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Target Details

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Name:Metabotropic glutamate receptor 5
Uniprot name:GRM5_RAT
Accession Numbers:P31424
EC-Number:-
Organism:Rat
Rattus norvegicus
PDB IDs:1DDV
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(2R)-2-amino-4-(4-oxo-1,2,5-thiadiazol-3-yl)butanoic Acid9837114BindingDB-show
(2R)-2-amino-4-(4-oxo-1,2,5-thiadiazol-3-yl)butanoic Acid10465478BindingDB-show
(3-Chlorophenyl)(1-methyl-2-pyrrolidinylidene)urea9554216BindingDB-show
(3-ethyl-2-methyl-quinolin-6-yl)-(4-methoxycyclohexyl)methanone9948645BindingDB-show
1459850214598502BindingDB-show
2-methyl-4-(2-phenylethynyl)-1,3-thiazole10921526BindingDB-show
3,4-dichloro-N-[3-[(3-chlorobenzoyl)amino]phenyl]benzamide1364673BindingDB-show
3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-(4-fluoro-phenyl)-benzamide1255868BindingDB-show
3-chloro-N-(3-fluorophenyl)benzamide705916BindingDB-show
3-iodo-N-(6-methylpyridin-2-yl)benzamide3410100BindingDB-show
3-methyl-N-(6-methylpyridin-2-yl)benzamide966005BindingDB-show
4-Anilidoquinazoline deriv. 12a5328819BindingDB-show
5-(2-phenylethynyl)pyrimidine4074142BindingDB-show
5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]-2-pyridin-3-yl-pyridine10039170BindingDB-show
AC1LEZDP720466BindingDB-show
AC1LLNOK1087458BindingDB-show
AC1MQ3JU3445477BindingDB-show
AC1ND7MS4545574BindingDB-show
AC1NHGF04789737BindingDB-show
ADX-4727311383075BindingDB-show
Ambcb400341316731744BindingDB-show
Ambcb530726224159834BindingDB-show
BAS 006498511142605BindingDB-show
BAS 022769535766222BindingDB-show
BAS 022769555766223BindingDB-show
BAS 022769575766225BindingDB-show
BAS 022769855766228BindingDB-show
BAS 03754851709498BindingDB-show
BAS 074378783156573BindingDB-show
CDPPB11245456BindingDB-show
CHEBI:401395310984BindingDB-show
CHEBI:51942811323495BindingDB-show
CHEMBL10345221636918BindingDB-show
CHEMBL107562611056756BindingDB-show
CHEMBL107570717358850BindingDB-show
CHEMBL107624045375909BindingDB-show
CHEMBL107630146879732BindingDB-show
CHEMBL107631446879771BindingDB-show
CHEMBL107631613059458BindingDB-show
CHEMBL107632946879814BindingDB-show
CHEMBL107633345375910BindingDB-show
CHEMBL107634946879870BindingDB-show
CHEMBL107640846879966BindingDB-show
CHEMBL107648338397232BindingDB-show
CHEMBL107649846880146BindingDB-show
CHEMBL107937521002513BindingDB-show
CHEMBL107940346879869BindingDB-show
CHEMBL107940446879871BindingDB-show
CHEMBL107959821847810BindingDB-show
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CPCCOEt6324610BindingDB-show
CPPHA cpd9931205BindingDB-show
D-Glutaminsaeure23327BindingDB-show
Dcg-IV5310979BindingDB-show
Fenobam162834BindingDB-show
Hexanedioic acid92136BindingDB-show
L-AP4179394BindingDB-show
L-CCG-15310956BindingDB-show
LY-3414959819927BindingDB-show
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mGluR5 Antagonist, MTEP9794218BindingDB-show
MLS000038237657896BindingDB-show
MLS00215300011574130BindingDB-show
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MPEP3025961BindingDB-show
N-(2,5-diphenylpyrazol-3-yl)benzamide4156919BindingDB-show
N-(2-phenylimidazo[1,2-a]pyridin-3-yl)benzamide748028BindingDB-show
N-(4-Methyl-thiazol-2-yl)-benzamide695178BindingDB-show
N-(6-methyl-2-pyridinyl)benzamide293096BindingDB-show
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NCGC00024946-016604795BindingDB-show
NCGC00025040-016604828BindingDB-show
NSC288015324083BindingDB-show
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Oprea1_50853817385733BindingDB-show
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SMR0000170003260619BindingDB-show
SMR000105597744275BindingDB-show
SMR0001144931069776BindingDB-show
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STK138963960689BindingDB-show
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STK259299960855BindingDB-show
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STK3875255752613BindingDB-show
STK3933165159723BindingDB-show
Tocris-02856603885BindingDB-show
Tocris-11136604820BindingDB-show
trans-ACPD104766BindingDB-show
trans-ACPD104766PROMISCUOUSPMID 9603209show
ZINC00122234720633BindingDB-show
ZINC00122236720635BindingDB-show
ZINC00140100728938BindingDB-show
ZINC001709842892734BindingDB-show
ZINC00361715835261BindingDB-show
ZINC00438675871987BindingDB-show
ZINC00477397899301BindingDB-show
ZINC009493651187422BindingDB-show
ZINC011881591350348BindingDB-show
ZINC011943871354507BindingDB-show
ZINC011948911354796BindingDB-show
ZINC012165151369981BindingDB-show
ZINC012166101370058BindingDB-show
ZINC026477532110831BindingDB-show
ZINC049968885766229BindingDB-show
ZINC056036766024345BindingDB-show
Synonyms:
Metabotropic glutamate receptor 5
mGluR5
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
GRM5_MOUSE99.399
GRM5_HUMAN96.195.2
GRM1_RAT71.658.8
GRM1_HUMAN71.459.6
GRM3_HUMAN43.931.1
GRM2_HUMAN43.632.2
GRM7_HUMAN43.329.9
GRM4_HUMAN4330
GRM8_HUMAN42.230
CASR_HUMAN4125.5
GRID2_HUMAN32.418.1
FAK1_HUMAN30.617.3
TS1R2_HUMAN30.617.9
CY41_TRYBB30.416.3
FAK1_MOUSE29.917.4
TS1R3_HUMAN29.917.7
Q8NHA5_HUMAN29.616.8
Q9SAZ6_MAIZE29.616.5
GABR2_HUMAN29.417
XDH_HUMAN29.417.8
INVA_YERPS29.116
GABR1_HUMAN28.716.2
A2MG_HUMAN28.515
Q9UPF9_HUMAN28.416.7
OGA_CLOPE28.316.9
Q84KR7_MAIZE28.316.9
Q53EM0_HUMAN28.216.1
Q8IW08_HUMAN28.216.1
Q5SUJ9_HUMAN28.216.1
Q59HG8_HUMAN28.216.1
Protein-Protein Interactions:
No data available