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Target Details

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Name:Activator protein 1
Uniprot name:JUN_HUMAN
Accession Numbers:P05412 Q96G93
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:1A02 1FOS 1JNM 1JUN 1S9K 1T2K
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
()-oxazepam hemisuccinate sodium salt52943160BindingDB-show
AR-434/4329483211842418BindingDB-show
Arsentrioxide518740DrugBank-show
Arsentrioxide14888DrugBank-show
CHEMBL109350316752764BindingDB-show
CHEMBL124153446933420BindingDB-show
CHEMBL124207046932984BindingDB-show
CHEMBL124251946933276BindingDB-show
CHEMBL124252025017847BindingDB-show
CHEMBL124279546933278BindingDB-show
CHEMBL12805310525196BindingDB-show
CHEMBL12831410552343BindingDB-show
CHEMBL12842610622840BindingDB-show
CHEMBL12859810716536BindingDB-show
CHEMBL12859910813496BindingDB-show
CHEMBL12870810574991BindingDB-show
CHEMBL12880810574522BindingDB-show
CHEMBL13100610740841BindingDB-show
CHEMBL13100710811870BindingDB-show
CHEMBL13124610741644BindingDB-show
CHEMBL13129310786213BindingDB-show
CHEMBL13245710717756BindingDB-show
CHEMBL13249510407641BindingDB-show
CHEMBL18335944396341BindingDB-show
CHEMBL18336044396342BindingDB-show
CHEMBL18336144396343BindingDB-show
CHEMBL18602544396311BindingDB-show
CHEMBL18602644396339BindingDB-show
CHEMBL18617844396355BindingDB-show
CHEMBL18627844396345BindingDB-show
CHEMBL18639344396356BindingDB-show
CHEMBL18644844396340BindingDB-show
CHEMBL18660044396344BindingDB-show
CHEMBL18694244396309BindingDB-show
CHEMBL18974944396354BindingDB-show
CHEMBL19829611702600BindingDB-show
CHEMBL19932511502176BindingDB-show
CHEMBL20003111495735BindingDB-show
CHEMBL20006111696956BindingDB-show
CHEMBL20107911516540BindingDB-show
CHEMBL24533444440222BindingDB-show
CHEMBL24533544440223BindingDB-show
CHEMBL24533644440225BindingDB-show
CHEMBL24553444440227BindingDB-show
CHEMBL24553511560956BindingDB-show
CHEMBL24572411538129BindingDB-show
CHEMBL24572544440214BindingDB-show
CHEMBL24573244440229BindingDB-show
CHEMBL24573344440230BindingDB-show
CHEMBL24592544440216BindingDB-show
CHEMBL24593544440234BindingDB-show
CHEMBL24593644440236BindingDB-show
CHEMBL24654344440217BindingDB-show
CHEMBL24654444440219BindingDB-show
CHEMBL24654544440220BindingDB-show
CHEMBL24817616129582BindingDB-show
CHEMBL24837044440161BindingDB-show
CHEMBL24902944443382BindingDB-show
CHEMBL25047444443385BindingDB-show
CHEMBL26251410716588BindingDB-show
CHEMBL29017644290017BindingDB-show
CHEMBL29020244289467BindingDB-show
CHEMBL29065644289830BindingDB-show
CHEMBL29505044289913BindingDB-show
CHEMBL29519244289751BindingDB-show
CHEMBL29550844289821BindingDB-show
CHEMBL29620244289744BindingDB-show
CHEMBL29669544289832BindingDB-show
CHEMBL29689644289768BindingDB-show
CHEMBL29742044290016BindingDB-show
CHEMBL29784244289470BindingDB-show
CHEMBL29824544289703BindingDB-show
CHEMBL29841844289850BindingDB-show
CHEMBL3365469910975BindingDB-show
CHEMBL33765610666813BindingDB-show
CHEMBL33893410666814BindingDB-show
CHEMBL33946210787015BindingDB-show
CHEMBL34016510716177BindingDB-show
CHEMBL34041010499355BindingDB-show
CHEMBL34077910763720BindingDB-show
CHEMBL36083844396310BindingDB-show
CHEMBL36106744396370BindingDB-show
CHEMBL36277544396307BindingDB-show
CHEMBL36457044396308BindingDB-show
CHEMBL36481944396326BindingDB-show
CHEMBL37144611589029BindingDB-show
CHEMBL38012111682452BindingDB-show
CHEMBL39179444440235BindingDB-show
CHEMBL39261344440218BindingDB-show
CHEMBL39261444440221BindingDB-show
CHEMBL39261544440224BindingDB-show
CHEMBL39365944440226BindingDB-show
CHEMBL39386144440228BindingDB-show
CHEMBL39753144440215BindingDB-show
CHEMBL39931744443402BindingDB-show
CHEMBL39996544443369BindingDB-show
CHEMBL40088844443376BindingDB-show
CHEMBL40147944443383BindingDB-show
CHEMBL41302844289723BindingDB-show
CHEMBL41662744290028BindingDB-show
CHEMBL4200044289858BindingDB-show
CHEMBL4207944289771BindingDB-show
CHEMBL42128010624842BindingDB-show
CHEMBL4216744289849BindingDB-show
CHEMBL4220444289904BindingDB-show
CHEMBL4223544290086BindingDB-show
CHEMBL42315010741998BindingDB-show
CHEMBL4250344289752BindingDB-show
CHEMBL4254744290015BindingDB-show
CHEMBL42647711617865BindingDB-show
CHEMBL4265044289780BindingDB-show
CHEMBL42683811551589BindingDB-show
CHEMBL4268744289817BindingDB-show
CHEMBL4271944289488BindingDB-show
CHEMBL4281544289729BindingDB-show
CHEMBL4295244241655BindingDB-show
CHEMBL4315844289728BindingDB-show
CHEMBL43171844289916BindingDB-show
CHEMBL4319944289516BindingDB-show
CHEMBL4325144289501BindingDB-show
CHEMBL4325944289549BindingDB-show
CHEMBL4338844289710BindingDB-show
CHEMBL4345144289452BindingDB-show
CHEMBL4353444289772BindingDB-show
CHEMBL435499863590BindingDB-show
CHEMBL4355044289873BindingDB-show
CHEMBL4360644289917BindingDB-show
CHEMBL4361044289781BindingDB-show
CHEMBL4361944289831BindingDB-show
CHEMBL4408944289731BindingDB-show
CHEMBL44183010764421BindingDB-show
CHEMBL4452544289907BindingDB-show
CHEMBL4526144289806BindingDB-show
CHEMBL4650944289889BindingDB-show
CHEMBL4705344289672BindingDB-show
CHEMBL48590442632173BindingDB-show
CHEMBL48733625017848BindingDB-show
CHEMBL51527642631933BindingDB-show
CHEMBL51889844576207BindingDB-show
CHEMBL530049907138BindingDB-show
CHEMBL56400945267090BindingDB-show
Irbesartan3749DrugBank-show
Kinome_302211846124BindingDB-show
Mono-tertiarybutylhydroquinone16043PROMISCUOUSPMID 15390080show
Nincaluicolflastine13342DrugBank-show
NSC-23818744559321BindingDB-show
NSC716802402628BindingDB-show
Pergularinine264751BindingDB-show
Resveratrol445154PROMISCUOUSPMID 10843709show
Schuttgelb3220PROMISCUOUSPMID 16959273show
Tylophorinidine161749BindingDB-show
Synonyms:
Activator protein 1
AP1
p39
Proto-oncogene c-jun
Transcription factor AP-1
V-jun avian sarcoma virus 17 oncogene homolog
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
JUN_MOUSE97.696.4
JUN_RAT97.395.8
BIEA_HUMAN35.318.6
PHNX_BACCE35.219.3
GCN4_YEAST33.220.4
CREB1_HUMAN33.220.3
P5CR2_HUMAN32.521
CMAS2_MYCBO32.419.9
CMAS2_MYCTU32.419.9
TGT_ZYMMO32.119
PPAC_BACSU31.817.6
Q9WYV8_THEMA31.816.2
C6ELL5_ECOBD31.517.8
HEM2_ECOLI31.517.8
PDXY_ECOLI31.315.9
HIS8_THEMA31.316.9
RPOA_ECOLI31.315.2
PER59_ARATH31.216.3
Q9KIE5_STRHY31.218
NADC_SALTY3116.6
RSGA_THEMA30.717.4
LACI_ECOLI30.616.1
KITH_HHV1130.616.9
SYW2_DEIRA30.616.5
AK1C2_HUMAN30.518.6
LIAS_BOVIN30.318.3
LIPB_CANAR30.320.8
P5CR1_HUMAN30.319.1
MTDC_HUMAN30.217.7
PSUG_THEMA30.116.4
Protein-Protein Interactions:
Uniprot nameSource
ZHANG_HUMANPMID 12805554
VRK1_HUMAN2 PMIDs
VDR_HUMAN3 PMIDs
UBIQ_HUMAN3 PMIDs
UBC9_HUMAN4 PMIDs
TRIP4_HUMAN5 PMIDs
TOP2A_HUMAN6 PMIDs
TOP1_HUMAN7 PMIDs
TGIF1_HUMAN8 PMIDs
TF7L2_HUMAN9 PMIDs
TCF20_HUMAN10 PMIDs
T22D3_HUMAN11 PMIDs
SYSC_HUMAN12 PMIDs
SUMO4_HUMAN13 PMIDs
SUMO3_HUMAN14 PMIDs
SUMO2_HUMAN15 PMIDs
SUMO1_HUMAN16 PMIDs
STF1_HUMAN17 PMIDs
STAT4_HUMAN18 PMIDs
STAT3_HUMAN19 PMIDs
STAT1_HUMAN20 PMIDs
SPIB_HUMAN21 PMIDs
SPI1_HUMAN22 PMIDs
SP1_HUMAN23 PMIDs
SOX8_HUMAN24 PMIDs
SOX10_HUMAN25 PMIDs
SNRK_HUMAN26 PMIDs
SNPC5_HUMAN27 PMIDs
SMRD1_HUMAN28 PMIDs
SMAD4_HUMAN29 PMIDs
SMAD4_HUMAN30 PMIDs
SMAD3_HUMAN31 PMIDs
SMAD3_HUMAN32 PMIDs
SMAD2_HUMAN33 PMIDs
SKI_HUMAN34 PMIDs
RUNX2_HUMAN35 PMIDs
RUNX1_HUMAN36 PMIDs
RS27A_HUMAN36 PMIDs
RL40_HUMAN36 PMIDs
RL18A_HUMAN37 PMIDs
RFWD2_HUMAN38 PMIDs
RBM39_HUMAN39 PMIDs
PP4C_HUMAN40 PMIDs
PP2BB_HUMAN41 PMIDs
PO2F1_HUMAN42 PMIDs
PML_HUMAN43 PMIDs
PKHO1_HUMAN44 PMIDs
PIT1_HUMAN45 PMIDs
PIN1_HUMAN46 PMIDs
PIAS1_HUMAN47 PMIDs
PHX2A_HUMAN48 PMIDs
PACS1_HUMAN49 PMIDs
NTRK3_HUMAN50 PMIDs
NRIP1_HUMAN51 PMIDs
NFYA_HUMAN52 PMIDs
NFAC2_HUMAN53 PMIDs
NFAC2_HUMAN54 PMIDs
NF2L2_HUMAN55 PMIDs
NF2L1_HUMAN56 PMIDs
NACA_HUMAN57 PMIDs
MYOD1_HUMAN58 PMIDs
MOK_HUMAN59 PMIDs
MK10_HUMAN60 PMIDs
MK09_HUMAN61 PMIDs
MBB1A_HUMAN62 PMIDs
MAPK5_HUMAN63 PMIDs
MAF_HUMAN64 PMIDs
MAFK_HUMAN65 PMIDs
MAFG_HUMAN66 PMIDs
MAFB_HUMAN67 PMIDs
JUN_HUMAN68 PMIDs
JUND_HUMAN69 PMIDs
JUNB_HUMAN70 PMIDs
JDP2_HUMAN71 PMIDs
ITF2_HUMAN72 PMIDs
ITCH_HUMAN73 PMIDs
IBP7_HUMAN74 PMIDs
HXC8_HUMAN75 PMIDs
HXA9_HUMAN76 PMIDs
HMGA1_HUMAN77 PMIDs
HME1_HUMAN78 PMIDs
HLF_HUMAN79 PMIDs
HIF1A_HUMAN80 PMIDs
HHEX_HUMAN81 PMIDs
HELC1_HUMAN82 PMIDs
HCFC1_HUMAN83 PMIDs
GSK3B_HUMAN84 PMIDs
GCR_HUMAN85 PMIDs
GCR_HUMAN86 PMIDs
GATA2_HUMAN87 PMIDs
FOS_HUMAN88 PMIDs
FOS_HUMAN89 PMIDs
FOS_HUMAN90 PMIDs
FOS_HUMAN91 PMIDs
FOS_HUMAN92 PMIDs
FOS_HUMAN93 PMIDs
FOSL2_HUMAN94 PMIDs
FOSL1_HUMAN95 PMIDs
FOSB_HUMAN96 PMIDs
FBXW7_HUMAN97 PMIDs
ETS2_HUMAN98 PMIDs
ETS2_HUMAN99 PMIDs
ETS1_HUMAN100 PMIDs
ESR1_HUMAN101 PMIDs
ERG_HUMAN102 PMIDs
ERG_HUMAN103 PMIDs
EP300_HUMAN104 PMIDs
ELOF1_HUMAN105 PMIDs
ELF3_HUMAN106 PMIDs
EGR1_HUMAN107 PMIDs
EDF1_HUMAN108 PMIDs
DDX21_HUMAN109 PMIDs
DDIT3_HUMAN110 PMIDs
DBP_HUMAN111 PMIDs
CSN5_HUMAN112 PMIDs
CSK22_HUMAN113 PMIDs
CSK21_HUMAN114 PMIDs
CREM_HUMAN115 PMIDs
CREB5_HUMAN116 PMIDs
CITE1_HUMAN117 PMIDs
CEBPE_HUMAN118 PMIDs
BTG1_HUMAN119 PMIDs
BCL6_HUMAN120 PMIDs
BCL3_HUMAN121 PMIDs
BATF_HUMAN122 PMIDs
BATF3_HUMAN123 PMIDs
BACH2_HUMAN124 PMIDs
ATF7_HUMAN125 PMIDs
ATF4_HUMAN126 PMIDs
ATF3_HUMAN127 PMIDs
ASCC2_HUMAN128 PMIDs
ASCC1_HUMAN129 PMIDs
ANDR_HUMAN130 PMIDs
ABL1_HUMAN131 PMIDs
1433F_HUMAN132 PMIDs