylchromen-4-one5393151BindingDB-show
3,6-Dihydroxyflavone688659BindingDB-show
3-BROMOPHENOL11563BindingDB-show
4',6,7-trihydroxy isoflavone5284649BindingDB-show
4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine47795BindingDB-show
4-Bromophenetole68523BindingDB-show
4-BROMOPHENOL7808BindingDB-show
6,7,4'-Trihydroxyisoflavan125101BindingDB-show
6,7,4'-Trihydroxyisoflavanone125100BindingDB-show
6-Monohydroxyflavone72279BindingDB-show
7-Chloro-2-((4-methoxyphenyl)methyl)-3-methyl-5-propyl-4-benzofuranol128132BindingDB-show
7-Hydroxyflavone5281894BindingDB-show
7-Hydroxyflavonol5393152BindingDB-show
AC1M3M3L2192753BindingDB-show
AC1MGATI2933060BindingDB-show
AC1NTNOL5407860BindingDB-show
AC1NTWJL5413054BindingDB-show
AC1NUKBF5481241BindingDB-show
AIDS087929476857BindingDB-show
AIDS087930476858BindingDB-show
Ambcb66359679586795BindingDB-show
Baicalein5281605BindingDB-show
BAS 00832362785627BindingDB-show
BAS 061776401082938BindingDB-show
BPE-53086109BindingDB-show
BROMOPHENOL7244BindingDB-show
CHEBI:47358344421356BindingDB-show
CHEMBL10450044421383BindingDB-show
CHEMBL116393846907573BindingDB-show
CHEMBL116393946907574BindingDB-show
CHEMBL116436946907602BindingDB-show
CHEMBL116524344557858BindingDB-show
CHEMBL116557746907572BindingDB-show
CHEMBL128955849821278BindingDB-show
CHEMBL14799910955008BindingDB-show
CHEMBL14850310348509BindingDB-show
CHEMBL15708210042678BindingDB-show
CHEMBL17242944384827BindingDB-show
CHEMBL17336844385415BindingDB-show
CHEMBL17380244384614BindingDB-show
CHEMBL17521623043596BindingDB-show
CHEMBL17531523043630BindingDB-show
CHEMBL17663444385224BindingDB-show
CHEMBL17668910316643BindingDB-show
CHEMBL17672844385537BindingDB-show
CHEMBL17692344385457BindingDB-show
CHEMBL17705544385459BindingDB-show
CHEMBL17709823043614BindingDB-show
CHEMBL17710010384947BindingDB-show
CHEMBL17717144385225BindingDB-show
CHEMBL17759823043622BindingDB-show
CHEMBL18094710179787BindingDB-show
CHEMBL18589344396187BindingDB-show
CHEMBL18609811093078BindingDB-show
CHEMBL18609910554258BindingDB-show
CHEMBL18675244396244BindingDB-show
CHEMBL18747244396194BindingDB-show
CHEMBL22167944421367BindingDB-show
CHEMBL23881244437720BindingDB-show
CHEMBL23881344437721BindingDB-show
CHEMBL23881444437722BindingDB-show
CHEMBL23881544437724BindingDB-show
CHEMBL23881644437725BindingDB-show
CHEMBL23882144437731BindingDB-show
CHEMBL23884321270161BindingDB-show
CHEMBL23884410936155BindingDB-show
CHEMBL23902244437727BindingDB-show
CHEMBL23902344437728BindingDB-show
CHEMBL23903024721289BindingDB-show
CHEMBL23903344437732BindingDB-show
CHEMBL23967721270186BindingDB-show
CHEMBL23989315628203BindingDB-show
CHEMBL24050511041857BindingDB-show
CHEMBL24071344437716BindingDB-show
CHEMBL24136444437718BindingDB-show
CHEMBL24136521831939BindingDB-show
CHEMBL24136623093378BindingDB-show
CHEMBL24179444437729BindingDB-show
CHEMBL24181433845371BindingDB-show
CHEMBL24181521270142BindingDB-show
CHEMBL24181644436891BindingDB-show
CHEMBL24534944440179BindingDB-show
CHEMBL24554744440180BindingDB-show
CHEMBL24594244440174BindingDB-show
CHEMBL24595214852609BindingDB-show
CHEMBL24636123656213BindingDB-show
CHEMBL26310444440176BindingDB-show
CHEMBL31494110937563BindingDB-show
CHEMBL3627619986835BindingDB-show
CHEMBL36741010020717BindingDB-show
CHEMBL39107910007601BindingDB-show
CHEMBL39258944440177BindingDB-show
CHEMBL39425744437723BindingDB-show
CHEMBL39425844437726BindingDB-show
CHEMBL39445944437715BindingDB-show
CHEMBL39511514983007BindingDB-show
CHEMBL39534644437717BindingDB-show
CHEMBL39667344437719BindingDB-show
CHEMBL39780344436892BindingDB-show
CHEMBL41335044384554BindingDB-show
CHEMBL41473144421374BindingDB-show
CHEMBL42077510045891BindingDB-show
CHEMBL42171044318030BindingDB-show
CHEMBL44242015135539BindingDB-show
CHEMBL45588023425708BindingDB-show
CHEMBL45694944584373BindingDB-show
CHEMBL45717144584380BindingDB-show
CHEMBL45918511740143BindingDB-show
CHEMBL46294211978695BindingDB-show
CHEMBL46457711952901BindingDB-show
CHEMBL50507311211821BindingDB-show
CHEMBL7910944318018BindingDB-show
CHEMBL7927544318019BindingDB-show
CHEMBL7940244460480BindingDB-show
CHEMBL8158311741221BindingDB-show
CHEMBL8184844460420BindingDB-show
CHEMBL8895244323089BindingDB-show
CHEMBL8927510905139BindingDB-show
CHEMBL8928310072931BindingDB-show
CHEMBL9221211142891BindingDB-show
CHEMBL9235910340455BindingDB-show
Chloropuupehenone9998777BindingDB-show
ciclopiroxolamine2749DrugBank-show
Ciclopiroxolamine38911DrugBank-show
ciclopiroxolamine2749SuperTarget-show
Ciclopiroxolamine38911SuperTarget-show
CID 1028337910283379BindingDB-show
CID 1087432910874329BindingDB-show
CID 1120389723662099BindingDB-show
CID 957724110396070BindingDB-show
Ethyl 2-(4-phenylbutanoylamino)benzoate836505BindingDB-show
flavonols11349BindingDB-show
Hyrtenone A637177BindingDB-show
igernellin9947690BindingDB-show
jaspaquinol10110469BindingDB-show
MLS00227654744142085BindingDB-show
neodysidenin15482063BindingDB-show
NORDIHYDROGUAIARETIC ACID4534BindingDB-show
Nordihyolroguaiaretic acid71398BindingDB-show
Nordihyolroguaiaretic acid71398DrugBank-show
NSC172033425241BindingDB-show
NSC292213324974BindingDB-show
NSC364753339231BindingDB-show
NSC600285156398BindingDB-show
NSC603663353995BindingDB-show
NSC611816356358BindingDB-show
NSC611817356359BindingDB-show
PARA-BROMOBENZYL ALCOHOL70119BindingDB-show
Phenidone7090BindingDB-show
Puupehedione460087BindingDB-show
puupehenone72536BindingDB-show
Rofecoxib5090PROMISCUOUSPMID 16904331show
SMR000035823663693BindingDB-show
SPONGIADIOXIN A10029508BindingDB-show
Spongiadioxin C636835BindingDB-show
ST029413727302BindingDB-show
STK0034501346428BindingDB-show
STK184320801015BindingDB-show
STK232605771546BindingDB-show
STK2592541141363BindingDB-show
STK267357883201BindingDB-show
STK3903461072992BindingDB-show
Suberanilohydroxamic acid5311PROMISCUOUSPMID 15574791show
Superfustel5281614BindingDB-show
Tetrabromobisphenol A6618BindingDB-show
Texasin5281812BindingDB-show
Tribromobisphenol A80801BindingDB-show
Xanthaurine5280343BindingDB-show
ZILEUTON60490DrugBank-show
ZINC001330025713107BindingDB-show
ZINC00464460889785BindingDB-show
ZINC008166441095055BindingDB-show
ZINC011285961304061BindingDB-show
ZINC011556271325172BindingDB-show
ZINC020851921743704BindingDB-show
ZINC135078425317326BindingDB-show
Synonyms:
15-LOX
Arachidonate 15-lipoxygenase
Arachidonate omega-6 lipoxygenase
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
LOX15_RABIT9081.1
LOX12_HUMAN79.665.5
LOX5_HUMAN60.239.7
LOX5_MOUSE60.139.3
LOX5_RAT59.839.1
LX12B_HUMAN53.834.2
B1ASX6_MOUSE53.636.2
LOXE3_HUMAN5335.6
LOX3_SOYBN3321.5
AOSL_PLEHO32.219.7
FSHR_HUMAN30.316.1
CHK1_SCHPO30.317.2
Q8VVD2_GEOSE30.118.4
12S_PROFR29.818.1
FHUA_ECOLI29.417.3
HTPG_ECOLI29.319.1
Q8GR64_PSEPU29.316.3
PROD_HUMAN29.318.4
FOLC_HUMAN29.318.7
IKKA_HUMAN29.217.1
MTHR_HUMAN29.214.7
PAO_MAIZE29.117.9
SYSC_HUMAN28.917.3
ACPH_HUMAN28.918.4
SPTC2_HUMAN28.916.4
IF2P_METTH28.715.5
CP4A2_RAT28.716.6
UVRB_THET828.716.1
Q6L8F0_THETH28.715.7
PSD2_HUMAN28.617.3
Protein-Protein Interactions:
No data available