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Target Details

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Name:Metabotropic glutamate receptor 1
Uniprot name:GRM1_HUMAN
Accession Numbers:B9EG79 Q13255 Q13256 Q14757 Q14758 Q5VTF7 Q5VTF8 Q9NU10 Q9UGS9 Q9UGT0
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(+)-alpha-Methyl-4-carboxyphenylglycine446355BindingDB-show
(1R,2S,5R,6R)-2-amino-4-thiabicyclo[3.1.0]hexane-2,6-dicarboxylic Acid10198133BindingDB-show
(1r,3r)-1-aminocyclopentane-1,3-dicarboxylic acid231345BindingDB-show
(1R,3S)-1-Aminocyclopentane-1,3-dicarboxylic acid73537BindingDB-show
(1S,3R)-1-amino-3-(carboxymethyl)cyclopentane-1-carboxylic Acid10012681BindingDB-show
(2S,3S,4S)-2-amino-3,4-dihydroxy-pentanedioic Acid10442268BindingDB-show
(3-ethyl-2-fluoro-quinolin-6-yl)-(4-methoxycyclohexyl)methanone11174504BindingDB-show
(S)-3,5-Dihydroxyphenylglycine443586BindingDB-show
(S)-AMPA158397BindingDB-show
1459850214598502BindingDB-show
2-amino-3-(4-butyl-3-oxo-1,2-oxazol-5-yl)propanoic Acid10263168BindingDB-show
2-aminobicyclo[2.1.1]hexane-2,6-dicarboxylic Acid10465017BindingDB-show
2-aminobicyclo[2.1.1]hexane-2,6-dicarboxylic Acid10775369BindingDB-show
2-Aminopimelate101122BindingDB-show
2-aminosuberic Acid77937BindingDB-show
2-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,511948707BindingDB-show
2-[4-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-tri11676174BindingDB-show
3,5-Dhpg108001BindingDB-show
4-carboxyphenylglycine5115BindingDB-show
4-Chpgly1297BindingDB-show
4-fluoro-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)benzamide2660431BindingDB-show
4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid5311261BindingDB-show
4-[(S)-amino-carboxy-methyl]cubane-1-carboxylic Acid10198359BindingDB-show
5-Phosphono-D-norvaline135342BindingDB-show
5-Phosphononorvaline1216BindingDB-show
71366-32-02733518BindingDB-show
AC1MBZ392733519BindingDB-show
AC1MBZ3L2733524BindingDB-show
AC1MMXWB3246152BindingDB-show
AC1N11KO3972752BindingDB-show
AC1N6KQF4236420BindingDB-show
AC1ND7MS4545574BindingDB-show
AC1NG5HO4694355BindingDB-show
AC1NG5HR4694356BindingDB-show
AC1NSKOL5311460BindingDB-show
AH-262/36083015699222BindingDB-show
AIDA2071BindingDB-show
alpha-Mcpg1222BindingDB-show
Amaa acid173564BindingDB-show
Amino(3-hydroxyphenyl)acetic acid1217BindingDB-show
ampa6604707BindingDB-show
calcium acetylhomotaurinate71158DrugBank-show
CBPG5311040BindingDB-show
CHEBI:10448044322702BindingDB-show
CHEBI:24371844322656BindingDB-show
CHEBI:401395310984BindingDB-show
CHEBI:48031439282BindingDB-show
CHEMBL109024746886135BindingDB-show
CHEMBL109227546886136BindingDB-show
CHEMBL109227646886137BindingDB-show
CHEMBL109227746886138BindingDB-show
CHEMBL109356046866191BindingDB-show
CHEMBL109356146886169BindingDB-show
CHEMBL109368446886118BindingDB-show
CHEMBL109386846886139BindingDB-show
CHEMBL109386946886140BindingDB-show
CHEMBL109390146866192BindingDB-show
CHEMBL109390246886119BindingDB-show
CHEMBL109398746886120BindingDB-show
CHEMBL11144110609381BindingDB-show
CHEMBL125350146927956BindingDB-show
CHEMBL125350252944782BindingDB-show
CHEMBL12660811820180BindingDB-show
CHEMBL126912549788729BindingDB-show
CHEMBL126912649788731BindingDB-show
CHEMBL126912749788806BindingDB-show
CHEMBL127062152941697BindingDB-show
CHEMBL127071849788655BindingDB-show
CHEMBL127071949788727BindingDB-show
CHEMBL15357222268047BindingDB-show
CHEMBL16582810018131BindingDB-show
CHEMBL17421611450605BindingDB-show
CHEMBL17421844387711BindingDB-show
CHEMBL17438211483517BindingDB-show
CHEMBL17537744387697BindingDB-show
CHEMBL17546311232687BindingDB-show
CHEMBL17564310245890BindingDB-show
CHEMBL17569911324832BindingDB-show
CHEMBL17606811382171BindingDB-show
CHEMBL17627911255377BindingDB-show
CHEMBL17704311177701BindingDB-show
CHEMBL17704411347844BindingDB-show
CHEMBL17751911232871BindingDB-show
CHEMBL17758511403753BindingDB-show
CHEMBL17758610085578BindingDB-show
CHEMBL17773611439265BindingDB-show
CHEMBL17796244387705BindingDB-show
CHEMBL17827011383509BindingDB-show
CHEMBL17827111461116BindingDB-show
CHEMBL17869011483690BindingDB-show
CHEMBL17874111209923BindingDB-show
CHEMBL17874211185961BindingDB-show
CHEMBL21201811299421BindingDB-show
CHEMBL21310211414108BindingDB-show
CHEMBL22339911515957BindingDB-show
CHEMBL22354311639176BindingDB-show
CHEMBL22381911594849BindingDB-show
CHEMBL22386811681681BindingDB-show
CHEMBL22386911515548BindingDB-show
CHEMBL22408411717278BindingDB-show
CHEMBL22408811660540BindingDB-show
CHEMBL22413511565466BindingDB-show
CHEMBL22420011493585BindingDB-show
CHEMBL22431511493897BindingDB-show
CHEMBL22432211696595BindingDB-show
CHEMBL22435611688880BindingDB-show
CHEMBL22437511560185BindingDB-show
CHEMBL22437711652895BindingDB-show
CHEMBL22461711609353BindingDB-show
CHEMBL22467211515679BindingDB-show
CHEMBL22467311501465BindingDB-show
CHEMBL22479811566478BindingDB-show
CHEMBL22489811661106BindingDB-show
CHEMBL22503211537456BindingDB-show
CHEMBL22512411667270BindingDB-show
CHEMBL22512511581985BindingDB-show
CHEMBL22512611682046BindingDB-show
CHEMBL22520111530971BindingDB-show
CHEMBL22543811537814BindingDB-show
CHEMBL22543944421618BindingDB-show
CHEMBL22559011574901BindingDB-show
CHEMBL22942916737207BindingDB-show
CHEMBL23085217758444BindingDB-show
CHEMBL23094917758555BindingDB-show
CHEMBL23095017758449BindingDB-show
CHEMBL23115717758443BindingDB-show
CHEMBL23576716659798BindingDB-show
CHEMBL23597516659966BindingDB-show
CHEMBL23597716659968BindingDB-show
CHEMBL23617723657393BindingDB-show
CHEMBL23617816659804BindingDB-show
CHEMBL23618016659803BindingDB-show
CHEMBL23699416659801BindingDB-show
CHEMBL23807716659643BindingDB-show
CHEMBL23807916659646BindingDB-show
CHEMBL23809016659964BindingDB-show
CHEMBL23826216038352BindingDB-show
CHEMBL23826316659642BindingDB-show
CHEMBL24132716659802BindingDB-show
CHEMBL24154744435349BindingDB-show
CHEMBL24599044442431BindingDB-show
CHEMBL24599144442433BindingDB-show
CHEMBL24660944442425BindingDB-show
