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Target Details

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Name:JAK-3
Uniprot name:JAK3_HUMAN
Accession Numbers:P52333 Q13259 Q13260 Q13611 Q99699 Q9Y6S2
EC-Number:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1YVJ
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2ofv15991573BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
4-anilinoquinazoline deriv. 24708BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
aminoquinazoline benzamide, 316086088BindingDB-show
AST-48711409972BindingDB-show
Bio2_0004136610353BindingDB-show
Brivanib11234052BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:65304644419562BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEBI:67937245486164BindingDB-show
CHEMBL10406244336174BindingDB-show
CHEMBL1040749796455BindingDB-show
CHEMBL10440944335986BindingDB-show
CHEMBL10464044335927BindingDB-show
CHEMBL10496344335773BindingDB-show
CHEMBL10525544335843BindingDB-show
CHEMBL10657144335857BindingDB-show
CHEMBL10694444335968BindingDB-show
CHEMBL10696144335832BindingDB-show
CHEMBL10716644335938BindingDB-show
CHEMBL10727344335946BindingDB-show
CHEMBL107622146879483BindingDB-show
CHEMBL107670046880785BindingDB-show
CHEMBL107757525062228BindingDB-show
CHEMBL107784146882802BindingDB-show
CHEMBL107784225063021BindingDB-show
CHEMBL107800525059112BindingDB-show
CHEMBL107815925062765BindingDB-show
CHEMBL107816525062226BindingDB-show
CHEMBL107816625060146BindingDB-show
CHEMBL107822825059626BindingDB-show
CHEMBL107822925061949BindingDB-show
CHEMBL107827425061685BindingDB-show
CHEMBL107827546882470BindingDB-show
CHEMBL107827646882471BindingDB-show
CHEMBL107827746882472BindingDB-show
CHEMBL107836325062498BindingDB-show
CHEMBL107836425060927BindingDB-show
CHEMBL107837025063023BindingDB-show
CHEMBL107845325061950BindingDB-show
CHEMBL107868846882539BindingDB-show
CHEMBL107868946882540BindingDB-show
CHEMBL107872025063025BindingDB-show
CHEMBL107872125061435BindingDB-show
CHEMBL107876746882541BindingDB-show
CHEMBL107886646882542BindingDB-show
CHEMBL107888946882590BindingDB-show
CHEMBL107893346882803BindingDB-show
CHEMBL107893425060922BindingDB-show
CHEMBL107897146882589BindingDB-show
CHEMBL107907746882591BindingDB-show
CHEMBL107907846882592BindingDB-show
CHEMBL107912025060677BindingDB-show
CHEMBL107912125059891BindingDB-show
CHEMBL107952346879420BindingDB-show
CHEMBL107952446879421BindingDB-show
CHEMBL107952546879422BindingDB-show
CHEMBL107952646879423BindingDB-show
CHEMBL107959345375955BindingDB-show
CHEMBL107959445375956BindingDB-show
CHEMBL108011046879484BindingDB-show
CHEMBL108011146879485BindingDB-show
CHEMBL108015946865431BindingDB-show
CHEMBL108032246880193BindingDB-show
CHEMBL108032346880194BindingDB-show
CHEMBL108033246880196BindingDB-show
CHEMBL108033346880197BindingDB-show
CHEMBL108119011951225BindingDB-show
CHEMBL108129024800423BindingDB-show
CHEMBL108129124800604BindingDB-show
CHEMBL108129224800602BindingDB-show
CHEMBL108137646879545BindingDB-show
CHEMBL108137711844913BindingDB-show
CHEMBL108137846879546BindingDB-show
CHEMBL108137945375954BindingDB-show
CHEMBL108144324801650BindingDB-show
CHEMBL108148546880738BindingDB-show
CHEMBL108166346880739BindingDB-show
CHEMBL108184646880195BindingDB-show
CHEMBL108197524800776BindingDB-show
CHEMBL108197646880686BindingDB-show
CHEMBL108197724801129BindingDB-show
CHEMBL108197846880687BindingDB-show
CHEMBL108202246865430BindingDB-show
CHEMBL108202346880784BindingDB-show
CHEMBL108551124762205BindingDB-show
CHEMBL108723546880119BindingDB-show
CHEMBL108723646880120BindingDB-show
CHEMBL108842346880121BindingDB-show
CHEMBL108842446880122BindingDB-show
CHEMBL108885625123475BindingDB-show
CHEMBL108885725123807BindingDB-show
CHEMBL108977346865529BindingDB-show
CHEMBL108981346885231BindingDB-show
CHEMBL108981446885232BindingDB-show
CHEMBL108981546885234BindingDB-show
CHEMBL108983325123806BindingDB-show
CHEMBL109119046885052BindingDB-show
CHEMBL109119146885053BindingDB-show
CHEMBL109156525123154BindingDB-show
CHEMBL109206346885233BindingDB-show
CHEMBL109258825123474BindingDB-show
CHEMBL109284046885289BindingDB-show
CHEMBL109292546865530BindingDB-show
CHEMBL109292646398810BindingDB-show
CHEMBL109311946885290BindingDB-show
CHEMBL109319125123155BindingDB-show
CHEMBL109345425123808BindingDB-show
CHEMBL109346825123472BindingDB-show
CHEMBL109374925128110BindingDB-show
CHEMBL122163346934144BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL124297746929544BindingDB-show
CHEMBL124320046929748BindingDB-show
CHEMBL124332646929857BindingDB-show
CHEMBL125891311847343BindingDB-show
CHEMBL127023024809764BindingDB-show
CHEMBL128781252944839BindingDB-show
CHEMBL128785450878566BindingDB-show
CHEMBL128788352947304BindingDB-show
CHEMBL128791052942437BindingDB-show
CHEMBL128794052941228BindingDB-show
CHEMBL128794152948526BindingDB-show
CHEMBL128797120820292BindingDB-show
CHEMBL128800152943663BindingDB-show
CHEMBL128800252948550BindingDB-show
CHEMBL128803252948562BindingDB-show
CHEMBL128806252943672BindingDB-show
CHEMBL129074649838879BindingDB-show
CHEMBL1315779927718BindingDB-show
CHEMBL18514016723801BindingDB-show
CHEMBL2013079916282BindingDB-show
CHEMBL21212816086091BindingDB-show
CHEMBL21218116086078BindingDB-show
CHEMBL21218316086103BindingDB-show
CHEMBL21219516086117BindingDB-show
CHEMBL21295315991575BindingDB-show
CHEMBL21329016086115BindingDB-show
CHEMBL21347816086093BindingDB-show
CHEMBL21383116086107BindingDB-show
CHEMBL21449516086105BindingDB-show
CHEMBL21453016086116BindingDB-show
CHEMBL21455616086118BindingDB-show
CHEMBL21501916086102BindingDB-show
CHEMBL21569116086077BindingDB-show
CHEMBL21581311510392BindingDB-show
CHEMBL21586316086142BindingDB-show
CHEMBL21594316086114BindingDB-show
CHEMBL21595216086113BindingDB-show
CHEMBL21596916086099BindingDB-show
CHEMBL21793744419532BindingDB-show
CHEMBL21843944419475BindingDB-show
CHEMBL21857944419559BindingDB-show
CHEMBL21860244419499BindingDB-show
CHEMBL21874644419498BindingDB-show
CHEMBL22048344419524BindingDB-show
CHEMBL22048444419547BindingDB-show
CHEMBL22058544419523BindingDB-show
CHEMBL22096944419544BindingDB-show
CHEMBL22102944419491BindingDB-show
CHEMBL22103744419485BindingDB-show
CHEMBL22103844419522BindingDB-show
CHEMBL22137644419528BindingDB-show
CHEMBL22137844419556BindingDB-show
CHEMBL22191216126645BindingDB-show
CHEMBL22197644419492BindingDB-show
CHEMBL22202744419493BindingDB-show
CHEMBL22202844419527BindingDB-show
CHEMBL23173344432185BindingDB-show
CHEMBL23182144430898BindingDB-show
CHEMBL23182244430900BindingDB-show
CHEMBL23192544432193BindingDB-show
CHEMBL23194844432187BindingDB-show
CHEMBL23194944432188BindingDB-show
CHEMBL23203344430902BindingDB-show
CHEMBL23214716664854BindingDB-show
CHEMBL23214944432191BindingDB-show
CHEMBL23315144432177BindingDB-show
CHEMBL23355544432180BindingDB-show
CHEMBL23385444430914BindingDB-show
CHEMBL23385644430915BindingDB-show
CHEMBL23396944432183BindingDB-show
CHEMBL23406616216717BindingDB-show
CHEMBL23408619917815BindingDB-show
CHEMBL23429244430889BindingDB-show
CHEMBL23429325070618BindingDB-show
CHEMBL23471825070619BindingDB-show
CHEMBL23493644430894BindingDB-show
CHEMBL23493744430896BindingDB-show
CHEMBL24301544430903BindingDB-show
CHEMBL24301644430905BindingDB-show
CHEMBL24301844430910BindingDB-show
CHEMBL24517244430907BindingDB-show
CHEMBL24746811684933BindingDB-show
CHEMBL24786611626406BindingDB-show
CHEMBL31839044335849BindingDB-show
CHEMBL31955623532567BindingDB-show
CHEMBL32064644335848BindingDB-show
CHEMBL32185544335947BindingDB-show
CHEMBL3239949947841BindingDB-show
CHEMBL36462311153014BindingDB-show
CHEMBL37352344419516BindingDB-show
CHEMBL37432144419533BindingDB-show
CHEMBL37485444419515BindingDB-show
CHEMBL37507644419526BindingDB-show
CHEMBL37520544419548BindingDB-show
CHEMBL37529644419474BindingDB-show
CHEMBL37688544419481BindingDB-show
CHEMBL37773411632737BindingDB-show
CHEMBL38482044419502BindingDB-show
CHEMBL38494216086076BindingDB-show
CHEMBL38505516086108BindingDB-show
CHEMBL38511444419478BindingDB-show
CHEMBL38559816086106BindingDB-show
CHEMBL38666116086104BindingDB-show
CHEMBL38822044430909BindingDB-show
CHEMBL38822144430911BindingDB-show
CHEMBL38979744430904BindingDB-show
CHEMBL39109644432184BindingDB-show
CHEMBL39149244432179BindingDB-show
CHEMBL39237144432192BindingDB-show
CHEMBL39299844432190BindingDB-show
CHEMBL39337544432189BindingDB-show
CHEMBL39417444432182BindingDB-show
CHEMBL39619425070616BindingDB-show
CHEMBL39621344430901BindingDB-show
CHEMBL39644925070617BindingDB-show
CHEMBL39766344430895BindingDB-show
CHEMBL39766444430897BindingDB-show
CHEMBL42121344335985BindingDB-show
CHEMBL42471916086092BindingDB-show
CHEMBL42722616086101BindingDB-show
CHEMBL42723316086100BindingDB-show
CHEMBL45787125180101BindingDB-show
CHEMBL45833325154877BindingDB-show
CHEMBL45904444562721BindingDB-show
CHEMBL45976920111936BindingDB-show
CHEMBL46216811398307BindingDB-show
CHEMBL48041124963047BindingDB-show
CHEMBL49316944219632BindingDB-show
CHEMBL49422144219633BindingDB-show
CHEMBL50215625263033BindingDB-show
CHEMBL55079145269930BindingDB-show
CHEMBL55114044188627BindingDB-show
CHEMBL55710145273358BindingDB-show
CHEMBL55755945273361BindingDB-show
CHEMBL55770925069658BindingDB-show
CHEMBL55784645272482BindingDB-show
CHEMBL55811545273364BindingDB-show
CHEMBL55824145272486BindingDB-show
CHEMBL55978745269074BindingDB-show
CHEMBL56293425069976BindingDB-show
CHEMBL56358845273357BindingDB-show
CHEMBL56379545269072BindingDB-show
CHEMBL56494045267327BindingDB-show
CHEMBL56506645271570BindingDB-show
CHEMBL56879045486163BindingDB-show
CHEMBL56881544158660BindingDB-show
CHEMBL56881644159594BindingDB-show
CHEMBL56886645486119BindingDB-show
CHEMBL56901244159711BindingDB-show
CHEMBL56909145486120BindingDB-show
CHEMBL56909245486121BindingDB-show
CHEMBL56972045375974BindingDB-show
CHEMBL56972145486136BindingDB-show
CHEMBL56973745486106BindingDB-show
CHEMBL56973825171663BindingDB-show
CHEMBL56973944160079BindingDB-show
CHEMBL56975745486113BindingDB-show
CHEMBL56994845486138BindingDB-show
CHEMBL56995745486139BindingDB-show
CHEMBL56996645486142BindingDB-show
CHEMBL57000225171665BindingDB-show
CHEMBL57019245486168BindingDB-show
CHEMBL57020644158549BindingDB-show
CHEMBL57021744159001BindingDB-show
CHEMBL57022944158886BindingDB-show
CHEMBL57023045486157BindingDB-show
CHEMBL57023145486158BindingDB-show
CHEMBL57045645486159BindingDB-show
CHEMBL57046245486130BindingDB-show
CHEMBL57066845486109BindingDB-show
CHEMBL57068644159590BindingDB-show
CHEMBL57089042641406BindingDB-show
CHEMBL57089925171661BindingDB-show
CHEMBL57111845486147BindingDB-show
CHEMBL57111945486148BindingDB-show
CHEMBL57152645486169BindingDB-show
CHEMBL57606825172086BindingDB-show
CHEMBL57625725171666BindingDB-show
CHEMBL57627245486137BindingDB-show
CHEMBL57628625171877BindingDB-show
CHEMBL57647544159959BindingDB-show
CHEMBL57647644158553BindingDB-show
CHEMBL57648645486124BindingDB-show
CHEMBL57686245486170BindingDB-show
CHEMBL57794445486118BindingDB-show
CHEMBL57819425171876BindingDB-show
CHEMBL57820145486156BindingDB-show
CHEMBL58280844158658BindingDB-show
CHEMBL58303044159962BindingDB-show
CHEMBL58389544160207BindingDB-show
CHEMBL58405244605611BindingDB-show
CHEMBL58432244159839BindingDB-show
CHEMBL58494444159000BindingDB-show
CHEMBL58552745486129BindingDB-show
CHEMBL58592744622837BindingDB-show
CHEMBL59775446233287BindingDB-show
CHEMBL59922445139989BindingDB-show
CHEMBL59942845139991BindingDB-show
CHEMBL8732510658651BindingDB-show
CHIR-26511656518BindingDB-show
CID 1149662911696609BindingDB-show
CID 99267919818231BindingDB-show
CID 99267919966538BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Indolinone based inhibitor, 3d23644715BindingDB-show
JAK Inhibitor I5494425BindingDB-show
JAK3 Inhibitor I3794PROMISCUOUSPMID 18094329show
Kinome_248146224684BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_71446886323BindingDB-show
L2G9549184BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MASTPROM3795PROMISCUOUSPMID 18094329show
MLN805411712649BindingDB-show
oxindole i5908088BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
S2219_Selleck25062766BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
Staurosporine aglycone3815BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Tg-10134816722836BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
JAK-3
Janus kinase 3
L-JAK
Leukocyte janus kinase
Tyrosine-protein kinase JAK3
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
JAK3_MOUSE87.882.2
JAK3_RAT86.280
JAK2_HUMAN65.948.1
JAK2_RAT65.748
RET_HUMAN31.621.3
IGF1R_HUMAN31.219.5
DDR1_HUMAN31.121.4
P93098_CERPU30.919.3
KPCD1_HUMAN30.218.6
FGFR1_HUMAN3019.1
EMBC_MYCTU29.717.9
KPCD1_MOUSE29.618.7
EPHA2_HUMAN29.519.2
HXK2_RAT29.517.8
Q41460_SOLTU29.415.3
PDE3A_HUMAN29.218.1
TETX_CLOTE29.215.9
PUTA_ECOLI29.118.5
FLT3_HUMAN28.618.5
P94692_DESAF28.616.4
TOP2_CRIFA28.616.3
VGFR2_HUMAN28.418.9
RGYR_ARCFU28.416.5
FGFR1_MOUSE28.318.8
EGFR_HUMAN28.117.6
SYI_THET828.117.8
SYAM_HUMAN2818.6
METH_HUMAN2816.9
TLR9_HUMAN2819.1
CARB_ECOLI2815.9
Protein-Protein Interactions: