Target Details

Name:	EAA4
Uniprot name:	GRIK2_HUMAN
Accession Numbers:	Q13002 Q8WWS1 Q96KS6 Q96KS7 Q96KS8
EC-Number:	-
Organism:	Homo sapiens Human
PDB IDs:	-
KEGG Pathways:	show KEGG Pathways
Drugs:	Name PubChem ID Source References Interaction (2R)-2-amino-4-cinnamyl-pentanedioic Acid 10777943 BindingDB - show (2R,4R)-2-amino-4-(3-phenylprop-2-ynyl)pentanedioic Acid 10777807 BindingDB - show (2R,4R)-2-amino-4-(3-phenylpropyl)pentanedioic Acid 10515815 BindingDB - show (2S,4R)-2-amino-4-prop-2-ynyl-pentanedioic Acid 10773867 BindingDB - show (2S,4R)-2-amino-4-prop-2-ynyl-pentanedioic Acid 10797596 BindingDB - show (2S,4R)-2-amino-4-propyl-pentanedioic Acid 11745400 BindingDB - show (2S,4R)-2-amino-4-[(Z)-but-2-enyl]pentanedioic Acid 10774436 BindingDB - show (2S,4R)-2-amino-4-[(Z)-but-2-enyl]pentanedioic Acid 10559986 BindingDB - show (2S,4R)-2-amino-4-[(Z)-pent-2-enyl]pentanedioic Acid 10632449 BindingDB - show (2S,4Z)-2-amino-4-(2-methylpropylidene)pentanedioic Acid 10330442 BindingDB - show (2S,4Z)-2-amino-4-(2-methylpropylidene)pentanedioic Acid 11820131 BindingDB - show (S)-AMPA 158397 BindingDB - show 14598502 14598502 BindingDB - show 71366-32-0 2733518 BindingDB - show AC1NG5HR 4694356 BindingDB - show AC1NR9MB 5287396 BindingDB - show ampa 1221 BindingDB - show BN1 447081 BindingDB - show CHEBI:48031 439282 BindingDB - show CHEBI:647510 44358120 BindingDB - show CHEMBL118502 10520393 BindingDB - show CHEMBL120003 10708836 BindingDB - show CHEMBL120288 10543516 BindingDB - show CHEMBL120450 10592607 BindingDB - show CHEMBL120753 10663146 BindingDB - show CHEMBL120785 10566652 BindingDB - show CHEMBL121113 10498120 BindingDB - show CHEMBL121194 10660003 BindingDB - show CHEMBL121461 10804393 BindingDB - show CHEMBL121510 10760378 BindingDB - show CHEMBL121514 10597645 BindingDB - show CHEMBL121741 10754863 BindingDB - show CHEMBL122507 10545609 BindingDB - show CHEMBL122523 10741044 BindingDB - show CHEMBL123006 10809478 BindingDB - show CHEMBL12465 22100152 BindingDB - show CHEMBL13076 10437436 BindingDB - show CHEMBL154700 9799478 BindingDB - show CHEMBL177627 10694271 BindingDB - show CHEMBL189721 11154806 BindingDB - show CHEMBL193087 11818375 BindingDB - show CHEMBL224688 9977288 BindingDB - show CHEMBL224872 11742032 BindingDB - show CHEMBL224926 10091990 BindingDB - show CHEMBL268284 22097088 BindingDB - show CHEMBL291491 10592589 BindingDB - show CHEMBL292745 10778899 BindingDB - show CHEMBL292896 10854556 BindingDB - show CHEMBL293118 10806437 BindingDB - show CHEMBL293548 10494266 BindingDB - show CHEMBL293613 22449297 BindingDB - show CHEMBL293829 10732079 BindingDB - show CHEMBL294683 10588885 BindingDB - show CHEMBL297283 44296615 BindingDB - show CHEMBL297919 44296576 BindingDB - show CHEMBL298779 44296602 BindingDB - show CHEMBL299291 44296355 BindingDB - show CHEMBL299365 44296375 BindingDB - show CHEMBL299449 44301844 BindingDB - show CHEMBL300368 10638626 BindingDB - show CHEMBL300928 44296822 BindingDB - show CHEMBL301915 10831138 BindingDB - show CHEMBL302402 10585396 BindingDB - show CHEMBL302680 10518677 BindingDB - show CHEMBL303415 22100077 BindingDB - show CHEMBL305346 10780042 BindingDB - show CHEMBL305534 44307264 BindingDB - show CHEMBL331339 10592608 BindingDB - show CHEMBL331477 10683926 BindingDB - show CHEMBL332114 10524733 BindingDB - show CHEMBL332126 10543350 BindingDB - show CHEMBL332168 10614515 BindingDB - show CHEMBL332334 10379406 BindingDB - show CHEMBL332467 10685849 BindingDB - show CHEMBL332818 10827292 BindingDB - show CHEMBL333015 10804508 BindingDB - show CHEMBL333790 10689269 BindingDB - show CHEMBL334024 10596851 BindingDB - show CHEMBL334119 10266964 BindingDB - show CHEMBL346524 10132082 BindingDB - show CHEMBL368275 10546918 BindingDB - show CHEMBL370941 11288627 BindingDB - show CHEMBL372643 11219775 BindingDB - show CHEMBL373429 16125102 BindingDB - show CHEMBL375004 16125096 BindingDB - show CHEMBL379442 11544633 BindingDB - show CHEMBL387549 10409259 BindingDB - show CHEMBL416685 22100122 BindingDB - show CHEMBL420720 44346652 BindingDB - show CHEMBL420724 10522010 BindingDB - show CHEMBL429540 44307207 BindingDB - show CHEMBL431657 10497847 BindingDB - show CHEMBL431839 10566879 BindingDB - show CHEMBL50041 44296800 BindingDB - show CHEMBL51008 10398361 BindingDB - show CHEMBL51054 44296494 BindingDB - show CHEMBL51395 44296493 BindingDB - show CHEMBL51660 10219992 BindingDB - show CHEMBL52295 15347044 BindingDB - show CHEMBL52514 15347043 BindingDB - show CHEMBL52742 10330885 BindingDB - show CHEMBL53194 44296585 BindingDB - show CHEMBL53655 44296575 BindingDB - show CHEMBL53702 44296807 BindingDB - show CHEMBL53775 44296601 BindingDB - show CHEMBL54073 44296603 BindingDB - show CHEMBL54238 44296812 BindingDB - show CHEMBL54291 18395300 BindingDB - show CHEMBL58027 10680281 BindingDB - show CHEMBL58054 10732793 BindingDB - show CHEMBL58095 15839907 BindingDB - show CHEMBL58541 10608628 BindingDB - show CHEMBL58590 9861035 BindingDB - show CHEMBL59284 10541731 BindingDB - show CHEMBL59286 10846340 BindingDB - show CHEMBL59297 10520545 BindingDB - show CHEMBL59299 10589792 BindingDB - show CHEMBL59948 10758246 BindingDB - show CHEMBL60114 11791928 BindingDB - show CHEMBL60168 10733581 BindingDB - show CHEMBL60406 10775370 BindingDB - show CHEMBL61434 10494920 BindingDB - show CHEMBL61697 10588564 BindingDB - show CHEMBL61751 10805132 BindingDB - show CHEMBL62053 10751988 BindingDB - show CHEMBL62086 9837067 BindingDB - show CHEMBL63861 9958244 BindingDB - show CHEMBL63927 44307281 BindingDB - show CHEMBL67828 9807075 BindingDB - show CID 10113274 11249042 BindingDB - show CID 10268946 11199813 BindingDB - show CID 10767237 10767237 BindingDB - show CID 10767237 10672549 BindingDB - show CID 9924171 11153198 BindingDB - show D-Glutaminsaeure 23327 BindingDB - show Digensaeure 10255 BindingDB - show Glutamicol 33032 DrugBank - show LY339434 6324635 BindingDB - show LY382884 656723 BindingDB - show nbqx 3272524 BindingDB - show nchembio756-comp2 6323174 BindingDB - show Ted-isoquinoline-3-cooh 127894 BindingDB - show threo-gamma-Methylglutamate 95883 BindingDB - show UBA 6420160 BindingDB - show UBC 6420161 BindingDB - show enlarge table
Synonyms:	EAA4 Excitatory amino acid receptor 4 GluR-6 GluR6 Glutamate receptor 6 Glutamate receptor, ionotropic kainate 2 enlarge table
Similar targets:	Uniprot name % Sequence similarity % Sequence identity GRIK2_RAT 99.6 99.1 GRIK3_HUMAN 88.3 78.3 GRIK1_HUMAN 84.1 74.2 GRIA3_HUMAN 56.8 39.3 GRIK4_HUMAN 55.7 40.1 GRIK5_HUMAN 55.6 39.6 GRIA2_RAT 54.7 37 GRIA4_HUMAN 54.7 37.8 GRIA2_HUMAN 54.6 37.4 GRIA1_HUMAN 54 36.8 Q59F93_HUMAN 53 36 GRID1_HUMAN 44.1 26.6 GRID2_HUMAN 44 26.2 Q9UPF8_HUMAN 42.6 24.5 Q5VSF5_HUMAN 42.6 24.6 NMDZ1_HUMAN 42.6 24.5 Q9UPF9_HUMAN 42.1 24.3 Q5VSF4_HUMAN 42.1 24.4 NMDZ1_RAT 41.9 24.1 Q59H41_HUMAN 41.3 23.7 Q5VSF9_HUMAN 41.1 23.8 NMD3A_HUMAN 34.2 19.1 NMD3A_RAT 33.8 18.6 GABR2_HUMAN 32.4 17.9 NMD3B_HUMAN 32 18.7 CASR_HUMAN 31.8 19 Q8IW08_HUMAN 31 16.2 Q5SUJ9_HUMAN 31 16.2 Q53EM0_HUMAN 31 16.2 RAD50_PYRFU 30.9 17.9 enlarge table
Protein-Protein Interactions:	Uniprot name Source Q8N1F0_HUMAN PMID 16102538 GRIK4_HUMAN 2 PMIDs GRIK2_HUMAN 3 PMIDs enlarge table

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