CHEMBL24661044442427BindingDB-show
CHEMBL24661144442428BindingDB-show
CHEMBL24683944442422BindingDB-show
CHEMBL24684044442423BindingDB-show
CHEMBL24721644442435BindingDB-show
CHEMBL24805244442424BindingDB-show
CHEMBL24820915207262BindingDB-show
CHEMBL24821044442420BindingDB-show
CHEMBL24823323655076BindingDB-show
CHEMBL2543729903757BindingDB-show
CHEMBL25457344447971BindingDB-show
CHEMBL25477711716890BindingDB-show
CHEMBL28773710103891BindingDB-show
CHEMBL28778515840277BindingDB-show
CHEMBL29255344302930BindingDB-show
CHEMBL29343444302608BindingDB-show
CHEMBL29605410846649BindingDB-show
CHEMBL30033044302818BindingDB-show
CHEMBL30241110358265BindingDB-show
CHEMBL30403444302913BindingDB-show
CHEMBL30491944302856BindingDB-show
CHEMBL30540610428048BindingDB-show
CHEMBL31008544312782BindingDB-show
CHEMBL3131249815955BindingDB-show
CHEMBL31339444322843BindingDB-show
CHEMBL31371344322745BindingDB-show
CHEMBL31645144322518BindingDB-show
CHEMBL31927910456810BindingDB-show
CHEMBL31973244329031BindingDB-show
CHEMBL32468644338561BindingDB-show
CHEMBL32923610656383BindingDB-show
CHEMBL32990510036599BindingDB-show
CHEMBL32992044329032BindingDB-show
CHEMBL33009744322840BindingDB-show
CHEMBL33416010176324BindingDB-show
CHEMBL35354711347669BindingDB-show
CHEMBL35988311474450BindingDB-show
CHEMBL36072811232604BindingDB-show
CHEMBL36644844387723BindingDB-show
CHEMBL36722711485531BindingDB-show
CHEMBL36945910470232BindingDB-show
CHEMBL37130111543205BindingDB-show
CHEMBL37413511682866BindingDB-show
CHEMBL37416711552320BindingDB-show
CHEMBL37418011702918BindingDB-show
CHEMBL37481511681575BindingDB-show
CHEMBL37543911501188BindingDB-show
CHEMBL37637211582178BindingDB-show
CHEMBL38533611530404BindingDB-show
CHEMBL38577611666576BindingDB-show
CHEMBL38640811537767BindingDB-show
CHEMBL38656511559235BindingDB-show
CHEMBL38693511631279BindingDB-show
CHEMBL38768711588590BindingDB-show
CHEMBL38797611654379BindingDB-show
CHEMBL38882711681680BindingDB-show
CHEMBL38955517758554BindingDB-show
CHEMBL38955617758445BindingDB-show
CHEMBL38955717758556BindingDB-show
CHEMBL38955817758450BindingDB-show
CHEMBL38965511695588BindingDB-show
CHEMBL38987011717319BindingDB-show
CHEMBL38989711695769BindingDB-show
CHEMBL38991811703031BindingDB-show
CHEMBL39039111639210BindingDB-show
CHEMBL3921522708855BindingDB-show
CHEMBL39216416659799BindingDB-show
CHEMBL39370516659645BindingDB-show
CHEMBL39392216659967BindingDB-show
CHEMBL39392316659805BindingDB-show
CHEMBL39491416659963BindingDB-show
CHEMBL39894444442421BindingDB-show
CHEMBL39912744442432BindingDB-show
CHEMBL39912844442434BindingDB-show
CHEMBL39930944442430BindingDB-show
CHEMBL39946044442436BindingDB-show
CHEMBL40011044442426BindingDB-show
CHEMBL40030744442429BindingDB-show
CHEMBL4012310359073BindingDB-show
CHEMBL40172144447970BindingDB-show
CHEMBL40621544302929BindingDB-show
CHEMBL4135210374869BindingDB-show
CHEMBL41846244302819BindingDB-show
CHEMBL41865044302931BindingDB-show
CHEMBL42026244329029BindingDB-show
CHEMBL4214810560963BindingDB-show
CHEMBL42601811530673BindingDB-show
CHEMBL42619011660511BindingDB-show
CHEMBL42963516659647BindingDB-show
CHEMBL43977544329042BindingDB-show
CHEMBL44184411186076BindingDB-show
CHEMBL44471844569826BindingDB-show
CHEMBL44524144569861BindingDB-show
CHEMBL44888544569860BindingDB-show
CHEMBL45002544569827BindingDB-show
CHEMBL45261844588463BindingDB-show
CHEMBL45324944588461BindingDB-show
CHEMBL45619611695894BindingDB-show
CHEMBL45682344588464BindingDB-show
CHEMBL45702611674352BindingDB-show
CHEMBL45787244588460BindingDB-show
CHEMBL45787344588462BindingDB-show
CHEMBL46039144588386BindingDB-show
CHEMBL46082744588425BindingDB-show
CHEMBL46103344588427BindingDB-show
CHEMBL46103444588428BindingDB-show
CHEMBL46103544588429BindingDB-show
CHEMBL46167344588385BindingDB-show
CHEMBL46723444569859BindingDB-show
CHEMBL46723544569862BindingDB-show
CHEMBL46938211772954BindingDB-show
CHEMBL49688244190040BindingDB-show
CHEMBL49791710851012BindingDB-show
CHEMBL50510544190035BindingDB-show
CHEMBL50752244572113BindingDB-show
CHEMBL51135244588426BindingDB-show
CHEMBL51135519705292BindingDB-show
CHEMBL55607025067015BindingDB-show
CHEMBL56593445486764BindingDB-show
CHEMBL56594345484935BindingDB-show
CHEMBL56594845484880BindingDB-show
CHEMBL56597245484889BindingDB-show
CHEMBL56637416660140BindingDB-show
CHEMBL56658116660135BindingDB-show
CHEMBL56758445484973BindingDB-show
CHEMBL56766745486748BindingDB-show
CHEMBL56766816661728BindingDB-show
CHEMBL56767316661729BindingDB-show
CHEMBL56824145484872BindingDB-show
CHEMBL56831716661409BindingDB-show
CHEMBL56832145486781BindingDB-show
CHEMBL56844315985249BindingDB-show
CHEMBL56844945484871BindingDB-show
CHEMBL56845045484928BindingDB-show
CHEMBL56845145484929BindingDB-show
CHEMBL56864845484920BindingDB-show
CHEMBL56899116038338BindingDB-show
CHEMBL56927016660294BindingDB-show
CHEMBL57168745486755BindingDB-show
CHEMBL57213516661408BindingDB-show
CHEMBL57214445486758BindingDB-show
CHEMBL57219845486754BindingDB-show
CHEMBL57604345486799BindingDB-show
CHEMBL57612116661406BindingDB-show
CHEMBL57623145484850BindingDB-show
CHEMBL57643445484905BindingDB-show
CHEMBL57663745484964BindingDB-show
CHEMBL57703516661404BindingDB-show
CHEMBL57750545486817BindingDB-show
CHEMBL57772916660467BindingDB-show
CHEMBL57783311772069BindingDB-show
CHEMBL57794345484921BindingDB-show
CHEMBL57856545484897BindingDB-show
CHEMBL57858016661726BindingDB-show
CHEMBL57899511175501BindingDB-show
CHEMBL57901145486816BindingDB-show
CHEMBL57906215985251BindingDB-show
CHEMBL57921345486747BindingDB-show
CHEMBL57922516661405BindingDB-show
CHEMBL5824722884216BindingDB-show
CHEMBL58359045484965BindingDB-show
CHEMBL58406645486778BindingDB-show
CHEMBL58447811325594BindingDB-show
CHEMBL58461045484911BindingDB-show
CHEMBL59359023725699BindingDB-show
CHEMBL5968644302687BindingDB-show
CHEMBL5983044302837BindingDB-show
CHEMBL5992044302896BindingDB-show
CHEMBL6000844302605BindingDB-show
CHEMBL6016444302686BindingDB-show
CHEMBL6023815508178BindingDB-show
CHEMBL6030244302855BindingDB-show
CHEMBL6128144302609BindingDB-show
CHEMBL6196444302932BindingDB-show
CHEMBL7215744312783BindingDB-show
CHEMBL7267644312898BindingDB-show
CHEMBL7318444312850BindingDB-show
CHEMBL7368744312607BindingDB-show
CHEMBL7452544312440BindingDB-show
CHEMBL7492444312913BindingDB-show
CHEMBL8818410012356BindingDB-show
CHEMBL8899910058694BindingDB-show
CHEMBL8900044322701BindingDB-show
CHEMBL8929344322537BindingDB-show
CHEMBL9050144322921BindingDB-show
CHEMBL921189844204BindingDB-show
CHEMBL9586844328753BindingDB-show
CHEMBL9708310241509BindingDB-show
CHEMBL9720044329033BindingDB-show
CHEMBL9757444328850BindingDB-show
CHEMBL9946244329024BindingDB-show
CID 1071479110523805BindingDB-show
CID 1071479110714791BindingDB-show
CPCCOEt6278000BindingDB-show
CPCCOEt44358757BindingDB-show
D-2-aminoadipic acid165627BindingDB-show
D-Asparaginsaeure83887BindingDB-show
D-Glutaminsaeure23327BindingDB-show
Dcg-IV115114BindingDB-show
Eglumegad213056BindingDB-show
Fenobam162834BindingDB-show
FTIDC11245287BindingDB-show
Glutamicol33032BindingDB-show
Glutamicol33032DrugBank-show
Glutaminsaeure611BindingDB-show
Hexanedioic acid92136BindingDB-show
Ibotenic acid1233BindingDB-show
JNJ-1625968511313361BindingDB-show
L-AP4179394BindingDB-show
L-CCG-15310956BindingDB-show
L-Homocysteic acid177491BindingDB-show
Lopac-A-2546603702BindingDB-show
LY-3414959819927BindingDB-show
LY-37926810197984BindingDB-show
LY3074526324634BindingDB-show
LY3673853931705BindingDB-show
LY3936755311262BindingDB-show
Methoxy-cyclohexyl Ketone11256015BindingDB-show
mGluR5 Antagonist, MTEP9794218BindingDB-show
MLS000038237657896BindingDB-show
MPEP3025961BindingDB-show
NCGC00024946-016604795BindingDB-show
Philanthotoxin 343159548BindingDB-show
Quisqualate40539BindingDB-show
SIB 17576324664BindingDB-show
SIB 18935311432BindingDB-show
SMR0000705551208332BindingDB-show
SMR000105597744275BindingDB-show
SMR0001144931069776BindingDB-show
ST004271692972BindingDB-show
ST0100071284324BindingDB-show
Tocris-01866604704BindingDB-show
Tocris-02856603885BindingDB-show
Tocris-03205311455BindingDB-show
Tocris-03235311459BindingDB-show
Tocris-03246604712BindingDB-show
trans-ACPD104766BindingDB-show
ZINC000269679926999BindingDB-show
ZINC00074342697713BindingDB-show
Synonyms:
Metabotropic glutamate receptor 1
mGluR1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
GRM1_RAT96.394.2
GRM5_RAT71.459.6
GRM5_HUMAN71.259.3
GRM5_MOUSE70.959.3
GRM3_HUMAN4531.9
GRM2_HUMAN4533.3
GRM8_HUMAN44.731.7
GRM4_HUMAN44.331.4
GRM7_HUMAN4430.7
CASR_HUMAN42.826.5
TS1R2_HUMAN31.217.8
GRID2_HUMAN30.516.7
TS1R3_HUMAN30.218.2
Q547U9_HUMAN30.116.2
NMDE1_HUMAN30.116.2
Q59EW6_HUMAN3016.4
GABR2_HUMAN29.616.6
ITA11_HUMAN29.216.8
Q8NHA5_HUMAN29.117.8
MYO3_YEAST28.916.4
Q59GY9_HUMAN28.915.5
ERBB2_HUMAN28.818.2
NOS2_BOVIN28.817.1
ANPRA_HUMAN28.616.4
PDE6A_BOVIN28.516.6
FAK1_HUMAN28.516.7
AT8A1_HUMAN28.416.3
FAK1_MOUSE28.416.2
GRID1_HUMAN28.315.3
VGFR2_HUMAN28.315.4
Protein-Protein Interactions: