Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Target Details

add
Name:Tyrosine-protein kinase HCK
Uniprot name:HCK_HUMAN
Accession Numbers:B4DQB6 P08631 Q29RX1 Q2VPE2 Q504R5 Q5T7K1 Q5T7K2 Q96CC0 Q9H5Y5 Q9NUA4 Q9UMJ5
EC-Number:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1AD5 1BU1 1QCF 2C0I 2C0O 2C0T 2HCK 2HK5 2OI3 2OJ2 3HCK 4HCK 5HCK
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1BM9547983BindingDB-show
2-Quinolinamine11379BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
5,6-Diphenylfuro[2,3-d]pyrimidin-4-amine290208BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Bosutinib5328940BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL107562815949620BindingDB-show
CHEMBL107619315948947BindingDB-show
CHEMBL107619446879439BindingDB-show
CHEMBL107619546879440BindingDB-show
CHEMBL107619646879441BindingDB-show
CHEMBL107619746879442BindingDB-show
CHEMBL107619846879443BindingDB-show
CHEMBL107619946220496BindingDB-show
CHEMBL107620046879444BindingDB-show
CHEMBL107620146879445BindingDB-show
CHEMBL107620246879446BindingDB-show
CHEMBL107620346879448BindingDB-show
CHEMBL107643215948949BindingDB-show
CHEMBL107643315949524BindingDB-show
CHEMBL107643615949523BindingDB-show
CHEMBL107643715949048BindingDB-show
CHEMBL107646546880067BindingDB-show
CHEMBL107646646880068BindingDB-show
CHEMBL107646815949975BindingDB-show
CHEMBL107646946880069BindingDB-show
CHEMBL107647015950141BindingDB-show
CHEMBL107647146880070BindingDB-show
CHEMBL107647246880071BindingDB-show
CHEMBL107647346880072BindingDB-show
CHEMBL107647415949890BindingDB-show
CHEMBL107647546880073BindingDB-show
CHEMBL107647615949888BindingDB-show
CHEMBL107647715949974BindingDB-show
CHEMBL107647815949976BindingDB-show
CHEMBL107648046880098BindingDB-show
CHEMBL107653346880214BindingDB-show
CHEMBL107942215949522BindingDB-show
CHEMBL107942446879438BindingDB-show
CHEMBL107994515950224BindingDB-show
CHEMBL107994646879907BindingDB-show
CHEMBL108029446879447BindingDB-show
CHEMBL108029915949521BindingDB-show
CHEMBL108047546879908BindingDB-show
CHEMBL108093046880216BindingDB-show
CHEMBL108099445375865BindingDB-show
CHEMBL108099545375866BindingDB-show
CHEMBL108109046880213BindingDB-show
CHEMBL108143646880215BindingDB-show
CHEMBL108240346891227BindingDB-show
CHEMBL108240446891228BindingDB-show
CHEMBL108269346891148BindingDB-show
CHEMBL108295824856408BindingDB-show
CHEMBL108295946891275BindingDB-show
CHEMBL108300146891080BindingDB-show
CHEMBL108302246891185BindingDB-show
CHEMBL108302311188787BindingDB-show
CHEMBL108309111574885BindingDB-show
CHEMBL108309211661290BindingDB-show
CHEMBL108334446891226BindingDB-show
CHEMBL108364446871756BindingDB-show
CHEMBL108402846891025BindingDB-show
CHEMBL108423324857629BindingDB-show
CHEMBL108423446891147BindingDB-show
CHEMBL108430246891026BindingDB-show
CHEMBL108497446890918BindingDB-show
CHEMBL108506146891024BindingDB-show
CHEMBL108524046890969BindingDB-show
CHEMBL108531646890968BindingDB-show
CHEMBL108531746890970BindingDB-show
CHEMBL108551124762205BindingDB-show
CHEMBL108551246891082BindingDB-show
CHEMBL108556446890971BindingDB-show
CHEMBL108573346891081BindingDB-show
CHEMBL108599546891184BindingDB-show
CHEMBL108599624856498BindingDB-show
CHEMBL108673046880013BindingDB-show
CHEMBL108673115949617BindingDB-show
CHEMBL108686015949619BindingDB-show
CHEMBL108700246880099BindingDB-show
CHEMBL108712746880100BindingDB-show
CHEMBL108712846880101BindingDB-show
CHEMBL108751315949621BindingDB-show
CHEMBL108752415950311BindingDB-show
CHEMBL108763646880066BindingDB-show
CHEMBL108763815949889BindingDB-show
CHEMBL108764946880135BindingDB-show
CHEMBL108765046880136BindingDB-show
CHEMBL108802746880133BindingDB-show
CHEMBL108802846880134BindingDB-show
CHEMBL108815315949618BindingDB-show
CHEMBL108842915949525BindingDB-show
CHEMBL109275444541014BindingDB-show
CHEMBL109562644605035BindingDB-show
CHEMBL109562744605037BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL1315779927718BindingDB-show
CHEMBL21185244414624BindingDB-show
CHEMBL21335611974316BindingDB-show
CHEMBL21374544414581BindingDB-show
CHEMBL22397111590078BindingDB-show
CHEMBL23193044432306BindingDB-show
CHEMBL23212518450829BindingDB-show
CHEMBL23212618451044BindingDB-show
CHEMBL23212718451029BindingDB-show
CHEMBL23233418450843BindingDB-show
CHEMBL23233544432304BindingDB-show
CHEMBL23254218451036BindingDB-show
CHEMBL23258844432305BindingDB-show
CHEMBL23273118451049BindingDB-show
CHEMBL23292718451394BindingDB-show
CHEMBL23354018451023BindingDB-show
CHEMBL23395811238420BindingDB-show
CHEMBL23396518450934BindingDB-show
CHEMBL24537716747696BindingDB-show
CHEMBL24576944440254BindingDB-show
CHEMBL24596844440256BindingDB-show
CHEMBL24616644440259BindingDB-show
CHEMBL36462311153014BindingDB-show
CHEMBL37951716043219BindingDB-show
CHEMBL39015616220354BindingDB-show
CHEMBL39104418451204BindingDB-show
CHEMBL39124744432309BindingDB-show
CHEMBL39290418450830BindingDB-show
CHEMBL39542744440261BindingDB-show
CHEMBL39543318451030BindingDB-show
CHEMBL39566218451020BindingDB-show
CHEMBL39566318451119BindingDB-show
CHEMBL39566418451024BindingDB-show
CHEMBL39566511753519BindingDB-show
CHEMBL39635944432307BindingDB-show
CHEMBL39714318451225BindingDB-show
CHEMBL41348618451102BindingDB-show
CHEMBL47781724766030BindingDB-show
CHEMBL47983544570884BindingDB-show
CHEMBL56907845486342BindingDB-show
CHIR-26511656518BindingDB-show
CID 98443209844320BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
DFP-4AB44513789BindingDB-show
DFP-4APF44513788BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
JAK Inhibitor I5494425BindingDB-show
L2G9549184BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
nchembio.117-comp91400DrugBank-show
Pazopanib10113978BindingDB-show
Pelitinib6445562BindingDB-show
Phosphonotyrosine30819DrugBank-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Xanthaurine5280343DrugBank-show
ZINC017968531583275BindingDB-show
Synonyms:
Hemopoietic cell kinase
p59-HCK/p60-HCK
Tyrosine-protein kinase HCK
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
LCK_HUMAN75.362.8
SRC_RAT71.455.2
SRC_HUMAN71.155.3
FYN_HUMAN69.755.5
YES_HUMAN67.755.4
SRC_RSVSE65.551.2
CSK_HUMAN47.231.8
BTK_HUMAN43.628
ITK_HUMAN42.227
ZAP70_HUMAN37.924.5
Q9Y6B5_HUMAN3620.2
KSYK_HUMAN35.223.1
ACV1B_HUMAN3420.3
PAK1_CAEEL33.518.9
FGFR4_HUMAN33.423.3
PYRD_RAT32.416.9
T23O_HUMAN32.318.8
OTSA_ECOLI3217.7
PHYB_ASPAW3217.9
GSHB_YEAST3218.4
ACVR1_HUMAN31.619.6
KPEL_DROME31.619.4
NTRK1_HUMAN31.519.7
KPCA_BOVIN31.418.2
ACVL1_HUMAN31.418.9
Q99052_MOUSE31.119.6
Q9KWT5_SPHSX31.117.8
PHOSP_MEASE31.118.8
KPCB_BOVIN30.717.4
DOPO_RAT30.617.9
Protein-Protein Interactions: