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Name:Proto-oncogene tyrosine-protein kinase Fyn
Uniprot name:FYN_HUMAN
Accession Numbers:P06241 Q16248 Q5R3A6 Q5R3A7 Q8N5D7
EC-Number:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1A0N 1AOT 1AOU 1AVZ 1AZG 1EFN 1FYN 1G83 1M27 1NYF 1NYG 1SHF 1ZBJ 2DQ7
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2,4-dianilino pyrimidine, 225138012BindingDB-show
2-Bromo-4,5-dimethoxybenzoic acid222963BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
3-Thiophenecarboxylic acid6918BindingDB-show
4-anilinoquinazoline deriv. 24708BindingDB-show
4-Nitrohippuric acid17549BindingDB-show
5-Sulfoisophthalic acid80714BindingDB-show
7-Cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine6603792BindingDB-show
ABT-86911485656BindingDB-show
AC1L9J0F446044BindingDB-show
AC1M5WRE2337532BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
benzothiazole analog 13a9933645BindingDB-show
Bosutinib5328940BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:44418144409932BindingDB-show
CHEBI:523095154691BindingDB-show
CHEBI:54743644560358BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL10055110050705BindingDB-show
CHEMBL108099445375865BindingDB-show
CHEMBL108099545375866BindingDB-show
CHEMBL108119811755812BindingDB-show
CHEMBL108765046880136BindingDB-show
CHEMBL108908224822704BindingDB-show
CHEMBL109562644605035BindingDB-show
CHEMBL109562744605037BindingDB-show
CHEMBL1200779797370BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL1315779927718BindingDB-show
CHEMBL1421744269404BindingDB-show
CHEMBL1444544269392BindingDB-show
CHEMBL1528544270599BindingDB-show
CHEMBL1598944270619BindingDB-show
CHEMBL1602812294704BindingDB-show
CHEMBL1640912728243BindingDB-show
CHEMBL166579992262BindingDB-show
CHEMBL19813620817416BindingDB-show
CHEMBL19823920817330BindingDB-show
CHEMBL19936944406037BindingDB-show
CHEMBL19943844406079BindingDB-show
CHEMBL19981344406138BindingDB-show
CHEMBL19981644406058BindingDB-show
CHEMBL20042444405918BindingDB-show
CHEMBL20058722346947BindingDB-show
CHEMBL20914811467730BindingDB-show
CHEMBL22397111590078BindingDB-show
CHEMBL23254218451036BindingDB-show
CHEMBL23395811238420BindingDB-show
CHEMBL23534516739279BindingDB-show
CHEMBL24537716747696BindingDB-show
CHEMBL24576944440254BindingDB-show
CHEMBL24596844440256BindingDB-show
CHEMBL24616644440259BindingDB-show
CHEMBL27354744269518BindingDB-show
CHEMBL27492644270586BindingDB-show
CHEMBL27734744270641BindingDB-show
CHEMBL27774310467257BindingDB-show
CHEMBL29175923518511BindingDB-show
CHEMBL29293010482445BindingDB-show
CHEMBL29371244299325BindingDB-show
CHEMBL29618544299360BindingDB-show
CHEMBL29856644299304BindingDB-show
CHEMBL30085344299236BindingDB-show
CHEMBL30114344299176BindingDB-show
CHEMBL30127144299339BindingDB-show
CHEMBL31955623532567BindingDB-show
CHEMBL32782044324728BindingDB-show
CHEMBL32803444324769BindingDB-show
CHEMBL32890744324648BindingDB-show
CHEMBL36462311153014BindingDB-show
CHEMBL37038344405977BindingDB-show
CHEMBL37067044406001BindingDB-show
CHEMBL37129520817403BindingDB-show
CHEMBL37145920817425BindingDB-show
CHEMBL37305420817327BindingDB-show
CHEMBL38293944406078BindingDB-show
CHEMBL39015616220354BindingDB-show
CHEMBL39392911631681BindingDB-show
CHEMBL39542744440261BindingDB-show
CHEMBL39566418451024BindingDB-show
CHEMBL39566511753519BindingDB-show
CHEMBL41616644270657BindingDB-show
CHEMBL41635310241671BindingDB-show
CHEMBL43090244324757BindingDB-show
CHEMBL43218944320769BindingDB-show
CHEMBL43264944324716BindingDB-show
CHEMBL43613711719421BindingDB-show
CHEMBL44021344405919BindingDB-show
CHEMBL46649615295578BindingDB-show
CHEMBL46707925206064BindingDB-show
CHEMBL46812544575073BindingDB-show
CHEMBL47781724766030BindingDB-show
CHEMBL47983544570884BindingDB-show
CHEMBL48124844575127BindingDB-show
CHEMBL51141025207521BindingDB-show
CHEMBL51541616663089BindingDB-show
CHEMBL51911344575126BindingDB-show
CHEMBL5428310413508BindingDB-show
CHEMBL5549644299321BindingDB-show
CHEMBL5559444299203BindingDB-show
CHEMBL5610944299354BindingDB-show
CHEMBL5656910320381BindingDB-show
CHEMBL56907845486342BindingDB-show
CHEMBL5714344299338BindingDB-show
CHEMBL590429803350BindingDB-show
CHEMBL60079546232443BindingDB-show
CHEMBL60247146232555BindingDB-show
CHEMBL60247246232556BindingDB-show
CHEMBL672379823235BindingDB-show
CHEMBL8800944320732BindingDB-show
CHEMBL9000244321260BindingDB-show
CHEMBL9029444324649BindingDB-show
CHEMBL9097644324647BindingDB-show
CHEMBL9148844324729BindingDB-show
CHIR-26511656518BindingDB-show
CID 1177508610275163BindingDB-show
CID 98443209844320BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Dasatinib3062316DrugBank-show
Deoxyepinephrine681BindingDB-show
Dipropyldopamine hydrobromide3106BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Essigsaeure176BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
JAK Inhibitor I5494425BindingDB-show
Kinome_248146224684BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_71446886323BindingDB-show
L2G9549184BindingDB-show
L3G9549185BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
Leucoharmine5280953BindingDB-show
lfm-a139549280BindingDB-show
MLN805411712649BindingDB-show
N,N-Dipropyl-6,7-adtn125246BindingDB-show
nchembio.117-comp91400BindingDB-show
nchembio859-comp1644243BindingDB-show
nchembio866-comp1015159379BindingDB-show
nchembio866-comp1115159380BindingDB-show
nchembio866-comp1215159381BindingDB-show
nchembio866-comp1315159382BindingDB-show
nchembio866-comp410401956BindingDB-show
nchembio866-comp515159374BindingDB-show
nchembio866-comp615159375BindingDB-show
nchembio866-comp715159376BindingDB-show
nchembio866-comp815159377BindingDB-show
nchembio866-comp915159378BindingDB-show
NSC656255338490BindingDB-show
Pazopanib10113978BindingDB-show
Pelitinib6445562BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
pp1 analog4877BindingDB-show
Pyrrolo[2,3-d]pyrimidine 16539952BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
U-99194A maleate5626BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
p59-Fyn
Proto-oncogene tyrosine-protein kinase Fyn
Protooncogene Syn
SLK
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
YES_HUMAN81.672.5
SRC_RAT80.268.9
SRC_HUMAN79.267.8
SRC_RSVSE73.362.8
HCK_HUMAN69.755.5
LCK_HUMAN63.150.3
CSK_HUMAN48.131.7
ITK_HUMAN43.927.5
BTK_HUMAN40.226.8
ZAP70_HUMAN39.927.1
KSYK_HUMAN39.325
Q9Y6B5_HUMAN34.219
ILK_CAVPO33.420.5
GSHB_YEAST33.118.7
PPARD_HUMAN32.818.1
Q9XB61_ERWCA32.118.3
KPC1_LYTPI3219.4
RAF1_RAT31.919.9
ERR2_HUMAN31.519
ESR1_MOUSE31.417.6
KPCT_HUMAN31.218.2
DDX6_HUMAN31.218.6
RAF1_MOUSE3119.5
ARAF_HUMAN30.920.9
DCDA_METJA30.917.5
Q4VA93_MOUSE30.916.8
ESR1_HUMAN30.717.4
INO1_YEAST30.518.5
F264_RAT30.518.5
CATA_HUMAN30.516.3
Protein-Protein Interactions:
Uniprot nameSource
ZF106_HUMANPMID 16713569
ZAP70_HUMAN2 PMIDs
YTDC1_HUMAN3 PMIDs
XRCC1_HUMAN4 PMIDs
WNK2_HUMAN5 PMIDs
WIPF1_HUMAN6 PMIDs
WASP_HUMAN7 PMIDs
WASF4_HUMAN8 PMIDs
WASF2_HUMAN9 PMIDs
WASF1_HUMAN10 PMIDs
VP13A_HUMAN11 PMIDs
VGFR2_HUMAN12 PMIDs
VGFR1_HUMAN13 PMIDs
VAV_HUMAN14 PMIDs
UCK2_HUMAN15 PMIDs
U119A_HUMAN16 PMIDs
TYRO3_HUMAN17 PMIDs
TYK2_HUMAN18 PMIDs
TXK_HUMAN19 PMIDs
TULP4_HUMAN20 PMIDs
TULP1_HUMAN21 PMIDs
TSKS_HUMAN22 PMIDs
TRPV4_HUMAN23 PMIDs
TRPC6_HUMAN24 PMIDs
TRI39_HUMAN25 PMIDs
TRAT1_HUMAN26 PMIDs
TRAIP_HUMAN27 PMIDs
TNR6_HUMAN28 PMIDs
TNFL6_HUMAN29 PMIDs
TM1L1_HUMAN30 PMIDs
THY1_HUMAN31 PMIDs
TGON2_HUMAN32 PMIDs
TF3A_HUMAN33 PMIDs
TDRD1_HUMAN34 PMIDs
TCGAP_HUMAN35 PMIDs
TBA4A_HUMAN36 PMIDs
TBA3C_HUMAN37 PMIDs
TBA1B_HUMAN38 PMIDs
TAU_HUMAN39 PMIDs
SYUA_HUMAN40 PMIDs
SYNJ2_HUMAN41 PMIDs
SUV92_HUMAN42 PMIDs
STF1_HUMAN43 PMIDs
STAT1_HUMAN44 PMIDs
SREC2_HUMAN45 PMIDs
SRC_HUMAN46 PMIDs
SPN90_HUMAN47 PMIDs
SPHK2_HUMAN48 PMIDs
SPHK1_HUMAN49 PMIDs
SP1_HUMAN50 PMIDs
SOS2_HUMAN51 PMIDs
SOS1_HUMAN52 PMIDs
SON_HUMAN53 PMIDs
SOCS1_HUMAN54 PMIDs
SNX8_HUMAN55 PMIDs
SNX3_HUMAN56 PMIDs
SNX17_HUMAN57 PMIDs
SNX12_HUMAN58 PMIDs
SLAF1_HUMAN59 PMIDs
SKAP2_HUMAN60 PMIDs
SKAP1_HUMAN61 PMIDs
SIT1_HUMAN62 PMIDs
SHRM2_HUMAN63 PMIDs
SHC1_HUMAN64 PMIDs
SHAN3_HUMAN65 PMIDs
SH2B2_HUMAN66 PMIDs
SH21A_HUMAN67 PMIDs
SF3B4_HUMAN68 PMIDs
SEM7A_HUMAN69 PMIDs
SELN_HUMAN70 PMIDs
SDC3_HUMAN71 PMIDs
RTN4_HUMAN72 PMIDs
RRAS_HUMAN73 PMIDs
RPP38_HUMAN74 PMIDs
RPGF1_HUMAN75 PMIDs
RL10_HUMAN76 PMIDs
RIN3_HUMAN77 PMIDs
RIMS2_HUMAN78 PMIDs
RIMS1_HUMAN79 PMIDs
RICS_HUMAN80 PMIDs
RFRP_HUMAN81 PMIDs
RASH_HUMAN82 PMIDs
RASA1_HUMAN83 PMIDs
RASA1_HUMAN84 PMIDs
RAF1_HUMAN85 PMIDs
Q3ZCU5_HUMAN86 PMIDs
PTPRZ_HUMAN87 PMIDs
PTPRF_HUMAN88 PMIDs
PTPRE_HUMAN89 PMIDs
PTPRA_HUMAN90 PMIDs
PTN5_HUMAN91 PMIDs
PTN4_HUMAN92 PMIDs
PTN11_HUMAN93 PMIDs
PRIC3_HUMAN94 PMIDs
PRAX_HUMAN95 PMIDs
PPR3D_HUMAN96 PMIDs
PPAC_HUMAN97 PMIDs
PLD2_HUMAN98 PMIDs
PLCG2_HUMAN99 PMIDs
PLCG1_HUMAN100 PMIDs
PLAK_HUMAN101 PMIDs
PKD1_HUMAN102 PMIDs
PGFRB_HUMAN103 PMIDs
PDIA2_HUMAN104 PMIDs
PDE4D_HUMAN105 PMIDs
PAXI_HUMAN106 PMIDs
PAX7_HUMAN107 PMIDs
PAX3_HUMAN108 PMIDs
PAK2_HUMAN109 PMIDs
PAG1_HUMAN110 PMIDs
P85B_HUMAN111 PMIDs
P85B_HUMAN112 PMIDs
P85A_HUMAN113 PMIDs
P85A_HUMAN114 PMIDs
ORC1_HUMAN115 PMIDs
O14909_HUMAN116 PMIDs
NTRK2_HUMAN117 PMIDs
NPHN_HUMAN118 PMIDs
NMT1_HUMAN119 PMIDs
NMDE2_HUMAN120 PMIDs
NMDE1_HUMAN121 PMIDs
NKX21_HUMAN122 PMIDs
NFS1_HUMAN123 PMIDs
NFASC_HUMAN124 PMIDs
NELFB_HUMAN125 PMIDs
NEK8_HUMAN126 PMIDs
NCKX1_HUMAN127 PMIDs
NCK1_HUMAN128 PMIDs
NCAM1_HUMAN129 PMIDs
NCAM1_HUMAN130 PMIDs
NBEA_HUMAN131 PMIDs
MYPT1_HUMAN132 PMIDs
MUC18_HUMAN133 PMIDs
MOS_HUMAN134 PMIDs
MLL4_HUMAN135 PMIDs
MEPE_HUMAN136 PMIDs
MED28_HUMAN137 PMIDs
MED14_HUMAN138 PMIDs
MAP2_HUMAN139 PMIDs
MAG_HUMAN140 PMIDs
MAAI_HUMAN141 PMIDs
M4K5_HUMAN142 PMIDs
M4K1_HUMAN143 PMIDs
LTBP2_HUMAN144 PMIDs
LRBA_HUMAN145 PMIDs
LEUK_HUMAN146 PMIDs
LCP2_HUMAN147 PMIDs
LAT_HUMAN148 PMIDs
LAP2B_HUMAN149 PMIDs
L2GL1_HUMAN150 PMIDs
KSYK_HUMAN151 PMIDs
KPCZ_HUMAN152 PMIDs
KPCT_HUMAN153 PMIDs
KPCL_HUMAN154 PMIDs
KPCE_HUMAN155 PMIDs
KPCD_HUMAN156 PMIDs
KIT_HUMAN157 PMIDs
KI67_HUMAN158 PMIDs
KHDR1_HUMAN159 PMIDs
JAK2_HUMAN160 PMIDs
ITPR1_HUMAN161 PMIDs
ITK_HUMAN162 PMIDs
ITB4_HUMAN163 PMIDs
ITB4_HUMAN164 PMIDs
ITA6_HUMAN165 PMIDs
IRS1_HUMAN166 PMIDs
IL7RA_HUMAN167 PMIDs
IL3RB_HUMAN168 PMIDs
IL3RA_HUMAN169 PMIDs
IL2RB_HUMAN170 PMIDs
ICAL_HUMAN171 PMIDs
I20L2_HUMAN172 PMIDs
HXC8_HUMAN173 PMIDs
HS90A_HUMAN174 PMIDs
HS90A_HUMAN175 PMIDs
HNRPR_HUMAN176 PMIDs
HNRPK_HUMAN177 PMIDs
HEXA_HUMAN178 PMIDs
HDAC6_HUMAN179 PMIDs
HCN4_HUMAN180 PMIDs
HCN2_HUMAN181 PMIDs
GUC2D_HUMAN182 PMIDs
GRB2_HUMAN183 PMIDs
GRB10_HUMAN184 PMIDs
GRAP_HUMAN185 PMIDs
GPVI_HUMAN186 PMIDs
GPR63_HUMAN187 PMIDs
GPR45_HUMAN188 PMIDs
GNS_HUMAN189 PMIDs
GCR_HUMAN190 PMIDs
GCR_HUMAN191 PMIDs
GCF_HUMAN192 PMIDs
GBLP_HUMAN193 PMIDs
GASR_HUMAN194 PMIDs
GABR1_HUMAN195 PMIDs
GAB3_HUMAN196 PMIDs
G3BP1_HUMAN197 PMIDs
FYN_HUMAN198 PMIDs
FYB_HUMAN199 PMIDs
FOXF2_HUMAN200 PMIDs
FNBP4_HUMAN201 PMIDs
FLOT2_HUMAN202 PMIDs
FLOT1_HUMAN203 PMIDs
FLNC_HUMAN204 PMIDs
FLNA_HUMAN205 PMIDs
FINC_HUMAN205 PMIDs
FCG2B_HUMAN206 PMIDs
FCG2A_HUMAN207 PMIDs
FCER2_HUMAN208 PMIDs
FANCA_HUMAN209 PMIDs
FAK2_HUMAN210 PMIDs
FAK2_HUMAN211 PMIDs
FAK1_HUMAN212 PMIDs
FAK1_HUMAN213 PMIDs
F110A_HUMAN214 PMIDs
EXTL3_HUMAN215 PMIDs
EVL_HUMAN216 PMIDs
EPS15_HUMAN217 PMIDs
EPHB3_HUMAN218 PMIDs
EPHA8_HUMAN219 PMIDs
EPHA4_HUMAN220 PMIDs
EPHA3_HUMAN221 PMIDs
E41L3_HUMAN222 PMIDs
DYN3_HUMAN223 PMIDs
DYLT1_HUMAN224 PMIDs
DUS15_HUMAN225 PMIDs
DPOD1_HUMAN226 PMIDs
DOK4_HUMAN227 PMIDs
DOK3_HUMAN228 PMIDs
DOK1_HUMAN229 PMIDs
DOCK3_HUMAN230 PMIDs
DOCK1_HUMAN231 PMIDs
DNSL2_HUMAN232 PMIDs
DLX4_HUMAN233 PMIDs
DLGP4_HUMAN234 PMIDs
DLGP3_HUMAN235 PMIDs
DLGP2_HUMAN236 PMIDs
DLGP1_HUMAN237 PMIDs
DLG4_HUMAN238 PMIDs
DLG4_HUMAN239 PMIDs
DKKL1_HUMAN240 PMIDs
DDX41_HUMAN241 PMIDs
DCE1_HUMAN242 PMIDs
DAG1_HUMAN243 PMIDs
DAF_HUMAN244 PMIDs
DAB2_HUMAN245 PMIDs
CTND2_HUMAN246 PMIDs
CTND1_HUMAN247 PMIDs
CTNB1_HUMAN248 PMIDs
CTLA4_HUMAN249 PMIDs
CSMD2_HUMAN250 PMIDs
CSK_HUMAN251 PMIDs
CSF1R_HUMAN252 PMIDs
CRK_HUMAN253 PMIDs
CRKL_HUMAN254 PMIDs
CP4F2_HUMAN255 PMIDs
CO6_HUMAN256 PMIDs
CNTP1_HUMAN257 PMIDs
CNTN1_HUMAN258 PMIDs
CNTFR_HUMAN259 PMIDs
CNN3_HUMAN260 PMIDs
CNN1_HUMAN261 PMIDs
CKAP5_HUMAN262 PMIDs
CENPA_HUMAN263 PMIDs
CELR3_HUMAN264 PMIDs
CDKL5_HUMAN265 PMIDs
CDK5_HUMAN266 PMIDs
CDC2_HUMAN267 PMIDs
CD79B_HUMAN268 PMIDs
CD79A_HUMAN269 PMIDs
CD5_HUMAN270 PMIDs
CD48_HUMAN271 PMIDs
CD45_HUMAN272 PMIDs
CD44_HUMAN273 PMIDs
CD3Z_HUMAN274 PMIDs
CD36_HUMAN275 PMIDs
CD2_HUMAN276 PMIDs
CD2AP_HUMAN277 PMIDs
CD226_HUMAN278 PMIDs
CD20_HUMAN279 PMIDs
CD19_HUMAN280 PMIDs
CCR10_HUMAN281 PMIDs
CBL_HUMAN282 PMIDs
CBL_HUMAN283 PMIDs
CBL_HUMAN284 PMIDs
CBL_HUMAN285 PMIDs
CBLC_HUMAN286 PMIDs
CBLB_HUMAN287 PMIDs
CAV1_HUMAN288 PMIDs
CASP8_HUMAN289 PMIDs
CASP3_HUMAN290 PMIDs
CASL_HUMAN291 PMIDs
CAF1A_HUMAN292 PMIDs
CADH1_HUMAN293 PMIDs
CAC1F_HUMAN294 PMIDs
BTK_HUMAN295 PMIDs
BRPF3_HUMAN296 PMIDs
BRCA2_HUMAN297 PMIDs
BMP8B_HUMAN298 PMIDs
BCL3_HUMAN299 PMIDs
BCAR1_HUMAN300 PMIDs
BAZ2A_HUMAN301 PMIDs
ATX1_HUMAN302 PMIDs
ASB16_HUMAN303 PMIDs
ASAP2_HUMAN304 PMIDs
ASAP1_HUMAN305 PMIDs
ARHGB_HUMAN306 PMIDs
APOL5_HUMAN307 PMIDs
ANXA6_HUMAN308 PMIDs
AKAP6_HUMAN309 PMIDs
AIRE_HUMAN310 PMIDs
ADDB_HUMAN311 PMIDs
ADA15_HUMAN312 PMIDs
ACK1_HUMAN313 PMIDs
ACHA7_HUMAN314 PMIDs
ABL2_HUMAN315 PMIDs
ABL1_HUMAN316 PMIDs
5HT6R_HUMAN317 PMIDs
3BP2_HUMAN318 PMIDs