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Name:I kappa-B kinase epsilon
Uniprot name:IKKE_HUMAN
Accession Numbers:Q14164 Q3KR43 Q5JTS6
EC-Number:2.7.11.10
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2-amino-5-phenyl-benzamide11600944BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
ACHP10451420BindingDB-show
AMG 70611667893BindingDB-show
Amino-substituted diarylbenzamide, 8t16047973BindingDB-show
Amino-substituted diarylbenzamide, 8u16047852BindingDB-show
Amino-substituted diarylbenzamide, 8v16047740BindingDB-show
Amino-substituted diarylbenzamide, 8w16047851BindingDB-show
Amino-substituted diarylbenzamide, 8x16047853BindingDB-show
Amino-substituted diarylbenzamide, 8y16047743BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL125891311847343BindingDB-show
CHEMBL127023024809764BindingDB-show
CHEMBL21971125190913BindingDB-show
CHEMBL21984511546115BindingDB-show
CHEMBL21989925190912BindingDB-show
CHEMBL21999225190916BindingDB-show
CHEMBL22003225190914BindingDB-show
CHEMBL22009011584228BindingDB-show
CHEMBL22014511655827BindingDB-show
CHEMBL22106311709714BindingDB-show
CHEMBL22231811706720BindingDB-show
CHEMBL22342525190918BindingDB-show
CHEMBL23005516048084BindingDB-show
CHEMBL23027616047856BindingDB-show
CHEMBL23048815979284BindingDB-show
CHEMBL23059516048308BindingDB-show
CHEMBL23059716048194BindingDB-show
CHEMBL23080816048544BindingDB-show
CHEMBL23080916048414BindingDB-show
CHEMBL23081025190923BindingDB-show
CHEMBL23091116048415BindingDB-show
CHEMBL23110816047147BindingDB-show
CHEMBL23121116047150BindingDB-show
CHEMBL23152125190922BindingDB-show
CHEMBL23162316048303BindingDB-show
CHEMBL37375111626927BindingDB-show
CHEMBL37444025190915BindingDB-show
CHEMBL37511525190919BindingDB-show
CHEMBL37537925190917BindingDB-show
CHEMBL37578711625181BindingDB-show
CHEMBL37626211647864BindingDB-show
CHEMBL39700816048085BindingDB-show
CHEMBL39700916047968BindingDB-show
CHEMBL45419625190911BindingDB-show
CHIR-2589886808BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Flavopiridol hydrochloride5287969BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
O-substituted diarylbenzamide, 12c16047146BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-41224202429BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine451705BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
trihydroxidoarsenic545SuperTarget-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
I kappa-B kinase epsilon
IkBKE
IKK-E
IKK-epsilon
IKK-i
Inducible I kappa-B kinase
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
IKKB_HUMAN37.422.9
IKKA_HUMAN35.520.7
CHK1_USTMA32.819
SYTM_HUMAN32.719.1
Q8CHM5_MOUSE32.620.2
RIPK1_HUMAN32.218.5
Q9H4D1_HUMAN32.218.2
P85A_HUMAN31.119.3
HS90B_HUMAN30.816.5
TGM7_HUMAN30.418.9
PGKT_THEMA30.416
Q59GK6_HUMAN30.317.9
CAN1_RAT30.217.8
TERA_MOUSE30.114.7
KCC2A_RAT29.917.7
AIFM1_MOUSE29.916.7
K6PL_RAT29.817.3
DGKB_RAT29.716
ZBT16_HUMAN29.618.2
Q59GL9_HUMAN29.618.1
DCE1_MOUSE29.516.7
TRXR3_HUMAN29.516.5
DCE1_HUMAN29.315.9
AMO_PEA29.214.7
CLAT_RAT29.116.8
SGPL1_HUMAN29.117.3
PAOX_ARTGO28.916.5
SECA1_MYCTU28.816.6
CLPA_ECOLI28.817.3
ENPL_HUMAN28.716.1
Protein-Protein Interactions:
Uniprot nameSource
ZC3HF_HUMANPMID 17353931
VDAC3_HUMAN2 PMIDs
VDAC1_HUMAN3 PMIDs
VAMP3_HUMAN4 PMIDs
UGGG1_HUMAN5 PMIDs
UBIQ_HUMAN6 PMIDs
TTL12_HUMAN7 PMIDs
TSN_HUMAN8 PMIDs
TSNAX_HUMAN9 PMIDs
TR112_HUMAN10 PMIDs
TPD54_HUMAN11 PMIDs
TOM34_HUMAN12 PMIDs
TMM33_HUMAN13 PMIDs
TMED9_HUMAN14 PMIDs
TM111_HUMAN15 PMIDs
TIF1B_HUMAN16 PMIDs
THOP1_HUMAN17 PMIDs
TERA_HUMAN18 PMIDs
TERA_HUMAN19 PMIDs
TCTP_HUMAN20 PMIDs
TBR1_HUMAN21 PMIDs
TBKB1_HUMAN22 PMIDs
TANK_HUMAN23 PMIDs
TAGL2_HUMAN24 PMIDs
STRAP_HUMAN25 PMIDs
STK16_HUMAN26 PMIDs
STIP1_HUMAN27 PMIDs
SNX3_HUMAN28 PMIDs
SND1_HUMAN29 PMIDs
SMRC1_HUMAN30 PMIDs
SMCA4_HUMAN31 PMIDs
SMC4_HUMAN32 PMIDs
SMAP_HUMAN33 PMIDs
SLK_HUMAN34 PMIDs
SGTA_HUMAN35 PMIDs
SFXN1_HUMAN36 PMIDs
SET_HUMAN37 PMIDs
SEPT2_HUMAN38 PMIDs
SC23B_HUMAN39 PMIDs
SBDS_HUMAN40 PMIDs
SAR1A_HUMAN41 PMIDs
SAE2_HUMAN42 PMIDs
SAE1_HUMAN43 PMIDs
RT14_HUMAN44 PMIDs
RS27A_HUMAN45 PMIDs
RM14_HUMAN46 PMIDs
RM12_HUMAN47 PMIDs
RL40_HUMAN48 PMIDs
RBBP7_HUMAN49 PMIDs
RB11A_HUMAN50 PMIDs
RARA_HUMAN51 PMIDs
RADI_HUMAN52 PMIDs
RAB7A_HUMAN53 PMIDs
RAB5A_HUMAN54 PMIDs
RAB21_HUMAN55 PMIDs
RAB14_HUMAN56 PMIDs
Q9UQC1_HUMAN57 PMIDs
Q8NCK5_HUMAN58 PMIDs
Q86TW7_HUMAN59 PMIDs
Q86TQ8_HUMAN60 PMIDs
Q86SW4_HUMAN61 PMIDs
Q6PKD3_HUMAN62 PMIDs
Q6NW12_HUMAN63 PMIDs
Q6LEQ7_HUMAN64 PMIDs
Q6IBS5_HUMAN65 PMIDs
Q6FI44_HUMAN66 PMIDs
Q6FHQ0_HUMAN67 PMIDs
Q6FGG2_HUMAN68 PMIDs
Q6FGD7_HUMAN69 PMIDs
Q5SQT9_HUMAN70 PMIDs
PTH2_HUMAN71 PMIDs
PRP19_HUMAN72 PMIDs
PPAC_HUMAN73 PMIDs
PLST_HUMAN74 PMIDs
PLP2_HUMAN75 PMIDs
PIPNB_HUMAN76 PMIDs
PHB2_HUMAN77 PMIDs
PGRC2_HUMAN78 PMIDs
PGRC1_HUMAN79 PMIDs
PDCD5_HUMAN80 PMIDs
PDC6I_HUMAN81 PMIDs
PARP1_HUMAN82 PMIDs
PABP4_HUMAN83 PMIDs
PA2G4_HUMAN84 PMIDs
OTUB1_HUMAN85 PMIDs
ODO2_HUMAN86 PMIDs
NPM_HUMAN87 PMIDs
NP1L1_HUMAN88 PMIDs
NCDN_HUMAN89 PMIDs
NAT5_HUMAN90 PMIDs
NASP_HUMAN91 PMIDs
NARG1_HUMAN92 PMIDs
MTPN_HUMAN93 PMIDs
MOES_HUMAN94 PMIDs
MLEC_HUMAN95 PMIDs
ME11A_HUMAN96 PMIDs
MAVS_HUMAN97 PMIDs
LSM12_HUMAN98 PMIDs
LRC59_HUMAN99 PMIDs
LPPRC_HUMAN100 PMIDs
LG3BP_HUMAN101 PMIDs
LAGE3_HUMAN102 PMIDs
KTN1_HUMAN103 PMIDs
KIF11_HUMAN104 PMIDs
K1967_HUMAN105 PMIDs
IRF5_HUMAN106 PMIDs
IKKE_HUMAN107 PMIDs
IF2B1_HUMAN108 PMIDs
HYOU1_HUMAN109 PMIDs
HSDL2_HUMAN110 PMIDs
HS902_HUMAN111 PMIDs
HNRPQ_HUMAN112 PMIDs
GRWD1_HUMAN113 PMIDs
GRP75_HUMAN114 PMIDs
GMFB_HUMAN115 PMIDs
GLU2B_HUMAN116 PMIDs
GLRX3_HUMAN117 PMIDs
GLOD4_HUMAN118 PMIDs
G3BP1_HUMAN119 PMIDs
FHL1_HUMAN120 PMIDs
FANCG_HUMAN121 PMIDs
FABP5_HUMAN122 PMIDs
FA49B_HUMAN123 PMIDs
F162A_HUMAN124 PMIDs
F128B_HUMAN125 PMIDs
F10A1_HUMAN126 PMIDs
EZRI_HUMAN127 PMIDs
ERP29_HUMAN128 PMIDs
ERG28_HUMAN129 PMIDs
ERF3A_HUMAN130 PMIDs
EIF3M_HUMAN131 PMIDs
DOPD_HUMAN132 PMIDs
DNJB1_HUMAN133 PMIDs
DEST_HUMAN134 PMIDs
DDX5_HUMAN135 PMIDs
DDX21_HUMAN136 PMIDs
CYLD_HUMAN137 PMIDs
CYBP_HUMAN138 PMIDs
CSN2_HUMAN139 PMIDs
CPSF6_HUMAN140 PMIDs
COTL1_HUMAN141 PMIDs
CNPY2_HUMAN142 PMIDs
CLIC1_HUMAN143 PMIDs
CISD2_HUMAN144 PMIDs
CH10_HUMAN145 PMIDs
CF211_HUMAN146 PMIDs
CF125_HUMAN147 PMIDs
CDC37_HUMAN148 PMIDs
CD2A2_HUMAN149 PMIDs
CD2A1_HUMAN150 PMIDs
CCD58_HUMAN151 PMIDs
CAZA1_HUMAN152 PMIDs
CAPZB_HUMAN153 PMIDs
BTF3_HUMAN154 PMIDs
AZI2_HUMAN155 PMIDs
ARD1A_HUMAN156 PMIDs
ANXA2_HUMAN157 PMIDs
ALK_HUMAN158 PMIDs