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Target Details

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Name:CD220
Uniprot name:INSR_HUMAN
Accession Numbers:P06213 Q17RW0 Q59H98 Q9UCB7 Q9UCB8 Q9UCB9
EC-Number:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1GAG 1I44 1IR3 1IRK 1P14 1RQQ 2AUH 2B4S 2DTG 2HR7 2Z8C 3BU3 3BU5 3BU6 3EKK 3EKN 3ETA
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
5-(2,4-dichlorobenzylidene)-1,3-thiazolidine-2,4-dione1230091BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 135328115BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 325328134BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 335328135BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 475328149BindingDB-show
7MP10062694BindingDB-show
ABT-86911485656BindingDB-show
AC1NS3TB5328117BindingDB-show
AG 2135328803BindingDB-show
AG-690/344700551204889BindingDB-show
AG-690/346530121205040BindingDB-show
AG-690/361650491731052BindingDB-show
AG-690/366300511205672BindingDB-show
AG-690/370991071206018BindingDB-show
AG-690/401247671206261BindingDB-show
AM-879/126330101774817BindingDB-show
Ambcb919993030851656BindingDB-show
AMG 70611667893BindingDB-show
AN-988/417198741231530BindingDB-show
AST-48711409972BindingDB-show
BAS 002535681206240BindingDB-show
BAS 002536111206256BindingDB-show
BAS 002536131225146BindingDB-show
BAS 007893531565908BindingDB-show
BAS 027604855349975BindingDB-show
Bio2_0004136610353BindingDB-show
BMS-53692410390396BindingDB-show
Canertinib156414BindingDB-show
Cannabiscetin5281672BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:30525144348997BindingDB-show
CHEBI:64749644358270BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL1040749796455BindingDB-show
CHEMBL107562815949620BindingDB-show
CHEMBL107619315948947BindingDB-show
CHEMBL107619446879439BindingDB-show
CHEMBL107619546879440BindingDB-show
CHEMBL107619646879441BindingDB-show
CHEMBL107619746879442BindingDB-show
CHEMBL107619846879443BindingDB-show
CHEMBL107619946220496BindingDB-show
CHEMBL107620046879444BindingDB-show
CHEMBL107620146879445BindingDB-show
CHEMBL107620246879446BindingDB-show
CHEMBL107620346879448BindingDB-show
CHEMBL107643215948949BindingDB-show
CHEMBL107643315949524BindingDB-show
CHEMBL107643615949523BindingDB-show
CHEMBL107643715949048BindingDB-show
CHEMBL107646546880067BindingDB-show
CHEMBL107646646880068BindingDB-show
CHEMBL107646815949975BindingDB-show
CHEMBL107646946880069BindingDB-show
CHEMBL107647015950141BindingDB-show
CHEMBL107647146880070BindingDB-show
CHEMBL107647246880071BindingDB-show
CHEMBL107647346880072BindingDB-show
CHEMBL107647415949890BindingDB-show
CHEMBL107647546880073BindingDB-show
CHEMBL107647615949888BindingDB-show
CHEMBL107647715949974BindingDB-show
CHEMBL107647815949976BindingDB-show
CHEMBL107648046880098BindingDB-show
CHEMBL107653346880214BindingDB-show
CHEMBL107729111580208BindingDB-show
CHEMBL107942215949522BindingDB-show
CHEMBL107942446879438BindingDB-show
CHEMBL107994515950224BindingDB-show
CHEMBL107994646879907BindingDB-show
CHEMBL108029446879447BindingDB-show
CHEMBL108029915949521BindingDB-show
CHEMBL108093046880216BindingDB-show
CHEMBL108109046880213BindingDB-show
CHEMBL108119811755812BindingDB-show
CHEMBL108143646880215BindingDB-show
CHEMBL108282946889887BindingDB-show
CHEMBL108352746881851BindingDB-show
CHEMBL108433746889911BindingDB-show
CHEMBL108551124762205BindingDB-show
CHEMBL108673115949617BindingDB-show
CHEMBL108686015949619BindingDB-show
CHEMBL108700246880099BindingDB-show
CHEMBL108712746880100BindingDB-show
CHEMBL108712846880101BindingDB-show
CHEMBL108751315949621BindingDB-show
CHEMBL108752415950311BindingDB-show
CHEMBL108763646880066BindingDB-show
CHEMBL108763815949889BindingDB-show
CHEMBL108764946880135BindingDB-show
CHEMBL108802746880133BindingDB-show
CHEMBL108802846880134BindingDB-show
CHEMBL108815315949618BindingDB-show
CHEMBL108842915949525BindingDB-show
CHEMBL109440824993189BindingDB-show
CHEMBL109587316223008BindingDB-show
CHEMBL116417746906712BindingDB-show
CHEMBL116426246906713BindingDB-show
CHEMBL116426446906788BindingDB-show
CHEMBL116435346871726BindingDB-show
CHEMBL116445346906898BindingDB-show
CHEMBL116445744250389BindingDB-show
CHEMBL116550746906899BindingDB-show
CHEMBL11689310783460BindingDB-show
CHEMBL11690710806447BindingDB-show
CHEMBL1172069949424BindingDB-show
CHEMBL11744010689056BindingDB-show
CHEMBL1200779797370BindingDB-show
CHEMBL124067643743432BindingDB-show
CHEMBL124067743680262BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL124082928491869BindingDB-show
CHEMBL124166952945447BindingDB-show
CHEMBL124167052945448BindingDB-show
CHEMBL124176452946684BindingDB-show
CHEMBL125400715949613BindingDB-show
CHEMBL125891311847343BindingDB-show
CHEMBL127023024809764BindingDB-show
CHEMBL128816049839481BindingDB-show
CHEMBL129007250908681BindingDB-show
CHEMBL15089410275001BindingDB-show
CHEMBL1758629951708BindingDB-show
CHEMBL17601910318355BindingDB-show
CHEMBL17607810452258BindingDB-show
CHEMBL17729810249989BindingDB-show
CHEMBL19765211553173BindingDB-show
CHEMBL19839911605000BindingDB-show
CHEMBL19929811532796BindingDB-show
CHEMBL19972311669784BindingDB-show
CHEMBL19988611576375BindingDB-show
CHEMBL20127711568821BindingDB-show
CHEMBL20151111530963BindingDB-show
CHEMBL20155311719817BindingDB-show
CHEMBL20163811691146BindingDB-show
CHEMBL20163911655878BindingDB-show
CHEMBL20283011576099BindingDB-show
CHEMBL20283111569457BindingDB-show
CHEMBL20335411590126BindingDB-show
CHEMBL20914811467730BindingDB-show
CHEMBL23757024180608BindingDB-show
CHEMBL25388121081523BindingDB-show
CHEMBL25801544447890BindingDB-show
CHEMBL2819579869943BindingDB-show
CHEMBL3273009927943BindingDB-show
CHEMBL33113710643731BindingDB-show
CHEMBL37080011604739BindingDB-show
CHEMBL38173811662893BindingDB-show
CHEMBL39860611248502BindingDB-show
CHEMBL40189644447895BindingDB-show
CHEMBL42718811705264BindingDB-show
CHEMBL43273810738332BindingDB-show
CHEMBL43297110736056BindingDB-show
CHEMBL43650911604436BindingDB-show
CHEMBL44390644565016BindingDB-show
CHEMBL44710715949712BindingDB-show
