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Target Details

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Name:Arachidonate 12-lipoxygenase, 12S-type
Uniprot name:LOX12_HUMAN
Accession Numbers:O95569 P18054 Q6ISF8 Q9UQM4
EC-Number:1.13.11.31
Organism:Homo sapiens
Human
PDB IDs:2ABU 3D3L
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(+)-(5S,8S,9R,10S)-20-Methoxypuupehenone637821BindingDB-show
1,6-bis[4-(2-methoxyphenyl)piperazin-1-yl]hexane-1,6-dione2931181BindingDB-show
2,3-Dihydro-6,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one173513BindingDB-show
2,4-DIBROMOPHENOL12005BindingDB-show
2,6-DIBROMOPHENOL11847BindingDB-show
3,5-dihydroxy-2-phenylchromen-4-one5393151BindingDB-show
3,6-Dihydroxyflavone688659BindingDB-show
3-((N-(Aminocarbonyl)-N-hydroxyamino)methyl)-6-phenoxychromene131820BindingDB-show
3-BROMOPHENOL11563BindingDB-show
4',6,7-trihydroxy isoflavone5284649BindingDB-show
4-Bromophenetole68523BindingDB-show
4-BROMOPHENOL7808BindingDB-show
6,7,4'-Trihydroxyisoflavan125101BindingDB-show
6,7,4'-Trihydroxyisoflavanone125100BindingDB-show
6-Monohydroxyflavone72279BindingDB-show
7-Hydroxyflavone5281894BindingDB-show
7-Hydroxyflavonol5393152BindingDB-show
AC1M3M3L2192753BindingDB-show
AC1MGATI2933060BindingDB-show
AC1NTNOL5407860BindingDB-show
AC1NTWJL5413054BindingDB-show
AC1NUKBF5481241BindingDB-show
AIDS087929476857BindingDB-show
AIDS087930476858BindingDB-show
Ambcb66359679586795BindingDB-show
Baicalein5281605BindingDB-show
BAS 00832362785627BindingDB-show
BAS 061776401082938BindingDB-show
BROMOPHENOL7244BindingDB-show
CGS 24891195771BindingDB-show
CHEMBL116393846907573BindingDB-show
CHEMBL116393946907574BindingDB-show
CHEMBL116436946907602BindingDB-show
CHEMBL116524344557858BindingDB-show
CHEMBL116557746907572BindingDB-show
CHEMBL127011344460122BindingDB-show
CHEMBL127022044460123BindingDB-show
CHEMBL127031244460112BindingDB-show
CHEMBL127031449788946BindingDB-show
CHEMBL127060844460139BindingDB-show
CHEMBL127081044460130BindingDB-show
CHEMBL127111644460128BindingDB-show
CHEMBL127122044460114BindingDB-show
CHEMBL128955849821278BindingDB-show
CHEMBL14799910955008BindingDB-show
CHEMBL14850310348509BindingDB-show
CHEMBL18094710179787BindingDB-show
CHEMBL18589344396187BindingDB-show
CHEMBL18609811093078BindingDB-show
CHEMBL18609910554258BindingDB-show
CHEMBL18675244396244BindingDB-show
CHEMBL18747244396194BindingDB-show
CHEMBL23881244437720BindingDB-show
CHEMBL23881344437721BindingDB-show
CHEMBL23881444437722BindingDB-show
CHEMBL23881544437724BindingDB-show
CHEMBL23881644437725BindingDB-show
CHEMBL23882144437731BindingDB-show
CHEMBL23884321270161BindingDB-show
CHEMBL23884410936155BindingDB-show
CHEMBL23902244437727BindingDB-show
CHEMBL23902344437728BindingDB-show
CHEMBL23903024721289BindingDB-show
CHEMBL23903344437732BindingDB-show
CHEMBL23967721270186BindingDB-show
CHEMBL23989315628203BindingDB-show
CHEMBL24050511041857BindingDB-show
CHEMBL24071344437716BindingDB-show
CHEMBL24136444437718BindingDB-show
CHEMBL24136521831939BindingDB-show
CHEMBL24136623093378BindingDB-show
CHEMBL24179444437729BindingDB-show
CHEMBL24181433845371BindingDB-show
CHEMBL24181521270142BindingDB-show
CHEMBL24181644436891BindingDB-show
CHEMBL31494110937563BindingDB-show
CHEMBL3627619986835BindingDB-show
CHEMBL39107910007601BindingDB-show
CHEMBL39425744437723BindingDB-show
CHEMBL39425844437726BindingDB-show
CHEMBL39445944437715BindingDB-show
CHEMBL39511514983007BindingDB-show
CHEMBL39534644437717BindingDB-show
CHEMBL39667344437719BindingDB-show
CHEMBL39780344436892BindingDB-show
CHEMBL45588023425708BindingDB-show
CHEMBL45694944584373BindingDB-show
CHEMBL45918511740143BindingDB-show
CHEMBL50507311211821BindingDB-show
CHEMBL8895244323089BindingDB-show
CHEMBL8927510905139BindingDB-show
CHEMBL8928310072931BindingDB-show
CHEMBL9221211142891BindingDB-show
CHEMBL9235910340455BindingDB-show
Chloropuupehenone9998777BindingDB-show
CID 957724110396070BindingDB-show
Ethyl 2-(4-phenylbutanoylamino)benzoate836505BindingDB-show
flavonols11349BindingDB-show
Hyrtenone A637177BindingDB-show
neodysidenin15482063BindingDB-show
NORDIHYDROGUAIARETIC ACID4534BindingDB-show
Nordihyolroguaiaretic acid71398BindingDB-show
NSC172033425241BindingDB-show
NSC292213324974BindingDB-show
NSC364753339231BindingDB-show
NSC600285156398BindingDB-show
NSC603663353995BindingDB-show
NSC611816356358BindingDB-show
NSC611817356359BindingDB-show
PARA-BROMOBENZYL ALCOHOL70119BindingDB-show
Phenidone7090BindingDB-show
Phthalhydroquinone289PROMISCUOUSPMID 16171776show
Puupehedione460087BindingDB-show
puupehenone72536BindingDB-show
SMR000035823663693BindingDB-show
SPONGIADIOXIN A10029508BindingDB-show
Spongiadioxin C636835BindingDB-show
ST029413727302BindingDB-show
STK0034501346428BindingDB-show
STK184320801015BindingDB-show
STK232605771546BindingDB-show
STK2592541141363BindingDB-show
STK267357883201BindingDB-show
STK3903461072992BindingDB-show
Superfustel5281614BindingDB-show
Tetrabromobisphenol A6618BindingDB-show
Texasin5281812BindingDB-show
Tribromobisphenol A80801BindingDB-show
Xanthaurine5280343BindingDB-show
ZILEUTON60490BindingDB-show
ZINC001330025713107BindingDB-show
ZINC00464460889785BindingDB-show
ZINC008166441095055BindingDB-show
ZINC011285961304061BindingDB-show
ZINC011556271325172BindingDB-show
ZINC020851921743704BindingDB-show
ZINC024007711998811BindingDB-show
ZINC135078425317326BindingDB-show
Synonyms:
12-LOX
Arachidonate 12-lipoxygenase, 12S-type
Platelet-type lipoxygenase 12
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
LOX15_HUMAN79.665.5
LOX15_RABIT77.461.6
LOX5_MOUSE60.740.9
LOX5_HUMAN60.441.8
LOX5_RAT60.140.4
LX12B_HUMAN55.736.8
LOXE3_HUMAN54.236.5
B1ASX6_MOUSE53.435.6
LOX3_SOYBN35.521.7
AOSL_PLEHO33.321.1
PCKGC_HUMAN32.519.8
STAT1_HUMAN30.917.7
ALBU_BOVIN30.618.5
IKKB_HUMAN30.518.9
ACE_DROME3018.1
EAA2_HUMAN29.716.7
AMO_ECOLI29.716.4
TOP1M_HUMAN29.617.2
CACB1_HUMAN29.618
HEM0_HUMAN29.418.4
DNLJ_ENTFA29.415.5
TGM2_BOVIN29.218.9
Q8N6H3_HUMAN29.218
LAC1_MELAO29.118
PCKGM_CHICK2918
GBRR1_HUMAN28.915.5
PDE5A_CANFA28.916.1
TRXR2_HUMAN28.717.5
PDE5A_HUMAN28.716
Q8CHM5_MOUSE28.617.4
Protein-Protein Interactions: