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Target Details

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Name:cAMP-dependent protein kinase catalytic subunit alpha
Uniprot name:KAPCA_MOUSE
Accession Numbers:P05132 Q9JID0
EC-Number:2.7.11.11
Organism:Mouse
Mus musculus
PDB IDs:1APM 1ATP 1BKX 1BX6 1FMO 1J3H 1JBP 1JLU 1L3R 1PVK 1RDQ 1RE8 1REJ 1REK 1SYK 2CPK 2ERZ 2QCS 2QUR 2QVS 3FHI 3FJQ
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
()-oxazepam hemisuccinate sodium salt25190768BindingDB-show
()-oxazepam hemisuccinate sodium salt25190769BindingDB-show
()-oxazepam hemisuccinate sodium salt25190790BindingDB-show
()-oxazepam hemisuccinate sodium salt16121514BindingDB-show
()-oxazepam hemisuccinate sodium salt25190791BindingDB-show
()-oxazepam hemisuccinate sodium salt44282246BindingDB-show
()-oxazepam hemisuccinate sodium salt44282442BindingDB-show
()-oxazepam hemisuccinate sodium salt44282443BindingDB-show
()-oxazepam hemisuccinate sodium salt44282377BindingDB-show
()-oxazepam hemisuccinate sodium salt44282232BindingDB-show
()-oxazepam hemisuccinate sodium salt44282376BindingDB-show
()-oxazepam hemisuccinate sodium salt44282430BindingDB-show
()-oxazepam hemisuccinate sodium salt44282245BindingDB-show
()-oxazepam hemisuccinate sodium salt44282233BindingDB-show
()-oxazepam hemisuccinate sodium salt44282230BindingDB-show
(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE448043BindingDB-show
2-METHYL-2,4-PENTANEDIOL5288834DrugBank-show
Arabinosyladenine191BindingDB-show
BALANOL5287736DrugBank-show
Balanol analog 25327919DrugBank-show
BALANOL ANALOG 8448327DrugBank-show
CHEBI:14831444282203BindingDB-show
CHEBI:14835044282231BindingDB-show
CHEMBL17894510185160BindingDB-show
CHEMBL29739425190767BindingDB-show
CHEMBL35948610302405BindingDB-show
CHEMBL36030410143584BindingDB-show
CHEMBL36841610163439BindingDB-show
CHEMBL36889510209082BindingDB-show
CHEMBL42658710187378BindingDB-show
CHEMBL44767825190789BindingDB-show
CHEMBL44983425190785BindingDB-show
CHEMBL45017925141061BindingDB-show
CHEMBL45026025190781BindingDB-show
CHEMBL45422525190782BindingDB-show
CHEMBL46551825190786BindingDB-show
CHEMBL49508825190784BindingDB-show
CHEMBL49576625190765BindingDB-show
CHEMBL49576725190773BindingDB-show
CHEMBL49614125190778BindingDB-show
CHEMBL49636525190772BindingDB-show
CHEMBL49780025190777BindingDB-show
CHEMBL49892425190771BindingDB-show
CHEMBL50098925190783BindingDB-show
CHEMBL50170625190766BindingDB-show
CHEMBL50594925190770BindingDB-show
CHEMBL50633125190788BindingDB-show
CHEMBL50941125190787BindingDB-show
CHEMBL51022125190779BindingDB-show
CHEMBL52155125190774BindingDB-show
CHEMBL52289925190780BindingDB-show
CHEMBL52340125190776BindingDB-show
CHEMBL52373825190775BindingDB-show
Fasudil hydrochloride3547BindingDB-show
HYDROXYFASUDIL3064778BindingDB-show
HYDROXYFASUDIL3064778DrugBank-show
L-Cysteine, mercaptoethanol mixed disulfide170018DrugBank-show
Methylheptane356DrugBank-show
N-(2-(4-Bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide449241BindingDB-show
N-(2-(4-Bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide449241PROMISCUOUSPMID 15062850show
nchembio.95-comp183501PROMISCUOUSPMID 16248886show
Phosphatidalserine68841DrugBank-show
PHOSPHONOTHREONINE3246323DrugBank-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
Succinonitrile, bis(amino(o-aminophenylthio)methylene)-3006531PROMISCUOUSPMID 11640885show
Tetrahydrocannabinols2977PROMISCUOUSPMID 9260875show
Tetrahydrocannabinols16078PROMISCUOUSPMID 9260875show
Valerylaldehyde8063DrugBank-show
Vidarabine6713976BindingDB-show
y-27632448042BindingDB-show
Synonyms:
cAMP-dependent protein kinase catalytic subunit alpha
PKA C-alpha
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
KAPCA_HUMAN99.498
KAPCA_RAT99.199.1
KAPCA_PIG99.197.4
KAPCA_BOVIN98.997.7
KAPCB_HUMAN95.292
KAPCB_MOUSE94.391.5
KAPCB_RAT94.391.5
KAPCG_HUMAN91.581.5
KAPA_YEAST60.140.6
MK14_MOUSE4320.4
MK14_HUMAN42.720.4
AKT1_MOUSE42.728.7
AKT1_HUMAN42.528.5
MAPK2_HUMAN41.124.1
MK12_HUMAN40.320.5
MAPK2_CRILO39.924
MK01_HUMAN39.122.4
MK01_MOUSE39.122.5
MK01_RAT39.122.5
Q1HBJ4_HUMAN39.122.4
Q499G7_HUMAN38.622.2
MP2K2_HUMAN37.520.8
MP2K3_MOUSE37.422.1
CDK9_HUMAN37.419.4
MK03_RAT37.121.7
MK03_MOUSE37.121.7
MP2K2_MOUSE3719.8
MP2K6_MOUSE36.721.7
STK6_HUMAN36.421.3
PIM1_FELCA36.421.4
Protein-Protein Interactions:
No data available