CHEMBL44731725178328BindingDB-show
CHEMBL44892944571820BindingDB-show
CHEMBL45770544589045BindingDB-show
CHEMBL45770625190520BindingDB-show
CHEMBL45788625190510BindingDB-show
CHEMBL45879625190517BindingDB-show
CHEMBL45988644564751BindingDB-show
CHEMBL46038944588579BindingDB-show
CHEMBL46082425110758BindingDB-show
CHEMBL46110944564787BindingDB-show
CHEMBL46111044564788BindingDB-show
CHEMBL46199144564747BindingDB-show
CHEMBL46216044564749BindingDB-show
CHEMBL46216144564750BindingDB-show
CHEMBL46216244564790BindingDB-show
CHEMBL46230125110760BindingDB-show
CHEMBL46233844564791BindingDB-show
CHEMBL46401444564705BindingDB-show
CHEMBL46421044564706BindingDB-show
CHEMBL47294644564820BindingDB-show
CHEMBL47325015949887BindingDB-show
CHEMBL47335144564953BindingDB-show
CHEMBL47335444564911BindingDB-show
CHEMBL47355344156917BindingDB-show
CHEMBL47355616042971BindingDB-show
CHEMBL47355744564910BindingDB-show
CHEMBL47376144564955BindingDB-show
CHEMBL47434644564860BindingDB-show
CHEMBL47434744564861BindingDB-show
CHEMBL47454344564862BindingDB-show
CHEMBL47454444564863BindingDB-show
CHEMBL47535144564817BindingDB-show
CHEMBL47535244564819BindingDB-show
CHEMBL48318144588846BindingDB-show
CHEMBL48339744588765BindingDB-show
CHEMBL48340325110796BindingDB-show
CHEMBL48360244588793BindingDB-show
CHEMBL48494044588791BindingDB-show
CHEMBL48520225190503BindingDB-show
CHEMBL48520325110759BindingDB-show
CHEMBL48520644589016BindingDB-show
CHEMBL48523244588738BindingDB-show
CHEMBL48523344588739BindingDB-show
CHEMBL48540244588740BindingDB-show
CHEMBL48555544588845BindingDB-show
CHEMBL48556423628269BindingDB-show
CHEMBL48556544588719BindingDB-show
CHEMBL48560744588766BindingDB-show
CHEMBL48827125178540BindingDB-show
CHEMBL48864624894992BindingDB-show
CHEMBL48881124894997BindingDB-show
CHEMBL48884025065806BindingDB-show
CHEMBL48908325178539BindingDB-show
CHEMBL49055544565015BindingDB-show
CHEMBL49167744565069BindingDB-show
CHEMBL49168644565013BindingDB-show
CHEMBL49275744573266BindingDB-show
CHEMBL49275844573267BindingDB-show
CHEMBL49293144573146BindingDB-show
CHEMBL49299044573469BindingDB-show
CHEMBL49300744573502BindingDB-show
CHEMBL49300844573503BindingDB-show
CHEMBL49310644573268BindingDB-show
CHEMBL49310744573269BindingDB-show
CHEMBL49331844573306BindingDB-show
CHEMBL49331944573307BindingDB-show
CHEMBL49353744573377BindingDB-show
CHEMBL49392844573309BindingDB-show
CHEMBL49402744573504BindingDB-show
CHEMBL49413544573375BindingDB-show
CHEMBL49413644573376BindingDB-show
CHEMBL49474344573546BindingDB-show
CHEMBL49499344573427BindingDB-show
CHEMBL49502644573425BindingDB-show
CHEMBL49518144573467BindingDB-show
CHEMBL4979499890085BindingDB-show
CHEMBL49921944573374BindingDB-show
CHEMBL50454742625986BindingDB-show
CHEMBL50724944591740BindingDB-show
CHEMBL50771425124150BindingDB-show
CHEMBL50943524894883BindingDB-show
CHEMBL51293344564748BindingDB-show
CHEMBL51401644564864BindingDB-show
CHEMBL51487325210970BindingDB-show
CHEMBL51492944564821BindingDB-show
CHEMBL51494144564954BindingDB-show
CHEMBL51494244156909BindingDB-show
CHEMBL51551944581271BindingDB-show
CHEMBL51559844564818BindingDB-show
CHEMBL51880344564789BindingDB-show
CHEMBL51969844588741BindingDB-show
CHEMBL52031244588767BindingDB-show
CHEMBL52049744582794BindingDB-show
CHEMBL52146844588794BindingDB-show
CHEMBL52169544573424BindingDB-show
CHEMBL52232844201333BindingDB-show
CHEMBL52268244573505BindingDB-show
CHEMBL52271144573468BindingDB-show
CHEMBL52278544565014BindingDB-show
CHEMBL52284944573308BindingDB-show
CHEMBL52287144573426BindingDB-show
CHEMBL52520323507191BindingDB-show
CHEMBL52966324894117BindingDB-show
CHEMBL54982645270590BindingDB-show
CHEMBL55126416659012BindingDB-show
CHEMBL55157045272300BindingDB-show
CHEMBL55190644219665BindingDB-show
CHEMBL55659645268038BindingDB-show
CHEMBL55749144219667BindingDB-show
CHEMBL55870845273507BindingDB-show
CHEMBL56024545267171BindingDB-show
CHEMBL56044645267177BindingDB-show
CHEMBL56272445271734BindingDB-show
CHEMBL56294344219666BindingDB-show
CHEMBL56308045273165BindingDB-show
CHEMBL56325745273175BindingDB-show
CHEMBL56355545272290BindingDB-show
CHEMBL56436545267176BindingDB-show
CHEMBL56441745272610BindingDB-show
CHEMBL56467945268916BindingDB-show
CHEMBL56892211723489BindingDB-show
CHEMBL57458845482700BindingDB-show
CHEMBL57461345482750BindingDB-show
CHEMBL57688723401001BindingDB-show
CHEMBL57698923400934BindingDB-show
CHEMBL57860110246246BindingDB-show
CHEMBL5895301205024BindingDB-show
CHEMBL59076945379062BindingDB-show
CHEMBL59102146229161BindingDB-show
CHEMBL59189645379200BindingDB-show
CHEMBL59659845379205BindingDB-show
CHEMBL59680745379347BindingDB-show
CHEMBL59680845379490BindingDB-show
CHEMBL59698845379714BindingDB-show
CHEMBL59700545379060BindingDB-show
CHEMBL59719145379611BindingDB-show
CHEMBL59720745379202BindingDB-show
CHEMBL59739345379712BindingDB-show
CHEMBL59758645379493BindingDB-show
CHEMBL59759645379713BindingDB-show
CHEMBL59759745379715BindingDB-show
CHEMBL59775446233287BindingDB-show
CHEMBL59800045379607BindingDB-show
CHEMBL59802445379345BindingDB-show
CHEMBL59802545379346BindingDB-show
CHEMBL59820145379608BindingDB-show
CHEMBL59841845379610BindingDB-show
CHEMBL59843145379816BindingDB-show
CHEMBL59843445379058BindingDB-show
CHEMBL59843545379201BindingDB-show
CHEMBL59863345379813BindingDB-show
CHEMBL59883745379814BindingDB-show
CHEMBL59902745379605BindingDB-show
CHEMBL59905545379341BindingDB-show
CHEMBL59905645379343BindingDB-show
CHEMBL59922445139989BindingDB-show
CHEMBL59924745379063BindingDB-show
CHEMBL59924845379064BindingDB-show
CHEMBL59942845139991BindingDB-show
CHEMBL59944645379811BindingDB-show
CHEMBL59966645379204BindingDB-show
CHEMBL59984445379496BindingDB-show
CHEMBL60079546232443BindingDB-show
CHEMBL60204345379717BindingDB-show
CHEMBL60247146232555BindingDB-show
CHEMBL60247246232556BindingDB-show
CHEMBL60325545379344BindingDB-show
CHEMBL60325945379199BindingDB-show
CHEMBL60346316730105BindingDB-show
CHEMBL60348145379203BindingDB-show
CHEMBL60348246228648BindingDB-show
CHEMBL60354545379606BindingDB-show
CHEMBL60454545379495BindingDB-show
CHEMBL60471210429593BindingDB-show
CHEMBL60491245379711BindingDB-show
CHEMBL60511845379716BindingDB-show
CHEMBL60532445379491BindingDB-show
CHEMBL60584145379492BindingDB-show
CHEMBL60611945379340BindingDB-show
CHEMBL60618545379815BindingDB-show
CHEMBL60625545379812BindingDB-show
CHEMBL60639545379609BindingDB-show
CHEMBL60641045379494BindingDB-show
CHEMBL60842745379061BindingDB-show
CHEMBL61051245379342BindingDB-show
CHEMBL7518810602350BindingDB-show
CHIR-26511656518BindingDB-show
CID 1151838911518389BindingDB-show
CID 99267919818231BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Demethylasterriquinone B13013166BindingDB-show
Dimethylguanylguanidine4091SuperTargetPMID 015135305show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GSK1904529A25124816BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Intedanib9809715BindingDB-show
irtk activator9819548BindingDB-show
Kenpaullone3820BindingDB-show
Kinome_277644593713BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_71446886323BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
nchembio.90-comp111715767BindingDB-show
NVP-AEW54145270897BindingDB-show
NVP-TAE68416038120BindingDB-show
OH-Name-PA129317BindingDB-show
Pazopanib10113978BindingDB-show
PD0898285328112BindingDB-show
PD089828 analog 45329111BindingDB-show
PD1626285328125BindingDB-show
PDSP1_0006835328127BindingDB-show
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER91532DrugBank-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Purvalanol A456214BindingDB-show
pyrido(2,3-d)pyrimidine1401BindingDB-show
Pyrrolo[2,3-d]pyrimidine 16539952BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1363_Selleck11317348BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
ST0888051218955BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
STK1556431205381BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
ZINC000169785329009BindingDB-show
ZINC009738101204893BindingDB-show
ZINC009758271206252BindingDB-show
ZINC009758281206254BindingDB-show
ZINC009758391206264BindingDB-show
ZINC009758651206279BindingDB-show
ZINC010050521227452BindingDB-show
ZINC010129801232262BindingDB-show
ZINC010139081232814BindingDB-show
ZINC010208551237187BindingDB-show
ZINC020684571731078BindingDB-show
ZINC031174115753500BindingDB-show
ZINC057200826155669BindingDB-show
Synonyms:
CD220
Insulin receptor
IR
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
IGF1R_HUMAN72.456.9
Q86WY9_HUMAN53.353.3
VGFR3_HUMAN32.819.8
EGFR_MOUSE31.721.2
ALK_HUMAN31.720.5
MET_HUMAN31.518.4
EGFR_HUMAN31.420.9
ERBB4_HUMAN30.921
ERBB2_HUMAN30.820.7
EGFR_DROME30.519.2
VGFR2_HUMAN30.118.8
VGFR1_HUMAN29.818.1
PK3CA_MOUSE29.216.9
DGKD_HUMAN29.217
Q9ZWQ6_ADICA29.217.2
PK3CA_HUMAN2916.7
DPOL_HCMVA28.617.3
SYIC_HUMAN28.515.8
EPHB1_HUMAN28.117.3
JAK2_RAT28.116.1
EPHB2_MOUSE27.917.2
JAK2_HUMAN27.916.1
TETX_CLOTE27.816
ACLY_RAT27.816.3
GCSP_HUMAN27.316.6
ADCYA_RABIT27.315.6
Q59FL8_HUMAN27.317.9
TOP2_CRIFA27.215.4
ITA11_HUMAN27.216
TYRO3_HUMAN26.816.9
Protein-Protein Interactions: