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Target Details

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Name:Kinase EMT
Uniprot name:ITK_HUMAN
Accession Numbers:B2R752 Q08881 Q32ML7
EC-Number:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1SM2 1SNU 1SNX 2E6I 2YUQ
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine449054BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
4-anilinoquinazoline deriv. 24708BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL109014346865419BindingDB-show
CHEMBL116352146906944BindingDB-show
CHEMBL116417346906711BindingDB-show
CHEMBL116417646906668BindingDB-show
CHEMBL116417746906712BindingDB-show
CHEMBL116426246906713BindingDB-show
CHEMBL116426446906788BindingDB-show
CHEMBL116430246906841BindingDB-show
CHEMBL116430846906942BindingDB-show
CHEMBL116435346871726BindingDB-show
CHEMBL116435446906839BindingDB-show
CHEMBL116435546906897BindingDB-show
CHEMBL116435646906790BindingDB-show
CHEMBL116435846906842BindingDB-show
CHEMBL116445346906898BindingDB-show
CHEMBL116445744250389BindingDB-show
CHEMBL116455746906941BindingDB-show
CHEMBL116455846906943BindingDB-show
CHEMBL116456546906977BindingDB-show
CHEMBL116456646906978BindingDB-show
CHEMBL116465646906979BindingDB-show
CHEMBL116475946907008BindingDB-show
CHEMBL116476046907010BindingDB-show
CHEMBL116541046906789BindingDB-show
CHEMBL116541746907009BindingDB-show
CHEMBL116550346906840BindingDB-show
CHEMBL116550746906899BindingDB-show
CHEMBL116561646906976BindingDB-show
CHEMBL116574446906710BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL128831552944965BindingDB-show
CHEMBL12883169899657BindingDB-show
CHEMBL12883179964850BindingDB-show
CHEMBL12883859813685BindingDB-show
CHEMBL128838652944969BindingDB-show
CHEMBL128838752946487BindingDB-show
CHEMBL12884789965035BindingDB-show
CHEMBL128847952946263BindingDB-show
CHEMBL128848052943834BindingDB-show
CHEMBL128855152948713BindingDB-show
CHEMBL128855252946806BindingDB-show
CHEMBL128855352946807BindingDB-show
CHEMBL128858249839480BindingDB-show
CHEMBL128858352946809BindingDB-show
CHEMBL128858452944368BindingDB-show
CHEMBL128861052946830BindingDB-show
CHEMBL128861152941966BindingDB-show
CHEMBL128861252941967BindingDB-show
CHEMBL12889749813405BindingDB-show
CHEMBL128897552948300BindingDB-show
CHEMBL128900552943432BindingDB-show
CHEMBL128900652942233BindingDB-show
CHEMBL128900752944088BindingDB-show
CHEMBL128972852948436BindingDB-show
CHEMBL128972952948437BindingDB-show
CHEMBL128973052942866BindingDB-show
CHEMBL129074649838879BindingDB-show
CHEMBL20441844410676BindingDB-show
CHEMBL20451544410662BindingDB-show
CHEMBL20462444410627BindingDB-show
CHEMBL20467544410417BindingDB-show
CHEMBL20467644410418BindingDB-show
CHEMBL20488844410415BindingDB-show
CHEMBL20554144410455BindingDB-show
CHEMBL20557244410577BindingDB-show
CHEMBL20558544410416BindingDB-show
CHEMBL20559944410622BindingDB-show
CHEMBL20563844410419BindingDB-show
CHEMBL20564144410567BindingDB-show
CHEMBL20568844410609BindingDB-show
CHEMBL20569144410420BindingDB-show
CHEMBL2057999806812BindingDB-show
CHEMBL2058619871955BindingDB-show
CHEMBL20595944410659BindingDB-show
CHEMBL20642444410430BindingDB-show
CHEMBL20690522170396BindingDB-show
CHEMBL20727244410741BindingDB-show
CHEMBL20732920635404BindingDB-show
CHEMBL20733144410737BindingDB-show
CHEMBL20773244410668BindingDB-show
CHEMBL20783044410614BindingDB-show
CHEMBL20816544410513BindingDB-show
CHEMBL20825444410612BindingDB-show
CHEMBL20825520635392BindingDB-show
CHEMBL20826544410613BindingDB-show
CHEMBL20835344410617BindingDB-show
CHEMBL20850144410461BindingDB-show
CHEMBL20852344410519BindingDB-show
CHEMBL20854144413100BindingDB-show
CHEMBL20854220635205BindingDB-show
CHEMBL20884620635236BindingDB-show
CHEMBL20886744412606BindingDB-show
CHEMBL20890120635510BindingDB-show
CHEMBL20900422170419BindingDB-show
CHEMBL20900922170403BindingDB-show
CHEMBL20905644412551BindingDB-show
CHEMBL20914811467730BindingDB-show
CHEMBL20916320635515BindingDB-show
CHEMBL20940022170436BindingDB-show
CHEMBL20988120635507BindingDB-show
CHEMBL21004644412771BindingDB-show
CHEMBL21012320635263BindingDB-show
CHEMBL21024322170398BindingDB-show
CHEMBL21024820635249BindingDB-show
CHEMBL21052820635412BindingDB-show
CHEMBL21059944412792BindingDB-show
CHEMBL21073510301758BindingDB-show
CHEMBL21093220635537BindingDB-show
CHEMBL21095344413088BindingDB-show
CHEMBL21098520635526BindingDB-show
CHEMBL21102122170411BindingDB-show
CHEMBL21103544413075BindingDB-show
CHEMBL21113620635501BindingDB-show
CHEMBL21129120635530BindingDB-show
CHEMBL21135520635514BindingDB-show
CHEMBL21160120635261BindingDB-show
CHEMBL21184220635534BindingDB-show
CHEMBL21199844413186BindingDB-show
CHEMBL21226910181704BindingDB-show
CHEMBL21594316086114BindingDB-show
CHEMBL23170844432433BindingDB-show
CHEMBL23174510217329BindingDB-show
CHEMBL23174744432425BindingDB-show
CHEMBL23192344432438BindingDB-show
CHEMBL23195810195108BindingDB-show
CHEMBL23195944432427BindingDB-show
CHEMBL23196044432428BindingDB-show
CHEMBL23215544432429BindingDB-show
CHEMBL23215710310880BindingDB-show
CHEMBL23236310230606BindingDB-show
CHEMBL23238110120124BindingDB-show
CHEMBL23238210288201BindingDB-show
CHEMBL23257910162990BindingDB-show
CHEMBL23258010310783BindingDB-show
CHEMBL23276910195646BindingDB-show
CHEMBL23296510110453BindingDB-show
CHEMBL23296610194689BindingDB-show
CHEMBL23316810163233BindingDB-show
CHEMBL23316910224336BindingDB-show
CHEMBL23333844432441BindingDB-show
CHEMBL23336510160476BindingDB-show
CHEMBL23336610114123BindingDB-show
CHEMBL23401810288395BindingDB-show
CHEMBL23401910195094BindingDB-show
CHEMBL23402010152000BindingDB-show
CHEMBL23439010165201BindingDB-show
CHEMBL23439210151801BindingDB-show
CHEMBL23459710195393BindingDB-show
CHEMBL27396644412550BindingDB-show
CHEMBL2819579869943BindingDB-show
CHEMBL37351344412537BindingDB-show
CHEMBL37735544412588BindingDB-show
CHEMBL37773411632737BindingDB-show
CHEMBL37775020635268BindingDB-show
CHEMBL37790620635267BindingDB-show
CHEMBL37855544410652BindingDB-show
CHEMBL37911420635525BindingDB-show
CHEMBL37928144410514BindingDB-show
CHEMBL37947820635235BindingDB-show
CHEMBL38004244413087BindingDB-show
CHEMBL38005820635527BindingDB-show
CHEMBL38007544410457BindingDB-show
CHEMBL38008244410660BindingDB-show
CHEMBL38110744410428BindingDB-show
CHEMBL38129620635405BindingDB-show
CHEMBL38136744410746BindingDB-show
CHEMBL38236211527400BindingDB-show
CHEMBL38312920635396BindingDB-show
CHEMBL38345544410456BindingDB-show
CHEMBL38376720635410BindingDB-show
CHEMBL38468020635262BindingDB-show
CHEMBL38666116086104BindingDB-show
CHEMBL39167944432424BindingDB-show
CHEMBL39188344432426BindingDB-show
CHEMBL39188410217158BindingDB-show
CHEMBL39193410151831BindingDB-show
CHEMBL39204810228329BindingDB-show
CHEMBL39899944432432BindingDB-show
CHEMBL40022844432440BindingDB-show
CHEMBL42523544410421BindingDB-show
CHEMBL42649944410667BindingDB-show
CHEMBL42668522170437BindingDB-show
CHEMBL42703344410424BindingDB-show
CHEMBL42925644432439BindingDB-show
CHEMBL4374959914277BindingDB-show
CHEMBL44004644410656BindingDB-show
CHEMBL44415144589018BindingDB-show
CHEMBL45063544589718BindingDB-show
CHEMBL45770544589045BindingDB-show
CHEMBL45770625190520BindingDB-show
CHEMBL45788625190510BindingDB-show
CHEMBL45860444589020BindingDB-show
CHEMBL45878744589021BindingDB-show
CHEMBL45879625190517BindingDB-show
CHEMBL45879744589047BindingDB-show
CHEMBL45879844589048BindingDB-show
CHEMBL46038944588579BindingDB-show
CHEMBL46082344588582BindingDB-show
CHEMBL46082425110758BindingDB-show
CHEMBL46102944588584BindingDB-show
CHEMBL46230125110760BindingDB-show
CHEMBL46251444588581BindingDB-show
CHEMBL47781724766030BindingDB-show
CHEMBL48318144588846BindingDB-show
CHEMBL48339744588765BindingDB-show
CHEMBL48340325110796BindingDB-show
CHEMBL48358144588965BindingDB-show
CHEMBL48360244588793BindingDB-show
CHEMBL48376344588969BindingDB-show
CHEMBL48376444588970BindingDB-show
CHEMBL48439544588917BindingDB-show
CHEMBL48454644588879BindingDB-show
CHEMBL48476644588966BindingDB-show
CHEMBL48476744588967BindingDB-show
CHEMBL48493444588968BindingDB-show
CHEMBL48494044588791BindingDB-show
CHEMBL48494144588792BindingDB-show
CHEMBL48494544588994BindingDB-show
CHEMBL48503044588997BindingDB-show
CHEMBL48503125191024BindingDB-show
CHEMBL48520144589015BindingDB-show
CHEMBL48520225190503BindingDB-show
CHEMBL48520325110759BindingDB-show
CHEMBL48520644589016BindingDB-show
CHEMBL48523244588738BindingDB-show
CHEMBL48523344588739BindingDB-show
CHEMBL48537844589019BindingDB-show
CHEMBL48539044588847BindingDB-show
CHEMBL48539944588880BindingDB-show
CHEMBL48540244588740BindingDB-show
CHEMBL48555544588845BindingDB-show
CHEMBL48556423628269BindingDB-show
CHEMBL48556544588719BindingDB-show
CHEMBL48558444588606BindingDB-show
CHEMBL48559144588607BindingDB-show
CHEMBL48560744588766BindingDB-show
CHEMBL48562644588995BindingDB-show
CHEMBL48633444589757BindingDB-show
CHEMBL48675544589832BindingDB-show
CHEMBL48675725110600BindingDB-show
CHEMBL48735744589754BindingDB-show
CHEMBL48735844589755BindingDB-show
CHEMBL48756344589756BindingDB-show
CHEMBL48796944589717BindingDB-show
CHEMBL48798244589640BindingDB-show
CHEMBL48798344589642BindingDB-show
CHEMBL48798744589677BindingDB-show
CHEMBL48817044589719BindingDB-show
CHEMBL48818644589678BindingDB-show
CHEMBL48818744589680BindingDB-show
CHEMBL48839844589793BindingDB-show
CHEMBL48839944589794BindingDB-show
CHEMBL48926644588946BindingDB-show
CHEMBL48946044588947BindingDB-show
CHEMBL49026944588996BindingDB-show
CHEMBL49087244588998BindingDB-show
CHEMBL49107644589017BindingDB-show
CHEMBL49275744573266BindingDB-show
CHEMBL49275844573267BindingDB-show
CHEMBL49293144573146BindingDB-show
CHEMBL49299044573469BindingDB-show
CHEMBL49300744573502BindingDB-show
CHEMBL49300844573503BindingDB-show
CHEMBL49310644573268BindingDB-show
CHEMBL49310744573269BindingDB-show
CHEMBL49316944219632BindingDB-show
CHEMBL49331844573306BindingDB-show
CHEMBL49331944573307BindingDB-show
CHEMBL49353744573377BindingDB-show
CHEMBL49392844573309BindingDB-show
CHEMBL49402744573504BindingDB-show
CHEMBL49413544573375BindingDB-show
CHEMBL49413644573376BindingDB-show
CHEMBL49422144219633BindingDB-show
CHEMBL49474344573546BindingDB-show
CHEMBL49499344573427BindingDB-show
CHEMBL49502644573425BindingDB-show
CHEMBL49518144573467BindingDB-show
CHEMBL49921944573374BindingDB-show
CHEMBL51601244589049BindingDB-show
CHEMBL51617344589046BindingDB-show
CHEMBL51695844588583BindingDB-show
CHEMBL51790144588580BindingDB-show
CHEMBL51893244589641BindingDB-show
CHEMBL51903344593710BindingDB-show
CHEMBL51908844589716BindingDB-show
CHEMBL51918344588916BindingDB-show
CHEMBL51934744588918BindingDB-show
CHEMBL51969844588741BindingDB-show
CHEMBL52031244588767BindingDB-show
CHEMBL52056544589679BindingDB-show
CHEMBL52072844589639BindingDB-show
CHEMBL52146844588794BindingDB-show
CHEMBL52148444588878BindingDB-show
CHEMBL52169544573424BindingDB-show
CHEMBL52208544588945BindingDB-show
CHEMBL52232844201333BindingDB-show
CHEMBL52268244573505BindingDB-show
CHEMBL52271144573468BindingDB-show
CHEMBL52284944573308BindingDB-show
CHEMBL52287144573426BindingDB-show
CHEMBL52363344588999BindingDB-show
CHEMBL52898944589795BindingDB-show
CHEMBL56892211723489BindingDB-show
CHEMBL57688723401001BindingDB-show
CHEMBL57698923400934BindingDB-show
CHEMBL57860110246246BindingDB-show
CHEMBL60408725057409BindingDB-show
CHIR-2589886808BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Kinome_248146224684BindingDB-show
Kinome_277644593713BindingDB-show
Kinome_277844588881BindingDB-show
Kinome_277944588915BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_71446886323BindingDB-show
L2G9549184BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
Pelitinib6445562BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine451705BindingDB-show
staurosporine44299148BindingDB-show
STAUROSPORINE44259DrugBank-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
Kinase EMT
T-cell-specific kinase
Tyrosine-protein kinase ITK/TSK
Tyrosine-protein kinase Lyk
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
BTK_HUMAN66.349.7
FYN_HUMAN43.927.5
YES_HUMAN43.327.4
LCK_HUMAN43.326.2
HCK_HUMAN42.227
SRC_RAT41.527.2
SRC_HUMAN41.327.2
CSK_HUMAN40.125.8
SRC_RSVSE39.126
ZAP70_HUMAN3824
PAK1_CAEEL3621.1
KSYK_HUMAN35.822
Q9Y6B5_HUMAN33.220
AMYP_PIG31.120.2
RAF1_MOUSE3117.6
KPCE_HUMAN30.817.2
FGFR4_HUMAN30.819.7
RAF1_RAT30.817.6
Q99052_MOUSE30.519.4
LT_SV4030.514.2
KPCB_HUMAN30.517.5
AL4A1_HUMAN30.416.3
PCKGC_CHICK30.419.6
SYT_SHIFL30.418.3
ACES_TORCA30.316.3
KPCB_BOVIN30.117.4
KPCD_MOUSE30.116.5
AMY_BACSU3017.9
OCTC_MOUSE3018.1
KPCB_RAT3017.3
Protein-Protein Interactions: