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Target Details

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Name:Insulin-like growth factor 1 receptor
Uniprot name:IGF1R_HUMAN
Accession Numbers:B1B5Y2 P08069 Q14CV2 Q9UCC0
EC-Number:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1IGR 1JQH 1K3A 1M7N 1P4O 2OJ9 2ZM3 3D94 3F5P
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(3Z)-3-[(4-pyrrolidin-1-ylphenyl)methylidene]-1H-indol-2-one5427216BindingDB-show
(3Z)-3-[[4-(1-piperidyl)phenyl]methylidene]-1H-indol-2-one9948410BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
3-cyanoquinoline, 2924825716BindingDB-show
3[4-(1-Formylpiperazin-4-yl)benzylidenyl]-2-indolinone5941540BindingDB-show
4-(2-Methoxyethyl)phenol92516BindingDB-show
4-Anilinoquinazoline 225329048BindingDB-show
5-(2,4-dichlorobenzylidene)-1,3-thiazolidine-2,4-dione1230091BindingDB-show
ABT-86911485656BindingDB-show
AC1LDYS1727518BindingDB-show
AC1LIXJS964113BindingDB-show
AC1M5Q2K2358462BindingDB-show
AC1M62TH2365265BindingDB-show
AC1MRVMW3524522BindingDB-show
AC1NWVF05713379BindingDB-show
AC1NZ3T85874584BindingDB-show
AC1O0CK76036100BindingDB-show
AC1O6VYY6536705BindingDB-show
ADENYLYL IMIDODIPHOSPHATE33113DrugBank-show
AG-690/092910091214096BindingDB-show
AG-690/344700551204889BindingDB-show
AG-690/346530121205040BindingDB-show
AG-690/361650491731052BindingDB-show
AG-690/366300511205672BindingDB-show
AG-690/370991071206018BindingDB-show
AG-690/401247671206261BindingDB-show
AM-879/126330101774817BindingDB-show
AMG 70611667893BindingDB-show
AN-988/417198741231530BindingDB-show
AN-989/416966071810679BindingDB-show
AN-989/416967011810702BindingDB-show
anthranyl amide derivative C6398883BindingDB-show
AST-48711409972BindingDB-show
BAS 002535681206240BindingDB-show
BAS 002536111206256BindingDB-show
BAS 002536131225146BindingDB-show
BAS 003306641922265BindingDB-show
BAS 007893531565908BindingDB-show
BAS 027604855349975BindingDB-show
BMS-53692410390396BindingDB-show
BMS-75480724785538BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:54743644560358BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL1016839797919BindingDB-show
CHEMBL10305510207821BindingDB-show
CHEMBL107726946881850BindingDB-show
CHEMBL107730546881918BindingDB-show
CHEMBL107732446881957BindingDB-show
CHEMBL107732546881958BindingDB-show
CHEMBL107733946882000BindingDB-show
CHEMBL107889146881954BindingDB-show
CHEMBL107889246881955BindingDB-show
CHEMBL107899146881956BindingDB-show
CHEMBL108352746881851BindingDB-show
CHEMBL108551124762205BindingDB-show
CHEMBL108874146881819BindingDB-show
CHEMBL108893146886320BindingDB-show
CHEMBL108908224822704BindingDB-show
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CHEMBL109416411156851BindingDB-show
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CHEMBL31600910215023BindingDB-show
CHEMBL31602010236164BindingDB-show
CHEMBL31934711075591BindingDB-show
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CHEMBL50019844571812BindingDB-show
CHEMBL50209244568464BindingDB-show
CHEMBL50219844571815BindingDB-show
CHEMBL50265244571814BindingDB-show
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CHEMBL51584644581220BindingDB-show
CHEMBL51716344581248BindingDB-show
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CHEMBL59922445139989BindingDB-show
CHEMBL59942845139991BindingDB-show
CHEMBL59997446229187BindingDB-show
CHEMBL60079546232443BindingDB-show
CHEMBL60247146232555BindingDB-show
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CHEMBL8632610783444BindingDB-show
CHEMBL8643210779668BindingDB-show
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CHEMBL869459995374BindingDB-show
CHEMBL8708044321686BindingDB-show
CHEMBL8720810728035BindingDB-show
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CHEMBL8774644321301BindingDB-show
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CHEMBL8972344321317BindingDB-show
CHEMBL8980910755069BindingDB-show
CHEMBL9027710663503BindingDB-show
CHIR-26511656518BindingDB-show
CID 1142020211420202BindingDB-show
CID 99815729981572BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
FUCOSE439554DrugBank-show
Gefitinib123631BindingDB-show
GSK1904529A25124816BindingDB-show
GW-258011617559BindingDB-show
IGF-1R Inhibitor II9549305BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Intedanib9809715BindingDB-show
K000046419834BindingDB-show
Kinome_128625211575BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_353211640390BindingDB-show
Kinome_353311442386BindingDB-show
Kinome_70446886319BindingDB-show
Kinome_71446886323BindingDB-show
Kinome_72446886326BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
Mannose185698DrugBank-show
MLN805411712649BindingDB-show
Nordihyolroguaiaretic acid71398BindingDB-show
NVP-AEW54145270897BindingDB-show
oxindole i5908088BindingDB-show
Pazopanib10113978BindingDB-show
PHA-66575210461815BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Pyrrolo[2,3-d]pyrimidine 16539952BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1088_Selleck9825149BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
Scopolamine5184BindingDB-show
Semaxinib5329098BindingDB-show
Serotonin hydrochloride160436BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
ST0888051218955BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
STK1144262379240BindingDB-show
STK1556431205381BindingDB-show
STK2448871232267BindingDB-show
SU 43126450842BindingDB-show
SU-1481310138259BindingDB-show
su54025289418BindingDB-show
substituted benzimidazole, 625218685BindingDB-show
substituted benzimidazole, 725218686BindingDB-show
substituted benzimidazole, 824180536BindingDB-show
substituted benzimidazole, 925218687BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Tyrphostin AG 5385328760BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
Vatalanib succinate151193BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
ZINC001369421538822BindingDB-show
ZINC005750645427224BindingDB-show
ZINC005861935293755BindingDB-show
ZINC009738101204893BindingDB-show
ZINC009758271206252BindingDB-show
ZINC009758281206254BindingDB-show
ZINC009758391206264BindingDB-show
ZINC009758651206279BindingDB-show
ZINC009822411210312BindingDB-show
ZINC010050521227452BindingDB-show
ZINC010050581227456BindingDB-show
ZINC010129201232220BindingDB-show
ZINC010129801232262BindingDB-show
ZINC010137011232669BindingDB-show
ZINC010139081232814BindingDB-show
ZINC010208551237187BindingDB-show
ZINC020684571731078BindingDB-show
ZINC031174115753500BindingDB-show
ZINC032806632396126BindingDB-show
ZINC040383565707304BindingDB-show
ZINC057200826155669BindingDB-show
Synonyms:
CD221
IGF-I receptor
Insulin-like growth factor 1 receptor
Insulin-like growth factor I receptor
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
INSR_HUMAN72.456.9
Q86WY9_HUMAN38.929.3
EGFR_HUMAN3320.4
EGFR_MOUSE3220.5
MET_HUMAN31.519.1
JAK3_HUMAN31.219.5
EGFR_DROME3119.4
EPHB1_HUMAN30.918.8
JAK2_HUMAN30.817.5
VGFR3_HUMAN30.518.2
ERBB2_HUMAN30.420
JAK3_MOUSE30.318.7
EPHB2_MOUSE29.917
ERBB4_HUMAN29.919.3
P93098_CERPU29.417.7
ALK_HUMAN29.418.2
METH_ECOLI29.317.2
VGFR1_HUMAN29.215.8
JAK3_RAT28.918.4
VGFR2_HUMAN28.818.3
DPOL_HCMVA28.617.3
Q59FN5_HUMAN28.515.8
Q9ZWQ6_ADICA28.517.1
JAK2_RAT2817.5
Q59FL8_HUMAN27.817
DPOL_EBVB927.115.7
TOP2_YEAST27.115.1
KIT_HUMAN2715.5
Q6IQ28_HUMAN26.915.5
AT8A1_HUMAN26.515.7
Protein-Protein Interactions: