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Target Details

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Name:Glutamate receptor 1
Uniprot name:GRIA1_HUMAN
Accession Numbers:P42261 Q2NKM6
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(2S,4Z)-2-amino-4-(2-methylpropylidene)pentanedioic Acid10330442BindingDB-show
(2S,4Z)-2-amino-4-(2-methylpropylidene)pentanedioic Acid11820131BindingDB-show
(S)-AMPA158397BindingDB-show
1459850214598502BindingDB-show
1nnk447407BindingDB-show
2-AMINO-3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]-4-ISOXAZOLYL)PROPIONIC ACID5288598BindingDB-show
2-Quinoxalinecarboxylic acid, 6,7-dichloro-3,4-dihydro-3-oxo-3018579BindingDB-show
2-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,511948707BindingDB-show
2-[4-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-tri11676174BindingDB-show
3-(5-Chloro-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl)-L-Alanine44152410BindingDB-show
5,7-Dichlorokynurenic acid monohydrate1779BindingDB-show
6,7-Dinitroquinoxaline-2,3-dione3899541BindingDB-show
71366-32-02733518BindingDB-show
AC1L2QV0126758BindingDB-show
AC1NG5HR4694356BindingDB-show
AC1NUOLW5486548BindingDB-show
AM1447083BindingDB-show
ampa1221BindingDB-show
argiotoxin 636122294BindingDB-show
BN13481675BindingDB-show
BN1447081BindingDB-show
BROMO-WILLARDIINE167842BindingDB-show
Bromochlorotrifluoroethane3562DrugBank-show
Bromochlorotrifluoroethane3562SuperTargetPMID 9443943show
CHEBI:13178844459709BindingDB-show
CHEBI:13179144459711BindingDB-show
CHEBI:14701044281554BindingDB-show
CHEBI:14701544281558BindingDB-show
CHEBI:14701844281561BindingDB-show
CHEBI:14701944281562BindingDB-show
CHEBI:14703844281568BindingDB-show
CHEBI:14703944281569BindingDB-show
CHEBI:14704944281576BindingDB-show
CHEBI:14705044281578BindingDB-show
CHEBI:14708244281590BindingDB-show
CHEBI:14715244281630BindingDB-show
CHEBI:14764344281871BindingDB-show
CHEBI:14767244281886BindingDB-show
CHEBI:14767344281887BindingDB-show
CHEBI:14770844281905BindingDB-show
CHEBI:64751044358120BindingDB-show
CHEMBL109497746886654BindingDB-show
CHEMBL109793918713992BindingDB-show
CHEMBL11201410244106BindingDB-show
CHEMBL11238610244065BindingDB-show
CHEMBL12080844346789BindingDB-show
CHEMBL12119111096831BindingDB-show
CHEMBL12155344346798BindingDB-show
CHEMBL12265644346790BindingDB-show
CHEMBL1235822097178BindingDB-show
CHEMBL1241049927756BindingDB-show
CHEMBL1243144268209BindingDB-show
CHEMBL1244810247474BindingDB-show
CHEMBL1246522100152BindingDB-show
CHEMBL1251010051732BindingDB-show
CHEMBL12603544348419BindingDB-show
CHEMBL1265321710166BindingDB-show
CHEMBL126969985663BindingDB-show
CHEMBL1271521710164BindingDB-show
CHEMBL1273022097105BindingDB-show
CHEMBL1274722097165BindingDB-show
CHEMBL1276122100157BindingDB-show
CHEMBL12762469902629BindingDB-show
CHEMBL127709410155236BindingDB-show
CHEMBL127709510270530BindingDB-show
CHEMBL1277622097194BindingDB-show
CHEMBL1282022097086BindingDB-show
CHEMBL1284144268318BindingDB-show
CHEMBL1289622097211BindingDB-show
CHEMBL1298922100119BindingDB-show
CHEMBL1301744268353BindingDB-show
CHEMBL1301822100063BindingDB-show
CHEMBL1307610437436BindingDB-show
CHEMBL1317622097186BindingDB-show
CHEMBL1321922097148BindingDB-show
CHEMBL14446210656900BindingDB-show
CHEMBL14718210598970BindingDB-show
CHEMBL15215344369308BindingDB-show
CHEMBL15241044368895BindingDB-show
CHEMBL15242544368886BindingDB-show
CHEMBL15273644369235BindingDB-show
CHEMBL15287944369061BindingDB-show
CHEMBL15301744369283BindingDB-show
CHEMBL15399544368884BindingDB-show
CHEMBL15399644368885BindingDB-show
CHEMBL15401244369251BindingDB-show
CHEMBL15418444369047BindingDB-show
CHEMBL1547009799478BindingDB-show
CHEMBL15511910398295BindingDB-show
CHEMBL1579069970950BindingDB-show
CHEMBL16466944377742BindingDB-show
CHEMBL16754844379376BindingDB-show
CHEMBL19308711818375BindingDB-show
CHEMBL21195244413779BindingDB-show
CHEMBL21364510122460BindingDB-show
CHEMBL2464244459795BindingDB-show
CHEMBL26755122097158BindingDB-show
CHEMBL26828422097088BindingDB-show
CHEMBL26870944268202BindingDB-show
CHEMBL26919244369048BindingDB-show
CHEMBL26968422097151BindingDB-show
CHEMBL27348044268369BindingDB-show
CHEMBL27367522100133BindingDB-show
CHEMBL27421944268357BindingDB-show
CHEMBL27533422097119BindingDB-show
CHEMBL27620522100104BindingDB-show
CHEMBL27670944268242BindingDB-show
CHEMBL29361322449297BindingDB-show
CHEMBL3089419837860BindingDB-show
CHEMBL3093009909062BindingDB-show
CHEMBL3098319937279BindingDB-show
CHEMBL31050315840187BindingDB-show
CHEMBL31081415840183BindingDB-show
CHEMBL31089710562939BindingDB-show
CHEMBL31134415337998BindingDB-show
CHEMBL31424844460610BindingDB-show
CHEMBL31779010658567BindingDB-show
CHEMBL31846710752476BindingDB-show
CHEMBL32512410037930BindingDB-show
CHEMBL32831010729534BindingDB-show
CHEMBL3316449795654BindingDB-show
CHEMBL33169644346780BindingDB-show
CHEMBL34552144369248BindingDB-show
CHEMBL34652410132082BindingDB-show
CHEMBL34941344377743BindingDB-show
CHEMBL35022844369062BindingDB-show
CHEMBL35203044369293BindingDB-show
CHEMBL35429510048025BindingDB-show
CHEMBL35597744368910BindingDB-show
CHEMBL35712110081943BindingDB-show
CHEMBL37094111288627BindingDB-show
CHEMBL37264311219775BindingDB-show
CHEMBL38874616659202BindingDB-show
CHEMBL41707444268310BindingDB-show
CHEMBL41853522100072BindingDB-show
CHEMBL42216144369077BindingDB-show
CHEMBL42251544369295BindingDB-show
CHEMBL42320110538709BindingDB-show
CHEMBL43427344369306BindingDB-show
CHEMBL4355829928016BindingDB-show
CHEMBL44045544268224BindingDB-show
CHEMBL44146010824747BindingDB-show
CHEMBL49246924755637BindingDB-show
CHEMBL49263024850230BindingDB-show
CHEMBL5100810398361BindingDB-show
CHEMBL5166010219992BindingDB-show
CHEMBL5597514608128BindingDB-show
CHEMBL585909861035BindingDB-show
CHEMBL5928410541731BindingDB-show
CHEMBL60770544266370BindingDB-show
CHEMBL6280944304811BindingDB-show
CHEMBL7212310084218BindingDB-show
CHEMBL7934815840184BindingDB-show
CHEMBL7945444317999BindingDB-show
CHEMBL8237515840186BindingDB-show
CHEMBL8414215840185BindingDB-show
CHEMBL9486010800053BindingDB-show
CHEMBL9774210823814BindingDB-show
CHEMBL9872310610792BindingDB-show
CX6146451148BindingDB-show
CYCLOTHIAZIDE2910BindingDB-show
D-Glutaminsaeure23327BindingDB-show
DCQX1845BindingDB-show
Desflurane42113DrugBank-show
Desflurane42113SuperTarget-show
Digensaeure10255BindingDB-show
Felbamate3331SuperTargetPMID 15638774show
FLUORO-WILLARDIINE126569BindingDB-show
fluoromethyl hexafluoroisopropyl ether5206DrugBank-show
fluoromethyl hexafluoroisopropyl ether5206SuperTarget-show
Glutamicol33032BindingDB-show
Glutamicol33032DrugBank-show
IODO-WILLARDIINE447196BindingDB-show
Isoflurane3763DrugBank-show
ISOFLURANE4369440DrugBank-show
Isoflurane3763SuperTarget-show
ISOFLURANE4369440SuperTarget-show
Joro spider toxin119582BindingDB-show
LY3394346324635BindingDB-show
Methoxifluranum4116DrugBank-show
Methoxifluranum4116SuperTarget-show
Methylflurether3226DrugBank-show
Methylflurether3226SuperTargetPMID 11020764show
nbqx3272524BindingDB-show
NCGC00025184-016604872BindingDB-show
Phenylaethylbarbitursaeure4763SuperTargetPMID 15638774show
Ted-isoquinoline-3-cooh127894BindingDB-show
THIO-ATPA5289518BindingDB-show
Topiramate5284627SuperTargetPMID 15638774show
Willardiine440053BindingDB-show
Synonyms:
AMPA-selective glutamate receptor 1
GluR-1
GluR-A
GluR-K1
Glutamate receptor 1
Glutamate receptor ionotropic, AMPA 1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
GRIA4_HUMAN79.466.3
GRIA2_RAT79.166.1
GRIA2_HUMAN78.465.7
Q59F93_HUMAN75.763
GRIA3_HUMAN74.563.4
GRIK1_HUMAN56.337.5
GRIK2_HUMAN5436.8
GRIK3_HUMAN5436.2
GRIK2_RAT5436.9
GRIK4_HUMAN50.634.1
GRIK5_HUMAN49.533
GRID2_HUMAN44.325.1
GRID1_HUMAN42.226.1
NMDZ1_RAT41.624
NMDZ1_HUMAN41.523.7
Q5VSF9_HUMAN41.123.1
Q9UPF8_HUMAN4123
Q5VSF5_HUMAN4123.1
Q59H41_HUMAN4022.6
Q5VSF4_HUMAN39.722.1
Q9UPF9_HUMAN39.722
NMD3B_HUMAN34.120
NMD3A_HUMAN3418.9
NMD3A_RAT33.118.3
NMDE3_HUMAN30.518.1
GYRA_HAEIN30.516.2
Q8NHA5_HUMAN29.816.9
HYSA_STRPN29.616.2
NCOAT_HUMAN29.516.1
GRM2_HUMAN29.417.6
Protein-Protein Interactions: