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Target Details

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Name:IMP dehydrogenase 2
Uniprot name:IMDH2_HUMAN
Accession Numbers:P12268 Q6LEF3
EC-Number:1.1.1.205
Organism:Homo sapiens
Human
PDB IDs:1B3O 1NF7 1NFB
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1(3H)-one46839320BindingDB-show
1-Methyl-1H-indole-3-carbaldehyde87894BindingDB-show
1-Methyl-1H-indole-3-carbonitrile2307681BindingDB-show
3-(3-furyl)-1H-indole10607518BindingDB-show
3-Indolecarbonitrile230282BindingDB-show
6-Aminoisoquinoline588991BindingDB-show
6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE5287975DrugBank-show
AC1LABSF510912BindingDB-show
AC1LABSI510913BindingDB-show
AC1LABSL510914BindingDB-show
AC1LABSO510915BindingDB-show
AC1LABSR510916BindingDB-show
AC1LABSU510917BindingDB-show
AC1LABSX510918BindingDB-show
AC1LABT0510919BindingDB-show
AC1LABT3510920BindingDB-show
AC1LABT6510921BindingDB-show
AC1LABTC510923BindingDB-show
AC1LABTF510924BindingDB-show
AC1LABTI510925BindingDB-show
AC1LABTL510926BindingDB-show
AC1LABTO510927BindingDB-show
AC1LABTR510928BindingDB-show
AC1LABTU510929BindingDB-show
AC1LABTX510930BindingDB-show
AC1LABU6510933BindingDB-show
AC1LABU9510934BindingDB-show
AC1LABUC510935BindingDB-show
AC1LAY04497770BindingDB-show
AC1LAY06497771BindingDB-show
AC1LAY08497772BindingDB-show
AC1LAY0A497773BindingDB-show
AC1LAY0C497774BindingDB-show
AC1LAY0E497775BindingDB-show
AC1LAY0G497776BindingDB-show
AC1LAY0I497777BindingDB-show
AC1LAY0Q497781BindingDB-show
AC1LAY0S497782BindingDB-show
AC1LAY0U497783BindingDB-show
AC1LAY0W497784BindingDB-show
AC1LAY0Y497785BindingDB-show
AC1LAY10497786BindingDB-show
AC1LAY12497787BindingDB-show
AC1LAY14497788BindingDB-show
AC1LAY18497790BindingDB-show
AC1LAY1A497791BindingDB-show
AC1LDOOT671222BindingDB-show
Acridone-Based Inhibitor, 323648230BindingDB-show
Acridone-Based Inhibitor, 4a16748021BindingDB-show
Acridone-Based Inhibitor, 4b16748525BindingDB-show
Acridone-Based Inhibitor, 4c16748022BindingDB-show
Acridone-Based Inhibitor, 4d16748526BindingDB-show
Acridone-Based Inhibitor, 4e16748267BindingDB-show
Acridone-Based Inhibitor, 4f16748142BindingDB-show
Acridone-Based Inhibitor, 4g16748527BindingDB-show
Acridone-Based Inhibitor, 4h16748143BindingDB-show
Acridone-Based Inhibitor, 4i16748528BindingDB-show
Acridone-Based Inhibitor, 4j16748144BindingDB-show
Acridone-Based Inhibitor, 4k16748529BindingDB-show
Acridone-Based Inhibitor, 4l16748145BindingDB-show
Acridone-Based Inhibitor, 4n9912093BindingDB-show
Acridone-Based Inhibitor, 4o16748274BindingDB-show
Acridone-Based Inhibitor, 4p16748745BindingDB-show
Acridone-Based Inhibitor, 8a16748634BindingDB-show
Acridone-Based Inhibitor, 8b16748017BindingDB-show
Acridone-Based Inhibitor, 8c16748635BindingDB-show
Acridone-Based Inhibitor, 8d16748018BindingDB-show
Acridone-Based Inhibitor, 8e16748636BindingDB-show
Acridone-Based Inhibitor, 8f16748019BindingDB-show
Acridone-Based Inhibitor, 8g16748020BindingDB-show
Acridone-Based Inhibitor, 8h16748637BindingDB-show
AIDS0888976479891BindingDB-show
AIDS155258497792BindingDB-show
BMS-5664199913339BindingDB-show
C2-MPAlc3006288BindingDB-show
C2-MYCOPHENOLIC ADENINE DINUCLEOTIDE477579BindingDB-show
C6-MPAIC6479888BindingDB-show
CHEBI:11097744268125BindingDB-show
CHEBI:11108944268183BindingDB-show
CHEBI:11110044268188BindingDB-show
CHEBI:13128144459439BindingDB-show
CHEBI:16969544291981BindingDB-show
CHEBI:16969644291982BindingDB-show
CHEBI:16969744291983BindingDB-show
CHEBI:16982644292043BindingDB-show
CHEBI:16982744292044BindingDB-show
CHEBI:23576244318914BindingDB-show
CHEBI:23576344318915BindingDB-show
CHEBI:23606144319033BindingDB-show
CHEBI:32572544357157BindingDB-show
CHEBI:32638244357491BindingDB-show
CHEBI:36890344375134BindingDB-show
CHEBI:36893844375153BindingDB-show
CHEBI:36897644375178BindingDB-show
CHEBI:36941044375416BindingDB-show
CHEBI:36941244375418BindingDB-show
CHEBI:36956844375518BindingDB-show
CHEBI:37699644378929BindingDB-show
CHEBI:37703544378949BindingDB-show
CHEBI:37703844378950BindingDB-show
CHEBI:37778344379261BindingDB-show
CHEBI:37778444379262BindingDB-show
CHEBI:37784644379286BindingDB-show
CHEBI:37788244379305BindingDB-show
CHEBI:37788444379307BindingDB-show
CHEMBL10020522058546BindingDB-show
CHEMBL10040322058554BindingDB-show
CHEMBL10092922058516BindingDB-show
CHEMBL10127022093099BindingDB-show
CHEMBL10146344330773BindingDB-show
CHEMBL10182210131741BindingDB-show
CHEMBL10194144330750BindingDB-show
CHEMBL10198410323922BindingDB-show
CHEMBL10405122459748BindingDB-show
CHEMBL1042409797707BindingDB-show
CHEMBL10428222459738BindingDB-show
CHEMBL10431344336201BindingDB-show
CHEMBL10453522459627BindingDB-show
CHEMBL10471022459693BindingDB-show
CHEMBL10473922459727BindingDB-show
CHEMBL10733722459610BindingDB-show
CHEMBL10931210434905BindingDB-show
CHEMBL10932444340450BindingDB-show
CHEMBL10933544340666BindingDB-show
CHEMBL11000544340674BindingDB-show
CHEMBL11240544340724BindingDB-show
CHEMBL11244444340423BindingDB-show
CHEMBL11296744340410BindingDB-show
CHEMBL11299344340409BindingDB-show
CHEMBL11357244340431BindingDB-show
CHEMBL11442610688491BindingDB-show
CHEMBL11606144340424BindingDB-show
CHEMBL11620844345267BindingDB-show
CHEMBL11659644345137BindingDB-show
CHEMBL117084846839190BindingDB-show
CHEMBL117085046839192BindingDB-show
CHEMBL11740818184806BindingDB-show
CHEMBL11838444345310BindingDB-show
CHEMBL11871444345136BindingDB-show
CHEMBL11898844345138BindingDB-show
CHEMBL11940810345767BindingDB-show
CHEMBL13164110686776BindingDB-show
CHEMBL13169610732226BindingDB-show
CHEMBL13179310851956BindingDB-show
CHEMBL13185610495605BindingDB-show
CHEMBL13207010381198BindingDB-show
CHEMBL13218110711760BindingDB-show
CHEMBL13225810782926BindingDB-show
CHEMBL13235510758796BindingDB-show
CHEMBL13240410832148BindingDB-show
CHEMBL13241310495354BindingDB-show
CHEMBL13241710682843BindingDB-show
CHEMBL13242810637391BindingDB-show
CHEMBL13267410757447BindingDB-show
