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Target Details

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Name:Histamine H4 receptor
Uniprot name:HRH4_HUMAN
Accession Numbers:Q4G0I6 Q9GZQ0 Q9H3N8
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(1R,2S)-2-(3H-imidazol-4-yl)cyclopropan-1-amine10986211BindingDB-show
(1R,2S)-2-(3H-imidazol-4-yl)cyclopropan-1-amine10374457BindingDB-show
(1R,2S)-2-(3H-imidazol-4-yl)cyclopropan-1-amine11804748BindingDB-show
(1R,2S)-2-(3H-imidazol-4-yl)cyclopropan-1-amine10103168BindingDB-show
(5-chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone4908365BindingDB-show
(5-fluoro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone4906599BindingDB-show
(R)-(+)-Terfenadine7048803BindingDB-show
1H-Imidazole-4-ethanamine, alpha-methyl-, (alphaR)-156615BindingDB-show
1H-Imidazole-4-propanamine170389BindingDB-show
1H-indol-2-yl-(4-methylpiperazin-1-yl)methanone4060730BindingDB-show
2-(3-Bromophenyl)histamine23786499BindingDB-show
2-Aminopyrimidine analog., 425130235BindingDB-show
2-arylbenzimidazole lead compound 111451949BindingDB-show
2-Methylhistamine91613BindingDB-show
2-Thiazolylethylamine87653BindingDB-show
2-[(1S,2R)-2-(3H-imidazol-4-yl)cyclopropyl]ethanamine11829635BindingDB-show
2-[(1S,2R)-2-(3H-imidazol-4-yl)cyclopropyl]ethanamine10154137BindingDB-show
2-[(4-methylpiperazin-1-yl)methyl]-1H-indole4242418BindingDB-show
2-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,511948707BindingDB-show
2-[4-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-tri11676174BindingDB-show
3-(3H-imidazol-4-yl)propyl N-heptan-2-ylcarbamate10515993BindingDB-show
3-(3H-imidazol-4-yl)propyl N-heptan-2-ylcarbamate9951970BindingDB-show
3-(3H-imidazol-4-yl)propyl N-hexan-2-ylcarbamate10243990BindingDB-show
3-(3H-imidazol-4-yl)propyl N-hexan-2-ylcarbamate10777275BindingDB-show
3-(3H-imidazol-4-yl)propyl N-[(2S)-butan-2-yl]carbamate10680721BindingDB-show
4-Methylhistamine37463BindingDB-show
4457698444576984BindingDB-show
6-aryl-2-aminopyrimidine, 325129523BindingDB-show
8R-lisuride11957615BindingDB-show
A-98730625109291BindingDB-show
AC1L4URV164435BindingDB-show
AC1LJDZ7921599BindingDB-show
AC1MGZLJ2994072BindingDB-show
AC1N0AUW3934857BindingDB-show
AC1O3VDW6338986BindingDB-show
Amselamine9990475BindingDB-show
Amthamine126688BindingDB-show
AO-476/411449107015108BindingDB-show
Azatadine19861BindingDB-show
BAS 00933703762810BindingDB-show
BAS 06575347753256BindingDB-show
BRN 0541572206876BindingDB-show
BURIMAMIDE3032915BindingDB-show
Carbamazapine2756BindingDB-show
Carboxyterfenadine3348BindingDB-show
Cetirizine2678BindingDB-show
CHEBI:58686344576955BindingDB-show
CHEBI:58692944576990BindingDB-show
CHEMBL107626710776393BindingDB-show
CHEMBL107686746885240BindingDB-show
CHEMBL107974710715823BindingDB-show
CHEMBL108154110515050BindingDB-show
CHEMBL108171810800875BindingDB-show
CHEMBL108229646890592BindingDB-show
CHEMBL108260946890628BindingDB-show
CHEMBL108277146890546BindingDB-show
CHEMBL108277246890547BindingDB-show
CHEMBL108285146890120BindingDB-show
CHEMBL108285246890121BindingDB-show
CHEMBL108308446890548BindingDB-show
CHEMBL108308546890549BindingDB-show
CHEMBL108309746890626BindingDB-show
CHEMBL108309846890627BindingDB-show
CHEMBL108309946890629BindingDB-show
CHEMBL108315946890073BindingDB-show
CHEMBL108316046890074BindingDB-show
CHEMBL108316246235428BindingDB-show
CHEMBL108435446890071BindingDB-show
CHEMBL108435546890072BindingDB-show
CHEMBL108480946890589BindingDB-show
CHEMBL108481046890590BindingDB-show
CHEMBL108481146890591BindingDB-show
CHEMBL108486946890022BindingDB-show
CHEMBL108540346890200BindingDB-show
CHEMBL108580246890674BindingDB-show
CHEMBL108580346890675BindingDB-show
CHEMBL108580446890676BindingDB-show
CHEMBL108587246890167BindingDB-show
CHEMBL108603846890677BindingDB-show
CHEMBL108608546890019BindingDB-show
CHEMBL108610546890166BindingDB-show
CHEMBL108632746890020BindingDB-show
CHEMBL108632846890021BindingDB-show
CHEMBL108634446890122BindingDB-show
CHEMBL108646046890545BindingDB-show
CHEMBL108885946885178BindingDB-show
CHEMBL108888846884997BindingDB-show
CHEMBL108888916656870BindingDB-show
CHEMBL108916646885179BindingDB-show
CHEMBL108916746885180BindingDB-show
CHEMBL109019016656872BindingDB-show
CHEMBL109051946885128BindingDB-show
CHEMBL109052046885129BindingDB-show
CHEMBL109053116656871BindingDB-show
CHEMBL109053246884998BindingDB-show
CHEMBL109065546884996BindingDB-show
CHEMBL109138946885127BindingDB-show
CHEMBL109155916656869BindingDB-show
CHEMBL109156746885130BindingDB-show
CHEMBL109156846885131BindingDB-show
CHEMBL109156916656874BindingDB-show
CHEMBL109172946885177BindingDB-show
CHEMBL109187416718567BindingDB-show
CHEMBL109187525112105BindingDB-show
CHEMBL109206446885239BindingDB-show
CHEMBL109233011695388BindingDB-show
CHEMBL109233146884945BindingDB-show
CHEMBL109233211709443BindingDB-show
CHEMBL109254211682208BindingDB-show
CHEMBL109254346885241BindingDB-show
CHEMBL109288046885181BindingDB-show
CHEMBL109288146885182BindingDB-show
CHEMBL109293311566111BindingDB-show
CHEMBL109293411638468BindingDB-show
CHEMBL109313811709905BindingDB-show
CHEMBL109313946885296BindingDB-show
CHEMBL109343846885297BindingDB-show
CHEMBL109343946885298BindingDB-show
CHEMBL109823046222048BindingDB-show
CHEMBL117275446912441BindingDB-show
CHEMBL117277546912442BindingDB-show
CHEMBL12022111609325BindingDB-show
CHEMBL12059111594278BindingDB-show
CHEMBL12085411687917BindingDB-show
CHEMBL12167910083861BindingDB-show
CHEMBL124333546929551BindingDB-show
CHEMBL124336646929553BindingDB-show
CHEMBL124336746929554BindingDB-show
CHEMBL124339446929647BindingDB-show
CHEMBL124339546929648BindingDB-show
CHEMBL12813411821243BindingDB-show
CHEMBL1282529966927BindingDB-show
CHEMBL12847011013044BindingDB-show
CHEMBL12850511120826BindingDB-show
CHEMBL12850611021530BindingDB-show
CHEMBL1286139923162BindingDB-show
CHEMBL12895810923241BindingDB-show
CHEMBL12902610934567BindingDB-show
CHEMBL12943611066922BindingDB-show
CHEMBL1294449900313BindingDB-show
CHEMBL12948811065080BindingDB-show
CHEMBL12954010967174BindingDB-show
CHEMBL1585959851785BindingDB-show
CHEMBL17923411349921BindingDB-show
CHEMBL18595110446295BindingDB-show
CHEMBL18728511572877BindingDB-show
CHEMBL19747710018335BindingDB-show
CHEMBL1990629839217BindingDB-show
CHEMBL19923111630326BindingDB-show
CHEMBL20054611615753BindingDB-show
CHEMBL20959816082824BindingDB-show
CHEMBL21000616082864BindingDB-show
CHEMBL21270516082822BindingDB-show
CHEMBL21313316082858BindingDB-show
CHEMBL21325016082820BindingDB-show
CHEMBL21341316082862BindingDB-show
CHEMBL21388616082828BindingDB-show
CHEMBL21391211846300BindingDB-show
CHEMBL21415616082826BindingDB-show
CHEMBL21431116082831BindingDB-show
CHEMBL21431216082833BindingDB-show
CHEMBL21562716082866BindingDB-show
CHEMBL21562816082856BindingDB-show
CHEMBL21993011258458BindingDB-show
CHEMBL21998211750684BindingDB-show
CHEMBL22093311258459BindingDB-show
CHEMBL22093411212855BindingDB-show
CHEMBL22121011340020BindingDB-show
CHEMBL22121111408069BindingDB-show
CHEMBL22349011293460BindingDB-show
CHEMBL22942916737207BindingDB-show
CHEMBL26852511565330BindingDB-show
CHEMBL30607710060213BindingDB-show
CHEMBL30891310017821BindingDB-show
CHEMBL30981910105117BindingDB-show
CHEMBL3317739883231BindingDB-show
CHEMBL33177510244311BindingDB-show
CHEMBL3332209992865BindingDB-show
CHEMBL33800110860228BindingDB-show
CHEMBL3380519878733BindingDB-show
CHEMBL3389379944571BindingDB-show
CHEMBL33897211623296BindingDB-show
CHEMBL34074010988959BindingDB-show
CHEMBL34108710399535BindingDB-show
CHEMBL36249510444761BindingDB-show
CHEMBL36440011587279BindingDB-show
CHEMBL37013511601630BindingDB-show
CHEMBL37357911224088BindingDB-show
CHEMBL37626811751419BindingDB-show
CHEMBL37695416082852BindingDB-show
CHEMBL37757216082860BindingDB-show
CHEMBL37851116082854BindingDB-show
CHEMBL37861916006947BindingDB-show
CHEMBL38227610083188BindingDB-show
CHEMBL38338410244243BindingDB-show
CHEMBL38734211189343BindingDB-show
CHEMBL43600344351617BindingDB-show
CHEMBL47141325149521BindingDB-show
CHEMBL47244125149613BindingDB-show
CHEMBL47632311697697BindingDB-show
CHEMBL48340023151209BindingDB-show
CHEMBL48554311973780BindingDB-show
CHEMBL48824811581337BindingDB-show
CHEMBL48949324825514BindingDB-show
CHEMBL49223125129169BindingDB-show
CHEMBL49267725130914BindingDB-show
CHEMBL49301424825515BindingDB-show
CHEMBL49328125071940BindingDB-show
CHEMBL49409325128822BindingDB-show
CHEMBL49489025130576BindingDB-show
CHEMBL49498224825522BindingDB-show
CHEMBL50233925149708BindingDB-show
CHEMBL50234725068753BindingDB-show
CHEMBL50360521638785BindingDB-show
CHEMBL50736011539020BindingDB-show
CHEMBL50954025071319BindingDB-show
CHEMBL51389325099115BindingDB-show
CHEMBL51421711632103BindingDB-show
CHEMBL52199525128823BindingDB-show
CHEMBL52199625071004BindingDB-show
CHEMBL52267325101945BindingDB-show
CHEMBL52322525128824BindingDB-show
CHEMBL56038644250288BindingDB-show
CHEMBL56583345487384BindingDB-show
CHEMBL57029644469273BindingDB-show
CHEMBL59310316061961BindingDB-show
CHEMBL59344846228070BindingDB-show
CHEMBL59355146228083BindingDB-show
CHEMBL59402246228101BindingDB-show
CHEMBL59426646228087BindingDB-show
CHEMBL59446846228160BindingDB-show
CHEMBL59449024797248BindingDB-show
CHEMBL59449124798596BindingDB-show
CHEMBL59469446228161BindingDB-show
CHEMBL59472145257133BindingDB-show
CHEMBL59473145257131BindingDB-show
CHEMBL59494945257134BindingDB-show
CHEMBL59497346228092BindingDB-show
CHEMBL59518045257132BindingDB-show
CHEMBL59521546228125BindingDB-show
CHEMBL59541346228100BindingDB-show
CHEMBL59544911957735BindingDB-show
CHEMBL59563946228133BindingDB-show
CHEMBL59588046228143BindingDB-show
CHEMBL59606746225253BindingDB-show
CHEMBL59634846228069BindingDB-show
CHEMBL59655146228114BindingDB-show
CHEMBL59656246228071BindingDB-show
CHEMBL59829146231557BindingDB-show
CHEMBL60871746228113BindingDB-show
CHEMBL60886446228076BindingDB-show
CHEMBL60916146228132BindingDB-show
CHEMBL60928946228158BindingDB-show
CHEMBL61049246231604BindingDB-show
CHEMBL61062646228082BindingDB-show
CHEMBL61213146228126BindingDB-show
CHEMBL7060310422468BindingDB-show
CHEMBL723729974306BindingDB-show
CHEMBL7242410466840BindingDB-show
CHEMBL7243110017000BindingDB-show
CHEMBL7257110085839BindingDB-show
CHEMBL7276910060212BindingDB-show
ciproxifan6422124BindingDB-show
Claratyne Decongestant3957BindingDB-show
clobenpropit2790BindingDB-show
Clozapine2818BindingDB-show
Clozapine2818DrugBank-show
Clozapine2818SuperTargetPMID 16860312show
Conessinum441082BindingDB-show
Demethylbetahistine75919BindingDB-show
Desmethylloxapine2170BindingDB-show
Dimaprit Dihydrochloride3077BindingDB-show
EBASTINE3191BindingDB-show
Gastrodomina5702160BindingDB-show
histamine774BindingDB-show
Histaprodifen10447834BindingDB-show
Hydroxizinum3658BindingDB-show
Imbutamine13499360BindingDB-show
imetit3692BindingDB-show
Immepip3035842BindingDB-show
Immethridine9989505BindingDB-show
Impentamine9793868BindingDB-show
IMPROMIDINE41376BindingDB-show
Iodophenpropit3035746BindingDB-show
Iodoproxyfan132937BindingDB-show
Loxapinsuccinate3964BindingDB-show
Methimepip11313837BindingDB-show
methylhistamine912BindingDB-show
Mifentidine71263BindingDB-show
Mizolastine65906BindingDB-show
Octoclothepine1238BindingDB-show
Proxyfan6421522BindingDB-show
Pyranisamine4992BindingDB-show
Ranitidine hydrochloride3001055BindingDB-show
S-(+)-Sopromidine24825631BindingDB-show
SMR0001180403201696BindingDB-show
Sopromidine210319BindingDB-show
STK0458472063135BindingDB-show
STK1664494242975BindingDB-show
STK630143756701BindingDB-show
Thioperamide3035905BindingDB-show
TIOTIDINE50287BindingDB-show
Tocris-05726603865BindingDB-show
UR-AK2425149335BindingDB-show
VUF 832810176414BindingDB-show
ZINC014093116346624BindingDB-show
[2-(3H-imidazol-4-yl)cyclopropyl]methanamine11116130BindingDB-show
[2-(3H-imidazol-4-yl)cyclopropyl]methanamine10942498BindingDB-show
[2-(3H-imidazol-4-yl)cyclopropyl]methanamine11126319BindingDB-show
[2-(3H-imidazol-4-yl)cyclopropyl]methanamine11094685BindingDB-show
Synonyms:
AXOR35
G-protein coupled receptor 105
GPRv53
HH4R
Histamine H4 receptor
Pfi-013
SP9144
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
HRH3_HUMAN48.536.1
Q9P2Q4_HUMAN46.524.7
5HT1F_HUMAN46.124.8
5HT1D_HUMAN43.323
5HT5A_HUMAN43.123.7
ACM2_HUMAN42.923.3
ACM1_HUMAN42.824.9
DRD3_HUMAN42.326.8
5HT1B_HUMAN41.723.9
AA3R_HUMAN41.522.9
ADA2A_HUMAN41.224.7
DRD4_MOUSE4121.3
Q5ZGX3_HUMAN40.720.8
5HT1A_HUMAN40.720.8
ACM4_HUMAN40.522.8
5HT1E_HUMAN40.424
ADA2B_HUMAN40.123.7
TAAR1_HUMAN4021.8
Q684M0_HUMAN39.724.9
AA2BR_HUMAN39.224.2
AA3R_MOUSE39.123.2
HRH2_HUMAN39.120.1
HRH1_HUMAN39.121.6
AA3R_RAT39.123
Q3U4C5_MOUSE39.123.4
ADA2C_HUMAN38.922.1
Q4PKD9_RAT38.923
HRH1_BOVIN38.822.7
DRD2_HUMAN38.722.4
DRD2_RAT38.522.5
Protein-Protein Interactions:
No data available