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Target Details

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Name:Histamine H2 receptor
Uniprot name:HRH2_HUMAN
Accession Numbers:P25021 Q14464
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
(1R,2S)-2-(3H-imidazol-4-yl)cyclopropan-1-amine10986211BindingDB-show
(1R,2S)-2-(3H-imidazol-4-yl)cyclopropan-1-amine10374457BindingDB-show
(1R,2S)-2-(3H-imidazol-4-yl)cyclopropan-1-amine11804748BindingDB-show
(1R,2S)-2-(3H-imidazol-4-yl)cyclopropan-1-amine10103168BindingDB-show
(5-chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone4908365BindingDB-show
2-[(1S,2R)-2-(3H-imidazol-4-yl)cyclopropyl]ethanamine11829635BindingDB-show
2-[(1S,2R)-2-(3H-imidazol-4-yl)cyclopropyl]ethanamine10154137BindingDB-show
2-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,511948707BindingDB-show
2-[4-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-tri11676174BindingDB-show
A-98730625109291BindingDB-show
AC1L1H5P29298BindingDB-show
AC1LCWE1657345BindingDB-show
Acetophenazinum17676SuperTargetPMID 7311show
Ametazole7741DrugBank-show
Ametazole7741SuperTarget-show
Amitriprolidine2160BindingDB-show
Carbamazapine2756DrugBank-show
Carbamazapine2756SuperTarget2 PMIDsshow
CHEBI:64830344372910BindingDB-show
CHEMBL10163444334037BindingDB-show
CHEMBL10169144334430BindingDB-show
CHEMBL10174844334038BindingDB-show
CHEMBL10233144333988BindingDB-show
CHEMBL10238444334025BindingDB-show
CHEMBL10239044334252BindingDB-show
CHEMBL10250744334193BindingDB-show
CHEMBL10284044334214BindingDB-show
CHEMBL10292544334212BindingDB-show
CHEMBL10292944334235BindingDB-show
CHEMBL10302710003483BindingDB-show
CHEMBL10382844334281BindingDB-show
CHEMBL10434444334406BindingDB-show
CHEMBL10461844334396BindingDB-show
CHEMBL10480844334395BindingDB-show
CHEMBL10480910343536BindingDB-show
CHEMBL10499444334503BindingDB-show
CHEMBL10507144334369BindingDB-show
CHEMBL10716244334781BindingDB-show
CHEMBL10729344334782BindingDB-show
CHEMBL108015546880498BindingDB-show
CHEMBL108038946880628BindingDB-show
CHEMBL108055646880629BindingDB-show
CHEMBL108073546880630BindingDB-show
CHEMBL108075546880673BindingDB-show
CHEMBL108090746880631BindingDB-show
CHEMBL108092646880674BindingDB-show
CHEMBL108121246880569BindingDB-show
CHEMBL108125446880672BindingDB-show
CHEMBL108164846880462BindingDB-show
CHEMBL108164946880463BindingDB-show
CHEMBL108220946880566BindingDB-show
CHEMBL108221046880567BindingDB-show
CHEMBL108221146880568BindingDB-show
CHEMBL108229646890592BindingDB-show
CHEMBL108316246235428BindingDB-show
CHEMBL108610546890166BindingDB-show
CHEMBL109187416718567BindingDB-show
CHEMBL109823046222048BindingDB-show
CHEMBL11395610907460BindingDB-show
CHEMBL11646311005810BindingDB-show
CHEMBL11673511113605BindingDB-show
CHEMBL117275446912441BindingDB-show
CHEMBL117277546912442BindingDB-show
CHEMBL11753711730467BindingDB-show
CHEMBL121015444469677BindingDB-show
CHEMBL124333546929551BindingDB-show
CHEMBL124336646929553BindingDB-show
CHEMBL124336746929554BindingDB-show
CHEMBL124339446929647BindingDB-show
CHEMBL124339546929648BindingDB-show
CHEMBL1364413048195BindingDB-show
CHEMBL1364513048194BindingDB-show
CHEMBL1585959851785BindingDB-show
CHEMBL16279805944BindingDB-show
CHEMBL17923411349921BindingDB-show
CHEMBL18127811340290BindingDB-show
CHEMBL18370611282005BindingDB-show
CHEMBL18548910205121BindingDB-show
CHEMBL18709344394909BindingDB-show
CHEMBL1891189804849BindingDB-show
CHEMBL19483711539632BindingDB-show
CHEMBL2105149872676BindingDB-show
CHEMBL21335744414337BindingDB-show
CHEMBL21388616082828BindingDB-show
CHEMBL21431116082831BindingDB-show
CHEMBL21431216082833BindingDB-show
CHEMBL22141311293983BindingDB-show
CHEMBL22141411238716BindingDB-show
CHEMBL22146211166846BindingDB-show
CHEMBL22146311338659BindingDB-show
CHEMBL22166411189839BindingDB-show
CHEMBL22167810003369BindingDB-show
CHEMBL22171611351801BindingDB-show
CHEMBL22171811443495BindingDB-show
CHEMBL22173010279311BindingDB-show
CHEMBL22208311329753BindingDB-show
CHEMBL22213910162727BindingDB-show
CHEMBL22214211212029BindingDB-show
CHEMBL22221411363750BindingDB-show
CHEMBL22221711430513BindingDB-show
CHEMBL22235610139591BindingDB-show
CHEMBL22237210202996BindingDB-show
CHEMBL2228539889248BindingDB-show
CHEMBL22288110204866BindingDB-show
CHEMBL22292711453538BindingDB-show
CHEMBL22298411211919BindingDB-show
CHEMBL22298510273238BindingDB-show
CHEMBL2230249889247BindingDB-show
CHEMBL2230259979651BindingDB-show
CHEMBL22383710139592BindingDB-show
CHEMBL22388211259138BindingDB-show
CHEMBL22388911487026BindingDB-show
CHEMBL22942916737207BindingDB-show
CHEMBL30382410064805BindingDB-show
CHEMBL31696844334556BindingDB-show
CHEMBL31923144334521BindingDB-show
CHEMBL32017444333987BindingDB-show
CHEMBL32132044334407BindingDB-show
CHEMBL32170944334368BindingDB-show
CHEMBL32267844334234BindingDB-show
CHEMBL32269544334265BindingDB-show
CHEMBL32351744334035BindingDB-show
CHEMBL32551611071079BindingDB-show
CHEMBL32626310885636BindingDB-show
CHEMBL36071210478188BindingDB-show
CHEMBL3607919822631BindingDB-show
CHEMBL36180510141470BindingDB-show
CHEMBL36505510434776BindingDB-show
CHEMBL37353411476077BindingDB-show
CHEMBL37405911247290BindingDB-show
CHEMBL37421810138404BindingDB-show
CHEMBL37445911785584BindingDB-show
CHEMBL37458511396873BindingDB-show
CHEMBL37467511385692BindingDB-show
CHEMBL37475411247939BindingDB-show
CHEMBL37475511202401BindingDB-show
CHEMBL37486910161929BindingDB-show
CHEMBL3752089823337BindingDB-show
CHEMBL37602511328514BindingDB-show
CHEMBL37620210226501BindingDB-show
CHEMBL38513311362693BindingDB-show
CHEMBL38531110140544BindingDB-show
CHEMBL38732511373970BindingDB-show
CHEMBL38739011329754BindingDB-show
CHEMBL3873919932752BindingDB-show
CHEMBL40214344455426BindingDB-show
CHEMBL42010844334042BindingDB-show
CHEMBL4267869802248BindingDB-show
CHEMBL43050244334036BindingDB-show
CHEMBL43751910298838BindingDB-show
CHEMBL44240010465137BindingDB-show
CHEMBL45973025107505BindingDB-show
CHEMBL47141325149521BindingDB-show
CHEMBL47244125149613BindingDB-show
CHEMBL47499111496610BindingDB-show
CHEMBL47632311697697BindingDB-show
CHEMBL47683944582678BindingDB-show
CHEMBL48249644586410BindingDB-show
CHEMBL48340023151209BindingDB-show
CHEMBL48554311973780BindingDB-show
CHEMBL48824811581337BindingDB-show
CHEMBL49063244582705BindingDB-show
CHEMBL50233925149708BindingDB-show
CHEMBL50736011539020BindingDB-show
CHEMBL51389325099115BindingDB-show
CHEMBL51421711632103BindingDB-show
CHEMBL51547244582675BindingDB-show
CHEMBL51608844582676BindingDB-show
CHEMBL56038644250288BindingDB-show
CHEMBL56583345487384BindingDB-show
CHEMBL57029644469273BindingDB-show
CHEMBL59544911957735BindingDB-show
CHEMBL59606746225253BindingDB-show
CHEMBL663889818650BindingDB-show
CHEMBL6666044307779BindingDB-show
CID 1055538310326069BindingDB-show
CID 98307419830741BindingDB-show
Cidoxepinum667477DrugBank-show
ciproxifan6422124BindingDB-show
Conessinum441082BindingDB-show
Desmethylamitriptyline4543BindingDB-show
Doxepin667468BindingDB-show
Epinastine3241DrugBank-show
Epinastine3241SuperTarget-show
FAMOTIDINE5353622BindingDB-show
Gastrodomina3325DrugBank-show
Gastrodomina5702160DrugBank-show
Gastrodomina3325SuperTargetPMID 011180002show
Gastrodomina5702160SuperTargetPMID 011180002show
histamine774BindingDB-show
Histamine biphosphate65513DrugBank-show
HMS502K0644269055BindingDB-show
Immepip3035842BindingDB-show
Lafutidine5282136SuperTarget2 PMIDsshow
Methylaminopropyliminodibenzyl2995BindingDB-show
Mianserin hydrochloride68551BindingDB-show
Mianserin Monohydrochloride4184BindingDB-show
Monochlorimipramine2801BindingDB-show
NITD60944469321BindingDB-show
Nizatidine3033637DrugBank-show
Nizatidine3033637SuperTargetPMID 009990656show
Norchlorimipramine3696BindingDB-show
Peakdale1_0015363676358BindingDB-show
Ranitidine Bismutrex3033887SuperTarget2 PMIDsshow
Ranitidine hydrochloride3001055BindingDB-show
Ranitidine hydrochloride3001055DrugBank-show
Ranitidine hydrochloride3001055SuperTarget2 PMIDsshow
ROXATIDINE91276SuperTargetPMID 10462360show
SMR0001180403201696BindingDB-show
Thioperamide3035905BindingDB-show
UR-AK2425149335BindingDB-show
Vilazodone6918314BindingDB-show
[2-(3H-imidazol-4-yl)cyclopropyl]methanamine11116130BindingDB-show
[2-(3H-imidazol-4-yl)cyclopropyl]methanamine10942498BindingDB-show
[2-(3H-imidazol-4-yl)cyclopropyl]methanamine11126319BindingDB-show
[2-(3H-imidazol-4-yl)cyclopropyl]methanamine11094685BindingDB-show
Synonyms:
Gastric receptor I
H2R
Histamine H2 receptor
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q7Z5R9_HUMAN90.490.4
Q8IXH9_HUMAN48.233.6
ADRB2_HUMAN47.128.6
DRD1_HUMAN46.729.9
Q712M9_HUMAN46.431.9
Q684M0_HUMAN46.132.6
TAAR1_HUMAN45.528.4
Q546Q1_HUMAN45.131.5
5HT4R_HUMAN45.131.5
ADRB3_HUMAN45.129.7
DRD5_HUMAN44.429.4
AA1R_HUMAN44.427
Q3U4C5_MOUSE44.428
AA3R_MOUSE44.328.3
AA3R_RAT44.328.6
Q4PKD9_RAT4428.4
AA2BR_HUMAN4327.3
AA3R_HUMAN42.926.4
B1WBR3_RAT42.627
5HT6R_HUMAN41.626.7
Q9P2Q4_HUMAN40.926.4
SSR2_HUMAN40.923.6
5HT1F_HUMAN40.926.4
Q4VBL8_HUMAN40.721.6
MTR1B_HUMAN40.521.5
BKRB2_HUMAN40.523.9
AGTR1_HUMAN40.222.1
Q53YY0_HUMAN40.222.1
GPR18_HUMAN40.118.8
Q8TBK4_HUMAN40.120.9
Protein-Protein Interactions:
Uniprot nameSource
GASP2_HUMANPMID 15086532