CHEMBL13272910709494BindingDB-show
CHEMBL13284710593915BindingDB-show
CHEMBL13289210735580BindingDB-show
CHEMBL13353810756343BindingDB-show
CHEMBL13371810519658BindingDB-show
CHEMBL13382610515627BindingDB-show
CHEMBL13389910826397BindingDB-show
CHEMBL13395410804648BindingDB-show
CHEMBL13395544355017BindingDB-show
CHEMBL13397210805499BindingDB-show
CHEMBL13397410544613BindingDB-show
CHEMBL13401144355016BindingDB-show
CHEMBL13405210710928BindingDB-show
CHEMBL13413210687933BindingDB-show
CHEMBL13415610569189BindingDB-show
CHEMBL13415710759638BindingDB-show
CHEMBL13420610519938BindingDB-show
CHEMBL13426510803200BindingDB-show
CHEMBL13436210852317BindingDB-show
CHEMBL13445810759053BindingDB-show
CHEMBL13466510662964BindingDB-show
CHEMBL13495310518087BindingDB-show
CHEMBL13495410828540BindingDB-show
CHEMBL13498844354983BindingDB-show
CHEMBL13505510616470BindingDB-show
CHEMBL13505610709767BindingDB-show
CHEMBL13512344354730BindingDB-show
CHEMBL13515310787380BindingDB-show
CHEMBL13515410497453BindingDB-show
CHEMBL13524810709184BindingDB-show
CHEMBL13541110496064BindingDB-show
CHEMBL13574010663129BindingDB-show
CHEMBL13578810735599BindingDB-show
CHEMBL14963822349495BindingDB-show
CHEMBL14969910136663BindingDB-show
CHEMBL14975544367690BindingDB-show
CHEMBL1504879856426BindingDB-show
CHEMBL15063110135675BindingDB-show
CHEMBL15072810131739BindingDB-show
CHEMBL15077744367538BindingDB-show
CHEMBL15106044367703BindingDB-show
CHEMBL15111222349571BindingDB-show
CHEMBL15122044367255BindingDB-show
CHEMBL15291044367615BindingDB-show
CHEMBL15293144367733BindingDB-show
CHEMBL15295910315709BindingDB-show
CHEMBL15297844367731BindingDB-show
CHEMBL1529889858793BindingDB-show
CHEMBL15301444367614BindingDB-show
CHEMBL15303210131333BindingDB-show
CHEMBL15311810273163BindingDB-show
CHEMBL15317544367718BindingDB-show
CHEMBL15318744367526BindingDB-show
CHEMBL1532239923286BindingDB-show
CHEMBL15324110200804BindingDB-show
CHEMBL15324710270744BindingDB-show
CHEMBL1533879966370BindingDB-show
CHEMBL15338910180910BindingDB-show
CHEMBL15341110225421BindingDB-show
CHEMBL15342944367420BindingDB-show
CHEMBL15348110276405BindingDB-show
CHEMBL15351144367248BindingDB-show
CHEMBL15351610159708BindingDB-show
CHEMBL15359510117522BindingDB-show
CHEMBL15370210221809BindingDB-show
CHEMBL15371544367590BindingDB-show
CHEMBL15375944367546BindingDB-show
CHEMBL15377144367512BindingDB-show
CHEMBL15377344367719BindingDB-show
CHEMBL15379444367730BindingDB-show
CHEMBL1547529947722BindingDB-show
CHEMBL15486710164678BindingDB-show
CHEMBL15561644367639BindingDB-show
CHEMBL15561710182966BindingDB-show
CHEMBL16278211069304BindingDB-show
CHEMBL17852044390811BindingDB-show
CHEMBL17923010309152BindingDB-show
CHEMBL17923144390765BindingDB-show
CHEMBL18000744390718BindingDB-show
CHEMBL18008844390721BindingDB-show
CHEMBL18031010172305BindingDB-show
CHEMBL18066344390711BindingDB-show
CHEMBL18213911440390BindingDB-show
CHEMBL18224244390777BindingDB-show
CHEMBL19691244405578BindingDB-show
CHEMBL19716344405453BindingDB-show
CHEMBL19753244405581BindingDB-show
CHEMBL19754644405446BindingDB-show
CHEMBL19852444405539BindingDB-show
CHEMBL19852644405476BindingDB-show
CHEMBL19853644405423BindingDB-show
CHEMBL19872944405475BindingDB-show
CHEMBL1987919976927BindingDB-show
CHEMBL19889744405441BindingDB-show
CHEMBL19907544405472BindingDB-show
CHEMBL19912844405429BindingDB-show
CHEMBL20219011670037BindingDB-show
CHEMBL20505144410608BindingDB-show
CHEMBL20521844410473BindingDB-show
CHEMBL20523644410644BindingDB-show
CHEMBL20532844410465BindingDB-show
CHEMBL20625744410796BindingDB-show
CHEMBL20647544410875BindingDB-show
CHEMBL20688611962096BindingDB-show
CHEMBL20694544410732BindingDB-show
CHEMBL20726244410707BindingDB-show
CHEMBL20737544410800BindingDB-show
CHEMBL20750111962095BindingDB-show
CHEMBL20750244410708BindingDB-show
CHEMBL20761244410928BindingDB-show
CHEMBL20762144410733BindingDB-show
CHEMBL20773044410602BindingDB-show
CHEMBL20821944410601BindingDB-show
CHEMBL20826144410730BindingDB-show
CHEMBL20852444410594BindingDB-show
CHEMBL20874844412544BindingDB-show
CHEMBL20892116007061BindingDB-show
CHEMBL2090699842306BindingDB-show
CHEMBL20972311118869BindingDB-show
CHEMBL21051544412773BindingDB-show
CHEMBL21090944412648BindingDB-show
CHEMBL21091044412597BindingDB-show
CHEMBL21095744412573BindingDB-show
CHEMBL21102344412598BindingDB-show
CHEMBL21127344412713BindingDB-show
CHEMBL21217044412759BindingDB-show
CHEMBL21219944412793BindingDB-show
CHEMBL21225244415063BindingDB-show
CHEMBL21262044412632BindingDB-show
CHEMBL21531144415246BindingDB-show
CHEMBL2310822238495BindingDB-show
CHEMBL2312744458846BindingDB-show
CHEMBL23553323648225BindingDB-show
CHEMBL2359022238483BindingDB-show
CHEMBL237169907596BindingDB-show
CHEMBL23840323626089BindingDB-show
CHEMBL2384222238492BindingDB-show
CHEMBL238439883477BindingDB-show
CHEMBL23846124749070BindingDB-show
CHEMBL2388322238485BindingDB-show
CHEMBL23890524748985BindingDB-show
CHEMBL23910524749072BindingDB-show
CHEMBL240929901690BindingDB-show
CHEMBL24696944440695BindingDB-show
CHEMBL2473710338010BindingDB-show
CHEMBL248409798978BindingDB-show
CHEMBL2486644275519BindingDB-show
CHEMBL2502722058491BindingDB-show
CHEMBL2508744275642BindingDB-show
CHEMBL251389797026BindingDB-show
CHEMBL2517944275688BindingDB-show
CHEMBL2568110177736BindingDB-show
CHEMBL2568910361468BindingDB-show
CHEMBL2602544276818BindingDB-show
CHEMBL2615544276698BindingDB-show
CHEMBL2625844276734BindingDB-show
CHEMBL2625922226545BindingDB-show
CHEMBL26410723648221BindingDB-show
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CHEMBL26587023648224BindingDB-show
CHEMBL2674144276869BindingDB-show
CHEMBL2701144276622BindingDB-show
CHEMBL2718944276798BindingDB-show
CHEMBL2732744275942BindingDB-show
CHEMBL2750420766964BindingDB-show
CHEMBL2752844276468BindingDB-show
CHEMBL2752944276469BindingDB-show
CHEMBL27718744458844BindingDB-show
CHEMBL27719022238496BindingDB-show
CHEMBL2775315040652BindingDB-show
CHEMBL277779819013BindingDB-show
CHEMBL2794844276467BindingDB-show
CHEMBL2798522558406BindingDB-show
CHEMBL27995720766928BindingDB-show
CHEMBL2801949884816BindingDB-show
CHEMBL28043122238488BindingDB-show
CHEMBL2807939838854BindingDB-show
CHEMBL28079920766951BindingDB-show
CHEMBL2808944275711BindingDB-show
CHEMBL28141544458898BindingDB-show
CHEMBL28163522238481BindingDB-show
CHEMBL28210244276709BindingDB-show
CHEMBL28269720766912BindingDB-show
CHEMBL28299744276803BindingDB-show
CHEMBL28301644276819BindingDB-show
CHEMBL28309622238480BindingDB-show
CHEMBL2832569949676BindingDB-show
CHEMBL28466244276963BindingDB-show
CHEMBL28511624999500BindingDB-show
CHEMBL28579444277008BindingDB-show
CHEMBL28581344276665BindingDB-show
CHEMBL29225822946293BindingDB-show
CHEMBL29316221343423BindingDB-show
CHEMBL29317544305192BindingDB-show
CHEMBL29364022459746BindingDB-show
CHEMBL2948044276804BindingDB-show
CHEMBL2992644276961BindingDB-show
CHEMBL2992744276962BindingDB-show
CHEMBL30222444304863BindingDB-show
CHEMBL30260944304884BindingDB-show
CHEMBL30262644305067BindingDB-show
CHEMBL30282744305013BindingDB-show
CHEMBL30304822459706BindingDB-show
CHEMBL30334144305048BindingDB-show
CHEMBL30360844308050BindingDB-show
CHEMBL30452122459765BindingDB-show
CHEMBL30505944308220BindingDB-show
CHEMBL30521410309428BindingDB-show
CHEMBL30537421343422BindingDB-show
CHEMBL30578610872836BindingDB-show
CHEMBL3075479906308BindingDB-show
CHEMBL30824122459661BindingDB-show
CHEMBL31433044329217BindingDB-show
CHEMBL31662244329328BindingDB-show
CHEMBL31694610269167BindingDB-show
CHEMBL31717444329815BindingDB-show
CHEMBL31749744330791BindingDB-show
CHEMBL31806622058500BindingDB-show
CHEMBL31841344330826BindingDB-show
CHEMBL31894144329800BindingDB-show
CHEMBL31988344329529BindingDB-show
CHEMBL32084744329366BindingDB-show
CHEMBL32158122058485BindingDB-show
CHEMBL32197222058540BindingDB-show
CHEMBL32478144340430BindingDB-show
CHEMBL32971444330807BindingDB-show
CHEMBL32995222058487BindingDB-show
CHEMBL33042822058499BindingDB-show
CHEMBL33366244345333BindingDB-show
CHEMBL33476010590744BindingDB-show
CHEMBL33521010685057BindingDB-show
CHEMBL33527210546858BindingDB-show
CHEMBL33544610709084BindingDB-show
CHEMBL33608410709955BindingDB-show
CHEMBL33641210643207BindingDB-show
CHEMBL33660110566972BindingDB-show
CHEMBL33724044354906BindingDB-show
CHEMBL33747110567307BindingDB-show
CHEMBL33770710826452BindingDB-show
CHEMBL34120610780300BindingDB-show
CHEMBL34599244367578BindingDB-show
CHEMBL3463969921906BindingDB-show
CHEMBL3477219880305BindingDB-show
CHEMBL34835911828231BindingDB-show
CHEMBL35623644367513BindingDB-show
CHEMBL35637144367244BindingDB-show
CHEMBL35688110113643BindingDB-show
CHEMBL3570699878581BindingDB-show
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CHEMBL35730910134808BindingDB-show
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CHEMBL35838344367217BindingDB-show
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CHEMBL6285122459707BindingDB-show
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CHEMBL6822122459608BindingDB-show
CHEMBL6952722459770BindingDB-show
CHEMBL6996244308105BindingDB-show
CHEMBL9538222058495BindingDB-show
CHEMBL9538322058533BindingDB-show
CHEMBL9541822058549BindingDB-show
CHEMBL9560112093480BindingDB-show
CHEMBL9562222058517BindingDB-show
CHEMBL9586522058523BindingDB-show
CHEMBL9596222058537BindingDB-show
CHEMBL9597622058536BindingDB-show
CHEMBL9709644329808BindingDB-show
CHEMBL9709722058535BindingDB-show
CHEMBL9804044329410BindingDB-show
CHEMBL9821544330738BindingDB-show
CHEMBL9822410358687BindingDB-show
CHEMBL9822544330808BindingDB-show
CHEMBL9826522093112BindingDB-show
CHEMBL9832244330828BindingDB-show
CHEMBL9839344330611BindingDB-show
CHEMBL9848844329801BindingDB-show
CHEMBL9850010269960BindingDB-show
CHEMBL987009946220BindingDB-show
CHEMBL9874044330827BindingDB-show
CHEMBL9890444330809BindingDB-show
CHEMBL9904444329556BindingDB-show
CHEMBL9923344329515BindingDB-show
CHEMBL9925822058530BindingDB-show
CHEMBL9927818467513BindingDB-show
CHEMBL9945112093481BindingDB-show
CHEMBL9957122058514BindingDB-show
CHEMBL9962510292172BindingDB-show
CHEMBL9987444329361BindingDB-show
CID 1012666810126668BindingDB-show
CID 1019445910194459BindingDB-show
Demethylmycophenolic acid25879063BindingDB-show
dihydrodiphosphopyridine nucleotide439153DrugBank-show
INDOLE-3-CARBOXALDEHYDE10256BindingDB-show
Mercaptopurine667490DrugBank-show
Merimepodib153241BindingDB-show
methylisobenzofuran-1(3H)-one46839191BindingDB-show
Methylnitroimidazolylmercaptopurine2265DrugBank-show
MPA-OMe6478685BindingDB-show
Mycophenolate mofetil5281078DrugBank-show
Mycophenolsaeure446541BindingDB-show
Mycophenolsaeure446541DrugBank-show
Mycophenolsaeure446541PROMISCUOUS2 PMIDsshow
Mycophenolsaeure446541SuperTarget-show
N-(4-chlorophenyl)-2-phenoxypropanamide3140491BindingDB-show
NAD449328DrugBank-show
NSC358285337960BindingDB-show
NSC617998356935BindingDB-show
Ribavirin monophosphate100252DrugBank-show
Ribavirin Triphosphate37542SuperTarget-show
rockout644354BindingDB-show
SELENAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE444451DrugBank-show
TCAD73680BindingDB-show
Theophyllaminium9433SuperTarget-show
Vidarabine6713976BindingDB-show
Synonyms:
IMP dehydrogenase 2
IMPD 2
IMPDH-II
Inosine-5'-monophosphate dehydrogenase 2
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
IMDH2_CRIGR99.498.8
IMDH1_HUMAN91.884
IMDH_STRPY53.736.3
IMDH_TRIFO48.230.9
Q7Z6H8_HUMAN33.620.3
OXLA_GLOBL33.216.6
GMPR2_HUMAN32.518.5
PADI2_HUMAN32.517.6
OXLA_GLOHA32.316.2
GLMU_ECOLI31.918.2
Q9EYQ2_9CLOT31.818.5
MCP2_SALTY31.818.2
SYY_THET231.716.5
GMPR1_HUMAN31.517.8
QCR1_HUMAN31.419.6
KPYM_HUMAN31.416.7
Q9X266_THEMA31.317.2
MPIP2_HUMAN31.115.8
GMPR1_RAT31.117.3
Q0QEN7_HUMAN31.117.3
KCRM_HUMAN31.117.3
TRXR2_RAT3119.1
AHPF_ECOLI3118.9
GABT_RAT30.917.7
UMPS_HUMAN30.816.7
DTX_COROM30.817.2
IDH_BACSU30.817.6
DXR_ECOLI30.715.7
Q8RBX6_THETN30.717.3
KPYM_RABIT30.616.2
Protein-Protein Interactions: