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Target Details

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Name:Epoxide hydrolase 2
Uniprot name:HYES_HUMAN
Accession Numbers:B2Z3B1 P34913 Q16764 Q9HBJ1 Q9HBJ2
EC-Number:3.3.2.10
Organism:Homo sapiens
Human
PDB IDs:1S8O 1VJ5 1ZD2 1ZD3 1ZD4 1ZD5
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1,3-bis(3,4-dichlorophenyl)urea95783BindingDB-show
1-(1-adamantyl)-3-(4-methoxyphenyl)urea3545369BindingDB-show
1-(3-chlorophenyl)-3-cyclohexylurea751320BindingDB-show
1-(4-chlorophenyl)-3-cyclohexylurea238899BindingDB-show
1-cyclohexyl-3-(3-methoxypropyl)urea4063047BindingDB-show
1-cyclohexyl-3-(4-hydroxyphenyl)urea4051140BindingDB-show
1-cyclohexyl-3-(4-methoxyphenyl)urea3397178BindingDB-show
1-cyclohexyl-3-[2-(hydroxymethyl)phenyl]urea4550519BindingDB-show
1-cyclopentyl-3-dodecyl-urea11033798BindingDB-show
4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID6420119BindingDB-show
5-benzyl-N-phenyl-1,3,4-oxadiazol-2-amine4183634BindingDB-show
6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID6420120BindingDB-show
AC1MG4WB2955557BindingDB-show
AC1OO3GT7545432BindingDB-show
AC1OO4S97546299BindingDB-show
AC1PMENG9166073BindingDB-show
AC1Q75NN11020253BindingDB-show
AN-329/42581087974401BindingDB-show
ARONIS01525817205433BindingDB-show
ASN 064823093221297BindingDB-show
BAS 001026913090774BindingDB-show
BAS 077844061090889BindingDB-show
Benzothiazole, 2-(benzylamino)-617555BindingDB-show
Benzoxazole, 2-(benzylamino)-563453BindingDB-show
CBMicro_031991880925BindingDB-show
CHEMBL107778046882917BindingDB-show
CHEMBL107778146882918BindingDB-show
CHEMBL107796346883035BindingDB-show
CHEMBL107823246882986BindingDB-show
CHEMBL107826446882874BindingDB-show
CHEMBL107826542643589BindingDB-show
CHEMBL107833646883033BindingDB-show
CHEMBL107833746883034BindingDB-show
CHEMBL107835346882875BindingDB-show
CHEMBL107835446882876BindingDB-show
CHEMBL107845242643591BindingDB-show
CHEMBL107856542644088BindingDB-show
CHEMBL107862846882973BindingDB-show
CHEMBL107865746882919BindingDB-show
CHEMBL107871546883032BindingDB-show
CHEMBL107875542644084BindingDB-show
CHEMBL107906142646202BindingDB-show
CHEMBL107914046882969BindingDB-show
CHEMBL107924446882970BindingDB-show
CHEMBL107924546882971BindingDB-show
CHEMBL107924646882972BindingDB-show
CHEMBL107925642646199BindingDB-show
CHEMBL107925746882987BindingDB-show
CHEMBL107925846882988BindingDB-show
CHEMBL107929046882949BindingDB-show
CHEMBL107929146882950BindingDB-show
CHEMBL107929246882951BindingDB-show
CHEMBL107936044555473BindingDB-show
CHEMBL107936142646450BindingDB-show
CHEMBL107936246883473BindingDB-show
CHEMBL108007646883474BindingDB-show
CHEMBL108097446883508BindingDB-show
CHEMBL108097546883509BindingDB-show
CHEMBL108170346883510BindingDB-show
CHEMBL108268446871778BindingDB-show
CHEMBL108362246700789BindingDB-show
CHEMBL108574346891216BindingDB-show
CHEMBL108574446871779BindingDB-show
CHEMBL108574546891217BindingDB-show
CHEMBL108574646891218BindingDB-show
CHEMBL108669346889055BindingDB-show
CHEMBL108669446889056BindingDB-show
CHEMBL108682046889057BindingDB-show
CHEMBL108682110072550BindingDB-show
CHEMBL108685124945680BindingDB-show
CHEMBL108698246889138BindingDB-show
CHEMBL108706232978914BindingDB-show
CHEMBL108734446888913BindingDB-show
CHEMBL108734546888914BindingDB-show
CHEMBL108734646888915BindingDB-show
CHEMBL108745046889083BindingDB-show
CHEMBL108746824945520BindingDB-show
CHEMBL108749024945521BindingDB-show
CHEMBL108749124945676BindingDB-show
CHEMBL108749246889110BindingDB-show
CHEMBL108771646888916BindingDB-show
CHEMBL108772224809976BindingDB-show
CHEMBL108772346889226BindingDB-show
CHEMBL108785346888977BindingDB-show
CHEMBL108785446888978BindingDB-show
CHEMBL108786224945438BindingDB-show
CHEMBL108786417298177BindingDB-show
CHEMBL108797746888979BindingDB-show
CHEMBL108798346889249BindingDB-show
CHEMBL108808324894571BindingDB-show
CHEMBL108808446889165BindingDB-show
CHEMBL108811824945437BindingDB-show
CHEMBL108822746889204BindingDB-show
CHEMBL108822824895838BindingDB-show
CHEMBL108835024895839BindingDB-show
CHEMBL108835124894561BindingDB-show
CHEMBL108836624894570BindingDB-show
CHEMBL108837324945361BindingDB-show
CHEMBL108842024766020BindingDB-show
CHEMBL108854524945677BindingDB-show
CHEMBL108854624945761BindingDB-show
CHEMBL108854724945759BindingDB-show
CHEMBL108856324945518BindingDB-show
CHEMBL108856423729132BindingDB-show
CHEMBL108856546889139BindingDB-show
CHEMBL108868224945522BindingDB-show
CHEMBL108868746889270BindingDB-show
CHEMBL108868846889271BindingDB-show
CHEMBL108868946889272BindingDB-show
CHEMBL108869846889036BindingDB-show
CHEMBL108869946889037BindingDB-show
CHEMBL108870046889038BindingDB-show
CHEMBL109547046888846BindingDB-show
CHEMBL109547146888847BindingDB-show
CHEMBL109547246888848BindingDB-show
CHEMBL109611324945519BindingDB-show
CHEMBL109611446888872BindingDB-show
CHEMBL109611524945760BindingDB-show
CHEMBL109645224945440BindingDB-show
CHEMBL109717924945591BindingDB-show
CHEMBL109752224945762BindingDB-show
CHEMBL109752346888804BindingDB-show
CHEMBL109752446888805BindingDB-show
CHEMBL109768424945594BindingDB-show
CHEMBL109846846888844BindingDB-show
CHEMBL109846946888845BindingDB-show
CHEMBL109936046889111BindingDB-show
CHEMBL109939024894562BindingDB-show
CHEMBL1144811832044BindingDB-show
CHEMBL1152411139699BindingDB-show
CHEMBL1165844267276BindingDB-show
CHEMBL12345659820664BindingDB-show
CHEMBL125616347379737BindingDB-show
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CHEMBL125787949783004BindingDB-show
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CHEMBL125798949783005BindingDB-show
CHEMBL125799049783006BindingDB-show
CHEMBL125810549783007BindingDB-show
CHEMBL125810649783008BindingDB-show
CHEMBL125810749783009BindingDB-show
CHEMBL125821949783010BindingDB-show
CHEMBL125822049783213BindingDB-show
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CHEMBL125833649783216BindingDB-show
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CHEMBL125844749783218BindingDB-show
CHEMBL125844849783219BindingDB-show
CHEMBL125844949783220BindingDB-show
CHEMBL125855649783422BindingDB-show
CHEMBL125855749783423BindingDB-show
CHEMBL125855849783424BindingDB-show
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CHEMBL125867049783427BindingDB-show
CHEMBL125878449783428BindingDB-show
CHEMBL125878549780161BindingDB-show
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CHEMBL127149752949345BindingDB-show
CHEMBL127149852944428BindingDB-show
CHEMBL127155052942123BindingDB-show
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CHEMBL127160752948184BindingDB-show
CHEMBL127160850899467BindingDB-show
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CHEMBL127171252940693BindingDB-show
CHEMBL19176711186744BindingDB-show
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CHEMBL19227211416405BindingDB-show
CHEMBL19229911209573BindingDB-show
CHEMBL19247011379743BindingDB-show
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CHEMBL21417924849240BindingDB-show
CHEMBL21450544417013BindingDB-show
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CHEMBL21456824849907BindingDB-show
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CHEMBL21473544417126BindingDB-show
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CHEMBL21616444418698BindingDB-show
CHEMBL21616544418699BindingDB-show
CHEMBL21621944418639BindingDB-show
CHEMBL21622044418640BindingDB-show
CHEMBL21628714322900BindingDB-show
CHEMBL21659244418697BindingDB-show
CHEMBL21771144416809BindingDB-show
CHEMBL21775844417034BindingDB-show
CHEMBL21794244419715BindingDB-show
CHEMBL21806144418667BindingDB-show
CHEMBL21811344418696BindingDB-show
CHEMBL21835344418605BindingDB-show
CHEMBL21835444418634BindingDB-show
CHEMBL21840244418693BindingDB-show
CHEMBL21895444418706BindingDB-show
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CHEMBL21902444418617BindingDB-show
CHEMBL21902644418643BindingDB-show
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CHEMBL21904344418689BindingDB-show
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CHEMBL21949044418694BindingDB-show
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CHEMBL21952844418704BindingDB-show
CHEMBL21959544418632BindingDB-show
CHEMBL21959644418653BindingDB-show
CHEMBL21959744418654BindingDB-show
CHEMBL21969344418623BindingDB-show
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CHEMBL21974744418646BindingDB-show
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CHEMBL22002844418619BindingDB-show
CHEMBL22002944418620BindingDB-show
CHEMBL22041511160856BindingDB-show
CHEMBL22090844419697BindingDB-show
CHEMBL22101544419709BindingDB-show
CHEMBL22144611610101BindingDB-show
CHEMBL22173744419705BindingDB-show
CHEMBL22179244419724BindingDB-show
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CHEMBL22208044419692BindingDB-show
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CHEMBL22390011212321BindingDB-show
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CHEMBL22426644422288BindingDB-show
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CHEMBL22435911373914BindingDB-show
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CHEMBL24246011525463BindingDB-show
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CHEMBL24406711494940BindingDB-show
CHEMBL24406811502402BindingDB-show
CHEMBL24419211553060BindingDB-show
CHEMBL24419316756172BindingDB-show
CHEMBL24440616757353BindingDB-show
CHEMBL24440716757354BindingDB-show
CHEMBL24500644427449BindingDB-show
CHEMBL24512723631475BindingDB-show
CHEMBL24514123631733BindingDB-show
CHEMBL24514223631476BindingDB-show
CHEMBL24514323631734BindingDB-show
CHEMBL2451449927748BindingDB-show
CHEMBL24514523631477BindingDB-show
CHEMBL24514611574457BindingDB-show
CHEMBL24514711552964BindingDB-show
CHEMBL24514811532957BindingDB-show
CHEMBL24515023631821BindingDB-show
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CHEMBL26459144418638BindingDB-show
CHEMBL26502411268605BindingDB-show
CHEMBL26562444418691BindingDB-show
CHEMBL30207011185623BindingDB-show
CHEMBL30211611211985BindingDB-show
CHEMBL30250511187224BindingDB-show
CHEMBL30266411404645BindingDB-show
CHEMBL30270411305487BindingDB-show
CHEMBL30544611200931BindingDB-show
CHEMBL30864211020645BindingDB-show
CHEMBL30866511486246BindingDB-show
CHEMBL30888011771739BindingDB-show
CHEMBL36402011186477BindingDB-show
CHEMBL37365544419689BindingDB-show
CHEMBL37390244418703BindingDB-show
CHEMBL37473011581328BindingDB-show
CHEMBL37488844418705BindingDB-show
CHEMBL37511344422289BindingDB-show
CHEMBL37524011362503BindingDB-show
CHEMBL37583944418649BindingDB-show
CHEMBL37596744418707BindingDB-show
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CHEMBL7023111397754BindingDB-show
Methyl 6-(1-adamantylcarbamoylamino)hexanoate3759481BindingDB-show
MLS000061067742677BindingDB-show
MLS0005307881306384BindingDB-show
MLS0005710954009612BindingDB-show
MLS00241556144142782BindingDB-show
N,N'-Dicyclohexylurea4277BindingDB-show
N-(1-adamantyl)dodecanamide5071820BindingDB-show
N-(3,3-diphenylpropyl)benzamide1220236BindingDB-show
N-(3-phenylpropyl)pyridine-3-carboxamide4648643BindingDB-show
N-cyclohexyl-2-(4-methoxyphenyl)acetamide729989BindingDB-show
N-Cyclohexyl-2-phenylacetamide82500BindingDB-show
N-cyclohexyl-4-phenylbutanamide288831BindingDB-show
N-CYCLOHEXYL-N'-(4-IODOPHENYL)UREA4357DrugBank-show
N-CYCLOHEXYL-N'-DECYLUREA4359BindingDB-show
N-CYCLOHEXYL-N'-PHENYLUREA13451BindingDB-show
NC34149241BindingDB-show
NSC98656263942BindingDB-show
Oprea1_42530117375075BindingDB-show
Oprea1_65037024160013BindingDB-show
Oprea1_71228424132341BindingDB-show
Oprea1_81778625036176BindingDB-show
Oprea1_86677911379742BindingDB-show
STK1408224450442BindingDB-show
STK1554301090888BindingDB-show
STK2070142235217BindingDB-show
STK2227641121089BindingDB-show
STK386760839616BindingDB-show
Tomaxithen2733526DrugBank-show
Urea-based compound, 1425093348BindingDB-show
Urea-based compound, 1511425995BindingDB-show
Urea-based compound, 1625093349BindingDB-show
Urea-based compound, 1810069117BindingDB-show
Urea-based compound, 1911280933BindingDB-show
Urea-based compound, 2016038368BindingDB-show
Urea-based compound, 2325093351BindingDB-show
Urea-based compound, 2625093353BindingDB-show
ZINC00451519880922BindingDB-show
ZINC022120421845020BindingDB-show
ZINC025464652061174BindingDB-show
ZINC026471242110176BindingDB-show
ZINC028535052207161BindingDB-show
ZINC038950725029871BindingDB-show
ZINC044018963530525BindingDB-show
ZINC055090045193384BindingDB-show
Synonyms:
CEH
Cytosolic epoxide hydrolase
Epoxide hydratase
Epoxide hydrolase 2
SEH
Soluble epoxide hydrolase
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
HYES_MOUSE86.773
RBCMT_PEA33.318.3
A3LMT4_PICST33.218.2
FIXL_BRAJA32.317.5
HCP_DESVH31.217.2
PDPK1_HUMAN31.116.2
Q86WD1_HUMAN30.916.7
ABDH_ECOLI30.617.2
CYSJ_ECOLI30.618.7
MAOX_HUMAN30.517.7
MET3_PENCH30.318.2
Q6XK24_MOUSE30.218.7
GATB_HUMAN29.816.3
Q8GB52_9VIBR29.818
DOT1_YEAST29.717.7
PHOQ_ECOLI29.517.4
SPCS_HUMAN29.516.5
SAP_HUMAN29.517.6
ERG1_RAT29.417.5
MEMA_METCA29.316.9
PDC1_YEAST29.217.3
SUOX_HUMAN29.118.1
Q8VNU2_DESDE29.117.3
SGPL1_HUMAN29.116
QCR1_BOVIN29.117.8
IMDH2_HUMAN2917.8
KMO_RAT28.917
HEM0_HUMAN28.917.3
AMO_PEA28.917.3
FRDA_SHEFR28.816.7
Protein-Protein Interactions:
Uniprot nameSource
NPS3A_HUMANPMID 16169070