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Target Details

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Name:Metabotropic glutamate receptor 5
Uniprot name:GRM5_HUMAN
Accession Numbers:P41594
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(1R,2S,5R,6R)-2-amino-4-thiabicyclo[3.1.0]hexane-2,6-dicarboxylic Acid10198133BindingDB-show
(3-Chlorophenyl)(1-methyl-2-pyrrolidinylidene)urea9554216BindingDB-show
(S)-3,5-Dihydroxyphenylglycine443586BindingDB-show
1459850214598502BindingDB-show
2-(3-phenylmethoxyphenyl)isoindole-1,3-dione3361967BindingDB-show
2-acetamido-N-(3-chlorophenyl)benzamide3354176BindingDB-show
2-amino-3-(4-butyl-3-oxo-1,2-oxazol-5-yl)propanoic Acid10263168BindingDB-show
2-aminobicyclo[2.1.1]hexane-2,6-dicarboxylic Acid10465017BindingDB-show
2-aminobicyclo[2.1.1]hexane-2,6-dicarboxylic Acid10775369BindingDB-show
2-methyl-4-(2-phenylethynyl)-1,3-thiazole10921526BindingDB-show
3,5-Dhpg108001BindingDB-show
3-iodo-N-(6-methylpyridin-2-yl)benzamide3410100BindingDB-show
3-methyl-N-(6-methylpyridin-2-yl)benzamide966005BindingDB-show
4-bromo-N-(6-methylpyridin-2-yl)benzamide720143BindingDB-show
4-carboxyphenylglycine5115BindingDB-show
4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid5311261BindingDB-show
4-[(S)-amino-carboxy-methyl]cubane-1-carboxylic Acid10198359BindingDB-show
5-Phosphono-D-norvaline135342BindingDB-show
5-Phosphononorvaline1216BindingDB-show
5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]-2-pyridin-3-yl-pyridine10039170BindingDB-show
A1952/0082066623968BindingDB-show
AC1LS1KG1431783BindingDB-show
AC1LSLVE1441195BindingDB-show
AC1LSLVW1441201BindingDB-show
AC1LSLVZ1441202BindingDB-show
AC1LSLWH1441208BindingDB-show
AC1LT0301447967BindingDB-show
AC1MBZ392733519BindingDB-show
AC1MHU313011435BindingDB-show
AC1MXUHM3796302BindingDB-show
AC1N11KO3972752BindingDB-show
AC1N35GI4107180BindingDB-show
AC1ND7MS4545574BindingDB-show
AC1NG5HO4694355BindingDB-show
AC1O7H0M6604893BindingDB-show
AH-262/36083015699222BindingDB-show
AIDA2071BindingDB-show
AK-918/127870934195639BindingDB-show
AK-918/127870975102443BindingDB-show
AK-918/127871034301600BindingDB-show
alpha-Mcpg1222BindingDB-show
Amino(3-hydroxyphenyl)acetic acid1217BindingDB-show
ASN 048929981447824BindingDB-show
BAS 006498511142605BindingDB-show
calcium acetylhomotaurinate71158DrugBank-show
CBPG5311040BindingDB-show
CDPPB11245456BindingDB-show
CHEBI:10448044322702BindingDB-show
CHEBI:24371844322656BindingDB-show
CHEBI:29531910354477BindingDB-show
CHEBI:401395310984BindingDB-show
CHEBI:45816244416123BindingDB-show
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D-Glutaminsaeure23327BindingDB-show
Digensaeure10255BindingDB-show
Eglumegad213056BindingDB-show
Fenobam162834BindingDB-show
FTIDC11245287BindingDB-show
Glutamicol33032BindingDB-show
Glutaminsaeure611BindingDB-show
Hexanedioic acid92136BindingDB-show
Ibotenic acid1233BindingDB-show
L-AP4179394BindingDB-show
L-CCG-15310956BindingDB-show
L-Homocysteic acid177491BindingDB-show
Lopac-A-2546603702BindingDB-show
LY-3414959819927BindingDB-show
LY3074526324634BindingDB-show
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M-MPEP5311462BindingDB-show
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MLS000038237657896BindingDB-show
MLS00350908710081842BindingDB-show
MPEP3025961BindingDB-show
N-(2,5-diphenylpyrazol-3-yl)benzamide4156919BindingDB-show
NCGC00024946-016604795BindingDB-show
NSC379649342595BindingDB-show
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SMR000105597744275BindingDB-show
SMR0001144931069776BindingDB-show
ST004271692972BindingDB-show
ST0100071284324BindingDB-show
ST031112603306BindingDB-show
ST090431585532BindingDB-show
STK2349604287026BindingDB-show
STK2692025110066BindingDB-show
Tocris-01866604704BindingDB-show
Tocris-03235311459BindingDB-show
trans-ACPD104766BindingDB-show
XILOBAM9570595BindingDB-show
ZINC000746102725933BindingDB-show
ZINC00477397899301BindingDB-show
ZINC00509317921213BindingDB-show
ZINC010372952818849BindingDB-show
ZINC011708921336785BindingDB-show
ZINC038791052837010BindingDB-show
Synonyms:
Metabotropic glutamate receptor 5
mGluR5
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
GRM5_MOUSE96.395.5
GRM5_RAT96.195.2
GRM1_HUMAN71.259.3
GRM1_RAT70.758.5
GRM3_HUMAN43.831.2
GRM2_HUMAN43.432.1
GRM7_HUMAN43.229.7
GRM4_HUMAN42.829.8
GRM8_HUMAN42.129.9
CASR_HUMAN41.224.8
ACRB_ECOLI31.317.7
GABR2_HUMAN30.217.8
TS1R2_HUMAN3017.8
FAK1_HUMAN29.717.2
TS1R3_HUMAN29.617.7
GRIK4_HUMAN29.516.9
PUTA_ECOLI29.517.4
Q8NHA5_HUMAN29.216.6
ITAM_HUMAN29.117
FAK1_MOUSE29.117.3
ANPRA_HUMAN2916.5
Q9SAZ6_MAIZE28.916.4
ANPRA_RAT28.416.8
INVA_YERPS28.115.8
GABR1_HUMAN27.915.4
GRID1_HUMAN27.815.7
GRID2_HUMAN27.715.2
XDH_BOVIN27.616.9
GRIK5_HUMAN27.615.5
SYJ1_SCHPO27.516.7
Protein-Protein Interactions: